Dataset Overview
RBP
DDX6
Knock-Method
shRNA
RBP Family
DEAD
Biosample Name
hESCs
Tissue Type
Embryo
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
GEO
Profile ID
GSE112383
Platform
GPL11154
Pubmed ID
31588046
DDX6 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of DDX6
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A1BG-AS1
1.77
1.15
-0.72502
0.00504
0.01191
A2ML1
1.06
1.67
1.25175
1.15007E-09
8.07414E-09
AAAS
27.32
21.04
-0.45776
1.71163E-08
1.04369E-07
AACS
9.87
12.07
0.26095
0.00158
0.00419
AADAT
3.92
5.05
0.25053
0.04083
0.07452
AAED1
3.3
2.37
-0.40375
0.03079
0.05825
AAK1
2.97
5.45
0.69308
9.09636E-07
4.33841E-06
AAMDC
11.88
9.56
-0.36081
0.03495
0.06505
AARD
0.89
0.75
-0.59544
0.03310
0.06208
AARS
70.95
99.76
0.42487
3.54964E-08
2.08445E-07
Showing 1 to 10 of 8,969 entries
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Function Analysis of Target Genes of DDX6
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABHD11
73151258_73151550_73150865_73151021_73151891_73152065
0.00000
-1.0
DataSet_02_25
View details
AC009446.1
72608175_72608268_72587611_72587770_72614449_72614670
0.00006
-0.081
DataSet_02_25
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AC106864.1
113568570_113568623_113567878_113568124_113569809_113569855
0.00000
-0.048
DataSet_02_25
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AKT1
105259463_105259641_105258934_105259059_105261820_105261841
0.00477
0.149
DataSet_02_25
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AL117339.5
38383858_38384152_38383295_38383418_38384465_38384557
0.00766
-0.317
DataSet_02_25
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ALG13
110964830_110964939_110963322_110963398_110967025_110967109
0.00204
-0.166
DataSet_02_25
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ANGEL1
77270717_77270758_77270128_77270255_77272758_77272858
0.00018
-0.186
DataSet_02_25
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ANO6
45621950_45622056_45609902_45610174_45664244_45664307
0.00000
-0.834
DataSet_02_25
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BCL11B
99697681_99697894_99635623_99642532_99723807_99724176
0.00001
0.625
DataSet_02_25
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BHLHB9
102002744_102002839_101975884_101976019_102003626_102003809
0.00004
0.734
DataSet_02_25
View details
Showing 1 to 10 of 86 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
CADM1
115069125_115069158_115080293_115080377_115049363_115049495
0.00000
-0.492
DataSet_02_25
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CROCCP3
16812920_16813156_16816179_16816286_16812063_16812160
0.00181
-0.625
DataSet_02_25
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DDX46
134124905_134124954_134125795_134125912_134124202_134124281
0.00010
-0.496
DataSet_02_25
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GEMIN2
39594195_39594240_39597483_39597552_39591633_39591747
0.00241
-0.515
DataSet_02_25
View details
SPATS2L
201236831_201236974_201248589_201248740_201194153_201194203
0.00001
-0.522
DataSet_02_25
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Showing 1 to 5 of 5 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
COL27A1
116994101_116994146_116994101_116994138_116997878_116997932
0.00079
0.581
DataSet_02_25
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DHX29
54578943_54579639_54579030_54579639_54577199_54577343
0.00780
0.084
DataSet_02_25
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ESPN
6508700_6509151_6508700_6508862_6511662_6511808
0.00226
0.367
DataSet_02_25
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KLC1
104145720_104145882_104145720_104145855_104166991_104167064
0.00036
-0.308
DataSet_02_25
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KLHDC8B
49210068_49210578_49210068_49210234_49211671_49211836
0.00798
-0.225
DataSet_02_25
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NCBP3
3727086_3728344_3728235_3728344_3725246_3725346
0.00587
0.176
DataSet_02_25
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RPL41
56510558_56510714_56510558_56510613_56510972_56510995
0.00589
-0.205
DataSet_02_25
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RRAS2
14379783_14380031_14379802_14380031_14317313_14317401
0.00000
0.788
DataSet_02_25
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SLC2A6
136338536_136339210_136339101_136339210_136338226_136338372
0.00014
0.333
DataSet_02_25
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SNHG8
119199863_119200292_119199863_119199947_119200543_119200586
0.00104
-0.417
DataSet_02_25
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Showing 1 to 10 of 12 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
APEH
49713488_49713948_49713810_49713948_49713323_49713399
0.00050
-0.535
DataSet_02_25
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ATG4D
10657514_10657929_10657864_10657929_10655632_10655806
0.00437
-0.279
DataSet_02_25
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CROCCP2
16946339_16946533_16946339_16946519_16952269_16952500
0.00499
0.259
DataSet_02_25
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DNAJC25
114405118_114405374_114405136_114405374_114393639_114394023
0.00054
-0.614
DataSet_02_25
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FLOT1
30708966_30709481_30708966_30709110_30709568_30709644
0.00983
-0.584
DataSet_02_25
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MYL6
56553370_56553932_56553758_56553932_56552467_56552495
0.00028
-0.417
DataSet_02_25
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PCAT6
202780702_202781041_202780816_202781041_202780089_202780498
0.00404
-0.267
DataSet_02_25
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PDAP1
99001020_99001148_99001020_99001128_99002484_99002576
0.00007
0.172
DataSet_02_25
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PPP6R3
68355412_68355492_68355445_68355492_68343425_68343511
0.00070
-0.46
DataSet_02_25
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RECQL
21654103_21654306_21654103_21654149_21654396_21654603
0.00814
0.183
DataSet_02_25
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Showing 1 to 10 of 16 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACTG1
79478213_79478829_79478213_79478652_79478788_79478829
0.00866
0.533
DataSet_02_25
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B4GALNT4
375638_375956_375638_375773_375846_375956
0.00171
0.135
DataSet_02_25
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BAP1
52436794_52437314_52436794_52436956_52437153_52437314
0.00469
-0.202
DataSet_02_25
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C18orf8
21110192_21110576_21110192_21110261_21110474_21110576
0.00761
0.116
DataSet_02_25
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CAPRIN2
30867892_30869610_30867892_30868015_30869441_30869610
0.00002
0.382
DataSet_02_25
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FAM133B
92206968_92207496_92206968_92206990_92207463_92207496
0.00435
0.3
DataSet_02_25
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LINC00618
97411385_97411731_97411385_97411487_97411574_97411731
0.00049
-0.584
DataSet_02_25
View details
RNF123
49742082_49742619_49742082_49742189_49742514_49742619
0.00002
0.584
DataSet_02_25
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UFD1
19438143_19442353_19438143_19438267_19442324_19442353
0.00672
0.555
DataSet_02_25
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Showing 1 to 9 of 9 entries
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
16892274
A
T
0.00371
NBPF1
-
FALSE
chr1
25655853
A
G
0.00147
RSRP1,RHD
+,-
FALSE
AluSz
SINE,Alu
chr1
1650832
A
G
0.00065
CDK11B,CDK11A
-
FALSE
chr1
24710405
A
G
0.00246
STPG1
-
FALSE
chr1
113672569
A
G
0.00674
.
FALSE
AluJb
SINE,Alu
chr1
27879800
T
G
0.00473
AHDC1
-
FALSE
MIRb
SINE,Alu
chr1
226171400
T
C
0.00359
SDE2
-
TRUE
BC200
SINE,Alu
chr1
10520487
T
C
0.00559
.
FALSE
AluSx1
SINE,Alu
chr1
204525548
A
G
0.00501
MDM4
+
TRUE
AluSz
SINE,Alu
chr1
2333763
G
A
0.00867
RER1
+
FALSE
Showing 1 to 10 of 306 entries
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression