Dataset Overview
RBP
SFPQ
Knock-Method
shRNA
RBP Family
RRM_1
Biosample Name
HepG2
Tissue Type
Liver
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
ENCODE
Profile ID
ENCSR782MXN
Platform
HiSeq
Pubmed ID
32252787
SFPQ - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of SFPQ
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A1BG
11.1
5.0
-1.38363
2.51728E-08
3.66768E-07
A1CF
47.59
17.96
-1.09913
6.78197E-14
2.39709E-12
A2M
3527.82
3372.86
-0.65405
1.99721E-05
0.00014
AADAT
9.24
15.48
0.77901
2.02978E-05
0.00014
AAED1
4.75
4.08
-0.51344
0.03827
0.08850
AAGAB
10.36
12.43
0.37397
0.03591
0.08408
AAK1
4.32
9.1
1.19076
6.75409E-09
1.09072E-07
AARS2
4.14
6.87
0.70336
0.00124
0.00506
AARSD1
11.63
18.18
0.87525
0.00330
0.01162
AATF
20.53
35.68
0.85655
6.74624E-08
8.91768E-07
Showing 1 to 10 of 5,958 entries
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Function Analysis of Target Genes of SFPQ
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABLIM1
116213137_116213242_116211382_116211430_116225456_116225586
0.00069
0.04
DataSet_01_93
View details
ADH6
100134762_100134904_100131571_100131659_100137317_100137419
0.00279
-0.085
DataSet_01_93
View details
AFP
74310709_74310839_74309063_74309161_74315051_74315184
0.00000
0.019
DataSet_01_93
View details
AFP
74320952_74321007_74319481_74319614_74321347_74321891
0.00000
-0.012
DataSet_01_93
View details
AHSA2
61410681_61410797_61408472_61408540_61411846_61411935
0.00164
0.073
DataSet_01_93
View details
AHSG
186337645_186337702_186336285_186336426_186338374_186339089
0.00000
0.024
DataSet_01_93
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AHSG
186336079_186336280_186334975_186335139_186338374_186339089
0.00011
-0.205
DataSet_01_93
View details
AHSG
186336079_186336177_186334975_186335139_186336324_186336426
0.00490
-0.008
DataSet_01_93
View details
AKAP8L
15509440_15509514_15508524_15508666_15510112_15510221
0.00461
0.129
DataSet_01_93
View details
AKAP8L
15509440_15509577_15508524_15508666_15510112_15510221
0.00502
0.15
DataSet_01_93
View details
Showing 1 to 10 of 245 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A2M
9229941_9230016_9230296_9230453_9229351_9229532
0.00000
0.126
DataSet_01_93
View details
ABI1
27065993_27066170_27112066_27112234_27059173_27059274
0.00017
-0.18
DataSet_01_93
View details
ABLIM1
116227939_116227975_116232735_116232891_116225456_116225586
0.00145
-0.126
DataSet_01_93
View details
ACAP3
1229781_1230008_1230097_1230196_1229469_1229579
0.00017
-0.264
DataSet_01_93
View details
ACAT1
108005868_108005969_108009624_108009768_108004947_108005043
0.00003
0.254
DataSet_01_93
View details
ADD1
2910241_2910331_2916610_2916767_2909469_2909571
0.00188
0.084
DataSet_01_93
View details
AFG3L2
12337339_12337534_12340199_12340400_12328942_12329782
0.00830
-0.111
DataSet_01_93
View details
AFP
74310709_74310839_74313330_74313393_74309063_74309161
0.00000
0.283
DataSet_01_93
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ALDH7A1
125891622_125891707_125894931_125895026_125889978_125890085
0.00000
-0.133
DataSet_01_93
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ALG8
77820487_77820627_77824931_77825035_77817852_77817992
0.00000
-0.356
DataSet_01_93
View details
Showing 1 to 10 of 206 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AKAP8L
15509440_15510221_15510112_15510221_15508524_15508666
0.00274
0.135
DataSet_01_93
View details
ATG4B
242610742_242610966_242610742_242610820_242611605_242612007
0.00133
0.108
DataSet_01_93
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ATP5J2-PTCD1
99063733_99063787_99063751_99063787_99057708_99057816
0.00021
0.106
DataSet_01_93
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C11orf74
36616050_36616275_36616050_36616142_36631630_36631789
0.00701
0.383
DataSet_01_93
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CALD1
134617738_134618828_134617738_134618141_134625842_134625988
0.00035
-0.027
DataSet_01_93
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DDX47
12976136_12976334_12976136_12976253_12976803_12976950
0.00621
-0.045
DataSet_01_93
View details
FBXO38
147807185_147807384_147807185_147807285_147812986_147813087
0.00423
0.293
DataSet_01_93
View details
HEXA
72646031_72647965_72647899_72647965_72645408_72645519
0.00683
-0.085
DataSet_01_93
View details
HNRNPC
21699116_21699231_21699155_21699231_21698477_21698525
0.00040
-0.083
DataSet_01_93
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MAPK3
30128942_30129105_30128990_30129105_30128514_30128606
0.00444
0.122
DataSet_01_93
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Showing 1 to 10 of 25 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABLIM1
116207638_116207785_116207638_116207779_116211382_116211430
0.00774
-0.191
DataSet_01_93
View details
ACAD11
132297639_132297900_132297639_132297725_132298335_132298402
0.00717
-0.188
DataSet_01_93
View details
ACSL4
108926364_108926604_108926364_108926601_108939372_108939425
0.00000
-0.378
DataSet_01_93
View details
AHSG
186338374_186339107_186338883_186339107_186336285_186336426
0.00135
-0.083
DataSet_01_93
View details
C17orf76-AS1
16342841_16343017_16342973_16343017_16342640_16342728
0.00481
0.073
DataSet_01_93
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CDK8
26975602_26975761_26975605_26975761_26975405_26975484
0.00859
0.191
DataSet_01_93
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CENPQ
49456303_49456397_49456319_49456397_49456064_49456184
0.00655
0.233
DataSet_01_93
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CHD8
21859621_21859801_21859621_21859660_21859991_21860105
0.00732
-0.115
DataSet_01_93
View details
CSE1L
47712712_47713489_47712885_47713489_47711268_47711500
0.00428
0.046
DataSet_01_93
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DDX5
62496792_62497000_62496792_62496891_62498127_62498187
0.00000
-0.086
DataSet_01_93
View details
Showing 1 to 10 of 37 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACAD11
132297639_132298402_132297639_132297725_132298335_132298402
0.00510
-0.191
DataSet_01_93
View details
ACTG1
79477952_79478652_79477952_79478134_79478213_79478652
0.00481
0.008
DataSet_01_93
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ATG9A
220081085_220081554_220081085_220081187_220081373_220081554
0.00091
0.134
DataSet_01_93
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CFB
31918062_31918549_31918062_31918180_31918395_31918549
0.00604
-0.014
DataSet_01_93
View details
DDX5
62498279_62498667_62498279_62498341_62498556_62498667
0.00578
-0.013
DataSet_01_93
View details
DDX5
62496666_62498187_62496666_62496891_62498127_62498187
0.00988
-0.049
DataSet_01_93
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DRG2
18002946_18003749_18002946_18003037_18003676_18003749
0.00109
-0.131
DataSet_01_93
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EIF6
33871978_33872295_33871978_33872064_33872183_33872295
0.00864
-0.01
DataSet_01_93
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ERBB3
56487882_56488340_56487882_56487973_56488185_56488340
0.00014
-0.088
DataSet_01_93
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FTH1
61734783_61735103_61734783_61734843_61734929_61735103
0.00003
0.055
DataSet_01_93
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
11083183
G
T
0.00342
TARDBP
+
FALSE
chr1
70718273
A
T
0.00256
.
FALSE
chr1
92862896
A
G
6.86172E-05
.
FALSE
AluJr
SINE,Alu
chr1
36068295
T
C
0.00057
PSMB2
-
TRUE
AluSc
SINE,Alu
chr1
28865500
T
A
0.00509
RCC1
+
FALSE
chr1
28661633
A
G
0.00053
MED18
+
TRUE
AluSg
SINE,Alu
chr1
44818528
T
G
0.00486
ERI3
-
FALSE
chr1
16890639
C
T
0.00095
NBPF1
-
FALSE
chr1
169101270
T
G
0.00036
ATP1B1
+
FALSE
(T)n
SINE,Alu
chr1
165370475
G
C
0.00256
RXRG
-
FALSE
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression