Dataset Overview
RBPPTBP1
Knock-MethodshRNA
RBP FamilyRRM_5
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR527IVX
PlatformHiSeq
Pubmed ID32252787

PTBP1 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of PTBP1
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of PTBP1


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr5130537223AG0.00044LYRM7+TRUEAluSpSINE,Alu
chr416040617CT0.00032PROM1-FALSE
chr187379493GA0.00353SEP15-FALSE
chr159124223GA0.00327MYSM1-FALSEMIR3SINE,Alu
chr3183533964TC2.38465E-05MAP6D1-FALSE
chr570248477TA0.00163SMN1,SMN2+FALSEL1MC5aSINE,Alu
chr133148213AG0.00080SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr1959095449AG6.25071E-06CENPBD1P1+TRUEAluJbSINE,Alu
chr349762662GT6.99764E-06IP6K1-FALSE
chr286365817AG0.00046PTCD3+FALSE
chr2178482698AG0.00408TTC30A-FALSE
chr2100899665GA0.00758LONRF2-FALSE
chr123636031TA0.00965HNRNPR-FALSE
chr484525973CG0.00148GPAT3+FALSE
chr120976078TC0.00344PINK1,PINK1-AS+,-FALSEAluSzSINE,Alu
chr2164466038CA0.00021FIGN-FALSE
chr1176176230GA0.00168RFWD2-FALSE
chr1779476999GT6.09622E-06ACTG1-FALSE
chr56748659TC0.00032PAPD7+FALSE
chr16585331TC0.00094NOL9-TRUEFAMSINE,Alu
chr16683578TC0.00497PHF13+FALSE
chr270452144TG0.00191TIA1-FALSE
chr1168220479AG0.00113.FALSEAluSz6SINE,Alu
chr1149582019AG0.00082LINC00623,LINC00869,LOC103091866+FALSE
chr146075719AG0.00461NASP+TRUEAluSx4SINE,Alu
chr133149496AG0.00308SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr1145281633CA0.00059NBPF20,NOTCH2NL+FALSE
chr1476671382AG0.00777GPATCH2L+TRUEAluJr4SINE,Alu
chr1423794554GA0.00966BCL2L2-PABPN1,PABPN1+FALSEA-richSINE,Alu
chr194351062TA0.00189GCLM-FALSE
chr237331119TC0.00122.FALSEAluSx1SINE,Alu
chr1774561213AG0.00241SNHG16+FALSE
chr358308214GA0.00113.FALSELTR49SINE,Alu
chr116893841CT0.00272NBPF1-FALSE
chr1114940211GT8.00129E-05TRIM33-FALSE(T)nSINE,Alu
chr348787118TC0.00359PRKAR2A-TRUEAluSx3SINE,Alu
chr3197612334AG0.00070.FALSEAluSpSINE,Alu
chr116722111CT0.00453SZRD1+FALSE(TTTT)nSINE,Alu
chr330735330GT0.00402TGFBR2+FALSE
chr1201846675CT0.00145IPO9+FALSE
chr1143915747GA0.00603.FALSE
chr1179326882AG1.03454E-05SOAT1+TRUEAluJoSINE,Alu
chr185785554CT0.00365DDAH1-FALSE
chr16283264TC0.00521ICMT-TRUEAluSx3SINE,Alu
chr1169101269TG0.00307ATP1B1+FALSE(T)nSINE,Alu
chr2128952006AG0.00076UGGT1+TRUEAluSx1SINE,Alu
chr274690039GA0.00412MOGS-FALSE
chr171684352TC0.00793SMYD4-TRUEAluSx1SINE,Alu
chr226616356AG0.00030EPT1+FALSE
chrX77083981TC0.00647MAGT1-TRUEAluSzSINE,Alu
chr1100657416CT0.00102DBT-FALSEAluJbSINE,Alu
