Dataset Overview
RBPSRSF1
Knock-MethodsiRNA
RBP FamilyRRM_1
Biosample NameForeskin keratinocytes
Tissue TypeForeskin
Biosample TypeCell line
# of Control3
# of Treat3
SpeciesHuman
Data SourceGEO
Profile IDGSE114529
PlatformGPL18573
Pubmed ID30380419

SRSF1 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of SRSF1
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of SRSF1


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr128864731AG0.00477RCC1+FALSE
chr237331546TC0.00694.FALSEAluJbSINE,Alu
chr1681064533AG0.00686CENPN+TRUEAluSgSINE,Alu
chr3195701388GA0.00274SDHAP1-FALSE
chr1144481235AG1.18230E-05NBPF20+FALSE
chr1145512073AG0.00505NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr47764131AT5.82585E-11AFAP1,AFAP1-AS1+,-FALSE
chr1212114666CG0.00858INTS7-FALSE
chr5130537747AG1.40133E-05LYRM7+TRUEAluJbSINE,Alu
chr5149763305AG0.00640TCOF1+FALSE
chr425253995CT9.95051E-10PI4K2B+FALSE
chr153289892AG0.00079ZYG11B+TRUEFRAMSINE,Alu
chr2208619320AG0.00339CCNYL1+FALSEEutTc1-N1SINE,Alu
chr1146649884TA0.00338PDIA3P1+FALSE
chr16932082TA0.00330CAMTA1+FALSE
chr11683565GA0.00269NADK-FALSE
chr273957124AG2.00679E-05TPRKB-FALSE
chr9132268259AG0.00032LINC00963+TRUEAluJbSINE,Alu
chr110517513TC0.00088.FALSEAluSx1SINE,Alu
chr1214524496TC0.00114PTPN14-TRUEAluSgSINE,Alu
chr11717439TA0.00663GNB1-FALSE
chr1155282600AG0.00019FDPS+TRUEAluSpSINE,Alu
chrX9863112AG0.00498SHROOM2+FALSE
chr237327677TC0.00019.FALSE
chr1476680377TA0.00143.FALSEL1M5SINE,Alu
chr23592602TC0.00232RNASEH1-TRUEAluSz6SINE,Alu
chr237330614TC0.00410.FALSEAluSq2SINE,Alu
chr11169973GA0.00783B3GALT6+FALSE
chr12125511942AG0.00015THRIL-FALSEAluSx1SINE,Alu
chr1182569318GT0.00829RGS16-FALSE
chr438946481AG0.00168FAM114A1+FALSEMER1BSINE,Alu
chr1179829096TC4.38746E-06TOR1AIP2-TRUEAluJrSINE,Alu
chr237329300TC0.00092.FALSEAluJr4SINE,Alu
chr1946053316TC4.53847E-05OPA3-TRUEAluSx1SINE,Alu
chr236704033TA0.00012CRIM1+FALSE
chr186815303TC0.00571ODF2L-FALSE
chr1100489297GC0.00669SLC35A3+FALSEAluScSINE,Alu
chr1958356540AG0.00019ZNF587B+TRUEAluSxSINE,Alu
chr652442880GT5.05556E-08TRAM2-AS1+FALSE
chr11246978AT0.00760PUSL1,CPSF3L+,-FALSE
chr1109474776AG0.00149GPSM2,CLCC1+,-FALSEAluSzSINE,Alu
chr189299658GA0.00779PKN2+FALSE
chr581571878AT8.61300E-05RPS23-FALSE
chr1155161737GC0.00482MUC1-FALSE
chr1183876182CT0.00494RGL1+FALSE
chr799917927TC0.00320SPDYE3+FALSEAluJbSINE,Alu
chr136067760TC0.00768PSMB2-TRUEAluSzSINE,Alu
chr895805071AG1.12730E-06DPY19L4+TRUEAluYf1SINE,Alu
chr2220422583GA0.00089OBSL1-FALSE
chr1115248084CT0.00171NRAS-FALSE
chr2204298783AC0.00179RAPH1-FALSE(AT)nSINE,Alu
chr144088547CA0.00018PTPRF+FALSEA-richSINE,Alu
chr154493197TC0.00148TMEM59-TRUEAluSz6SINE,Alu
chr1610624905TC1.13117E-09EMP2-FALSEAluSx3SINE,Alu
chr1230416410GT0.00516GALNT2+FALSE
chr1789187CG5.07459E-05LINC01128+FALSE
chr744800040CA0.00565ZMIZ2+FALSE
chr116703162AT0.00726MRPL17-FALSE
chr1061548852GA0.00693CCDC6-FALSE
chr1204189357CT0.00835PLEKHA6-FALSE
chr1113672640AG0.00629.FALSEAluJbSINE,Alu
chr3119545349TC0.00805GSK3B-FALSE
chr19163405TC0.00014.FALSEAluSpSINE,Alu
chr285773689TC0.00104GGCX-TRUEAluSx1SINE,Alu
chr456298300GA7.51019E-06CLOCK-FALSE
chr41066073TA0.00387RNF212-FALSEL1MC1SINE,Alu
chr220424655GA0.00193SDC1-FALSE
chr133066859AG0.00403ZBTB8A+TRUEAluSq4SINE,Alu
chr127992824GA0.00025IFI6-FALSE
chr166058513AG0.00091LEPR+FALSE
chr125717365CG0.00229RHCE-FALSE
chr575469427GA0.00155SV2C+FALSE
chr177759578AG0.00031AK5+FALSE
chr269689699TC0.00800AAK1-TRUEAluSgSINE,Alu
chr1227953266GT0.00198KLHL42+FALSE
chrX16781687AG0.00298.FALSEAluSx1SINE,Alu
chr1745219755GT0.00592CDC27-FALSE
chr136068237TC0.00075PSMB2-TRUEAluScSINE,Alu
chr348787046TC0.00699PRKAR2A-TRUEAluSx3SINE,Alu
chr167874849TC0.00169SERBP1-TRUEAluSxSINE,Alu
chr1298943214AG4.64520E-05TMPO+TRUEAluSzSINE,Alu
chr1765334885TC2.77388E-05PSMD12-TRUEAluSqSINE,Alu
chr598128999GA0.00663RGMB+FALSE
chr126143726GT0.00128SEPN1+FALSEAluSxSINE,Alu
chr42516791TG4.75740E-05RNF4+FALSE
chr110368092AC0.00945KIF1B+FALSE
chr2062572487AC0.00390UCKL1-FALSE
chr11251841TC0.00915CPSF3L-TRUEAluSq2SINE,Alu
chr1749042289GT0.00737SPAG9-FALSEAluJbSINE,Alu
chr135648840GT0.00543SFPQ-FALSEAluSx3SINE,Alu
chr239664278CA0.00053MAP4K3-FALSE(CGC)nSINE,Alu
chr1648388258AG8.02686E-05MIR5095+TRUEAluSzSINE,Alu
chr1533064465CG0.00735FMN1-FALSE
chr190470915TA9.94810E-07ZNF326+FALSE
chr232535692AG0.00236.FALSEAluJbSINE,Alu
chr6109001952AG0.00978FOXO3+FALSE(A)nSINE,Alu
chr315113681TC0.00048RBSN-TRUEAluSz6SINE,Alu
chr439550967TC2.19217E-06UGDH-AS1,SMIM14+,-FALSEAluSzSINE,Alu
chr553841241TA0.00179SNX18+FALSE
chr1201845881AC0.00032IPO9+FALSE
chr187573963TC0.00787HS2ST1+FALSE
chr1156005447CA0.00337UBQLN4-FALSE
chr1144598641CT0.00250NBPF20+FALSE
chrX123046741AG0.00169XIAP+TRUEAluSzSINE,Alu
chr2100899665GA0.00758LONRF2-FALSE
chr16583383TC0.00305NOL9-TRUEAluSqSINE,Alu
chr136067752TC0.00402PSMB2-TRUEAluSzSINE,Alu
chr42940462TC6.45116E-07NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr119586455AG0.00772MRTO4+TRUEAluSzSINE,Alu
chr1230974329AG0.00355C1orf198-FALSE
chr2176791183TC0.00252LNPK-TRUEMSTDSINE,Alu
chr457326291AG0.00424PAICS+TRUEAluJrSINE,Alu
chrX2824933TC0.00066ARSD-TRUEAluSx1SINE,Alu
chr1214524178TC0.00265PTPN14-TRUEAluSxSINE,Alu
chr765618870AG0.00097CRCP+TRUEAluSx3SINE,Alu
chr3179117280TC0.00624GNB4-TRUEAluSzSINE,Alu
chr1298943192AG0.00011TMPO+FALSEAluSzSINE,Alu
chr2202028727AG0.00833CFLAR+TRUEAluSx1SINE,Alu
chr128826118AG0.00948PHACTR4+TRUEAluJbSINE,Alu
chr1569991TG0.00980.FALSE
chr968413593CA0.00342.FALSE
chr3195694448CT0.00025SDHAP1-FALSE
chr1145284883AG0.00329NBPF20,NOTCH2NL+FALSEL2aSINE,Alu
chr167874859TC0.00071SERBP1-TRUEAluSxSINE,Alu
chr1100489619AG0.00319SLC35A3+TRUE
chr1145689568AG8.25649E-05NBPF20,NBPF10+TRUEAluSgSINE,Alu
chr116932809CT0.00887NBPF1-FALSEL1MC2SINE,Alu
chr170696606CA0.00362SRSF11+FALSE
chr190049040AG0.00190LRRC8B+FALSE
chr8143763622CT0.00470PSCA+FALSE
chr119586519AG0.00310MRTO4+TRUEAluSzSINE,Alu
chr5118174745TC0.00084DTWD2-TRUEAluYSINE,Alu
chrX123046779AG0.00629XIAP+TRUEAluSzSINE,Alu
chr722983890TC0.00097FAM126A-FALSE
chr4190881971AC0.00183FRG1+FALSE
chr151822219GA0.00283EPS15-FALSE
chr152817432TC0.00518CC2D1B-TRUEAluSg4SINE,Alu
chr1204526554AG0.00194MDM4+TRUEAluSxSINE,Alu
chr1779838088TC6.81311E-05.FALSEAluSxSINE,Alu
chr165900357GT0.00851LEPR,LEPROT+FALSE
chr193465142TC0.00100NFIC+FALSE
chr143897496GA0.00481SZT2+FALSE
chr1231468953GA0.00085EXOC8-FALSE
chr42517223AG2.74855E-08RNF4+FALSE
chr1179852074TC0.00309TOR1AIP1+FALSE
chr1117531621AG0.00577PTGFRN+FALSE
chr345721874AG0.00314LIMD1,LIMD1-AS1+,-FALSEAluJbSINE,Alu
chr110093457CT0.00777UBE4B+FALSE
chr138155698GT0.00368C1orf109-FALSEAluSx1SINE,Alu
chr193826775TC0.00172DR1+FALSE
chr255255314AC0.00638RTN4-FALSE
chr116890320TC0.00045NBPF1-FALSE
chr16681836GA5.48259E-05PHF13+FALSE
chr314986098TC0.00996FGD5-AS1-TRUEFLAM_CSINE,Alu
chr110520378TC0.00047.FALSEAluSx1SINE,Alu
chr4110971055AT0.00048ELOVL6-FALSE
chr153289686AG0.00460ZYG11B+TRUEAluSzSINE,Alu
chr5128430757TC0.00338ISOC1+FALSE
chr116890639CT5.60894E-05NBPF1-FALSE
chr19328255AG0.00729H6PD+TRUEAluJrSINE,Alu
chr626368938CT0.00121BTN3A2+FALSE
chr3191097966TC1.34670E-13CCDC50+FALSE
chr1148003756TC0.00162NBPF8-TRUEL1MC4SINE,Alu
chr272403405AC0.00227EXOC6B-FALSEGA-richSINE,Alu
chr373115126AT0.00228PPP4R2+FALSE
chr220648946CT0.00531RHOB+FALSE
chr1204525548AG0.00027MDM4+TRUEAluSzSINE,Alu
chr1229762054TA0.00535URB2+FALSE
chr299812464AG1.88485E-05MRPL30+TRUEAluSxSINE,Alu
chr285548639AG0.00687TGOLN2-FALSE
chr11252513TC0.00013CPSF3L-TRUEAluSpSINE,Alu
chr2196602326TG0.00503SLC39A10+FALSE
chr1113001409CT2.24539E-06CTTNBP2NL+FALSEAluJrSINE,Alu
chr581571669CT0.00143RPS23-FALSE
chr1918476176AG0.00452PGPEP1+TRUEAluJbSINE,Alu
chr1946214293CT0.00137FBXO46-FALSE
chr5149829068CT0.00038RPS14-FALSE
chr47764501TA5.61153E-09AFAP1,AFAP1-AS1+,-FALSE
chr1165404866TG0.00664PCNX3+FALSE(T)nSINE,Alu
chr3155660873AG0.00018.FALSEAluSzSINE,Alu
chr3107773064TC0.00421CD47-TRUEFLAM_ASINE,Alu
chr133148706AG0.00087SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr1220231254TC0.00376RNU5F-1,BPNT1+,-FALSEAluYSINE,Alu
chr145244419TA0.00027.FALSE
chr126802401TG4.43852E-05HMGN2+FALSE
chr1168220341AG0.00179.FALSEAluSz6SINE,Alu
chr128608338AG0.00341SESN2+FALSE
chr12520435GC0.00041FAM213B+FALSE
chr124798520AC0.00110NIPAL3+FALSE
chr16582498TC0.00403NOL9-TRUEAluSx1SINE,Alu
chr1749042386TC4.28426E-05SPAG9-TRUEAluJbSINE,Alu
chr110042988AG3.32241E-06NMNAT1+TRUEAluScSINE,Alu
chr11684347CT0.00550NADK-FALSE
chr674133913TC0.00439.FALSEAluYSINE,Alu
chr1145511968AG0.00411NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr187573331TC0.00699HS2ST1+FALSE(AT)nSINE,Alu
chr177482018CA9.29146E-05SENP3-EIF4A1,EIF4A1+FALSE
chr4154257510AC0.00121TRIM2+FALSE(A)nSINE,Alu
chr116919961CT0.00133NBPF1-FALSE
chr193053116GC0.00276AES-FALSE
chr146164493TC0.00325IPP-TRUEAluJbSINE,Alu
chr344790772TC0.00024KIAA1143-TRUEAluYSINE,Alu
chr126608018GA2.25777E-05.FALSE
chr417802819TC0.00316DCAF16-TRUEAluSzSINE,Alu
chr1160967856TC0.00116F11R-TRUEAluSpSINE,Alu

Differential Expression Gene Analysis