Dataset Overview
RBPTRIM25
Knock-MethodsiRNA
RBP FamilyNon-canonical_RBP
Biosample NameMDA-231-D
Tissue TypeBreast
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceGEO
Profile IDGSE79586
PlatformGPL167891
Pubmed ID28813674

TRIM25 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of TRIM25
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of TRIM25


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr1203766872GA1.42518E-06ZC3H11A,ZBED6+FALSE
chr1144823139GA0.00941NBPF20,NBPF9+FALSE
chr333481400GC1.12603E-05UBP1-FALSE
chr132697110AT5.19592E-06EIF3I+FALSEAluSpSINE,Alu
chr133148367CG0.00020SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr1204520000AG0.00032MDM4+TRUECharlie2aSINE,Alu
chr165692499CT0.00930AK4+FALSE(T)nSINE,Alu
chr121793644GA0.00698NBPF3+FALSE
chr56372180CT0.00034MED10-FALSE
chr110519936TC0.00607.FALSEAluJrSINE,Alu
chr345126558CT0.00000CDCP1-FALSE
chr175288079AC0.00085RABEP1+FALSE
chr3184429155AT0.00056MAGEF1-FALSE
chr156961756AG0.00263PLPP3-FALSE
chr696054540GT0.00358MANEA+FALSE
chr9127711532TC0.00018SCAI-TRUEAluSpSINE,Alu
chr744917405CT0.00024PURB-FALSEAluSzSINE,Alu
chr5149829071TC0.00360RPS14-FALSE
chr1145273431AG0.00203NBPF20,NOTCH2NL+FALSE
chr19160982TC0.00304.FALSEAluJbSINE,Alu
chr1467852040AG4.57409E-05EIF2S1+TRUEAluJbSINE,Alu
chr613788297TC0.00077MCUR1-TRUEAluSxSINE,Alu
chr1145693958AG3.55543E-06NBPF20,NBPF10+TRUEAluSzSINE,Alu
chr1117529752CA0.00024PTGFRN+FALSE
chr1227071525CT0.00085PSEN2+FALSE
chr1668962CT0.00852.FALSE
chr4190864378TG0.00247FRG1+FALSEGA-richSINE,Alu
chr170904800GT0.00678CTH+FALSE
chr59546451GA0.00030SNHG18+FALSE
chr5139876355GA0.00815ANKHD1,ANKHD1-EIF4EBP3+FALSEGA-richSINE,Alu
chr110517952CA0.00341.FALSE
chr110518052TC0.00831.FALSEAluJrSINE,Alu
chr1109239334AT0.00035PRPF38B+FALSE
chr135658260CG0.00477SFPQ-FALSE
chr136067752TC5.48772E-07PSMB2-TRUEAluSzSINE,Alu
chr153684924AG0.00913C1orf123-FALSEL1MA5ASINE,Alu
chr457194712AC0.00399KIAA1211+FALSE
chr111347152AT0.00295UBIAD1+FALSE
chr1205739266CT0.00125RAB29-FALSE
chr133145958GT0.00080SYNC,RBBP4+,-FALSE(T)nSINE,Alu
chr1100489992AG0.00297SLC35A3+TRUEAluSgSINE,Alu
chr6150047423TC0.00688NUP43-TRUEAluScSINE,Alu
chr1146643580GA0.00113PRKAB2-FALSE
chr1226171340TC0.00462SDE2-TRUEBC200SINE,Alu
chr123636273AT0.00442HNRNPR-FALSE
chr179109353GT0.00214IFI44L+FALSELTR26SINE,Alu
chr1145283733AG0.00458NBPF20,NOTCH2NL+FALSE
chr537291446TC6.87884E-05.FALSEAluSx3SINE,Alu
chr4155457052TA0.00833PLRG1-FALSEL2d2SINE,Alu
chr139989926TC0.00354BMP8A,PPIEL+,-FALSE
chr439550715TC0.00995UGDH-AS1,SMIM14+,-FALSEAluSx1SINE,Alu
chr179109337GT0.00790IFI44L+FALSELTR26SINE,Alu
chr128662157AG0.00159MED18+TRUEAluSq2SINE,Alu
chr76694922GC0.00996ZNF316+FALSE
chr286947783CT0.00515RNF103-CHMP3,RMND5A+,-FALSE
chr140537924GA0.00245CAP1+FALSE(A)nSINE,Alu
chr1298943182AG1.41026E-08TMPO+TRUEAluSzSINE,Alu
chr1210006603CT0.00829DIEXF+FALSE
chr138327586CT0.00198INPP5B-FALSEAluSx3SINE,Alu
chr638670804GC0.00400GLO1-FALSE
chr1226259443CA0.00927H3F3AP4,H3F3A+FALSE
chr2140195059AG0.00817ETS2+FALSE
chr187328433TC3.09926E-06SEP15-FALSE
chr1776799795GA0.00363USP36-FALSE
chr298388811CG0.00123TMEM131-FALSE
chr110521238TC0.00096DFFA-TRUEAluYSINE,Alu
chr238971644TG0.00239SRSF7-FALSE
chr123636275GT0.00185HNRNPR-FALSE
chr135817022TA0.00072ZMYM4+FALSE
chr111782935AG0.00067.FALSEAluSxSINE,Alu
chr1758156064GA9.79781E-05HEATR6-FALSE
chr417804847TC0.00512DCAF16-TRUEAluSxSINE,Alu
chr825272447AT0.00770DOCK5+FALSE
chr2174773510TA0.00775SP3-FALSEA-richSINE,Alu
chr191486838GC0.00370ZNF644-FALSE
chr12133298349AG0.00000PGAM5+TRUEAluSpSINE,Alu
chr674134673TC0.00340.FALSEAluSzSINE,Alu
chr119578576GA0.00347MRTO4+FALSE
chr116576291AG0.00842FBXO42-FALSEA-richSINE,Alu
chr1211921422TG0.00686LPGAT1-FALSE
chr4177249593TG0.00038SPCS3+FALSE(T)nSINE,Alu
chr1145116027TC1.71852E-07NBPF20,SEC22B+FALSE
chr272403402CA0.00108EXOC6B-FALSEGA-richSINE,Alu
chr642856937AG0.00122RPL7L1+TRUEAluSpSINE,Alu
chr416258050CT0.00617TAPT1-AS1+FALSE
chr224224000AG0.00464.FALSEAluSpSINE,Alu
chr1158631171AC0.00815SPTA1-FALSE
chr2203744240TC0.00595.FALSEAluSxSINE,Alu
chr124935337AG0.00773NCMAP+TRUEAluJbSINE,Alu
chr1110951224AG0.00352LAMTOR5-AS1+TRUEAluJrSINE,Alu
chr1749041732TC0.00135SPAG9-TRUEAluSxSINE,Alu
chr19163096TC0.00185.FALSEFRAMSINE,Alu
chr1144922523CT0.00566NBPF20,PDE4DIP+,-FALSE
chr812879707TG0.00780KIAA1456+FALSE
chr1462262587TC0.00153SNAPC1+FALSEFLAM_CSINE,Alu
chr11595603CG0.00017CDK11B,SLC35E2B-FALSEAluJrSINE,Alu
chr138275802TC2.04657E-06MTF1-FALSE
chr11573181CA0.00038CDK11B-FALSE
chr136067817TC1.59583E-06PSMB2-TRUEAluSzSINE,Alu
chr1159946779GA0.00019LINC01133+FALSE(GAAA)nSINE,Alu
chr1145688664AT0.00087NBPF20,NBPF10,RNF115+FALSE
chr146076642AG0.00552NASP+TRUEAluSxSINE,Alu
chr2127826533AG0.00104BIN1-FALSE
chr176255228GA0.00073RABGGTB,SNORD45B+FALSE
chr1939433142TA0.00215FBXO17-FALSEAluJbSINE,Alu
chr1205577901GA0.00904ELK4-FALSE
chr1819445881TA0.00224MIB1+FALSE
chr165297860AT0.00847RAVER2+FALSE
chr192917287CA0.00243ZNF57+FALSE
chr119585554AG2.15626E-06MRTO4+TRUEAluSc8SINE,Alu
chr237328042TC6.80414E-06.FALSE
chrX77084042TC0.00703MAGT1-TRUEAluSzSINE,Alu
chr1153643449GC0.00704ILF2-FALSE
chr1229736656GC0.00793TAF5L-FALSE
chr10129910475TG0.00061MKI67-FALSE
chr2132481480TC0.00989C2orf27A+FALSE
chr11636355AG0.00857CDK11B,CDK11A-FALSE
chr1207247478CT0.00995PFKFB2+FALSEMER5BSINE,Alu
chr127052982TG0.00199C12orf57+FALSEU7SINE,Alu
chr132687475TC0.00785TMEM234,EIF3I+,-FALSE
chr2229890660AG0.00596PID1-FALSE
chr641888827CG0.00936MED20-FALSE
chr1145513112AG0.00080NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr153291435AG0.00049ZYG11B+TRUEAluJrSINE,Alu
chr116576295GA0.00139FBXO42-FALSEA-richSINE,Alu
chr123636028TA0.00029HNRNPR-FALSE
chr19811933CT0.00026PTBP1+FALSE
chr76063283CT0.00032AIMP2,EIF2AK1+,-FALSE
chr124128467CT0.00086HMGCL-FALSE
chr634213986TA0.00262HMGA1+FALSE
chr116889642TC0.00480NBPF1-TRUE
chr185787118GC0.00104DDAH1-FALSE
chr245640374CA0.00578SRBD1-FALSE
chr119545145AT0.00510LOC101927895,EMC1+,-FALSE
chr1109746825AG0.00094KIAA1324+TRUEAluJbSINE,Alu
chr2218696215AG0.00915TNS1-FALSE
chr2224622242TC0.00873AP1S3-TRUEAluSx1SINE,Alu
chr13371371CG0.00844ARHGEF16+FALSE
chr1115110683AC0.00168BCAS2-FALSE
chr453364GA0.00714ZNF718,ZNF595+FALSE
chr314986104TC0.00992FGD5-AS1-TRUEFLAM_CSINE,Alu
chr110521254TC0.00522DFFA-TRUEAluYSINE,Alu
chr17421931TC0.00260VPS53-TRUEAluSxSINE,Alu
chr162882267GC0.00252ZG16B+FALSE
chr133148623AG4.79591E-07SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr671298639AG0.00339.FALSEAluSpSINE,Alu
chr133149486AG5.00374E-05SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr560050122AT0.00272ELOVL7-FALSE
chr285548639AG0.00687TGOLN2-FALSE
chr1242719890AG0.00730ZCRB1-FALSE
chr2236957822GA0.00929AGAP1+FALSE
chr199672981TC0.00041.FALSEAluSx3SINE,Alu
chr1965489CA0.00494WASH5P-FALSEL2bSINE,Alu
chr1240255561GA0.00224FMN2+FALSE(GGC)nSINE,Alu
chr1144932220GT0.00449NBPF20,PDE4DIP+,-FALSE
chr269548320CT7.68354E-05GFPT1-FALSE
chr146075612AG0.00153NASP+TRUEAluSx4SINE,Alu
chr344790781TC0.00887KIAA1143-TRUEAluYSINE,Alu
chr2113334241AG0.00388POLR1B+TRUE
chr299812464AG1.88485E-05MRPL30+TRUEAluSxSINE,Alu
chr136024788CT5.60663E-14NCDN+FALSE
chr775677504CT0.00768MDH2+FALSE
chr2206987635TC0.00930.FALSEAluJbSINE,Alu
chr1145509570AG0.00043NBPF20,NBPF10,RBM8A+TRUEAluJrSINE,Alu
chr132697085TC0.00366EIF3I+FALSEAluSpSINE,Alu
chr726708303GT0.00095SKAP2-FALSEAluSx3SINE,Alu
chr211323106GT0.00860ROCK2-FALSE(TA)nSINE,Alu
chr128920944AG0.00446RAB42+TRUEAluSxSINE,Alu
chr1541593269AG0.00196.FALSEAluSz6SINE,Alu
chr1531619607GA0.00887KLF13+FALSE
chr2229904354GA0.00072THOC5-FALSE
chr3196659892TG0.00620SENP5+FALSEAluSzSINE,Alu
chr1953914819AG5.13713E-06ZNF765+TRUEAluSpSINE,Alu
chr1144931392GA0.00172NBPF20,PDE4DIP+,-FALSE
chr3194789663TC0.00754XXYLT1-FALSEMARNASINE,Alu
chr1490509582TC0.00017TDP1+FALSE
chr199673107TC1.71894E-07.FALSEAluSx3SINE,Alu
chr1212534448TC0.00926PPP2R5A+FALSE
chr6159396143TC0.00185.FALSEAluScSINE,Alu
chr237331560TC0.00040.FALSEAluJbSINE,Alu
chr1148561089TC0.00010NBPF15+FALSE
chr3124950421TA0.00713ZNF148-FALSE
chr417629921AG0.00454.FALSEMER90SINE,Alu
chr110519982TC0.00417.FALSEAluJrSINE,Alu
chr417629434AG0.00661.FALSEAluSx3SINE,Alu
chr76501830GA0.00217KDELR2-FALSE
chr140361783GC0.00023MYCL-FALSE
chr1214813487AG0.00027CENPF+FALSE
chr126774224AG0.00349DHDDS+TRUEAluSz6SINE,Alu
chr315113716TC2.87067E-10RBSN-TRUEAluSz6SINE,Alu
chr6134492482AC0.00108SGK1-FALSE
chr10114209912AG0.00060VTI1A+TRUEAluSx3SINE,Alu
chr12323041TC0.00970MORN1-FALSE
chr146828653TA0.00920NSUN4+FALSE
chr165298791AT0.00242RAVER2+FALSE
chr642047426AG0.00676TAF8+TRUEAluSz6SINE,Alu
chr1213069783AG0.00600FLVCR1+FALSE
chr3141668922TC0.00937TFDP2-TRUEAluSzSINE,Alu
chr12125267857TC0.00702SCARB1-TRUEFRAMSINE,Alu
chr135650014CA0.00012SFPQ-FALSE
chr110518921CT0.00398.FALSEAluSx3SINE,Alu
chr247129284AG0.00327MCFD2-FALSE
chr263817855CG0.00096MDH1+FALSE
chr11597356GC0.00995CDK11B,SLC35E2B-FALSE
chr5176883676AT0.00456DBN1-FALSE(A)nSINE,Alu
chr1145284134GC0.00203NBPF20,NOTCH2NL+FALSE(TG)nSINE,Alu
chr4119555142AG4.95460E-05LOC729218+FALSE
chr2190636411CG0.00870ORMDL1-FALSE
chr2046284868AT0.00681NCOA3+FALSE
chr1648386442AG0.00824LONP2,MIR5095+TRUEAluSz6SINE,Alu
chr132373837GT0.00068PTP4A2-FALSE(T)nSINE,Alu
chr1541590973AG1.61675E-06OIP5-AS1+TRUEAluSx1SINE,Alu
chr1590375419TC0.00521C15orf38-AP3S2,AP3S2-TRUEAluJrSINE,Alu
chr1474526952TC0.00019BBOF1,ALDH6A1+,-FALSEAluJoSINE,Alu
chr193053116GC0.00276AES-FALSE
chr1168218574AG0.00898.FALSEAluSzSINE,Alu
chr1256345408TG0.00885DGKA+FALSE
chr398518155AT0.00777DCBLD2-FALSE
chr291843471CT0.00095LOC654342-FALSE
chr224227417AG0.00831.FALSEAluScSINE,Alu
chr4247533AG0.00972ZNF876P+FALSE
chr556177846GC0.00952MAP3K1+FALSE
chr19331227AG0.00181H6PD+TRUEAluSxSINE,Alu
chr7129472357AG0.00287UBE2H-FALSE
chr255452458GT0.00113CLHC1-FALSE

Differential Expression Gene Analysis