Dataset Overview
RBPPPIL4
Knock-MethodshRNA
RBP FamilyRRM_1
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR851KEX
PlatformHiSeq
Pubmed ID32252787

PPIL4 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of PPIL4
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of PPIL4


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr169200168AT0.00908C16orf72+FALSEAluSx1SINE,Alu
chr125168124GC0.00669CLIC4+FALSE
chr1109242607GA0.00652PRPF38B+FALSE
chr19161231TC0.00481.FALSEAluSxSINE,Alu
chr116893686GC0.00171NBPF1-FALSE
chr4139088295CT0.00537SLC7A11-AS1,SLC7A11+,-FALSE
chr817796338GT4.50000E-10PCM1+FALSE
chr1244869241CA0.00213DESI2+FALSE
chr1226333556CA0.00250ACBD3-FALSE(CAAAA)nSINE,Alu
chr1244572644GC0.00033ADSS-FALSE
chr1761502463TG0.00370TANC2+FALSE
chr3183901281GA4.84515E-09AP2M1+FALSE
chr932425898TC0.00177ACO1+FALSE
chr744917278TC0.00461PURB-TRUEAluSzSINE,Alu
chr110520117TC0.00078.FALSEAluSxSINE,Alu
chr1789050GA0.00449LINC01128+FALSE
chr1120165040TC0.00195ZNF697-FALSE
chr255459824CT0.00763RPS27A+FALSE
chr2241252612GA0.00561ST13-FALSE
chr1227845283CA0.00809ZNF678+FALSE
chr1160967856TC0.00027F11R-TRUEAluSpSINE,Alu
chr534189578TC0.00378.FALSE
chr1230461079GA9.74527E-05PGBD5-FALSE
chr145976723TC0.00239MMACHC,PRDX1+,-FALSE
chr144035352CT0.00055PTPRF+FALSE
chr110517691TC9.61087E-05.FALSEAluSx1SINE,Alu
chr1075008731TC8.90942E-06DNAJC9-AS1,MRPS16+,-FALSEAluJrSINE,Alu
chr111979815AC0.00072KIAA2013-FALSE
chr1100490275AG0.00142SLC35A3+TRUEAluSc5SINE,Alu
chr812879707TG0.00780KIAA1456+FALSE
chr543575009TC0.00498NNT-AS1-TRUEAluSq2SINE,Alu
chr145280426AG0.00802.FALSEAluSxSINE,Alu
chr2101635538CT0.00069TBC1D8,RPL31+,-FALSECharlie17SINE,Alu
chr2208620129AG0.00167CCNYL1+TRUEEutTc1-N1SINE,Alu
chr161922059CA0.00132NFIA+FALSE(A)nSINE,Alu
chr3142776250AC0.00926U2SURP+FALSE
chr119545142AG0.00071LOC101927895,EMC1+,-FALSE
chr119543356TC0.00256LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr5118174735TC0.00046DTWD2-TRUEAluYSINE,Alu
chr1165544381TC0.00433AP5B1-TRUEAluJbSINE,Alu
chr136770950AG0.00118THRAP3+FALSE
chr120826781CT1.74444E-05MUL1-FALSE
chr541917695CT0.00546C5orf51+FALSE
chr1148594563GT0.00169NBPF15+FALSE
chr1145689611CA0.00104NBPF20,NBPF10+FALSEAluSgSINE,Alu
chr19328094AG0.00107H6PD+TRUEAluJrSINE,Alu
chr1919791274AG7.64703E-05ZNF101+TRUEAluSq2SINE,Alu
chr224494671TC0.00244ITSN2-FALSE(TATCCT)nSINE,Alu
chr6150046603TC0.00763NUP43-TRUEAluSq2SINE,Alu
chr3191111160AG4.43846E-07CCDC50+FALSE
chr19331227AG0.00181H6PD+TRUEAluSxSINE,Alu
chr237431521AG0.00783CEBPZOS,CEBPZ+,-FALSEAluScSINE,Alu
chr1743364293CG0.00144MAP3K14-FALSE
chr110521254TC0.00023DFFA-TRUEAluYSINE,Alu
chr128836975AG0.00023SNHG3,RCC1+TRUEAluScSINE,Alu
chr112024235CT0.00395PLOD1+FALSE
chr642856917AG0.00148RPL7L1+TRUEAluSpSINE,Alu
chr1214529170TC0.00120PTPN14-TRUE
chr4155456608AG0.00734PLRG1-FALSEL1MC5SINE,Alu
chr19644562AG0.00337.FALSEAluSxSINE,Alu
chr136067821TC8.78017E-05PSMB2-TRUEAluSzSINE,Alu
chr11344893AG0.00186.FALSEAluSgSINE,Alu
chr286249961TC0.00292LOC90784-TRUEAluJrSINE,Alu
chr128904397CG0.00125TRNAU1AP+FALSE
chr531553951CT0.00240C5orf22+FALSE
chr643582795AG0.00087POLH+TRUEAluSx1SINE,Alu
chr154871874CT1.50809E-06SSBP3-FALSE
chr8144940792GC9.20360E-05EPPK1-FALSE
chr2207146631CA9.52905E-05ZDBF2+FALSE
chr162627191AG0.00146PATJ+TRUEAluSxSINE,Alu
chr128826023AG0.00143PHACTR4+FALSEAluJbSINE,Alu
chr1180169330CT0.00015FLJ23867+FALSEMIRSINE,Alu
chr1121133733GA0.00455SRGAP2-AS1,SRGAP2B,SRGAP2C+,-FALSEL1MB4SINE,Alu
chr7143003524GT3.66232E-05CASP2+FALSEAluYSINE,Alu
chr133148740AG0.00210SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr1179989742GC0.00019CEP350+FALSE
chr1757279273AG0.00513PRR11+TRUEAluSq2SINE,Alu
chr4189026673AG0.00994TRIML2-FALSE
chr12120899702TA0.00967GATC,SRSF9+,-FALSE
chr826435508CT0.00106DPYSL2+FALSE(TC)nSINE,Alu
chr1205686523GT0.00640NUCKS1-FALSE
chr2218572742AG8.48972E-05PEX26+TRUEAluYf1SINE,Alu
chr1912742290AG0.00564.FALSEAluSxSINE,Alu
chr193827995CT0.00236DR1+FALSE
chr125570563AT0.00276RSRP1-FALSEAluSINE,Alu
chr128825415AG1.13446E-06PHACTR4+TRUEAluSgSINE,Alu
chr1146650289CT0.00967PDIA3P1+FALSE
chr1205687358TC0.00432NUCKS1-FALSE(T)nSINE,Alu
chr3183476685GA0.00032YEATS2+FALSE
chr671298815TA0.00287.FALSE
chr99442082TG0.00052PTPRD-FALSE7SLRNASINE,Alu
chr2219100706AG0.00874ARPC2+TRUEAluSx1SINE,Alu
chr1423795204GT0.00938BCL2L2-PABPN1,PABPN1+FALSE
chr2121749583TC0.00120GLI2+FALSE
chr1075009651TC0.00558DNAJC9-AS1,MRPS16+,-FALSEAluScSINE,Alu
chr144402565GA0.00010ARTN+FALSE
chr1765335316TC0.00296PSMD12-TRUEAluSxSINE,Alu
chr119566382AG0.00513LOC101927895,EMC1+,-FALSE
chr163924020CT0.00139ITGB3BP-FALSE
chr136322433GA0.00663AGO4+FALSE
chr110093457CT0.00777UBE4B+FALSE
chr110520683TC0.00124DFFA-TRUEAluSc8SINE,Alu
chr319992432GT0.00017RAB5A+FALSE
chr1146628742TG0.00102PRKAB2-FALSE
chr1913884084AG0.00843MRI1+TRUEAluSzSINE,Alu
chr150883798TC0.00156DMRTA2-FALSE
chr1144931392GA0.00172NBPF20,PDE4DIP+,-FALSE
chr314986447TC2.03372E-08FGD5-AS1-TRUEAluSq2SINE,Alu
chr299812464AG1.88485E-05MRPL30+TRUEAluSxSINE,Alu
chr2110373919GA0.00240SOWAHC+FALSE
chr755433880GC0.00115LANCL2+FALSE
chr110517672TC0.00070.FALSEAluSx1SINE,Alu
chr16279950AG0.00541RNF207+TRUEAluSpSINE,Alu
chr1921131571AG0.00120ZNF85+FALSE
chr116933643AG0.00279NBPF1-FALSEGA-richSINE,Alu
chr146077218AG0.00783NASP+TRUEAluSc8SINE,Alu
chr132637063CT0.00071KPNA6+FALSE
chr646128910AG0.00782ENPP5-FALSE(GT)nSINE,Alu
chr178445292AG7.48186E-07DNAJB4+FALSE
chr3124948047CG0.00670ZNF148-FALSE
chr128835934AG0.00193SNHG3,RCC1+TRUEAluSx4SINE,Alu
chr190478690AC0.00035ZNF326+FALSE
chr8145139727CT0.00458GPAA1+FALSE
chr1220231370TC0.00826RNU5F-1,BPNT1+,-FALSEAluYSINE,Alu
chr1144594170CT0.00636NBPF20+FALSE
chr178201745GT0.00140USP33-FALSE
chr310192798AG0.00722VHL+TRUEAluSx1SINE,Alu
chr16259433GA0.00522RPL22-FALSEG-richSINE,Alu
chr1145283718GA0.00897NBPF20,NOTCH2NL+FALSE
chr1931939GA0.00428.FALSE
chr4190878580AG0.00097FRG1+FALSE
chr11469546GA0.00331ATAD3A+FALSE
chr199164434GA0.00309SNX7+FALSE
chr11419690AG0.00464ATAD3B+TRUEAluYk2SINE,Alu
chr560050122AT0.00272ELOVL7-FALSE
chr19161365TC4.68504E-05.FALSEAluSxSINE,Alu
chr764441632AT0.00038ZNF117-FALSE
chr178414310CA9.26299E-05FUBP1-FALSE
chr333909024AT0.00134PDCD6IP+FALSE
chr735840866AG0.00947SEPT7+FALSE
chr743665371AT0.00430STK17A,COA1+,-FALSE(AG)nSINE,Alu
chr1470838369TC0.00015SYNJ2BP-COX16,SYNJ2BP-TRUEAluSgSINE,Alu
chr116933135GT2.86961E-06NBPF1-FALSEL1MC2SINE,Alu
chr2234386134AG0.00196USP40-FALSE
chr1958357211AG0.00041ZNF587B+TRUEAluSx3SINE,Alu
chr9132268942AG0.00104LINC00963+TRUEAluYf1SINE,Alu
chr1153700841AG0.00508INTS3+FALSE
chr5132440285CG0.00322HSPA4+FALSE
chr1207942427AG0.00822CD46+TRUEAluSg4SINE,Alu
chr1051612914TC0.00063TIMM23B,TIMM23+,-FALSE
chr2203745105TC0.00644.FALSEAluSxSINE,Alu
chr724731065CT0.00414MPP6+FALSE(TGTATG)nSINE,Alu
chr1145369556AG0.00373NBPF20,NBPF10+TRUEL1MC4SINE,Alu
chr577655330TC0.00050SCAMP1-AS1-TRUEAluSx4SINE,Alu
chr29630231CT0.00895ADAM17-FALSE
chr9132900076TC5.65714E-05GPR107+FALSE
chr10101992298TC0.00409CWF19L1-TRUEAluSq2SINE,Alu
chr4177252238AG9.63526E-05SPCS3+TRUE
chr381698130TC2.93981E-08GBE1-FALSE
chr45743512TC0.00045EVC+FALSE
chr135899684CT0.00051KIAA0319L-FALSEAluSc8SINE,Alu
chr1143189473CA0.00572LOC102723769-FALSE
chr133960062AG0.00437ZSCAN20+FALSE
chr2206858904CT0.00783INO80D-FALSE
chr141972198AT0.00276HIVEP3-FALSE
chr314986111TC0.00999FGD5-AS1-TRUEFLAM_CSINE,Alu
chr775115154CT0.00405POM121C-FALSE
chr116812082AG0.00545CROCCP3-FALSE
chr4128756579AG0.00501.FALSEAluSxSINE,Alu
chr110318652CG0.00047KIF1B+FALSE
chr11650801TC0.00359CDK11B,CDK11A-FALSE
chr1145689717AG7.73781E-05NBPF20,NBPF10+TRUEAluJbSINE,Alu
chr119543456TC0.00011LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr2219100202CT0.00027ARPC2+FALSEAluJrSINE,Alu
chr1949232226GA0.00887RASIP1-FALSE
chr10115526177AG0.00237PLEKHS1+FALSE
chr1179044206AG0.00458FAM20B+TRUEAluSxSINE,Alu
chr1150939883AG0.00472CERS2-FALSE
chr1288454641AT0.00753CEP290-FALSE
chr5130494984AT0.00018HINT1-FALSE
chr1116609833GA0.00773SLC22A15+FALSE
chr2113334241AG0.00388POLR1B+TRUE
chr19331101AG3.95613E-06H6PD+FALSEAluSxSINE,Alu
chr1475202402AG0.00141FCF1+TRUEAluScSINE,Alu
chr133149443AG0.00013SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr270506338CT0.00026PCYOX1+FALSE
chr9116139063GC0.00321HDHD3-FALSE
chr342253664CT0.00065TRAK1+FALSE
chr4108832727TC0.00071SGMS2,LOC101929595+,-FALSE
chr117326540GA0.00120ATP13A2-FALSE
chr517276088CA0.00171BASP1+FALSE(TC)nSINE,Alu
chr16282401TC0.00665ICMT-TRUEAluSzSINE,Alu
chr167874696TC0.00014SERBP1-TRUEAluSx3SINE,Alu
chr238971639AT0.00019SRSF7-FALSE
chr19161090AG0.00068.FALSEAluJbSINE,Alu
chr1144829799GC2.98942E-05NBPF20,NBPF9+FALSEL1MC4SINE,Alu
chr133148006AG0.00110SYNC,RBBP4+,-FALSEAluSxSINE,Alu
chr3155658362CT0.00807.FALSEMIR3SINE,Alu
chr16583036TC0.00296NOL9-TRUEAluSx4SINE,Alu
chr138463218GA1.86271E-07FHL3-FALSE
chr1298942665AG1.31028E-05TMPO+TRUEAluScSINE,Alu
chr3101542436AG0.00023NXPE3+TRUEAluJrSINE,Alu
chr1150548883AC0.00255MCL1-FALSE
chr19163328TC0.00287.FALSEAluSpSINE,Alu
chr147184569GC0.00509EFCAB14-FALSE
chr232582399TG0.00147BIRC6+FALSE(GGC)nSINE,Alu
chr120519808GA0.00882UBXN10+FALSE
chr3172365720CT3.67728E-06NCEH1-FALSE
chr1154554947TG0.00511ADAR-FALSE
chr388103602CA0.00284CGGBP1-FALSE
chr128261661GA0.00872SMPDL3B+FALSE
chr286252080TC0.00017POLR1A-TRUEAluSq2SINE,Alu
chr131905887AC0.00245SERINC2+FALSE
chr344791554TC7.29341E-07KIAA1143-FALSEAluJrSINE,Alu
chr1144833405CA0.00345NBPF20+FALSEL1MEcSINE,Alu
chr237329307TC0.00137.FALSEAluJr4SINE,Alu
chr155207985GA0.00156MROH7-TTC4,TTC4+FALSE
chr2242384368GA0.00031FARP2+FALSEAluJrSINE,Alu
chr286252214TC0.00930POLR1A-TRUEAluSq2SINE,Alu
chr310290515GA0.00904TATDN2+FALSE
chr2203744240TC0.00595.FALSEAluSxSINE,Alu
chr133071043AG4.49838E-05ZBTB8A+TRUEAluSx1SINE,Alu
chr1109746825AG0.00094KIAA1324+TRUEAluJbSINE,Alu
chr192426238TG0.00129TIMM13,TMPRSS9+,-FALSE
chr126143726GT0.00556SEPN1+FALSEAluSxSINE,Alu
chr210270775GT0.00953RRM2+FALSEAluSxSINE,Alu
chr72294401AG0.00035SNX8-FALSE
chr2118583874CG0.00569DDX18+FALSE
chr220450819TC0.00807PUM2-TRUE
chr110520378TC8.57705E-06.FALSEAluSx1SINE,Alu
chr136068370TC0.00067PSMB2-TRUEAluScSINE,Alu
chr116893686GC0.00138NBPF1-FALSE
chr167874859TC0.00209SERBP1-TRUEAluSxSINE,Alu
chr1155695985AG0.00031DAP3+TRUEAluSpSINE,Alu
chr11126147713CG0.00384FOXRED1+FALSE
chr5204215AG0.00872.FALSEMER68SINE,Alu
chr1153585584GA0.00011S100A16-FALSE
chr3191075902CT1.38271E-08CCDC50+FALSE
chr1114938105TA0.00430TRIM33-FALSE
chr1773939212TC0.00376ACOX1-TRUEAluSx1SINE,Alu
chr1146647196TC0.00241.FALSETHE1DSINE,Alu
chr236706788CG0.00481CRIM1+FALSE
chr1326500AG0.00189.FALSE
chr111119950GA4.66412E-05SRM-FALSE
chr152520892AC0.00292TXNDC12-FALSE
chr310193358AG1.11864E-10VHL+TRUEL1ME4aSINE,Alu
chr1565442483TC0.00523CLPX-TRUEAluSg4SINE,Alu
chr1114443474AG9.14620E-06AP4B1-AS1,AP4B1+,-FALSEAluSpSINE,Alu
chr185742155GA0.00813BCL10,LOC646626+,-FALSE
chr725160004TC0.00915CYCS-TRUE
chr5149364145AG0.00383SLC26A2+TRUEAluSc8SINE,Alu
chr2242384528GT2.14488E-07FARP2+FALSEAluJrSINE,Alu
chr7299940GA8.49279E-08FAM20C+FALSE
chr1150937771TA0.00026CERS2-FALSE(ATTTTTT)nSINE,Alu
chr1990984GA0.00787AGRN+FALSE
chr153288894AG8.27269E-06ZYG11B+TRUEAluJoSINE,Alu
chr121780000GT0.00153NBPF3+FALSEERVL-E-intSINE,Alu
chr1623682631CT0.00960DCTN5+FALSE
chr76501833AT0.00032KDELR2-FALSE
chr1145512951AG4.65248E-05NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr133147934AG0.00251SYNC,RBBP4+,-FALSEAluSxSINE,Alu
chrX77083955TC0.00065MAGT1-TRUEAluSzSINE,Alu
chr4120219239TA0.00707C4orf3-FALSE
chr1179312752CT0.00106SOAT1+FALSE
chr1539879717GA0.00162THBS1+FALSE
chr261278030AG0.00218PEX13+TRUEAluYSINE,Alu
chr1327538AG0.00010.FALSE
chr3183899832CT1.28780E-06AP2M1+FALSE
chr1109474776AG0.00149GPSM2,CLCC1+,-FALSEAluSzSINE,Alu
chr110519787AT0.00037.FALSE(A)nSINE,Alu
chr3111732608GA2.81327E-08TAGLN3+FALSE
chr11431295TC3.55878E-05ATAD3B+FALSE

Differential Expression Gene Analysis