Dataset Overview
RBP
TRIM25
Knock-Method
siRNA
RBP Family
Non-canonical_RBP
Biosample Name
T47D
Tissue Type
Breast
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
GEO
Profile ID
GSE79586
Platform
GPL167891
Pubmed ID
28813674
TRIM25 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of TRIM25
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
AACS
19.16
15.56
-0.26357
0.01292
0.09113
AARD
1.16
0.31
-1.51797
0.00020
0.00393
ABCA12
25.06
35.95
0.50908
8.09966E-08
4.76911E-06
ABCA3
41.11
30.02
-0.42044
6.98001E-05
0.00167
ABCA5
9.96
7.54
-0.35634
0.01221
0.08750
ABCA7
2.9
1.75
-0.72420
0.00106
0.01460
ABCC11
68.56
88.81
0.38740
0.00027
0.00499
ABCC12
3.81
2.16
-0.49645
0.02927
0.15584
ABCC3
3.67
2.25
-0.99757
0.00046
0.00762
ABCC5
25.09
28.13
0.20840
0.03413
0.17068
Showing 1 to 10 of 3,189 entries
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Function Analysis of Target Genes of TRIM25
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AASDHPPT
105961283_105961405_105950193_105950419_105962042_105962186
0.00008
0.375
DataSet_02_111
View details
ABCB7
74332720_74332807_74318776_74318896_74375939_74376117
0.00246
0.4
DataSet_02_111
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ABCD4
74756729_74756821_74756003_74756222_74756993_74757155
0.00027
0.834
DataSet_02_111
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ABCF1
30545185_30545232_30539152_30539337_30545594_30545690
0.00062
-0.275
DataSet_02_111
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ABHD11
73151258_73151440_73150423_73151021_73151891_73152065
0.00764
0.3
DataSet_02_111
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ABHD11
73152205_73152402_73151897_73152065_73152657_73152793
0.00041
-0.619
DataSet_02_111
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ABHD11
73152205_73152472_73151975_73152065_73152657_73152713
0.00097
-0.422
DataSet_02_111
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ABHD18
128910875_128910976_128905493_128905578_128930074_128930112
0.00236
-0.416
DataSet_02_111
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ABI1
27047990_27048167_27044583_27044670_27054146_27054247
0.00327
0.334
DataSet_02_111
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AC004832.3
30823157_30823390_30822704_30822832_30824448_30824974
0.00584
0.231
DataSet_02_111
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Showing 1 to 10 of 525 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABHD18
128910875_128910976_128922870_128922915_128905493_128905578
0.00003
-0.744
DataSet_02_111
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ABI1
27044583_27044670_27047990_27048164_27040526_27040712
0.00320
0.367
DataSet_02_111
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ADAM15
155033890_155033965_155034379_155034451_155033238_155033308
0.00175
0.166
DataSet_02_111
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ADAM15
155033890_155033965_155034379_155034593_155033238_155033308
0.00424
0.251
DataSet_02_111
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ANKMY1
241448764_241448872_241451277_241451418_241446976_241447108
0.00003
-0.75
DataSet_02_111
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APOD
195309487_195309610_195309937_195310073_195306209_195306366
0.00145
-0.666
DataSet_02_111
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BCL2L13
18165979_18166087_18185008_18185152_18138427_18138598
0.00163
-0.4
DataSet_02_111
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BCL7B
72954211_72954382_72957877_72957974_72952263_72952343
0.00158
0.502
DataSet_02_111
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BTN2A2
26385242_26385590_26388240_26388522_26384019_26384143
0.00363
-0.25
DataSet_02_111
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C17orf62
80404498_80404572_80405455_80405497_80403739_80403836
0.00482
0.494
DataSet_02_111
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Showing 1 to 10 of 40 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AC005562.1
28958772_28958945_28958772_28958913_28960115_28960408
0.00238
-0.179
DataSet_02_111
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AKR1E2
4889339_4889491_4889339_4889422_4889679_4890254
0.00056
-0.5
DataSet_02_111
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ALG13
110925359_110925522_110925359_110925463_110928192_110928331
0.00027
0.834
DataSet_02_111
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ANXA2
60644577_60644675_60644581_60644675_60643922_60644018
0.00452
-0.218
DataSet_02_111
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ARL6IP4
123465675_123465846_123465675_123465813_123466141_123466426
0.00277
0.279
DataSet_02_111
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ASAH1
17941489_17942489_17942184_17942489_17933049_17933096
0.00000
-0.834
DataSet_02_111
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ATG4C
63249805_63249944_63249805_63249896_63269389_63269533
0.00282
-0.295
DataSet_02_111
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ATG4D
10657514_10657758_10657514_10657747_10657864_10657929
0.00348
0.646
DataSet_02_111
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C6orf48
31802684_31802977_31802684_31802834_31803187_31803228
0.00763
-0.104
DataSet_02_111
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CBX1
46153350_46153540_46153362_46153540_46152367_46152462
0.00061
-0.465
DataSet_02_111
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Showing 1 to 10 of 80 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACIN1
23533313_23533466_23533313_23533430_23533563_23533694
0.00000
-0.936
DataSet_02_111
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ACIN1
23533563_23533697_23533563_23533694_23535174_23535217
0.00583
-0.092
DataSet_02_111
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AKAP10
19861326_19861884_19861326_19861880_19866152_19866335
0.00003
0.827
DataSet_02_111
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AKAP10
19866152_19866335_19866152_19866279_19871726_19871774
0.00155
-0.667
DataSet_02_111
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ALKBH1
78141998_78142192_78141998_78142137_78146222_78146313
0.00373
0.112
DataSet_02_111
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ANKRD11
89383340_89383486_89383340_89383483_89484691_89484776
0.00459
0.236
DataSet_02_111
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ARL16
79649063_79649705_79649063_79649179_79650042_79650156
0.00267
-0.233
DataSet_02_111
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ARL6IP4
123466117_123466426_123466141_123466426_123465675_123465813
0.00515
0.273
DataSet_02_111
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ATXN2L
28848068_28848558_28848071_28848558_28847253_28847443
0.00204
-0.157
DataSet_02_111
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B4GALT7
177034283_177034528_177034302_177034528_177031179_177031542
0.00000
0.714
DataSet_02_111
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABCF3
183905184_183905549_183905184_183905231_183905451_183905549
0.00816
0.213
DataSet_02_111
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AC026412.1
1632758_1633021_1632758_1632866_1632959_1633021
0.00222
-0.357
DataSet_02_111
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ADCK5
145616779_145617066_145616779_145616911_145616982_145617066
0.00916
0.25
DataSet_02_111
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ADD1
2910241_2911158_2910241_2910331_2911065_2911158
0.00888
0.183
DataSet_02_111
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AMZ2P1
62968871_62969635_62968871_62969045_62969359_62969635
0.00007
-0.622
DataSet_02_111
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ANXA5
122617735_122618130_122617735_122617779_122618017_122618130
0.00024
0.354
DataSet_02_111
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ARL6IP4
123465675_123466426_123465675_123465813_123466141_123466426
0.00411
0.269
DataSet_02_111
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ATG4D
10657514_10657929_10657514_10657758_10657864_10657929
0.00068
-0.65
DataSet_02_111
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ATXN2L
28847253_28848558_28847253_28847443_28848071_28848558
0.00036
-0.136
DataSet_02_111
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B4GALNT3
661632_663149_661632_661694_662359_663149
0.00154
-0.384
DataSet_02_111
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
19934758
C
G
1.75422E-05
MINOS1,MINOS1-NBL1,RPS14P3
+
FALSE
chr1
145511991
A
G
0.00044
NBPF20,NBPF10,RBM8A,GNRHR2
+,-
FALSE
AluY
SINE,Alu
chr1
113511341
A
G
0.00283
.
FALSE
AluY
SINE,Alu
chr1
197477932
C
T
0.00488
DENND1B
-
FALSE
chr1
19542433
T
C
0.00076
LOC101927895,EMC1
+,-
FALSE
AluSz
SINE,Alu
chr1
53291408
A
G
0.00931
ZYG11B
+
TRUE
AluJr
SINE,Alu
chr1
178447798
T
C
2.92578E-05
RASAL2
+
FALSE
chr1
117529752
C
A
0.00024
PTGFRN
+
FALSE
chr1
10044272
A
G
0.00737
NMNAT1
+
TRUE
AluSx1
SINE,Alu
chr1
53292875
G
T
8.43181E-07
ZYG11B
+
FALSE
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression