Dataset Overview
RBPSRP68
Knock-MethodshRNA
RBP FamilyNon-canonical_RBP
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR167JPY
PlatformHiSeq
Pubmed ID32252787

SRP68 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of SRP68
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of SRP68


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr237329307TC0.00201.FALSEAluJr4SINE,Alu
chr110042955AG0.00430NMNAT1+TRUEAluScSINE,Alu
chr348556339GA6.87729E-06PFKFB4-FALSE
chr1220231276TC0.00545RNU5F-1,BPNT1+,-FALSEAluYSINE,Alu
chr5256514GC0.00198SDHA+FALSE
chr270452146TG0.00192TIA1-FALSE
chr136068369TC0.00404PSMB2-TRUEAluScSINE,Alu
chr393846831GA0.00547.FALSEAluSq2SINE,Alu
chr996438975TC0.00042PHF2+FALSE(CTCCAC)nSINE,Alu
chr264069566AG0.00075UGP2+FALSE
chr12125514120AG0.00232.FALSE(TA)nSINE,Alu
chr1210416438CA0.00085SERTAD4+FALSE
chr1939433141AG0.00224FBXO17-FALSEAluJbSINE,Alu
chr1475202372AG8.84130E-05FCF1+TRUEAluScSINE,Alu
chr1941097276CG0.00188SHKBP1+FALSE
chr119543353TC0.00101LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr2120980896TG0.00132TMEM185B-FALSE
chr1173457017CT0.00036PRDX6+FALSE
chr722984967AG0.00108FAM126A-FALSE
chr9133997543CG0.00046AIF1L+FALSE
chr114599TA0.00304WASH7P-FALSE
chr1257923211AC0.00071MBD6+FALSE(C)nSINE,Alu
chr1450053315GA0.00150.FALSE7SLRNASINE,Alu
chr11594196TC0.00097CDK11B,SLC35E2B-FALSE
chr136068243TC0.00217PSMB2-TRUEAluScSINE,Alu
chr358306797AG8.72021E-05.FALSEAluSzSINE,Alu
chr224225006AG0.00141.FALSEAluSxSINE,Alu
chr155060362GA0.00246ACOT11+FALSE
chr2203744241TC0.00511.FALSEAluSxSINE,Alu
chr29629290TG0.00180ADAM17-FALSE(TGT)nSINE,Alu
chr1114940227TC0.00852TRIM33-FALSE(T)nSINE,Alu
chr3179506721GC0.00018USP13+FALSE
chr2201842323TC0.00591FAM126B-TRUEAluJbSINE,Alu
chrX123046598AG0.00371XIAP+TRUEAluSzSINE,Alu
chr2127826533AG0.00942BIN1-FALSE
chr136067817TC0.00016PSMB2-TRUEAluSzSINE,Alu
chr110520672TC0.00222DFFA-TRUEAluSc8SINE,Alu
chr1450053348GA0.00067.FALSE7SLRNASINE,Alu
chr299812843AG0.00966MRPL30+TRUEAluJbSINE,Alu
chr19161231TC5.02708E-05.FALSEAluSxSINE,Alu
chr1474526984TC0.00496BBOF1,ALDH6A1+,-FALSEAluJoSINE,Alu
chr11447756GC0.00354ATAD3A+FALSE
chr348787042TC1.97898E-05PRKAR2A-TRUEAluSx3SINE,Alu
chr132096265AG0.00208PEF1-FALSE
chr261764920CA0.00363XPO1-FALSE
chr2206987635TC0.00930.FALSEAluJbSINE,Alu
chr1167765170GT0.00185UNC93B1-FALSE
chr189447839CG0.00488KYAT3,RBMXL1-FALSE
chr2239259540GA0.00493CBX6-FALSE
chr119543783TC0.00822LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr1565442602TC8.94083E-05CLPX-TRUEAluSg4SINE,Alu
chr12133298121AG1.85542E-11PGAM5+TRUEAluJoSINE,Alu
chr3185646406AT0.00023TRA2B-FALSE
chr16282255TC0.00954ICMT-TRUEAluSzSINE,Alu
chr136770601GT0.00055THRAP3+FALSE(T)nSINE,Alu
chr270316226AC0.00426PCBP1+FALSE
chr110521260TC0.00658DFFA-TRUEAluYSINE,Alu
chr4128756737AG8.66859E-06.FALSEAluSxSINE,Alu
chr145244419TA0.00027.FALSE
chr1226333561AG0.00373ACBD3-FALSE
chr6114178851TC0.00056MARCKS+FALSE(TGCCGC)nSINE,Alu
chr110519048TC0.00637.FALSEAluSx3SINE,Alu
chr634254565AT0.00617.FALSE(A)nSINE,Alu
chr4177252326AG0.00554SPCS3+TRUE
chr1749042394TC0.00015SPAG9-TRUEAluJbSINE,Alu
chr116933638GA4.07227E-05NBPF1-FALSEGA-richSINE,Alu
chr1111682307GC5.71833E-05DRAM2,CEPT1+,-FALSE
chr125688276AG0.00187TMEM50A+FALSE
chr6160526548CA0.00086IGF2R+FALSE
chr3195963397GA0.00037.FALSE
chr147099235AC0.00919.FALSE
chr3194125524CT0.00271ATP13A3-FALSE
chr237327676TC0.00462.FALSE
chr1207247478CT0.00995PFKFB2+FALSEMER5BSINE,Alu
chr3156259348GA0.00899SSR3-FALSEAluSq2SINE,Alu
chr110519982TC0.00417.FALSEAluJrSINE,Alu
chr1246714587GA0.00023TFB2M-FALSE
chr3197399402TC0.00840RUBCN-FALSE
chr9133778117CT0.00739FIBCD1-FALSE
chr791630345GA0.00473AKAP9+FALSE
chr1958357268AG0.00099ZNF587B+TRUEAluSx3SINE,Alu
chr224225509AG0.00132.FALSEAluSq2SINE,Alu
chrX77084001TC1.05736E-07MAGT1-TRUEAluSzSINE,Alu
chr178414329GA0.00785FUBP1-FALSEA-richSINE,Alu
chr2131906031CT0.00374PLEKHB2+FALSE
chr135319605AC0.00226SMIM12-FALSEAluSgSINE,Alu
chr6170887693GC0.00045PDCD2-FALSE
chr799017241CA0.00721PTCD1,ATP5J2-PTCD1-FALSE
chr3137787047CT0.00735DZIP1L-FALSE
chr1220232143TC7.81076E-05RNU5F-1,BPNT1+,-FALSEAluSzSINE,Alu
chr72274209TC0.00578MRM2-FALSEAluJrSINE,Alu
chr11252309AT0.00403CPSF3L-FALSEAluSxSINE,Alu
chr129519712TC0.00017MECR-TRUEAluJbSINE,Alu
chr192862896AG6.86172E-05.FALSEAluJrSINE,Alu
chr146164493TC0.00977IPP-TRUEAluJbSINE,Alu
chr174672474GA0.00014FPGT-TNNI3K,FPGT+FALSEX12_DNASINE,Alu
chr19663444CT0.00140TMEM201+FALSE
chr110519946TC0.00578.FALSEAluJrSINE,Alu
chr193616202TC0.00194TMED5-FALSE
chr1741144581AC0.00806RUNDC1+FALSEAluSxSINE,Alu
chr12133298417AG6.66134E-16PGAM5+TRUEAluSpSINE,Alu
chr439551087TC0.00263UGDH-AS1,SMIM14+,-FALSEAluSzSINE,Alu
chr159122059GA0.00476MYSM1-FALSE
chr1145283718GA0.00989NBPF20,NOTCH2NL+FALSE
chr1619715588TC0.00063.FALSEAluSgSINE,Alu
chr170718273AT0.00256.FALSE
chr68014786TC0.00086BLOC1S5-TXNDC5,BLOC1S5,EEF1E1-BLOC1S5-TRUEAluSzSINE,Alu
chr1145283980CT0.00113NBPF20,NOTCH2NL+FALSE
chr110517659TC0.00679.FALSEAluSx1SINE,Alu
chr273339708GA0.00991RAB11FIP5-FALSE
chr1148004525CT0.00541NBPF8-FALSE
chr186117191TC1.34616E-06ZNHIT6-TRUEAluSgSINE,Alu
chr1205583612CA0.00311ELK4-FALSE
chr537290554TC0.00010.FALSEAluSzSINE,Alu
chr1153907287GC0.00122DENND4B-FALSE(CTG)nSINE,Alu
chr1179042482AG0.00301FAM20B+TRUEAluSx1SINE,Alu
chr5112350098CT7.36383E-05DCP2+FALSE
chr152253793CT0.00966OSBPL9+FALSE
chr110042987AG0.00199NMNAT1+TRUEAluScSINE,Alu
chr110519119TC0.00892.FALSEAluSx3SINE,Alu
chr145976268GA0.00168MMACHC+FALSE
chr127202812TC0.00353.FALSEAluSq2SINE,Alu
chr642045563AG4.21139E-05TAF8+TRUEAluSzSINE,Alu
chr1220231997TC0.00244RNU5F-1,BPNT1+,-FALSEAluSzSINE,Alu
chr153288924AG0.00099ZYG11B+TRUEAluJoSINE,Alu
chr2217366195CA0.00929.FALSE
chr1145283718GA0.00897NBPF20,NOTCH2NL+FALSE
chr314986447TC2.03372E-08FGD5-AS1-TRUEAluSq2SINE,Alu
chr286251114TC0.00150.FALSEAluSxSINE,Alu
chr1773886249TC0.00069TRIM65-TRUEFRAMSINE,Alu
chr1204520000AG0.00032MDM4+TRUECharlie2aSINE,Alu
chr123636278AT0.00121HNRNPR-FALSE
chr124862649AG0.00074RCAN3+FALSE
chr136529575AG2.40551E-05.FALSEAluJrSINE,Alu
chr3191114266TC0.00258CCDC50+FALSE
chr159142713TC0.00246MYSM1-FALSE
chr572801321TA0.00427BTF3+FALSE
chr1165179817TC0.00599FRMD8+FALSE
chr1075009722TC0.00555DNAJC9-AS1,MRPS16+,-FALSEAluYSINE,Alu
chr7158536267TC0.00298ESYT2-FALSE
chr153288870AG0.00184ZYG11B+TRUEAluJoSINE,Alu
chr1298942886AG1.80851E-07TMPO+TRUEAluScSINE,Alu
chr375779650GC0.00116ZNF717-FALSE
chr1116235179GT0.00187VANGL1+FALSE
chr153289686AG0.00265ZYG11B+TRUEAluSzSINE,Alu
chr2025428547AG7.92315E-05GINS1+TRUEAluJbSINE,Alu
chr375779644CA0.00177ZNF717-FALSE
chr1149943157GA0.00060OTUD7B-FALSE
chr3183976477CT0.00215ECE2+FALSE
chr6109001952AG0.00978FOXO3+FALSE(A)nSINE,Alu
chr5175802154CT0.00883.FALSE(CATC)nSINE,Alu
chr1156613401TC5.47226E-05BCAN+FALSE
chr1200521412GA0.00292KIF14-FALSE
chr3195243003AC0.00301PPP1R2-FALSE
chr386991597TG0.00481VGLL3-FALSE
chr2234438139AG0.00220USP40-FALSE
chr1204520409AG0.00504MDM4+TRUEAluJbSINE,Alu
chr237329214TC0.00081.FALSEAluJr4SINE,Alu
chr540982394CT0.00037C7+FALSEAluSx1SINE,Alu
chr133148196AG0.00756SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr3196293764GC0.00392WDR53-FALSE
chr161411034AG0.00322GNPTG+TRUEAluSzSINE,Alu
chr827661037AT0.00314ESCO2+FALSEA-richSINE,Alu
chr1167782827GA0.00163ALDH3B1+FALSE
chr314986098TC0.00000FGD5-AS1-TRUEFLAM_CSINE,Alu
chr312641718GA0.00091RAF1-FALSE
chr139471000GA0.00518AKIRIN1+FALSE
chr2118854086GC0.00066INSIG2+FALSE
chr117345245CT0.00812SDHB-FALSE
chr743679092GC1.19724E-06COA1-FALSE
chr1145512024AG0.00392NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr296934504TC0.00021CIAO1+FALSE
chr18691521TC0.00150ENOSF1-TRUEAluJrSINE,Alu
chr11309885AG0.00010AURKAIP1-FALSE
chr438946481AG0.00168FAM114A1+FALSEMER1BSINE,Alu
chr119810692AC0.00069CAPZB-FALSE
chr357611237AG9.49839E-05DENND6A,PDE12+,-FALSE
chr174574751TA0.00246PELP1-FALSE
chr127662235GT0.00766TMEM222+FALSE
chr291847976CT0.00010.FALSETAR1SINE,Alu
chr19353122CG0.00562SPSB1+FALSE(GCG)nSINE,Alu
chr657034845GA0.00581ZNF451,LOC101927211+,-FALSE
chr3195963500CT0.00014.FALSE
chr153289940AG0.00245ZYG11B+TRUEFRAMSINE,Alu
chr204680094CT0.00438PRNP+FALSE
chr152498140GA0.00044TXNDC12,KTI12-FALSE
chr473922981TC0.00491COX18-TRUEAluSzSINE,Alu
chr2221304408AG0.00967CRKL+FALSE
chr143391826GT0.00202SLC2A1-FALSE
chr3179117242TC0.00011GNB4-TRUEAluSzSINE,Alu
chr5177577353CA0.00121NHP2-FALSE
chr190497768AG4.54321E-06ZNF326+TRUE
chr1113672640AG0.00629.FALSEAluJbSINE,Alu
chr11344893AG0.00186.FALSEAluSgSINE,Alu
chr340578997AG0.00094ZNF621+TRUEAluJrSINE,Alu
chr1079800439AT0.00380RPS24+FALSE
chr18938808CA0.00030ENO1-FALSE
chr3195694448CT0.00025SDHAP1-FALSE
chr154571374AG0.00280TCEANC2+TRUEAluScSINE,Alu
chr1298942643AG3.59360E-06TMPO+TRUEAluScSINE,Alu
chr1292537702TA0.00368BTG1-FALSE
chr136068231TC0.00022PSMB2-TRUEAluScSINE,Alu
chr352288956AT0.00042WDR82-FALSE
chr556177846GC0.00952MAP3K1+FALSE
chr167874697TC0.00022SERBP1-TRUEAluSx3SINE,Alu
chr119543459TC0.00540LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr145975266AG0.00188MMACHC+TRUEAluSg7SINE,Alu
chr110520099TC0.00152.FALSEAluSxSINE,Alu
chr16314743CT0.00615GPR153-FALSE
chr1118066724AT0.00979MAN1A2+FALSE
chr11234671GA0.00100ACAP3-FALSE
chr3149237753GA2.17555E-05WWTR1-FALSEAluSq2SINE,Alu
chr42070260GA0.00724NAT8L+FALSE(TG)nSINE,Alu
chr193299394AG0.00655FAM69A,RPL5+,-FALSE
chr11593060TC5.25946E-05CDK11B,SLC35E2B-FALSE
chr7130629624TC0.00568LINC-PINT-TRUE
chr2202901910GA0.00963FZD7+FALSE
chr7120740103GT0.00601CPED1+FALSE
chr1161488401TA0.00622FCGR2A+FALSE
chr3160213318TG0.00215KPNA4-FALSE
chr116893813AG0.00385NBPF1-FALSE
chr1101444069CA0.00962SLC30A7+FALSEMIR3SINE,Alu
chr631324643GC5.95617E-06.FALSE
chr2101893247CA0.00237RNF149-FALSE(A)nSINE,Alu
chr744841489AG0.00015PPIA+TRUEAluJrSINE,Alu
chr113716835CT0.00828NUP98-FALSE
chr573932315TC0.00420ENC1-FALSE
chr225044957GA0.00651CENPO,ADCY3+,-FALSE
chr1115249239GA0.00034NRAS-FALSE
chr128826023AG0.00342PHACTR4+FALSEAluJbSINE,Alu
chr128060574AG0.00206FAM76A+FALSE
chr1953155567TC0.00137ZNF83-TRUEAluSgSINE,Alu
chr232535568AG0.00192.FALSEMER8SINE,Alu
chr5151041873AG0.00136SPARC-FALSE
chr1148189152AC0.00050PTPRJ+FALSE
chr2105881486AG0.00042TGFBRAP1-FALSE
chr2128601583TC0.00550.FALSEAluJrSINE,Alu
chr122852880GC0.00247ZBTB40+FALSE
chr19160975TC0.00347.FALSEAluJbSINE,Alu
chr5125961534AG0.00233PHAX+TRUEAluSz6SINE,Alu
chr19163290TC0.00016.FALSEAluSpSINE,Alu
chr468484330GA0.00131UBA6-FALSE
chr152824084GA0.00207CC2D1B-FALSE
chr6107113955AG0.00265QRSL1+TRUEAluSgSINE,Alu
chr1912742290AG0.00564.FALSEAluSxSINE,Alu
chr1109465167TA0.00233GPSM2+FALSE
chr1144595935GA0.00061NBPF20+FALSEAluJbSINE,Alu
chr128836900AG0.00018SNHG3,RCC1+TRUEAluScSINE,Alu
chr136068369TC0.00252PSMB2-TRUEAluScSINE,Alu
chr2128603119TC0.00340.FALSEAluSpSINE,Alu
chr140923019GA0.00019ZFP69B+FALSE
chr439552022TC0.00015UGDH-AS1,SMIM14+,-FALSEAluSxSINE,Alu
chr9137330713TG0.00021RXRA+FALSE
chr1120163247TC0.00010ZNF697-FALSE
chr23592638TC0.00164RNASEH1-TRUEAluSz6SINE,Alu
chr5122165503AT0.00170SNX2+FALSE(AC)nSINE,Alu
chr145975498AG0.00064MMACHC+TRUEAluSx4SINE,Alu
chr237329300TC0.00590.FALSEAluJr4SINE,Alu
chr1118472382GT0.00029WDR3+FALSE
chr12434523TC0.00064PLCH2+FALSE
chr110318652CG0.00047KIF1B+FALSE
chr1201846627AT0.00571IPO9+FALSE(CA)nSINE,Alu
chr1173834225TC0.00105GAS5-FALSEAluSzSINE,Alu
chr1953914411AG8.16883E-05ZNF765+TRUEAluSxSINE,Alu
chr124296874GA0.00627.FALSEAluSgSINE,Alu
chr154493259TC0.00203TMEM59-TRUEAluSz6SINE,Alu
chr340503562GA0.00017RPL14+FALSE
chr720177664TC0.00089MACC1,LOC101927668-TRUEAluSxSINE,Alu
chr1615794312CT0.00796NDE1+FALSEAluSzSINE,Alu
chr1541590978AG1.05775E-06OIP5-AS1+TRUEAluSx1SINE,Alu
chr1160967899TC0.00011F11R-TRUEAluSpSINE,Alu
chr165298625GA0.00761RAVER2+FALSEX12_DNASINE,Alu
chr1945406537TC0.00278TOMM40+FALSE
chr1169101307CT0.00405ATP1B1+FALSE
chr3124948049TC0.00069ZNF148-TRUE
chr1761502459TA0.00161TANC2+FALSE
chr128087457GT0.00178FAM76A+FALSE(T)nSINE,Alu
chr255516897AG1.06852E-06CCDC88A-FALSE(GA)nSINE,Alu
chr1226259443CA0.00927H3F3AP4,H3F3A+FALSE
chr1144053663AT0.00155.FALSE
chr127202845TC0.00034.FALSEAluSq2SINE,Alu
chr11647814TC8.49337E-05CDK11B,CDK11A-FALSE
chr1100490275AG0.00142SLC35A3+TRUEAluSc5SINE,Alu
chr117313654CT0.00886ATP13A2-FALSE
chr7299881AG1.23967E-06FAM20C+FALSE
chr3155660961AG6.62819E-05.FALSEAluSzSINE,Alu
chr1206635246AT0.00283SRGAP2+FALSE(AC)nSINE,Alu

Differential Expression Gene Analysis