Dataset Overview
RBP
SRSF1
Knock-Method
siRNA
RBP Family
RRM_1
Biosample Name
Foreskin keratinocytes
Tissue Type
Foreskin
Biosample Type
Cell line
# of Control
3
# of Treat
3
Species
Human
Data Source
GEO
Profile ID
GSE114529
Platform
GPL18573
Pubmed ID
30380419
SRSF1 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of SRSF1
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A1BG
2.32
0.58
-1.36975
0.01197
0.05148
A1BG-AS1
1.68
1.16
-0.89561
0.00489
0.02619
A2ML1
34.19
10.96
-1.73086
3.07957E-28
5.01593E-25
A4GALT
15.74
10.8
-0.49391
0.01837
0.07119
AAAS
21.54
14.48
-0.58069
0.00128
0.00927
AAK1
14.11
18.54
0.33670
0.02972
0.10059
AASDHPPT
22.06
14.25
-0.54315
0.00147
0.01025
ABAT
8.49
12.62
0.57112
0.00037
0.00349
ABCA10
0.22
0.66
1.40374
0.00043
0.00386
ABCA2
2.78
4.21
0.49378
0.00867
0.04036
Showing 1 to 10 of 4,920 entries
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Function Analysis of Target Genes of SRSF1
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABI1
27044583_27044670_27040526_27040712_27047990_27048164
0.00018
-0.5
DataSet_02_107
View details
ABI2
204260378_204260503_204259422_204259569_204267298_204267457
0.00010
-0.467
DataSet_02_107
View details
AC010522.1
58331861_58331917_58331086_58331313_58367474_58367601
0.00283
0.556
DataSet_02_107
View details
AC068580.4
1774762_1774900_1768976_1769349_1775032_1775131
0.00070
0.54
DataSet_02_107
View details
AC069544.2
14884132_14884845_14882073_14882156_14885369_14886726
0.00000
0.684
DataSet_02_107
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ACP1
275139_275201_272036_272150_276979_277085
0.00319
-0.533
DataSet_02_107
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ACSL4
108939372_108939425_108926364_108926895_108976367_108976442
0.00093
-0.349
DataSet_02_107
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ADAM15
155034379_155034451_155033890_155033965_155034720_155034845
0.00278
-0.333
DataSet_02_107
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ADAMTSL5
1511623_1511726_1510843_1510916_1512961_1513018
0.00032
0.778
DataSet_02_107
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ADRM1
60879516_60879633_60878623_60878837_60881252_60881376
0.00119
-0.12
DataSet_02_107
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Showing 1 to 10 of 539 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABI1
27044583_27044670_27047990_27048167_27040526_27040712
0.00240
0.375
DataSet_02_107
View details
ACTN4
39218585_39218666_39218955_39219021_39217596_39217743
0.00075
-0.311
DataSet_02_107
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ADAM15
155033238_155033308_155033893_155033965_155032680_155032819
0.00739
0.078
DataSet_02_107
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ADAM15
155033890_155033965_155034379_155034451_155033238_155033308
0.00022
0.357
DataSet_02_107
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ADAM15
155033893_155033965_155034379_155034451_155033238_155033308
0.00015
0.445
DataSet_02_107
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ANXA2
60682411_60682516_60688349_60688626_60678226_60678285
0.00000
-0.75
DataSet_02_107
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ANXA2
60682411_60682516_60688571_60688626_60678226_60678285
0.00000
-0.611
DataSet_02_107
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ANXA2
60682411_60682516_60689456_60689537_60678226_60678285
0.00047
-0.402
DataSet_02_107
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ANXA2
60688571_60688626_60689456_60689537_60678226_60678285
0.00002
0.441
DataSet_02_107
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ARPP19
52856386_52856443_52861044_52861097_52849296_52849419
0.00457
0.051
DataSet_02_107
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Showing 1 to 10 of 39 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AFAP1L2
116056978_116057172_116056990_116057172_116056736_116056859
0.00004
-0.308
DataSet_02_107
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AL365277.1
39994687_39994836_39994726_39994836_39987951_39988177
0.00000
-1.0
DataSet_02_107
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ANO9
429473_429652_429569_429652_428721_428826
0.00463
0.153
DataSet_02_107
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ANPEP
90348176_90348448_90348308_90348448_90347721_90347848
0.00833
0.084
DataSet_02_107
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APEX1
20923384_20923548_20923384_20923487_20923736_20923862
0.00948
0.408
DataSet_02_107
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ARPC1B
98974960_98975078_98974960_98975062_98983324_98983401
0.00001
0.493
DataSet_02_107
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ATG16L1
234181611_234182423_234181611_234181698_234183321_234183424
0.00163
-0.566
DataSet_02_107
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C20orf27
3740653_3740833_3740728_3740833_3739182_3739325
0.00828
0.071
DataSet_02_107
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CNBP
128890476_128890614_128890494_128890614_128890288_128890381
0.00041
0.415
DataSet_02_107
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CNBP
128890494_128890614_128890497_128890614_128890288_128890381
0.00256
-0.434
DataSet_02_107
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Showing 1 to 10 of 76 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACTG1
79478928_79479168_79478928_79479141_79479257_79479386
0.00484
-0.318
DataSet_02_107
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AK1
130635304_130635459_130635304_130635340_130636889_130636928
0.00392
-0.228
DataSet_02_107
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ARMCX2
100914061_100914134_100914061_100914122_100914404_100914487
0.00304
-0.464
DataSet_02_107
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ATP10D
47538702_47538955_47538747_47538955_47538453_47538581
0.00065
-0.374
DataSet_02_107
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AUP1
74754067_74754248_74754067_74754186_74754374_74754490
0.00003
0.5
DataSet_02_107
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BRD8
137502206_137502416_137502206_137502299_137503622_137503767
0.00069
0.556
DataSet_02_107
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C12orf75
105761249_105761287_105761254_105761287_105760394_105760474
0.00813
-0.25
DataSet_02_107
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CARS
3023199_3023830_3023199_3023283_3026595_3026663
0.00095
-0.348
DataSet_02_107
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CDK13
40132383_40132836_40132563_40132836_40127724_40127930
0.00009
0.163
DataSet_02_107
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CHMP4A
24680616_24680798_24680616_24680718_24680885_24681035
0.00000
-0.889
DataSet_02_107
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ALKBH2
109530311_109531277_109530311_109530592_109531051_109531277
0.00013
0.163
DataSet_02_107
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ALS2CL
46712977_46713523_46712977_46713258_46713373_46713523
0.00002
0.308
DataSet_02_107
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APEX1
20923384_20923862_20923384_20923548_20923736_20923862
0.00008
-0.565
DataSet_02_107
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ARHGDIA
79827205_79827501_79827205_79827282_79827417_79827501
0.00024
0.472
DataSet_02_107
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ARTN
44401740_44402018_44401740_44401903_44401973_44402018
0.00984
0.156
DataSet_02_107
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AUP1
74754067_74754490_74754067_74754186_74754374_74754490
0.00011
0.467
DataSet_02_107
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CAPN1
64977319_64977567_64977319_64977388_64977488_64977567
0.00441
0.342
DataSet_02_107
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CARM1
11031509_11031803_11031509_11031622_11031725_11031803
0.00234
0.183
DataSet_02_107
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CARS
3023199_3023830_3023199_3023404_3023770_3023830
0.00347
-0.153
DataSet_02_107
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CD164L2
27705665_27706685_27705665_27705999_27706540_27706685
0.00983
-0.352
DataSet_02_107
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
28864731
A
G
0.00477
RCC1
+
FALSE
chr1
144481235
A
G
1.18230E-05
NBPF20
+
FALSE
chr1
145512073
A
G
0.00505
NBPF20,NBPF10,RBM8A,GNRHR2
+,-
FALSE
AluY
SINE,Alu
chr1
212114666
C
G
0.00858
INTS7
-
FALSE
chr1
53289892
A
G
0.00079
ZYG11B
+
TRUE
FRAM
SINE,Alu
chr1
146649884
T
A
0.00338
PDIA3P1
+
FALSE
chr1
6932082
T
A
0.00330
CAMTA1
+
FALSE
chr1
1683565
G
A
0.00269
NADK
-
FALSE
chr1
10517513
T
C
0.00088
.
FALSE
AluSx1
SINE,Alu
chr1
214524496
T
C
0.00114
PTPN14
-
TRUE
AluSg
SINE,Alu
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression