Dataset Overview
RBP
YTHDF1
Knock-Method
shRNA
RBP Family
YTH
Biosample Name
HCT116
Tissue Type
Intestin
Biosample Type
Cell line
# of Control
1
# of Treat
2
Species
Human
Data Source
GEO
Profile ID
GSE136664
Platform
GPL20795
Pubmed ID
N.A.
YTHDF1 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of YTHDF1
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
ABHD14A-ACY1
0.0
1.69
8.11190
0.00011
0.13259
AC005523.2
1.2
6.17
2.37819
4.21366E-05
0.06486
AC007347.1
0.0
2.1
8.13874
6.48925E-05
0.08879
AC013268.2
0.0
3.45
8.92388
3.12812E-05
0.05503
AHNAK
64.83
50.78
0.80531
0.04397
1.00000
AHNAK2
4.56
11.65
1.18259
0.02617
1.00000
ARPC3
148.57
276.21
0.83015
0.03589
1.00000
ATF3
10.65
31.91
1.39558
0.03033
1.00000
ATF7IP2
0.23
1.94
2.28828
0.02500
1.00000
AUH
10.09
22.16
1.29900
0.01228
1.00000
Showing 1 to 10 of 119 entries
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Function Analysis of Target Genes of YTHDF1
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AAAS
53701628_53701713_53701239_53701497_53701835_53701917
0.00076
0.39
DataSet_02_123
View details
AAMDC
77566390_77566528_77553524_77553674_77580767_77580863
0.00008
0.51
DataSet_02_123
View details
ABCA11P
431234_431300_419603_420762_466363_466490
0.00000
-0.742
DataSet_02_123
View details
ABCA2
139918289_139918292_139917392_139917504_139918594_139918688
0.00001
1.0
DataSet_02_123
View details
ABCC1
16177222_16177399_16173208_16173335_16184261_16184445
0.00006
0.3
DataSet_02_123
View details
ABCC1
16180680_16180848_16173208_16173335_16184261_16184445
0.00720
-0.193
DataSet_02_123
View details
ABCC1
16199256_16199317_16196539_16196574_16200594_16200730
0.00060
-0.588
DataSet_02_123
View details
ABHD11
73151258_73151440_73150423_73151021_73151891_73152065
0.00025
0.76
DataSet_02_123
View details
ABHD11
73151258_73151550_73150865_73151021_73151891_73152065
0.00015
0.542
DataSet_02_123
View details
ABHD11
73152205_73152402_73151897_73152065_73152657_73152793
0.00002
0.455
DataSet_02_123
View details
Showing 1 to 10 of 1,601 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABI1
27044583_27044670_27047990_27048167_27040526_27040712
0.00409
-0.257
DataSet_02_123
View details
AC087632.1
64658184_64658274_64668941_64669104_64592517_64592922
0.00599
0.05
DataSet_02_123
View details
ACADM
76194085_76194173_76198328_76198426_76190390_76190502
0.00395
-0.186
DataSet_02_123
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AFMID
76200908_76200981_76201520_76201599_76198783_76198832
0.00004
-0.86
DataSet_02_123
View details
ANXA2
60682411_60682516_60688478_60688626_60678226_60678285
0.00482
-0.19
DataSet_02_123
View details
APEH
49713488_49713652_49713810_49713948_49713323_49713399
0.00022
0.426
DataSet_02_123
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APOPT1
104045707_104045828_104047905_104047993_104040443_104040507
0.00656
0.189
DataSet_02_123
View details
ARIH2
48960180_48960244_48964894_48965246_48956253_48956431
0.00681
0.184
DataSet_02_123
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ARMC10
102727315_102727384_102732923_102733100_102727076_102727211
0.00007
-0.282
DataSet_02_123
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BRPF3
36189944_36190042_36193043_36193141_36185693_36185787
0.00390
-0.522
DataSet_02_123
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Showing 1 to 10 of 98 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AC026412.1
1632758_1633021_1632959_1633021_1602805_1602850
0.00261
0.229
DataSet_02_123
View details
AC087380.1
5526580_5526882_5526798_5526882_5368105_5368140
0.00018
0.131
DataSet_02_123
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ACAD9
128598471_128598860_128598471_128598684_128603495_128603589
0.00004
0.131
DataSet_02_123
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ACADVL
7127131_7127194_7127131_7127177_7127286_7127388
0.00000
-1.0
DataSet_02_123
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ADCY9
4043349_4043511_4043406_4043511_4042146_4042364
0.00812
-0.28
DataSet_02_123
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AFG3L1P
90050938_90051025_90050938_90051007_90057273_90057411
0.00010
-0.626
DataSet_02_123
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ANAPC5
121769029_121769231_121769149_121769231_121768385_121768475
0.00166
0.5
DataSet_02_123
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APRT
88877904_88878064_88877957_88878064_88876477_88876556
0.00371
0.322
DataSet_02_123
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ARHGEF5
144059750_144062916_144059750_144059946_144063447_144063505
0.00058
-0.375
DataSet_02_123
View details
ARIH1
72873071_72873332_72873071_72873218_72874415_72874528
0.00001
-0.195
DataSet_02_123
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Showing 1 to 10 of 232 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABCA2
139917392_139918292_139917392_139917504_139918594_139918688
0.00003
1.0
DataSet_02_123
View details
ABLIM1
116207638_116207785_116207638_116207779_116211382_116211430
0.00179
-0.209
DataSet_02_123
View details
AC020915.1
58823393_58823828_58823531_58823828_58817453_58817582
0.00644
-0.066
DataSet_02_123
View details
AC020915.6
58758076_58758160_58758111_58758160_58757666_58757793
0.00000
-0.551
DataSet_02_123
View details
ACADVL
7127798_7127871_7127802_7127871_7127639_7127712
0.00077
0.387
DataSet_02_123
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ACIN1
23533313_23533466_23533313_23533430_23533563_23533694
0.00059
-0.288
DataSet_02_123
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ACOT8
44482561_44482623_44482561_44482618_44483797_44483931
0.00000
-0.936
DataSet_02_123
View details
AFG3L1P
90045709_90046744_90046649_90046744_90045217_90045286
0.00060
-0.096
DataSet_02_123
View details
AGTRAP
11805986_11806280_11806044_11806280_11805859_11805894
0.00000
-1.0
DataSet_02_123
View details
AGTRAP
11805986_11806280_11806183_11806280_11805859_11805894
0.00945
0.477
DataSet_02_123
View details
Showing 1 to 10 of 334 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AC005324.4
15603361_15603680_15603361_15603482_15603586_15603680
0.00002
-0.377
DataSet_02_123
View details
ACAA1
38167652_38168191_38167652_38167832_38168000_38168191
0.00908
0.5
DataSet_02_123
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ACAD8
134129501_134131073_134129501_134129639_134130937_134131073
0.00046
0.634
DataSet_02_123
View details
ACADVL
7124084_7124377_7124084_7124149_7124242_7124377
0.00030
0.156
DataSet_02_123
View details
ACADVL
7127131_7127388_7127131_7127177_7127286_7127388
0.00042
-0.425
DataSet_02_123
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ACADVL
7127131_7127388_7127131_7127194_7127286_7127388
0.00000
0.834
DataSet_02_123
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ACADVL
7127639_7127871_7127639_7127712_7127802_7127871
0.00043
0.74
DataSet_02_123
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ACP2
47269191_47269684_47269191_47269278_47269588_47269684
0.00002
-0.417
DataSet_02_123
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AHSA2
61412636_61413632_61412636_61412753_61413580_61413632
0.00000
-1.0
DataSet_02_123
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AKT1
105239214_105239716_105239214_105239330_105239587_105239716
0.00025
0.459
DataSet_02_123
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
36068369
T
C
0.00404
PSMB2
-
TRUE
AluSc
SINE,Alu
chr1
6283306
T
C
0.00275
ICMT
-
TRUE
AluSx3
SINE,Alu
chr1
178444613
T
G
0.00630
RASAL2
+
FALSE
chr1
19542458
T
C
7.14858E-05
LOC101927895,EMC1
+,-
FALSE
AluSz
SINE,Alu
chr1
31905886
C
A
0.00702
SERINC2
+
FALSE
chr1
7980667
T
C
0.00584
TNFRSF9
-
TRUE
AluJb
SINE,Alu
chr1
10519947
T
C
0.00184
.
FALSE
AluJr
SINE,Alu
chr1
145513098
A
G
0.00171
NBPF20,NBPF10,RBM8A,GNRHR2
+,-
FALSE
AluSz6
SINE,Alu
chr1
1419768
A
G
0.00189
ATAD3B
+
TRUE
AluYk2
SINE,Alu
chr1
31732892
G
A
0.00408
SNRNP40
-
FALSE
Showing 1 to 10 of 441 entries
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression