Dataset Overview
RBP
LIN28B
Knock-Method
shRNA
RBP Family
CSD
Biosample Name
HepG2
Tissue Type
Liver
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
ENCODE
Profile ID
ENCSR927SLP
Platform
HiSeq
Pubmed ID
32252787
LIN28B - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of LIN28B
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A1BG
8.64
17.12
0.89817
1.72180E-11
4.69781E-10
A1CF
29.82
22.88
-0.19675
0.01299
0.03983
AAMDC
20.94
30.31
0.45729
0.00150
0.00690
AAMP
132.44
138.03
0.18207
0.01693
0.04927
AAR2
20.83
25.34
0.22442
0.00743
0.02545
AARS
50.74
67.35
0.31708
0.00076
0.00395
ABAT
27.42
32.69
0.24384
0.00084
0.00426
ABCA1
19.68
17.32
-0.22889
0.00183
0.00813
ABCA11P
3.52
4.79
0.45764
0.00714
0.02465
ABCA2
15.39
11.18
-0.39865
2.29551E-05
0.00019
Showing 1 to 10 of 5,714 entries
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Function Analysis of Target Genes of LIN28B
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AAR2
34824803_34824959_34824386_34824425_34827742_34828547
0.00638
-0.107
DataSet_01_98
View details
ABCC2
101556540_101556615_101554169_101554225_101556853_101557853
0.00667
0.084
DataSet_01_98
View details
ABCC3
48746213_48746280_48745790_48745878_48746500_48746627
0.00403
-0.228
DataSet_01_98
View details
ABCC6
16249648_16249711_16248729_16248888_16251519_16251666
0.00652
0.232
DataSet_01_98
View details
ABCC6P1
18585641_18585757_18584198_18584382_18586082_18586208
0.00187
0.281
DataSet_01_98
View details
ACAA1
38167652_38167822_38167316_38167372_38168000_38168115
0.00972
0.077
DataSet_01_98
View details
ADD1
2928365_2928402_2927740_2927839_2929897_2931054
0.00274
0.055
DataSet_01_98
View details
ADD1
2928368_2928402_2927740_2927839_2929897_2931789
0.00418
0.058
DataSet_01_98
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ADD1
2911065_2911158_2910241_2910331_2916610_2916767
0.00551
0.043
DataSet_01_98
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AHSA2
61413114_61413216_61412636_61412753_61413580_61413632
0.00001
0.258
DataSet_01_98
View details
Showing 1 to 10 of 228 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AC002116.8
36503922_36503991_36504245_36504324_36502305_36502366
0.00487
-0.167
DataSet_01_98
View details
ACBD4
43214385_43214506_43214734_43214821_43214058_43214143
0.00023
-0.602
DataSet_01_98
View details
AFP
74306318_74306530_74309067_74309161_74303890_74304023
0.00010
-0.091
DataSet_01_98
View details
AHSG
186336079_186336280_186337645_186337702_186334975_186335139
0.00000
-0.348
DataSet_01_98
View details
AHSG
186336079_186336280_186336285_186336426_186334975_186335139
0.00001
-0.011
DataSet_01_98
View details
AHSG
186336079_186336280_186336300_186336426_186334975_186335139
0.00001
-0.142
DataSet_01_98
View details
AHSG
186336079_186336280_186336285_186336426_186334975_186335139
0.00001
-0.144
DataSet_01_98
View details
AHSG
186336079_186336280_186336300_186336426_186334975_186335139
0.00003
-0.011
DataSet_01_98
View details
AHSG
186336079_186336280_186337645_186337863_186334975_186335139
0.00006
-0.261
DataSet_01_98
View details
ALB
74283804_74283852_74283982_74284028_74283247_74283386
0.00020
0.205
DataSet_01_98
View details
Showing 1 to 10 of 73 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AMICA1
118082944_118083184_118083121_118083184_118081201_118081427
0.00312
0.221
DataSet_01_98
View details
ATG16L1
234181611_234182423_234181611_234181698_234183321_234183424
0.00508
0.352
DataSet_01_98
View details
ATXN2L
28847253_28847806_28847253_28847443_28848048_28848558
0.00120
-0.179
DataSet_01_98
View details
CFB
31915732_31915971_31915732_31915858_31916150_31916289
0.00692
0.027
DataSet_01_98
View details
CYC1
145150388_145150598_145150388_145150576_145150735_145150932
0.00562
-0.499
DataSet_01_98
View details
EIF4G2
10823207_10823756_10823595_10823756_10822496_10822634
0.00269
0.072
DataSet_01_98
View details
ENO2
7025817_7025998_7025817_7025893_7026201_7026423
0.00000
-0.118
DataSet_01_98
View details
ENO2
7025817_7026014_7025817_7025893_7026201_7026423
0.00111
-0.069
DataSet_01_98
View details
HNRNPH1
179043869_179044111_179044021_179044111_179043098_179043219
0.00003
0.065
DataSet_01_98
View details
IL32
3117377_3117614_3117377_3117416_3117984_3118011
0.00040
0.067
DataSet_01_98
View details
Showing 1 to 10 of 23 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACIN1
23532137_23532307_23532137_23532283_23532644_23532786
0.00060
0.044
DataSet_01_98
View details
ACIN1
23532137_23532307_23532137_23532246_23532644_23532786
0.00185
-0.09
DataSet_01_98
View details
ACTG1
79478213_79478829_79478213_79478652_79478928_79479168
0.00834
0.007
DataSet_01_98
View details
AP1G2
24031170_24031372_24031170_24031275_24031496_24031624
0.00055
-0.071
DataSet_01_98
View details
APOB
21265232_21265410_21265232_21265348_21266384_21266423
0.00697
-0.009
DataSet_01_98
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ARL16
79649063_79649705_79649063_79649179_79650042_79650148
0.00507
0.213
DataSet_01_98
View details
ASNS
97483891_97484066_97483891_97483992_97484664_97484771
0.00611
-0.042
DataSet_01_98
View details
ATP6V1G2-DDX39B
31508258_31508354_31508258_31508311_31509726_31509925
0.00000
-0.266
DataSet_01_98
View details
ATP6V1G2-DDX39B
31508258_31508343_31508258_31508311_31509726_31509925
0.00768
-0.175
DataSet_01_98
View details
CDC27
45229171_45229302_45229171_45229284_45232037_45232152
0.00474
-0.059
DataSet_01_98
View details
Showing 1 to 10 of 44 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACADVL
7123782_7123995_7123782_7123848_7123922_7123995
0.00658
-0.037
DataSet_01_98
View details
AHSA2
61412636_61413632_61412636_61412753_61413580_61413632
0.00009
0.158
DataSet_01_98
View details
ANKZF1
220097800_220098155_220097800_220097913_220098007_220098155
0.00318
-0.065
DataSet_01_98
View details
ANKZF1
220100731_220101373_220100731_220100817_220101043_220101373
0.00700
-0.029
DataSet_01_98
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APOA2
161193170_161193418_161193170_161193215_161193384_161193418
0.00169
0.392
DataSet_01_98
View details
ATG16L2
72533522_72535887_72533522_72533588_72533892_72535887
0.00112
-0.471
DataSet_01_98
View details
ATXN2L
28847253_28848558_28847253_28847443_28848048_28848558
0.00039
-0.129
DataSet_01_98
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CD46
207940357_207943707_207940357_207940540_207943665_207943707
0.00202
-0.099
DataSet_01_98
View details
CHD4
6692192_6692544_6692192_6692279_6692363_6692544
0.00885
0.035
DataSet_01_98
View details
COX4I1
85838542_85839470_85838542_85838710_85839338_85839470
0.00569
0.011
DataSet_01_98
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Showing 1 to 10 of 42 entries
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
28836974
A
G
9.88453E-07
SNHG3,RCC1
+
TRUE
AluSc
SINE,Alu
chr1
222713503
C
G
0.00860
HHIPL2
-
FALSE
chr1
19542250
T
C
9.94571E-09
LOC101927895,EMC1
+,-
FALSE
AluSz
SINE,Alu
chr1
31732603
A
C
0.00164
SNRNP40
-
FALSE
chr1
16933642
G
A
0.00679
NBPF1
-
FALSE
GA-rich
SINE,Alu
chr1
9416151
G
A
0.00292
SPSB1
+
FALSE
chr1
120163518
C
T
0.00646
ZNF697
-
FALSE
chr1
21100856
A
C
0.00010
HP1BP3
-
FALSE
(AC)n
SINE,Alu
chr1
38478446
C
G
4.10892E-09
UTP11
+
FALSE
chr1
10521170
T
C
0.00498
DFFA
-
TRUE
AluY
SINE,Alu
Showing 1 to 10 of 499 entries
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression