Dataset Overview
RBPMSI1
Knock-MethodsiRNA
RBP FamilyRRM_1
Biosample NameU251
Tissue TypeGlioblastoma
Biosample TypeCell line
# of Control3
# of Treat3
SpeciesHuman
Data SourceGEO
Profile IDGSE68800
PlatformGPL11154
Pubmed ID26100017

MSI1 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of MSI1
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of MSI1


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr1201846630CA7.51318E-05IPO9+FALSE(CA)nSINE,Alu
chr1453242417TC0.00423GNPNAT1-TRUEAluJoSINE,Alu
chr129631909AG0.00029PTPRU+FALSE
chr159122059GA0.00476MYSM1-FALSE
chr1155161702GC0.00020MUC1-FALSE
chr116890130AC0.00412NBPF1-FALSE
chr1175914284AG0.00036RFWD2-FALSE
chr119071752TC0.00503PAX7+FALSE
chr116133987TC0.00830UQCRHL-FALSE
chr72473753CT0.00806CHST12+FALSE(CCGC)nSINE,Alu
chr337317605AG9.02711E-05GOLGA4+FALSE
chr119542458TC6.76498E-05LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr16582498TC0.00403NOL9-TRUEAluSx1SINE,Alu
chr132631809CT2.91083E-08KPNA6+FALSE
chr417802772GT0.00328DCAF16-FALSEAluSzSINE,Alu
chr1610624905TC1.13117E-09EMP2-FALSEAluSx3SINE,Alu
chr344790624TC0.00150KIAA1143-TRUEAluYSINE,Alu
chr315112631AG0.00019RBSN-FALSE
chr3196557274CT0.00285PAK2+FALSE
chr42940265TC4.71601E-06NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr199761591TC0.00516ZNF562-TRUEAluSpSINE,Alu
chr2206981832TC0.00251.FALSEAluJbSINE,Alu
chr42940477TC1.61307E-05NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr5180663939CA0.00190RACK1-FALSE
chr128824065CT0.00345PHACTR4+FALSE
chr168940887TG0.00293DEPDC1-FALSEMIRSINE,Alu
chr1204520250AG0.00706MDM4+TRUEAluJbSINE,Alu
chr1109747415AG0.00549KIAA1324+TRUEAluJr4SINE,Alu
chr3182614493TC0.00036ATP11B+FALSE
chr124999468GT0.00075SRRM1+FALSE(T)nSINE,Alu
chr344791062TC0.00035KIAA1143-FALSE
chr3183900836GA2.54977E-05AP2M1+FALSE
chr1172411496AG0.00361C1orf105,PIGC+,-FALSE
chr110521238TC0.00597DFFA-TRUEAluYSINE,Alu
chr1675479250TC0.00568TMEM170A-TRUEAluJbSINE,Alu
chr410076959CG6.37978E-10WDR1-FALSE
chr1145273345TC0.00190NBPF20,NOTCH2NL+FALSE
chr356703746AC0.00027FAM208A-FALSE
chr5137891109CG0.00031HSPA9-FALSE
chr12123346990GT0.00055HIP1R+FALSE
chr1567489TC0.00119.FALSE
chr146075715AG0.00401NASP+TRUEAluSx4SINE,Alu
chr766421684TG0.00042TMEM248+FALSEAluJrSINE,Alu
chr652860743TG1.01575E-05.FALSE7SKSINE,Alu
chr1717971644GT0.00154GID4+FALSE
chr2206983267TC0.00133.FALSEAluJbSINE,Alu
chr3141668758TC2.84489E-05TFDP2-TRUEAluSzSINE,Alu
chr153679610GA0.00119CPT2+FALSEAluSzSINE,Alu
chr775958129TA0.00162YWHAG-FALSE
chr517276080AC0.00298BASP1+FALSE(TC)nSINE,Alu
chr119543456TC0.00451LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr1214529320TG0.00365PTPN14-FALSEAluJbSINE,Alu
chr315115270GT0.00177RBSN-FALSE
chr2227600369AG0.00577IRS1-FALSE
chr119665557AC0.00365CAPZB-FALSE
chr1144955288AG0.00574NBPF20,PDE4DIP+,-FALSE
chr110518821TC0.00913.FALSEAluSx1SINE,Alu
chr237330611TC0.00835.FALSEAluSq2SINE,Alu
chr1150281090AG3.10555E-05MRPS21+TRUEAluSzSINE,Alu
chr579923292CG0.00305DHFR-FALSEAluJrSINE,Alu
chr41305799CT0.00730MAEA+FALSE
chr4169847647AT0.00328PALLD+FALSE
chr2233446265TC0.00177EIF4E2+FALSE
chr153291435AG0.00044ZYG11B+TRUEAluJrSINE,Alu
chr12990912AC0.00244WNK1+FALSE
chr2101893247CA0.00237RNF149-FALSE(A)nSINE,Alu
chr119653870TC0.00477PQLC2+FALSE
chr165690461GA0.00115AK4+FALSE
chr2191366707AG0.00900MFSD6+FALSE
chr110519064TC0.00012.FALSEAluSx3SINE,Alu
chr167895926AG0.00705SERBP1-FALSE
chr16283430TC0.00751ICMT-TRUEAluSx3SINE,Alu
chr642045545AG0.00440TAF8+TRUEAluSzSINE,Alu
chr165696034GC0.00803AK4+FALSE
chr1949608GA0.00235ISG15+FALSE
chr812286573GA0.00052FAM86B2-FALSE
chr8144827207AT0.00038FAM83H-AS1+FALSEERVL-B4-intSINE,Alu
chr116918717CT0.00550NBPF1-FALSE
chr4184238324GA0.00870WWC2+FALSE
chr1495555551CT0.00404DICER1-FALSE
chr1774555106TC0.00164SNHG16+FALSE
chr1610624967TC0.00013EMP2-TRUEAluSx3SINE,Alu
chr340577810AG0.00896ZNF621+TRUEAluSzSINE,Alu
chr1292537702TA0.00368BTG1-FALSE
chr19163383TC0.00383.FALSEAluSpSINE,Alu
chr110520058TC0.00907.FALSEAluSxSINE,Alu
chr237075013TA0.00119STRN-FALSE
chr1144932200GT0.00492NBPF20,PDE4DIP+,-FALSE
chr595222277CT0.00599ELL2-FALSE
chr11593060TC5.25946E-05CDK11B,SLC35E2B-FALSE
chr2218572730AG6.64824E-05PEX26+TRUEAluYf1SINE,Alu
chr137949224CT7.78396E-10ZC3H12A+FALSE
chr1942375627AG0.00058.FALSEAluSxSINE,Alu
chr1145284432GA0.00795NBPF20,NOTCH2NL+FALSE
chr140537941AC0.00489CAP1+FALSE(A)nSINE,Alu
chr125890189AG0.00961LDLRAP1+FALSE
chr1741144581AC0.00806RUNDC1+FALSEAluSxSINE,Alu
chr1472041443CT0.00842SIPA1L1+FALSE
chr126226610CT0.00955STMN1-FALSE
chr153679610GA0.00073CPT2+FALSEAluSzSINE,Alu
chr179109353GT0.00214IFI44L+FALSELTR26SINE,Alu
chr1165544342TC3.74920E-05AP5B1-TRUEAluJbSINE,Alu
chr7137561083TC0.00194CREB3L2-FALSE(GT)nSINE,Alu
chr19162929CG0.00584.FALSE
chr237331531TC0.00063.FALSEAluJbSINE,Alu
chr145504720GC0.00759ZSWIM5-FALSE
chr192862888AG0.00029.FALSEAluJrSINE,Alu
chr9131872853CG0.00108CRAT-FALSE
chr125894469AT0.00326LDLRAP1+FALSEMIRbSINE,Alu
chr333909024AT0.00134PDCD6IP+FALSE
chr314986471TC3.70393E-05FGD5-AS1-TRUEAluSq2SINE,Alu
chr6160101733TC0.00784SOD2-TRUEAluSzSINE,Alu
chr29770610AG0.00466YWHAQ-FALSE
chr1110604747GA0.00739ALX3-FALSE
chr12133298125AG0.00025PGAM5+TRUEAluJoSINE,Alu
chr47764501TA5.61153E-09AFAP1,AFAP1-AS1+,-FALSE
chr116974666CT0.00131MST1P2+FALSE
chr153378536TC0.00075ECHDC2-TRUEAluSpSINE,Alu
chr42940165TC0.00201NOP14-AS1,NOP14+,-FALSEAluSpSINE,Alu
chr136067784TC0.00083PSMB2-TRUEAluSzSINE,Alu
chr120811795GC0.00047CAMK2N1-FALSE
chr1272096335AG1.07858E-05TMEM19+FALSEAluSz6SINE,Alu
chr417802819TC0.00112DCAF16-TRUEAluSzSINE,Alu
chr3156259288TC0.00072SSR3-TRUEAluSq2SINE,Alu
chr4186081538TA0.00077CFAP97-FALSE
chr1112258252AG0.00224RAP1A+FALSE
chr1206578650GC0.00159SRGAP2+FALSE
chr136068276TC5.36857E-05PSMB2-TRUEAluScSINE,Alu
chr1161930908GA0.00083ATF6+FALSE
chr3122283292CG0.00047DTX3L,PARP9+,-FALSE
chr2192699639AG0.00017SDPR-FALSE
chr1161141432CG0.00508B4GALT3-FALSE
chr237331555TC0.00171.FALSEAluJbSINE,Alu
chr261277443AG0.00362PEX13+TRUEAluSxSINE,Alu
chr1100657328AG0.00682DBT-FALSE(AC)nSINE,Alu
chr2118940466AT0.00169CXADR+FALSEAluYSINE,Alu
chr340578933AG0.00947ZNF621+TRUEAluJrSINE,Alu
chr11662694TC0.00398SLC35E2-TRUEAluYSINE,Alu
chr642854664AG5.02680E-07RPL7L1+TRUEAluScSINE,Alu
chr532586387TC0.00569SUB1+FALSE
chr1110136846TA0.00639GNAI3+FALSE
chr110518037TC0.00017.FALSEAluJrSINE,Alu
chr5115165591TC0.00407ATG12-TRUEAluSq2SINE,Alu
chr145279898CT0.00271.FALSE(TCTT)nSINE,Alu
chr1154554940GC0.00032ADAR-FALSE
chr3158547143GA0.00178MFSD1+FALSE
chr116907328GT0.00973NBPF1-FALSE
chr5204215AG0.00872.FALSEMER68SINE,Alu
chr794297301GT0.00145PEG10+FALSE
chr2132279046GT0.00967LOC150776+FALSE
chr232535568AG0.00192.FALSEMER8SINE,Alu
chr537291636TC0.00518.FALSEAluSx3SINE,Alu
chr373024350CA0.00109GXYLT2+FALSE
chr8146200271TC0.00182ZNF252P-TRUEAluScSINE,Alu
chr128662254AG0.00290MED18+TRUEAluSq2SINE,Alu
chr110240685CT0.00422UBE4B+FALSE
chr146078630AG4.65755E-11NASP+FALSE
chr5131715011AG0.00761SLC22A5+FALSE
chr1241794056CA0.00753OPN3,CHML-FALSE
chr2217498311TC0.00977IGFBP2+FALSE(CCG)nSINE,Alu
chr1231377081CT0.00895GNPAT+FALSE
chr1173864944GT2.40127E-05.FALSE
chr129848629AG0.00027CLEC2D+FALSE
chr128261658TG0.00280SMPDL3B+FALSE
chr595236459CT0.00330ELL2-FALSE
chr2101635538CT0.00069TBC1D8,RPL31+,-FALSECharlie17SINE,Alu
chr1245008386GC0.00041.FALSEMER2SINE,Alu
chr140435513CA0.00656MFSD2A+FALSE
chr138423235CA0.00040SF3A3-FALSEAluJoSINE,Alu
chr112677549TA1.84464E-05DHRS3-FALSE(A)nSINE,Alu
chr165297860AT0.00847RAVER2+FALSE
chr129644328CT0.00076PTPRU+FALSE
chr11655474GA0.00694CDK11B,CDK11A-FALSE
chr579276281AG0.00026MTX3-FALSE
chr11593857TC0.00424CDK11B,SLC35E2B-FALSE
chr3138121198CT0.00076MRAS+FALSE
chr373112378AG0.00261PPP4R2,EBLN2+FALSE
chr9133579674AG0.00018EXOSC2+TRUEAluSx3SINE,Alu
chr1742880190TC0.00284GJC1-TRUEAluJbSINE,Alu
chr111847346GC0.00547C1orf167,MTHFR+,-FALSE
chr540832552GT1.14652E-07RPL37-FALSE
chr145116985CT0.00318RNF220+FALSE
chr495588274GA0.00095PDLIM5+FALSE
chr3120113286CT1.47726E-06FSTL1-FALSE
chr1200375418CT0.00425ZNF281-FALSE
chr170718278CG0.00663.FALSE
chr811700444CG0.00042CTSB-FALSEAluSq2SINE,Alu
chr842043493GA0.00045PLAT-FALSEMLT2C1SINE,Alu
chr413604418GC2.95746E-07BOD1L1-FALSE
chr1373651653GT0.00532KLF5+FALSE
chr128150601AT0.00558STX12+FALSE
chr228002603CA0.00010MRPL33+FALSE
chr393846831GA0.00547.FALSEAluSq2SINE,Alu
chr2202242616GA0.00880TRAK2-FALSE
chr1110913120CT0.00627SLC16A4-FALSE
chr3194789330GT0.00699XXYLT1-FALSEAluJrSINE,Alu
chr1748828384GT0.00283LUC7L3+FALSE
chr110520684TC0.00842DFFA-TRUEAluSc8SINE,Alu
chr116411935TC0.00905SMPD1+FALSE(CTGGCG)nSINE,Alu
chr5109202858GA0.00054MAN2A1+FALSE(A)nSINE,Alu
chr154493197TC0.00064TMEM59-TRUEAluSz6SINE,Alu
chr1171751051AG0.00522METTL13+FALSE
chr151873951GA0.00588EPS15-FALSE
chr187573349CG0.00914HS2ST1+FALSE
chr11593828GC0.00348CDK11B,SLC35E2B-FALSE
chr315114306TC0.00036RBSN-TRUEAluYSINE,Alu
chr5139931627CT0.00073SRA1-FALSE
chr9130268408TC0.00416FAM129B-FALSE(CTCA)nSINE,Alu
chr996438974CG0.00303PHF2+FALSE(CTCCAC)nSINE,Alu
chr116889820CT0.00012NBPF1-FALSE
chr3160213318TG0.00215KPNA4-FALSE
chr349067308GA0.00278QRICH1-FALSE
chr1183213770GC0.00734LAMC2+FALSE
chr344791536TC4.11776E-05KIAA1143-TRUEAluJrSINE,Alu
chr11118880839AG0.00922CCDC84+TRUEAluJbSINE,Alu
chr1911560483AG0.00775PRKCSH+TRUEAluSxSINE,Alu
chr191981317TA0.00539CSNK1G2+FALSE
chr344790759TC0.00744KIAA1143-TRUEAluYSINE,Alu
chr116133987TC0.00707UQCRHL-FALSE
chr3196080624TC0.00795UBXN7-TRUEAluSxSINE,Alu
chr133149486AG0.00528SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr398531342AG0.00607DCBLD2-FALSE
chr199673275TC0.00081.FALSETigger1SINE,Alu
chr1120164994CT0.00829ZNF697-FALSE
chr2187544222AG0.00411ITGAV+FALSE
chr119542250TC0.00859LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr132697071CA0.00134EIF3I+FALSEAluSpSINE,Alu
chr1146400122CG0.00039NBPF20,NBPF10,NBPF25P,NBPF12+FALSE
chr4177252238AG9.63526E-05SPCS3+TRUE

Differential Expression Gene Analysis