Dataset Overview
RBPMETTL14
Knock-MethodsiRNA
RBP FamilyMT-A70
Biosample NameHEK293
Tissue TypeKidney
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceGEO
Profile IDGSE56010
PlatformGPL11154
Pubmed ID25719671

METTL14 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of METTL14
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of METTL14


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr199673275TC0.00081.FALSETigger1SINE,Alu
chr452888499GA0.00366SGCB-FALSE
chr1047221465TC0.00201.FALSEAluJbSINE,Alu
chr744918736TC4.05417E-05PURB-TRUEAluSgSINE,Alu
chr1689623607AG0.00915SPG7+FALSE
chr193616202TC0.00194TMED5-FALSE
chr1201846635AT0.00293IPO9+FALSE(CA)nSINE,Alu
chr7105162638GC0.00155PUS7-FALSE
chr5130538043AG0.00713LYRM7+TRUEAluSpSINE,Alu
chr210270757AT0.00382RRM2+FALSE
chr7156763332AG0.00090NOM1+TRUEAluSxSINE,Alu
chr178414334CA0.00702FUBP1-FALSEA-richSINE,Alu
chr136068052GT1.69686E-12PSMB2-FALSEL1ME4bSINE,Alu
chr286731654GA0.00931CHMP3,RNF103-CHMP3-FALSEAluJrSINE,Alu
chr116932429CG0.00221NBPF1-FALSEL1MC2SINE,Alu
chr1220231347TC0.00963RNU5F-1,BPNT1+,-FALSEAluYSINE,Alu
chr1013320111GT0.00571PHYH-FALSE
chr2224622277TC0.00138AP1S3-TRUEAluSx1SINE,Alu
chr125663918GA0.00951RSRP1-FALSE
chr537291508TC0.00430.FALSEAluSx3SINE,Alu
chr534906661TC9.12853E-06RAD1-TRUEAluJoSINE,Alu
chr315112612TC0.00634RBSN-TRUEAluSq2SINE,Alu
chr4155457051AT0.00378PLRG1-FALSEL2d2SINE,Alu
chr9133777993GT0.00959FIBCD1-FALSE
chr167874697TC5.54610E-06SERBP1-TRUEAluSx3SINE,Alu
chr1628296456TC0.00772.FALSEAluJbSINE,Alu
chr116932495AC0.00199NBPF1-FALSEL1MC2SINE,Alu
chr2101622889TA0.00022RPL31+FALSE
chr237328027TC0.00026.FALSE
chr366430372TA0.00300LRIG1-FALSE
chr170728523AG0.00051ANKRD13C-FALSE
chr171531596AG1.07667E-05ZRANB2-AS1,ZRANB2+,-FALSE
chr176227022AG0.00035ACADM+FALSE
chr19162348TC0.00359.FALSEAluSxSINE,Alu
chr1120162442TC0.00065ZNF697-FALSE
chr1206579936AG0.00424SRGAP2+FALSE
chr119586532AG7.13982E-05MRTO4+TRUEAluSzSINE,Alu
chr1376378459TC0.00239LMO7+FALSE
chr1193466866GT0.00559MIR1304-FALSEAluJrSINE,Alu
chr1120695197GA2.17750E-05.FALSE
chr237328097TC3.71887E-07.FALSE
chr314986098TC0.00996FGD5-AS1-TRUEFLAM_CSINE,Alu
chr7131241052AG0.00663PODXL-FALSE(GGCGAC)nSINE,Alu
chr179356400CT0.00714ADGRL4-FALSE
chr1160965379TC0.00081F11R-TRUEAluScSINE,Alu
chr1690037828GA0.00029CENPBD1-FALSETigger12SINE,Alu
chr224225509AG0.00132.FALSEAluSq2SINE,Alu
chr155316322AG0.00266DHCR24-FALSE
chr119934893CA0.00171MINOS1,MINOS1-NBL1,RPS14P3+FALSE
chr1264842925AG0.00345.FALSEAluSzSINE,Alu
chr1431916783TC3.40362E-05LOC101927124,DTD2+,-FALSEAluSc8SINE,Alu
chr146828460CT0.00393NSUN4+FALSE
chr1475202704AG2.33511E-06FCF1+TRUEAluScSINE,Alu
chr5125880589TC0.00122ALDH7A1-FALSE
chr1742113064AG0.00014LSM12-FALSE(A)nSINE,Alu
chr117299387TA0.00941CROCC+FALSE
chr138155698GT0.00368C1orf109-FALSEAluSx1SINE,Alu
chr1590819579AG0.00933.FALSEAluSxSINE,Alu
chr1114940209GT5.13716E-05TRIM33-FALSE(T)nSINE,Alu
chr2219433597GA0.00328CNOT9+FALSE
chr3195393406CT0.00690SDHAP2+FALSE
chr286251114TC0.00709.FALSEAluSxSINE,Alu
chr1205687344CT0.00633NUCKS1-FALSE(T)nSINE,Alu
chr477057501AG0.00547NUP54-FALSE
chr119953120GA0.00024MINOS1,MINOS1-NBL1+FALSE
chr5102345546AC0.00463PAM+FALSE
chr12133298019AG2.77684E-05PGAM5+TRUEAluJoSINE,Alu
chr16282236TC0.00388ICMT-TRUEAluSzSINE,Alu
chr126755643AG0.00728LIN28A+FALSEAluScSINE,Alu
chr3133307642TG0.00523CDV3+FALSE(TT)nSINE,Alu
chr5125961447AG0.00563PHAX+TRUEAluSz6SINE,Alu
chr2242512736GC0.00492BOK+FALSE
chr1941220529CT0.00175COQ8B-FALSE
chr133149443AG2.90388E-05SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr1939982631AG0.00316TIMM50+TRUEAluJrSINE,Alu
chr352109841TC7.35943E-05POC1A-FALSE
chr7920724AG0.00328GET4+TRUEAluSx1SINE,Alu
chr1590819655AG0.00174.FALSEAluSxSINE,Alu
chr1148558269AG0.00538NBPF15+FALSEAluJbSINE,Alu
chr348787684TC0.00813PRKAR2A-TRUEAluSpSINE,Alu
chr9136335345GA0.00490CACFD1+FALSE(TG)nSINE,Alu
chr1256215103AT0.00353DNAJC14-FALSE
chr340503557TC0.00487RPL14+FALSE
chr110518734TC0.00249.FALSEAluSx1SINE,Alu
chr110517314TC0.00073.FALSEAluJrSINE,Alu
chr19162247TC0.00549.FALSEAluSxSINE,Alu
chr572876776CA0.00875UTP15+FALSE
chr631626580GA0.00291.FALSE
chr1474431191AG0.00670ENTPD5-FALSE
chr1023408278CT0.00042MSRB2+FALSE
chr154412181TC0.00524LRRC42+FALSE
chr16583592TC0.00939NOL9-TRUEAluSqSINE,Alu
chr154571491AG0.00538TCEANC2+TRUEAluScSINE,Alu
chr310290507GC0.00367TATDN2+FALSE
chr6149912307AG0.00026.FALSEAluScSINE,Alu
chr110517290TC0.00366.FALSEAluJrSINE,Alu
chr8144940792GC9.20360E-05EPPK1-FALSE
chr1563616881GA0.00026CA12-FALSE
chr3100428460GC5.60949E-08TFG+FALSE
chr1117530477GA0.00223PTGFRN+FALSE
chr348787094TC0.00518PRKAR2A-TRUEAluSx3SINE,Alu
chr116889624TC0.00614NBPF1-TRUE
chr352288956AT0.00042WDR82-FALSE
chr194423353GA0.00057CHAF1A+FALSEGA-richSINE,Alu
chr105499824AG0.00070NET1+FALSE
chr825272447AT0.00770DOCK5+FALSE
chr1115313038GA0.00144SIKE1-FALSE
chr1565442483TC0.00523CLPX-TRUEAluSg4SINE,Alu
chr1424760808CT0.00203DHRS1-FALSE
chr223865260TC0.00262KLHL29+FALSE
chr274333232CT0.00274TET3+FALSE
chr7128144035AG0.00054.FALSEAluSq2SINE,Alu
chr1120611964GC0.00077NOTCH2-FALSE
chr146075191CA0.00056NASP+FALSEA-richSINE,Alu
chr744841791CT0.00182PPIA+FALSE
chr116889014CT0.00722NBPF1-FALSE
chr119542464TC0.00736LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr6160526905CA0.00268IGF2R+FALSE
chr132096265AG0.00208PEF1-FALSE
chr611577085CT1.34362E-05TMEM170B+FALSE
chr2203742141TC0.00044.FALSEAluJbSINE,Alu
chr1689627988GT5.83717E-06RPL13+FALSE
chr570248477TA0.00163SMN1,SMN2+FALSEL1MC5aSINE,Alu
chr1942375586AG0.00016.FALSEAluSxSINE,Alu
chr638140503CT0.00065BTBD9-FALSE
chr398517013TC1.12976E-12DCBLD2-FALSE
chr3156258295TC0.00096SSR3-TRUEAluYk3SINE,Alu
chr5170837887TA0.00401NPM1+FALSE
chr1226333558AC0.00052ACBD3-FALSE(CAAAA)nSINE,Alu
chr3124948049TC0.00069ZNF148-TRUE
chr110520692TC0.00973DFFA-TRUEAluSc8SINE,Alu
chr310192642AG0.00714VHL+TRUEAluSx1SINE,Alu
chr310285030GA0.00384IRAK2+FALSE
chr13654747CA0.00691TP73-AS1-FALSE
chr110520076TC0.00075.FALSEAluSxSINE,Alu
chr119543282TC0.00020LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr110520984GT0.00305DFFA-FALSEAluYSINE,Alu
chr2217366534AG0.00733.FALSEAluSzSINE,Alu
chr1145695329AG0.00400NBPF20,NBPF10+FALSEAluSzSINE,Alu
chr642855101AG0.00329RPL7L1+TRUEAluSpSINE,Alu
chr2206986949TC0.00693.FALSEAluJrSINE,Alu
chr122419433TG0.00156CDC42+FALSE
chr1379188534TA0.00698RNF219-AS1,RNF219+,-FALSE
chr311598816CA0.00118ATG7,VGLL4+,-FALSE
chr124935369AG0.00454NCMAP+TRUEAluJbSINE,Alu
chr119543459TC0.00074LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr1104097685CT0.00721RNPC3,AMY2B+FALSE
chr353260620TG0.00069TKT-FALSE
chr194335332GT0.00973DNTTIP2-FALSE
chr1533064474GC0.00653FMN1-FALSE
chr11721936GA0.00731GNB1-FALSE
chr285554792CA0.00634TGOLN2-FALSE
chr121806710TG0.00194NBPF3+FALSE
chr3183889337AT3.46641E-05DVL3+FALSE
chr1110023610GA0.00636SYPL2+FALSE
chr199673005TC0.00017.FALSEAluSx3SINE,Alu
chr126608012CA0.00564SH3BGRL3+FALSE
chr1179044110AG5.39593E-06FAM20B+TRUEAluSxSINE,Alu
chr1669338754TC0.00210SNTB2+FALSEAluJrSINE,Alu
chr744918672TC0.00150PURB-TRUEAluSgSINE,Alu
chr7128142833AG6.82570E-05METTL2B+TRUEAluSx1SINE,Alu
chr786816663AG0.00103DMTF1+TRUEAluJrSINE,Alu
chr133066859AG0.00403ZBTB8A+TRUEAluSq4SINE,Alu
chr3196670094GC0.00669NCBP2-AS2+FALSE
chr1100657328AG0.00682DBT-FALSE(AC)nSINE,Alu
chr19163839AG0.00237.FALSE
chr3196658640CT0.00444SENP5+FALSE
chr1169811639GC0.00134C1orf112+FALSE
chr125889176CT3.50303E-06LDLRAP1+FALSE
chr1478390880TC0.00050ADCK1+FALSE
chr145976261TA0.00018MMACHC+FALSE
chr1162299945AC0.00314AHNAK-FALSE
chr127202901TC0.00224.FALSEAluSq2SINE,Alu
chr124022437AG0.00342RPL11+FALSE
chr1145273431AG0.00203NBPF20,NOTCH2NL+FALSE
chr1610625101TC0.00804EMP2-TRUEAluSx3SINE,Alu
chr5177576460CT0.00635.FALSE
chr1988503AT0.00141AGRN+FALSE
chr5150647744AG0.00036GM2A+TRUEAluScSINE,Alu
chr11647814TC7.10450E-06CDK11B,CDK11A-FALSE
chr549692280TC9.73531E-05EMB-FALSEL2cSINE,Alu
chr2174828621AC0.00315SP3-FALSE
chr4165998692TC0.00568TMEM192-TRUEAluSgSINE,Alu
chr6116256595CA5.71236E-05.FALSE
chr237506939AG0.00119PRKD3-FALSE
chr127434251GA0.00504SLC9A1-FALSE
chr417803604TC0.00174DCAF16-TRUEAluYSINE,Alu
chr410076658TC6.66134E-16WDR1-FALSE
chr2130795675CT0.00578FAR2P1-FALSE
chr339137789GA0.00579WDR48+FALSE
chr1746025078AG0.00021PNPO+TRUEAluScSINE,Alu
chr1089005496TG0.00138NUTM2A-AS1-FALSEMSTB1SINE,Alu
chr140537923GA0.00609CAP1+FALSE(A)nSINE,Alu
chr344791454AT3.12862E-05KIAA1143-FALSEAluJrSINE,Alu
chr1145512166TA0.00736NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr116889414TC0.00012NBPF1-TRUEL1MC4SINE,Alu
chr2201842492TC0.00107FAM126B-TRUEAluJbSINE,Alu
chr1396506664AG5.36176E-05UGGT2-FALSE
chr2196602326TG0.00503SLC39A10+FALSE
chr1114515903CT0.00169HIPK1+FALSE
chr1145511998AG0.00675NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr468484330GA0.00131UBA6-FALSE
chr119586532AG0.00166MRTO4+TRUEAluSzSINE,Alu
chr439550558TC0.00441UGDH-AS1,SMIM14+,-FALSEAluSx1SINE,Alu
chr116927391TC0.00110NBPF1-FALSE
chr914764CT0.00491WASH1-FALSE
chr116890639CT8.47214E-05NBPF1-FALSE
chr285776832CT0.00514GGCX-FALSE
chr1145513098AG0.00514NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr162553869AT0.00089TBC1D24+FALSE
chr4188925184GA0.00032ZFP42+FALSE
chr1179044100AG0.00219FAM20B+TRUEAluSxSINE,Alu
chr1120612037TG0.00044NOTCH2-FALSE(CGC)nSINE,Alu
chr1942376872AG0.00647.FALSEAluSpSINE,Alu
chr1144821888CG0.00093NBPF20,NBPF9+FALSE
chr146159809TA0.00605TMEM69+FALSE
chr255516908AG0.00016CCDC88A-FALSE(GA)nSINE,Alu
chr11594977TC0.00487CDK11B,SLC35E2B-TRUEAluSgSINE,Alu
chr2025428308AG0.00185GINS1+TRUEAluSzSINE,Alu
chr299812311AG0.00016MRPL30+TRUEAluSxSINE,Alu
chr617557412CT0.00986CAP2+FALSE
chr11309885AG0.00010AURKAIP1-FALSE
chr1165404870CT0.00160PCNX3+FALSE
chr136068295TC0.00058PSMB2-TRUEAluScSINE,Alu
chr153288894AG8.27269E-06ZYG11B+TRUEAluJoSINE,Alu
chr162380298GA0.00025PATJ+FALSE
chr330735330GT0.00402TGFBR2+FALSE
chr16584872TC9.65243E-06NOL9-TRUEAluYk2SINE,Alu
chr537290554TC0.00010.FALSEAluSzSINE,Alu

Differential Expression Gene Analysis