chr135657874GC0.00738SFPQ-FALSE
chr197116159GT0.00368INSR-FALSE
chr1138156GT0.00177LOC729737-FALSE
chr2232576431TC0.00593PTMA+FALSE
chr153359181AG0.00699ZYG11A+TRUEAluSxSINE,Alu
chr237429626AG0.00028CEBPZOS,CEBPZ+,-FALSEAluSzSINE,Alu
chr7137561077CA0.00995CREB3L2-FALSE
chr149227052AT0.00020AGBL4,BEND5-FALSE
chr1159887904AT8.82173E-05TAGLN2-FALSE
chr146075171AC0.00140NASP+FALSEA-richSINE,Alu
chr128826118AG0.00023PHACTR4+TRUEAluJbSINE,Alu
chr145116985CT0.00318RNF220+FALSE
chr1245017464TA0.00624HNRNPU,SNORA100-FALSE
chr5139876355GA0.00815ANKHD1,ANKHD1-EIF4EBP3+FALSEGA-richSINE,Alu
chr127874481CA0.00046AHDC1-FALSE
chr4165998226TC0.00754TMEM192-TRUEAluSxSINE,Alu
chr3155660742AG0.00504.FALSEAluSzSINE,Alu
chr116932783GC0.00843NBPF1-FALSEL1MC2SINE,Alu
chr579277952AC0.00041MTX3-FALSE(AC)nSINE,Alu
chr2203430456TG0.00162BMPR2+FALSE
chr110520296TC0.00108.FALSEAluSxSINE,Alu
chr1779838088TC6.81311E-05.FALSEAluSxSINE,Alu
chr123519504TA3.21384E-05HTR1D-FALSE
chr1115313038GA0.00144SIKE1-FALSE
chr636894338AG0.00607C6orf89+FALSEGA-richSINE,Alu
chr13654747CA0.00691TP73-AS1-FALSE
chr1666765441GT4.44089E-16DYNC1LI2-FALSEL2cSINE,Alu
chr255462102AG0.00026RPS27A+FALSE
chr1175161849GT0.00030KIAA0040-FALSE
chr39848198GT0.00295ARPC4,ARPC4-TTLL3+FALSE(T)nSINE,Alu
chr1298942808AG0.00019TMPO+TRUEAluScSINE,Alu
chr1145688665TA0.00015NBPF20,NBPF10,RNF115+FALSE
chr543574976TC0.00613NNT-AS1-TRUEAluSq2SINE,Alu
chr220818517TC0.00748HS1BP3-FALSE
chr1212587320TC0.00023TMEM206-FALSE
chr237333924TC0.00298EIF2AK2-FALSEAluSzSINE,Alu
chr129508350CT0.00859SRSF4-FALSE(GGC)nSINE,Alu
chr1146649884TA0.00338PDIA3P1+FALSE
chr644417142AG0.00144CDC5L+TRUEFLAM_CSINE,Alu
chr271214819AT0.00346TEX261-FALSE
chr12109039869TC0.00795CORO1C-FALSE
chr153712727CT0.00313LRP8-FALSE
chr167874849TC7.36358E-05SERBP1-TRUEAluSxSINE,Alu
chr6160211656GT0.00339MRPL18+FALSE
chr1155695968AG0.00017DAP3+TRUEAluSpSINE,Alu
chr4128756737AG8.66859E-06.FALSEAluSxSINE,Alu
chr133148706AG0.00050SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr261416411TG0.00146USP34-FALSEAluSc8SINE,Alu
chr136032229AC0.00806NCDN+FALSE
chr1144874815TC0.00701NBPF20,PDE4DIP+,-FALSE
chr310193475AG0.00110VHL+TRUEAluJrSINE,Alu
chr133148721AG0.00359SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr1765335394TC5.10125E-06PSMD12-TRUEAluSxSINE,Alu
chr6150047370TC0.00084NUP43-TRUEAluScSINE,Alu
chr1657505662TG0.00332POLR2C+FALSE(GGTGGG)nSINE,Alu
chr1203822584TC5.41257E-07ZC3H11A+FALSE
chr125894467AT0.00136LDLRAP1+FALSEMIRbSINE,Alu
chr572801321TA0.00280BTF3+FALSE
chr1169101307CT0.00405ATP1B1+FALSE
chr136067833TC3.75622E-05PSMB2-TRUEAluSzSINE,Alu
chr1543767774GC0.00057TP53BP1-FALSE
chr1180247477CT0.00060.FALSE
chr116933740TA0.00286NBPF1-FALSEGA-richSINE,Alu
chr3183529603GA0.00219YEATS2+FALSE
chr19353122CG0.00562SPSB1+FALSE(GCG)nSINE,Alu
chr9132575836AC0.00546TOR1A-FALSE
chr44864940CT0.00247MSX1+FALSE
chr540832551AT0.00394RPL37-FALSE
chr1168218504TC0.00748.FALSEAluSzSINE,Alu
chr175288079AC0.00085RABEP1+FALSE
chr11662754TC0.00856SLC35E2-TRUEAluYSINE,Alu
chr1145284175GC0.00481NBPF20,NOTCH2NL+FALSE
chr575003678TC0.00435POC5-FALSE
chr5118175329TC2.47285E-05DTWD2-TRUEAluJrSINE,Alu
chr1475202645AG3.73418E-05FCF1+TRUEAluScSINE,Alu
chr3121382204CT0.00309GOLGB1-FALSE
chr1197125427TC0.00331ZBTB41-FALSE
chr133148287AG0.00052SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr717384354AG0.00908AHR+TRUEAluSxSINE,Alu
chr151822219GA0.00017EPS15-FALSE
chr7117832138GA0.00885LSM8+FALSE
chr3120128940AG0.00434FSTL1-FALSE
chr5141690772CT0.00632SPRY4-FALSE
chr2043706946AG0.00434STK4+TRUEAluSx4SINE,Alu
chr1953999034AG0.00282.FALSEAluSq2SINE,Alu
chr111084103TA0.00146TARDBP+FALSE
chr5172396725TA0.00014RPL26L1+FALSE
chr1167396055TA0.00031POU2F1+FALSE
chr643747963GC0.00274VEGFA+FALSE
chr1200375846GT0.00061ZNF281-FALSE(T)nSINE,Alu
chr2183817957TA0.00031NCKAP1-FALSE
chr1118411057TG0.00254GDAP2-FALSE
chr1228520973CG0.00875OBSCN+FALSE
chr12123253851AG0.00470DENR+FALSE(AT)nSINE,Alu
chr1155214017CA0.00261GBA-FALSEAluSx3SINE,Alu
chr1144816555CT0.00530NBPF20,NBPF9+FALSE
chr46677063GA0.00087LOC93622+FALSE
chr127202844TC0.00076.FALSEAluSq2SINE,Alu
chr116889639TC0.00745NBPF1-TRUE
chrX77083915TC0.00075MAGT1-TRUEAluSzSINE,Alu
chr729962665CT0.00059SCRN1-FALSE
chr138279987TC0.00980MTF1-FALSE
chr3195243006CA0.00982PPP1R2-FALSE
chr10104661031AG0.00265BORCS7-ASMT,AS3MT+TRUEAluYSINE,Alu
chr1144852203TG0.00029NBPF20,PDE4DIP+,-FALSE
chr146075791AG0.00120NASP+TRUEAluSx4SINE,Alu
chr1563988357CG0.00539HERC1-FALSE
chr131344952CT0.00842SDC3-FALSE
chr2201774600TC1.56082E-05.FALSEAluJr4SINE,Alu
chr5149823786CT0.00327.FALSE
chr3197400501CG0.00011RUBCN-FALSE
chr1949472GA2.93477E-10ISG15+FALSE
chrX123043142AG0.00045XIAP+TRUEAluSzSINE,Alu
chr11653093AG0.00642CDK11B,CDK11A-FALSEL2SINE,Alu
chr1153617980AG8.13079E-05CHTOP+FALSE
chr185718132CA0.00738C1orf52-FALSE
chr1110596904AG0.00364STRIP1+FALSE
chr2202029998TA0.00350CFLAR+FALSE(TTA)nSINE,Alu
chr16283260TC0.00054ICMT-TRUEAluSx3SINE,Alu
chr110517567TC9.16527E-06.FALSEAluSx1SINE,Alu
chr237230734CT0.00192HEATR5B-FALSE
chr1214524531TC0.00753PTPN14-TRUEAluSgSINE,Alu
chr258387000CT0.00027VRK2,FANCL+,-FALSE
chr3194373833GA0.00217LSG1-FALSE
chr577655392TC0.00080SCAMP1-AS1-TRUEAluSx4SINE,Alu
chr439550715TC0.00995UGDH-AS1,SMIM14+,-FALSEAluSx1SINE,Alu
chr110520378TC0.00895.FALSEAluSx1SINE,Alu
chr1942375624AG0.00339.FALSEAluSxSINE,Alu
chr187213190AC0.00054SH3GLB1+FALSE
chr171946503CG0.00154DPH1,OVCA2+FALSE
chr471859287CG0.00557DCK+FALSE
chr199673107TC1.71894E-07.FALSEAluSx3SINE,Alu
chr119542679TC0.00584LOC101927895,EMC1+,-FALSEFRAMSINE,Alu
chr16282587TC7.24363E-07ICMT-TRUE
chr119586520AG6.58771E-06MRTO4+TRUEAluSzSINE,Alu
chr838829839AG0.00184PLEKHA2+TRUEAluJr4SINE,Alu
chr476568676TA0.00051G3BP2-FALSE
chr111083183GT0.00342TARDBP+FALSE
chr4128756579AG0.00501.FALSEAluSxSINE,Alu
chr417802919TC0.00857DCAF16-TRUEAluSzSINE,Alu
chr116889820CT0.00012NBPF1-FALSE
chr133068435AG0.00081ZBTB8A+TRUEAluYSINE,Alu
chr128836975AG0.00782SNHG3,RCC1+TRUEAluScSINE,Alu
chr457801150AT0.00462REST+FALSE
chr314986104TC6.10128E-05FGD5-AS1-TRUEFLAM_CSINE,Alu
chr744917320TC0.00082PURB-TRUEAluSzSINE,Alu
chr1201939479TA0.00645TIMM17A+FALSE
chr534906547TC0.00051RAD1-TRUEAluJoSINE,Alu
chr197144886AG0.00078.FALSE
chr1420923558AC0.00373APEX1+FALSE
chr16713251AG0.00628WDR90+TRUEAluSxSINE,Alu
chr194352570GT0.00402GCLM-FALSEAluSx1SINE,Alu
chr1347345467GT0.00495ESD-FALSE
chr227293349CT0.00503AGBL5,OST4+,-FALSE
chr187379497AG0.00067SEP15-FALSE
chr11594196TC0.00097CDK11B,SLC35E2B-FALSE
chr13545189TG0.00027TPRG1L+FALSE
chrX16782947AG0.00225.FALSEAluJbSINE,Alu
chr174672323CA0.00616FPGT-TNNI3K,FPGT+FALSEX12_DNASINE,Alu
chr1327407AG3.55459E-07.FALSE
chr337407664GT1.42794E-05GOLGA4+FALSE
chr152520867TA0.00206TXNDC12-FALSE
chr765844562TC0.00695LINC00174-FALSE
chr7115898442GC2.36867E-05TES+FALSEAluSxSINE,Alu
chr1114449662TC0.00223DCLRE1B+FALSE
chr1145284883AG0.00329NBPF20,NOTCH2NL+FALSEL2aSINE,Alu
chr237430603TC0.00483CEBPZOS,CEBPZ+,-FALSE
chr110517456TC0.00722.FALSEAluSx1SINE,Alu
chr146751578TG0.00380LRRC41-FALSE
chr9136209399AT0.00011MED22-FALSE
chr121766776GC0.00343NBPF3+FALSE
chr1419684445AG0.00351DUXAP10+FALSE
chr123409538GA0.00292KDM1A+FALSE
chr1256215099TA0.00227DNAJC14-FALSE
chr146828460CT0.00101NSUN4+FALSE
chr310193796AG0.00493VHL+TRUEAluSxSINE,Alu
chr1100615003GA0.00046TRMT13,LRRC39+,-FALSE
chr9125609943AG0.00247.FALSE
chr5180001389GA0.00138CNOT6+FALSE
chr122418122TC0.00790CDC42+FALSE
chr1179326418AG0.00626SOAT1+TRUEAluSgSINE,Alu
chr398518155AT0.00777DCBLD2-FALSE
chr2206986949TC0.00693.FALSEAluJrSINE,Alu
chr6157405930GA0.00077ARID1B+FALSE
chr1950410816GT0.00050IL4I1,NUP62-FALSEAluSzSINE,Alu
chr237429626AG0.00385CEBPZOS,CEBPZ+,-FALSEAluSzSINE,Alu
chr111188109CA0.00817MTOR-FALSE
chr456295161TA0.00075CLOCK-FALSE(T)nSINE,Alu
chr1179829505TC0.00592TOR1AIP2-TRUEAluJrSINE,Alu
chr15102512797AG0.00080WASH3P+FALSE
chr111347155CT0.00273UBIAD1+FALSE
chr153288924AG1.39497E-05ZYG11B+TRUEAluJoSINE,Alu
chr119234134AG0.00027IFFO2-FALSE
chr1113240711GA0.00454MOV10+FALSE
chr1144619903TA0.00712NBPF20,NBPF9+FALSE
chr1761897188GT0.00465FTSJ3-FALSE
chr1145291108AC0.00827NBPF20+FALSE
chr153289759AG0.00383ZYG11B+TRUEAluSzSINE,Alu
chr1201350983CT0.00768LAD1-FALSE
chr794060361CT2.02320E-06COL1A2+FALSE
chr9131812176CT0.00220MIGA2+FALSE
chr12100562932GT0.00079GOLGA2P5-FALSEAluSgSINE,Alu
chr1150937961AC0.00060CERS2-FALSEG-richSINE,Alu
chr1161932324AG0.00056ATF6+FALSE
chr116892279CA0.00326NBPF1-FALSE
chr1563111739TC0.00914TLN2+FALSE
chr146662492GA9.93078E-05POMGNT1-FALSE
chr8117858600TA0.00015RAD21-FALSE
chr132661578CT0.00694TXLNA+FALSE(T)nSINE,Alu
chr1168523504TC0.00029CPT1A-TRUEAluSqSINE,Alu
chr1155403831AG0.00676ASH1L,POU5F1P4+,-FALSE
chr291805928TC0.00000.FALSEMLT1H1SINE,Alu
chr153288916AG0.00289ZYG11B+TRUEAluJoSINE,Alu
chr439550549TC0.00014UGDH-AS1,SMIM14+,-FALSEAluSx1SINE,Alu
chr1583826216CT0.00278HDGFRP3-FALSE(CTT)nSINE,Alu
chr189271574TC0.00074PKN2+FALSE
chr11209196CG0.00581UBE2J2-FALSE(CCG)nSINE,Alu
chr125169634AG0.00531CLIC4+FALSE
chr16282237TC0.00372ICMT-TRUEAluSzSINE,Alu
chr1186390303AC0.00455C1orf27+FALSEL1ME3FSINE,Alu
chr228636644AG0.00918FOSL2+FALSE
chr540715440AC0.00646TTC33-FALSE
chr1201846627AT0.00571IPO9+FALSE(CA)nSINE,Alu
chr1101444071GA0.00963SLC30A7+FALSEMIR3SINE,Alu
chr16283434TC4.87712E-06ICMT-TRUEAluSx3SINE,Alu
chr1148252049AC0.00493NBPF8,NBPF14,NBPF9-FALSE
chr136534830AG0.00470.FALSEAluJoSINE,Alu
chr613790931TC0.00122MCUR1-TRUEAluSx1SINE,Alu
chr126603883GA0.00088CEP85+FALSE
chr344790781TC0.00158KIAA1143-TRUEAluYSINE,Alu
chr128662053GA0.00158MED18+FALSEAluSq2SINE,Alu
chr1118066459AG0.00729MAN1A2+FALSE
chr1168220535AG0.00665.FALSEAluSz6SINE,Alu
chr1145826918GC0.00829NBPF20,NBPF10,GPR89A+,-FALSE
chr11668943AC0.00640SLC35E2-FALSE
chr2118940466AT0.00169CXADR+FALSEAluYSINE,Alu
chr7100279138AT0.00741GIGYF1-FALSEA-richSINE,Alu
chr190152146CT1.61967E-05LRRC8C+FALSE
chr178414329GA0.00922FUBP1-FALSEA-richSINE,Alu
chr76370194CT0.00029FAM220A-FALSE
chr2102508658TA0.00275MAP4K4+FALSE
chr1148003749TC0.00050NBPF8-TRUEL1MC4SINE,Alu
chr1061548859AC0.00011CCDC6-FALSE

Differential Expression Gene Analysis