Dataset Overview
RBP
GRSF1
Knock-Method
shRNA
RBP Family
RRM_1
Biosample Name
HepG2
Tissue Type
Liver
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
ENCODE
Profile ID
ENCSR674KDQ
Platform
HiSeq
Pubmed ID
32252787
GRSF1 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of GRSF1
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A1BG
15.89
8.64
-0.78612
1.53636E-06
6.58564E-06
A1CF
30.66
16.5
-1.07257
1.24362E-30
4.56955E-29
AAAS
25.65
20.39
-0.56625
1.88156E-08
1.07410E-07
AACS
15.28
22.06
0.43792
7.40995E-06
2.85265E-05
AADAT
4.81
4.51
-0.32913
0.02929
0.05266
AAGAB
8.9
5.5
-0.87794
2.67882E-11
2.22262E-10
AAK1
2.42
4.03
0.73838
1.23839E-06
5.38148E-06
AAMDC
23.01
19.02
-0.38961
0.01044
0.02113
AAR2
19.98
25.77
0.24276
0.01030
0.02088
AARS
64.38
104.72
0.60820
2.13942E-08
1.21455E-07
Showing 1 to 10 of 8,111 entries
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Function Analysis of Target Genes of GRSF1
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A1CF
52622648_52622741_52619601_52619745_52623792_52623840
0.00748
-0.249
DataSet_01_69
View details
ABI1
27060003_27060018_27059173_27059274_27065993_27066170
0.00691
-0.042
DataSet_01_69
View details
ACSL4
108939372_108939425_108926364_108926895_108976367_108976531
0.00964
-0.087
DataSet_01_69
View details
ACSL4
108939372_108939425_108926364_108926781_108976367_108976531
0.00699
-0.106
DataSet_01_69
View details
ADRM1
60883423_60883526_60883038_60883234_60883710_60883918
0.00144
-0.085
DataSet_01_69
View details
AFP
74313178_74313393_74309067_74309161_74315051_74315184
0.00393
-0.013
DataSet_01_69
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AHCTF1
247007096_247007171_247005995_247006078_247012916_247014744
0.00001
-0.54
DataSet_01_69
View details
AHSG
186336285_186336426_186334975_186335139_186337645_186337729
0.00991
-0.499
DataSet_01_69
View details
AKR1C1
5008195_5008273_5005453_5005720_5009118_5010578
0.00014
-0.052
DataSet_01_69
View details
AKR1C1
5008201_5008273_5005640_5005720_5009118_5009235
0.00274
-0.027
DataSet_01_69
View details
Showing 1 to 10 of 251 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A2M
9264754_9264807_9264904_9265132_9262909_9262930
0.00000
-0.269
DataSet_01_69
View details
ACADVL
7125985_7126184_7126451_7126556_7125495_7125621
0.00966
0.097
DataSet_01_69
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ACIN1
23550956_23551045_23559730_23559842_23548755_23550018
0.00176
0.164
DataSet_01_69
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ACSL4
108926364_108926601_108939372_108939425_108925947_108926125
0.00000
-0.098
DataSet_01_69
View details
ACTN4
39200896_39200982_39201915_39202001_39200034_39200116
0.00171
-0.05
DataSet_01_69
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ACTR3
114670748_114670804_114684921_114685032_114647686_114647900
0.00000
-0.278
DataSet_01_69
View details
ADAM9
38940486_38940592_38948777_38948865_38940159_38940240
0.00001
0.146
DataSet_01_69
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ADD1
2910241_2910331_2916610_2916767_2909469_2909571
0.00010
-0.159
DataSet_01_69
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AHSA2
61408454_61408540_61410681_61410797_61406115_61406306
0.00000
0.044
DataSet_01_69
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AHSG
186334975_186335139_186337645_186337729_186334231_186334316
0.00000
-0.108
DataSet_01_69
View details
Showing 1 to 10 of 151 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AMICA1
118082944_118083184_118083121_118083184_118081201_118081427
0.00966
-0.086
DataSet_01_69
View details
BCL2L2-PABPN1
23793346_23793537_23793346_23793498_23794455_23794538
0.00021
0.124
DataSet_01_69
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C17orf76-AS1
16342640_16343017_16342640_16342728_16343498_16343567
0.00016
0.077
DataSet_01_69
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COLCA2
111169975_111170449_111169975_111170068_111171251_111171346
0.00602
-0.483
DataSet_01_69
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CTNND1
57529268_57529591_57529268_57529518_57561481_57561553
0.00867
0.087
DataSet_01_69
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CTTN
70253623_70253832_70253623_70253697_70255936_70256066
0.00006
0.122
DataSet_01_69
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DDX56
44612161_44612343_44612172_44612343_44611945_44612036
0.00414
-0.075
DataSet_01_69
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DEF8
90025421_90025639_90025421_90025563_90027338_90027503
0.00480
-0.15
DataSet_01_69
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EIF6
33872499_33872607_33872528_33872607_33872183_33872295
0.00641
-0.022
DataSet_01_69
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ENY2
110346552_110346703_110346552_110346631_110348356_110348433
0.00000
-0.124
DataSet_01_69
View details
Showing 1 to 10 of 25 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABCD4
74756729_74756885_74756729_74756821_74756993_74757155
0.00919
-0.073
DataSet_01_69
View details
ACOT8
44472165_44472411_44472165_44472360_44472901_44473059
0.00491
-0.076
DataSet_01_69
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ACTG1
79478213_79478829_79478213_79478652_79478928_79479168
0.00053
0.009
DataSet_01_69
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APOA2
161193139_161193247_161193139_161193215_161193384_161193418
0.00132
-0.029
DataSet_01_69
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ASNS
97483891_97484066_97483891_97483992_97484664_97484771
0.00560
-0.039
DataSet_01_69
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ATP6V1G2-DDX39B
31508258_31508343_31508258_31508311_31509726_31509925
0.00540
-0.14
DataSet_01_69
View details
AUP1
74754067_74754272_74754067_74754186_74754374_74754490
0.00000
-0.06
DataSet_01_69
View details
AUP1
74754067_74754279_74754067_74754186_74754374_74754490
0.00113
-0.028
DataSet_01_69
View details
BAG6
31611666_31611754_31611666_31611751_31611858_31611971
0.00174
0.098
DataSet_01_69
View details
BAG6
31611858_31612004_31611858_31611971_31612083_31612191
0.00499
0.225
DataSet_01_69
View details
Showing 1 to 10 of 41 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABCC3
48755104_48755580_48755104_48755304_48755453_48755580
0.00342
-0.228
DataSet_01_69
View details
ACADVL
7127131_7127388_7127131_7127194_7127286_7127388
0.00087
0.025
DataSet_01_69
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ACTB
5567911_5569031_5567911_5568350_5568791_5569031
0.00001
0.015
DataSet_01_69
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ACTB
5568791_5569294_5568791_5569031_5569165_5569294
0.00308
0.011
DataSet_01_69
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ACTG1
79477952_79478652_79477952_79478134_79478213_79478652
0.00116
0.01
DataSet_01_69
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ADRBK1
67048202_67048655_67048202_67048254_67048563_67048655
0.00629
-0.046
DataSet_01_69
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AL136419.6
24684757_24685003_24684757_24684868_24684942_24685003
0.00330
0.215
DataSet_01_69
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AP1G2
24032792_24033065_24032792_24032847_24032924_24033065
0.00618
0.022
DataSet_01_69
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ARL6IP4
123467015_123467455_123467015_123467085_123467166_123467455
0.00054
0.256
DataSet_01_69
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ATF4
39916568_39917676_39916568_39916756_39917358_39917676
0.00002
0.064
DataSet_01_69
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
169811639
G
C
0.00134
C1orf112
+
FALSE
chr1
214529320
T
G
0.00365
PTPN14
-
FALSE
AluJb
SINE,Alu
chr1
91990445
A
G
0.00784
CDC7
+
FALSE
LFSINE_Vert
SINE,Alu
chr1
1251841
T
C
0.00222
CPSF3L
-
TRUE
AluSq2
SINE,Alu
chr1
78603279
A
G
0.00089
GIPC2
+
FALSE
chr1
85742157
G
C
0.00514
BCL10,LOC646626
+,-
FALSE
chr1
45976268
G
A
0.00168
MMACHC
+
FALSE
chr1
160967857
T
C
0.00032
F11R
-
TRUE
AluSp
SINE,Alu
chr1
10043053
A
G
0.00042
NMNAT1
+
TRUE
AluSc
SINE,Alu
chr1
179326908
A
G
0.00037
SOAT1
+
TRUE
AluJo
SINE,Alu
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression