Dataset Overview
RBPHNRNPC
Knock-MethodshRNA
RBP FamilyRRM_1
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR052IYH
PlatformHiSeq
Pubmed ID32252787

HNRNPC - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of HNRNPC
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of HNRNPC


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr274349080AG0.00094.FALSEAluSzSINE,Alu
chr1156565045CA0.00995GPATCH4-FALSE
chr250147867TA0.00896NRXN1-FALSE(GT)nSINE,Alu
chr4155457051AT0.00378PLRG1-FALSEL2d2SINE,Alu
chr76064007TA0.00551EIF2AK1-FALSE
chr116913612GA0.00145NBPF1-FALSE
chr1207942535AG0.00102CD46+TRUEAluSg4SINE,Alu
chr19643155AG0.00015.FALSEAluSxSINE,Alu
chr1139233CA0.00653LOC729737-FALSE
chr194351065AT0.00142GCLM-FALSE
chr1118165973CT3.23914E-05FAM46C+FALSE
chr4177241194CT6.44832E-08SPCS3+FALSE
chr115818065TC0.00372CASP9-TRUEAluJbSINE,Alu
chr417804847TC0.00512DCAF16-TRUEAluSxSINE,Alu
chr285772404CA0.00015GGCX-FALSE
chr3195963395AG0.00028.FALSE
chr1542860107AG0.00194HAUS2+TRUEAluSgSINE,Alu
chr144035352CT0.00055PTPRF+FALSE
chr14103941379CA0.00705MARK3+FALSE
chr1207943325AG0.00158CD46+TRUEAluSx1SINE,Alu
chr410443059AT0.00187ZNF518B-FALSE
chr247703548GA5.05442E-05MSH2+FALSE
chr110517653TC0.00256.FALSEAluSx1SINE,Alu
chr153289547AG0.00352ZYG11B+TRUEAluSzSINE,Alu
chr232535747AG0.00250.FALSEAluJbSINE,Alu
chr7112579815GT0.00997BMT2-FALSE(CGC)nSINE,Alu
chr4187647832CG0.00592.FALSE
chr2036147563TC0.00313BLCAP-TRUE
chr7152343700TC0.00061XRCC2-TRUEAluSx3SINE,Alu
chr657034845GA0.00581ZNF451,LOC101927211+,-FALSE
chr1229730452GA0.00236TAF5L-FALSE
chr1075009781TC9.15447E-06DNAJC9-AS1,MRPS16+,-FALSEAluYSINE,Alu
chr1075009921TC5.40286E-05DNAJC9-AS1,MRPS16+,-FALSEAluYSINE,Alu
chr1779476999GT6.09622E-06ACTG1-FALSE
chr624720534TC0.00053.FALSE
chr13545194CG0.00044TPRG1L+FALSE
chr1225706943CT0.00229ENAH-FALSE
chr320025661CT4.83976E-05RAB5A,PP2D1+,-FALSE
chr170904800GT0.00678CTH+FALSE
chr110520258TC0.00396.FALSEAluSxSINE,Alu
chr2206987108TC0.00015.FALSEAluSxSINE,Alu
chr738764395TC0.00139VPS41-TRUEAluSpSINE,Alu
chr413604418GC2.95746E-07BOD1L1-FALSE
chr299813015AG0.00235MRPL30+TRUEAluJbSINE,Alu
chr4185309401AG0.00782IRF2-FALSE
chr4178281754GA0.00057NEIL3+FALSE
chr1205737665GT0.00025RAB29-FALSEAluSq2SINE,Alu
chr679649800CG0.00864PHIP-FALSE
chr1156613632GA0.00187BCAN+FALSE
chrX123046306AG0.00016XIAP+TRUEAluJbSINE,Alu
chr11593828GC0.00348CDK11B,SLC35E2B-FALSE
chr1150783968TA0.00368ARNT-FALSE
chr224494638TG0.00507ITSN2-FALSE(TATCCT)nSINE,Alu
chr1220231338TC0.00762RNU5F-1,BPNT1+,-FALSEAluYSINE,Alu
chr176229185TA0.00280ACADM+FALSE
chr110517550TC0.00457.FALSEAluSx1SINE,Alu
chr116933623GA0.00789NBPF1-FALSEGA-richSINE,Alu
chr647594192CT0.00591CD2AP+FALSE
chr3121435624CT0.00063GOLGB1-FALSE
chr128662182AG0.00402MED18+TRUEAluSq2SINE,Alu
chr1145293566GA0.00103NBPF20,NBPF10+FALSE
chr298388811CG0.00123TMEM131-FALSE
chr237328027TC0.00026.FALSE
chr126143728CT0.00800SEPN1+FALSEAluSxSINE,Alu
chr19160963TC0.00354.FALSEAluJbSINE,Alu
chr1253936878GT0.00036ATF7-FALSE
chr11647871TC0.00906CDK11B,CDK11A-FALSE
chr1675479910TC0.00026TMEM170A-TRUEAluSg4SINE,Alu
chr3112299732AG0.00189SLC35A5+FALSE
chr19324670AG0.00734H6PD+FALSE
chr101086810TA0.00245IDI2-AS1,IDI1+,-FALSE
chr1675479891TC9.48885E-06TMEM170A-TRUEAluSg4SINE,Alu
chr1689623607AG0.00915SPG7+FALSE
chr153291395AG0.00323ZYG11B+TRUEAluJrSINE,Alu
chr152378211TC0.00195RAB3B-TRUEFLAM_CSINE,Alu
chr193121451CT0.00567GNA11+FALSE
chr116011005GC0.00616PLEKHM2+FALSE(GCG)nSINE,Alu
chr2218571457AG0.00493PEX26+TRUEAluSzSINE,Alu
chr8145159709CA0.00314MAF1+FALSE
chr111734730CT4.90909E-09MAD2L2-FALSE
chr2201676441GA0.00140LOC101927795,BZW1+,-FALSE
chr128087457GT0.00178FAM76A+FALSE(T)nSINE,Alu
chr1144930596CA0.00103NBPF20,PDE4DIP+,-FALSE
chr1629454768AG0.00564SMG1P6,BOLA2-SMG1P6-FALSE
chr145975574AG0.00613MMACHC+TRUEAluSx4SINE,Alu
chr145452227GC0.00126EIF2B3-FALSE
chr2202032184AG0.00954CFLAR+FALSEAluJoSINE,Alu
chr115989141CG0.00677.FALSE
chr145975669AG0.00695MMACHC+TRUEAluSx4SINE,Alu
chr1143189486AG0.00122LOC102723769-FALSE
chr119428086GT0.00449UBR4-FALSE
chr1610625406TC1.26372E-11EMP2-TRUEAluSxSINE,Alu
chr1144828857CG4.37583E-07NBPF20,NBPF9+FALSE
chr1154128835GT0.00032TPM3-FALSE
chr264863970CT9.52027E-09SERTAD2-FALSE
chr1542503333TC0.00120TMEM87A-FALSE(T)nSINE,Alu
chr399886662GA0.00011CMSS1+FALSE
chr237328008TC0.00733.FALSE
chr388101339TC0.00531CGGBP1-FALSE
chr6158093827CT0.00201ZDHHC14+FALSE
chr8144332082TC7.73207E-05ZFP41+FALSE
chr779848333TG0.00322GNAI1+FALSE
chr720177664TC0.00089MACC1,LOC101927668-TRUEAluSxSINE,Alu
chr127108139AT0.00683ARID1A+FALSE
chr127202835TC0.00094.FALSEAluSq2SINE,Alu
chr525415881TC0.00911.FALSE
chr126608019TA3.63623E-05.FALSE
chr112401868AC0.00526VPS13D+FALSE
chr153250625TC0.00178ZYG11B+FALSE
chr775677504CT0.00768MDH2+FALSE
chr42940125TC4.75438E-05NOP14-AS1,NOP14+,-FALSEAluSpSINE,Alu
chr9100777784TA0.00080ANP32B+FALSE
chr613790931TC0.00948MCUR1-TRUEAluSx1SINE,Alu
chr626095642AG0.00332.FALSEAluYSINE,Alu
chr110520819TC0.00034DFFA-TRUEAluSc8SINE,Alu
chr1117530273AG0.00270PTGFRN+FALSE
chr1762109CT0.00026LINC00115-FALSE
chr1773940888TC2.69053E-06ACOX1-TRUEAluSx1SINE,Alu
chr1118167524CT0.00902FAM46C+FALSE
chr166058513AG0.00091LEPR+FALSE
chr1207942427AG0.00822CD46+TRUEAluSg4SINE,Alu
chr364081236TC8.95068E-05PRICKLE2,PRICKLE2-AS1+,-FALSE
chr10121588038AC0.00100INPP5F+FALSE
chr457326329AG0.00077PAICS+TRUEAluJrSINE,Alu
chr211321880CT0.00064ROCK2-FALSEAluSx1SINE,Alu
chr23609064GA0.00212RNASEH1-AS1+FALSEMER33SINE,Alu
chr744841933AG0.00192PPIA+TRUEAluSxSINE,Alu
chr126604691GC0.00043CEP85+FALSE
chr189525966TC0.00039GBP1-FALSE
chr5125962344AG0.00101PHAX+TRUEAluScSINE,Alu
chr1179044212AG7.62870E-06FAM20B+TRUEAluSxSINE,Alu
chr19162234TC0.00896.FALSEAluSxSINE,Alu
chr110518688TC0.00341.FALSEAluSx1SINE,Alu
chr1157044418GC0.00707.FALSE
chr81730491AG5.38446E-06CLN8+TRUEAluSx1SINE,Alu
chr375779650GC0.00116ZNF717-FALSE
chr127731933CA1.77427E-09WASF2-FALSE
chr2101622886TA0.00705RPL31+FALSE
chr8144357975CT0.00444GLI4+FALSE
chr1142688597CT0.00605.FALSE
chr1610623705TC0.00011EMP2-TRUEAluSpSINE,Alu
chr5150869672AT0.00755SLC36A1+FALSE
chr124022909TA0.00177RPL11+FALSE
chr167874697TC0.00186SERBP1-TRUEAluSx3SINE,Alu
chr5151041883GA0.00343SPARC-FALSE
chr3195243002CA0.00358PPP1R2-FALSE
chr1145511962AG0.00187NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr1145369476AG0.00332NBPF20,NBPF10+FALSEL1MC4SINE,Alu
chr153359182AG0.00321ZYG11A+TRUEAluSxSINE,Alu
chr110521103TC0.00788DFFA-TRUEAluYSINE,Alu
chr119542310TC0.00510LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr119585772GA0.00576MRTO4+FALSEAluSc8SINE,Alu
chr261416406TG0.00010USP34-FALSEAluSc8SINE,Alu
chr133148045AG0.00264SYNC,RBBP4+,-FALSEAluSxSINE,Alu
chr135816903CT0.00174ZMYM4+FALSE
chr136529419AG0.00842.FALSEAluJrSINE,Alu
chr838829416AG0.00695PLEKHA2+TRUEAluYcSINE,Alu
chr348787640TC0.00320PRKAR2A-TRUEAluSpSINE,Alu
chr16282324TC0.00142ICMT-TRUEAluSzSINE,Alu
chr153291344AG0.00088ZYG11B+FALSE(A)nSINE,Alu
chr232539582AG0.00419.FALSEAluSpSINE,Alu
chr9130209956AT0.00221RPL12-FALSE
chr131532379AG0.00061PUM1-FALSE
chr19161011TC3.85416E-05.FALSEAluJbSINE,Alu
chr167896040GA1.31286E-05SERBP1-FALSE
chr1688789700CT0.00703PIEZO1-FALSE
chr12133635613TC0.00805.FALSE
chr2201774185TC0.00921.FALSEAluSzSINE,Alu
chr224225177AG0.00375.FALSEAluSxSINE,Alu
chr8144684445GA0.00062.FALSE
chr121602602AG8.31525E-05ERC1+FALSEAluSxSINE,Alu
chr116945409TA0.00105CROCCP2-FALSE
chr146076462AG1.23194E-07NASP+TRUEAluSxSINE,Alu
chr16582470TC0.00370NOL9-TRUEAluSx1SINE,Alu
chr19642828TA0.00148SLC25A33+FALSE
chr3179306775CT7.88487E-06MRPL47-FALSE
chr817503270GC0.00410MTUS1-FALSE
chr116133987TC0.00707UQCRHL-FALSE
chr124296856TG0.00564.FALSEAluSgSINE,Alu
chr5149829071TC0.00407RPS14-FALSE
chr21637531AG0.00664PXDN-FALSE
chr2128601490TC0.00013.FALSEAluJrSINE,Alu
chr236776056TA0.00030CRIM1+FALSE
chr1168218522AG0.00153.FALSEAluSzSINE,Alu
chr1583826212CT0.00278HDGFRP3-FALSE(CTT)nSINE,Alu
chr13545198TC3.01160E-05TPRG1L+FALSE
chr1155829140CG0.00889GON4L-FALSE
chr9108152702GA2.83018E-05SLC44A1+FALSE
chr140537923GA0.00609CAP1+FALSE(A)nSINE,Alu
chr163924020CT0.00945ITGB3BP-FALSE
chr119543457TC4.71011E-07LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr310168802AG6.92223E-05BRK1+FALSE
chr161411036AG0.00766GNPTG+TRUEAluSzSINE,Alu
chrX119572534CA0.00387LAMP2-FALSE
chr3128338880TA0.00828RPN1-FALSE
chr29629306GT0.00255ADAM17-FALSE
chr314986111TC0.00224FGD5-AS1-TRUEFLAM_CSINE,Alu
chr11344998AG0.00235.FALSEAluSgSINE,Alu
chr19643028AG0.00017.FALSEAluSxSINE,Alu
chr10121437033TG0.00357BAG3+FALSE
chr642855256AG0.00572RPL7L1+TRUEAluSpSINE,Alu
chr717384440AG0.00373AHR+TRUEAluSxSINE,Alu
chr119234134AG0.00027IFFO2-FALSE
chr1269237558AG0.00034MDM2+TRUE
chr179125148GA0.00203IFI44+FALSE
chr76501832AC0.00175KDELR2-FALSE
chr1214524566TC0.00040PTPN14-TRUEAluSgSINE,Alu
chr1153917621GC0.00020DENND4B-FALSE
chr393846831GA0.00547.FALSEAluSq2SINE,Alu
chr1168218574AG0.00898.FALSEAluSzSINE,Alu
chr332567573GA0.00320DYNC1LI1-FALSE(AT)nSINE,Alu
chr637138024GC0.00892PIM1+FALSE(GCA)nSINE,Alu
chr1190234133AC5.13910E-06BRINP3-FALSE
chr128825427AG0.00484PHACTR4+TRUEAluSgSINE,Alu
chr1246577921GT0.00306SLC38A1-FALSE
chr153288870AG3.51337E-08ZYG11B+TRUEAluJoSINE,Alu
chr1194801640AC0.00790SRSF8+FALSE
chr11245100CT0.00656PUSL1+FALSE
chr1572635829AC0.00054HEXA-FALSE
chr1431916792CT3.89824E-05LOC101927124,DTD2+,-FALSEAluSc8SINE,Alu
chr1142688511TC0.00089.FALSE
chr537291446TC6.87884E-05.FALSEAluSx3SINE,Alu
chr1161559407AG0.00376FCGR2C+FALSE
chr124286327GA0.00053PNRC2+FALSE
chr3183861750AC1.09807E-05EIF2B5+FALSE
chr237328075TC0.00863.FALSE
chr1780347528TC0.00048OGFOD3-TRUEAluJbSINE,Alu
chr1172411496AG0.00361C1orf105,PIGC+,-FALSE
chr2204162277AG0.00097CYP20A1+TRUEAluSxSINE,Alu
chr16283439TC0.00786ICMT-TRUEAluSx3SINE,Alu
chr466439443TC0.00593EPHA5-FALSE
chr291843429GA0.00037LOC654342-FALSE
chr1120694990CA0.00325.FALSEA-richSINE,Alu
chr358306666AG0.00139.FALSEAluSzSINE,Alu

Differential Expression Gene Analysis