Dataset Overview
RBP
DDX6
Knock-Method
shRNA
RBP Family
DEAD
Biosample Name
hESCs
Tissue Type
Embryo
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
GEO
Profile ID
GSE112383
Platform
GPL11154
Pubmed ID
31588046
DDX6 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of DDX6
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A2M
1.05
0.3
-2.49595
4.18364E-08
6.66236E-07
A4GALT
2.62
4.08
0.56583
0.00316
0.01253
AAAS
26.29
23.78
-0.28535
0.01120
0.03526
AACSP1
0.72
0.38
-0.69143
0.04096
0.09904
AADACL3
0.23
0.98
2.13207
2.49387E-10
6.34399E-09
AAED1
3.3
3.54
-0.34069
0.03145
0.08015
AAK1
2.32
4.41
0.70965
2.64766E-05
0.00022
AARS2
6.36
7.61
0.23260
0.04699
0.11020
AASDH
7.49
6.13
-0.41470
0.00186
0.00806
AASS
164.94
126.04
-0.42199
0.00130
0.00594
Showing 1 to 10 of 6,705 entries
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Function Analysis of Target Genes of DDX6
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABHD18
128922870_128922915_128905493_128905578_128930074_128930153
0.00093
-0.5
DataSet_02_26
View details
AC009446.1
72608175_72608268_72587611_72587770_72614449_72614670
0.00270
-0.053
DataSet_02_26
View details
AC092490.1
8942595_8942859_8940869_8941382_8946900_8946932
0.00734
-0.036
DataSet_02_26
View details
AC093157.1
101538215_101538386_101491433_101491617_101540950_101541272
0.00000
-1.0
DataSet_02_26
View details
AC135178.2
8274626_8275399_8271955_8273704_8279217_8279422
0.00190
-0.383
DataSet_02_26
View details
ACOT8
44472165_44472411_44470364_44470595_44472901_44473059
0.00027
0.834
DataSet_02_26
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ACTR1A
104241757_104241932_104240888_104240929_104242767_104242860
0.00000
1.0
DataSet_02_26
View details
AKT1
105259463_105259641_105258934_105259059_105261820_105261841
0.00320
-0.166
DataSet_02_26
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AL117339.5
38383858_38384152_38383295_38383418_38384465_38384557
0.00249
0.483
DataSet_02_26
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ANO6
45621950_45622056_45609902_45610174_45664244_45664307
0.00000
1.0
DataSet_02_26
View details
Showing 1 to 10 of 112 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ATP8A1
42592827_42592901_42596305_42596379_42590276_42590346
0.00022
0.369
DataSet_02_26
View details
CADM1
115069125_115069158_115080293_115080377_115049363_115049495
0.00001
0.585
DataSet_02_26
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CCT4
62107420_62107529_62110593_62110683_62106003_62106146
0.00000
1.0
DataSet_02_26
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CENPH
68491543_68491618_68492879_68492936_68490473_68490522
0.00243
-0.584
DataSet_02_26
View details
CTDP1
77488906_77489069_77496354_77496521_77477809_77478016
0.00002
-0.4
DataSet_02_26
View details
ECD
74912050_74912179_74914013_74914206_74908033_74908162
0.00444
0.584
DataSet_02_26
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EIF4G3
21324093_21324126_21327691_21327805_21307540_21307720
0.00000
0.669
DataSet_02_26
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MDM2
69208382_69208469_69209407_69209500_69207333_69207408
0.00000
-0.482
DataSet_02_26
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PIGF
46815213_46815318_46818941_46819064_46808423_46808730
0.00735
-0.159
DataSet_02_26
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UBE2C
44443022_44443109_44444028_44444179_44442075_44442103
0.00002
0.58
DataSet_02_26
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
BDNF
27721710_27722035_27721728_27722035_27676439_27680132
0.00121
-0.448
DataSet_02_26
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C7orf49
134853537_134853812_134853720_134853812_134852483_134852559
0.00001
0.38
DataSet_02_26
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MYL6
56553370_56553514_56553370_56553406_56553758_56553932
0.00000
-1.0
DataSet_02_26
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NDUFS5
39491989_39492074_39491989_39492070_39494394_39494612
0.00132
0.348
DataSet_02_26
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NDUFS8
67798209_67798428_67798209_67798344_67799618_67799676
0.00000
-0.875
DataSet_02_26
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RPS19
42364324_42364515_42364324_42364359_42364844_42364915
0.00741
-0.334
DataSet_02_26
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SLC12A7
1076005_1076351_1076252_1076351_1075485_1075605
0.00039
-0.35
DataSet_02_26
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SLC2A6
136338536_136339210_136339101_136339210_136338226_136338372
0.00594
-0.274
DataSet_02_26
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SMARCAL1
217277136_217277371_217277136_217277326_217278578_217278615
0.00033
-0.827
DataSet_02_26
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TRA2A
23561739_23562051_23561972_23562051_23561325_23561459
0.00058
-0.381
DataSet_02_26
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Showing 1 to 10 of 10 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACSL4
108926364_108926895_108926364_108926781_108939372_108939425
0.00068
-0.65
DataSet_02_26
View details
AP001347.1
15515829_15516789_15516077_15516789_15456270_15456465
0.00027
0.834
DataSet_02_26
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BAP1
52440268_52440392_52440268_52440338_52440844_52440923
0.00204
-0.18
DataSet_02_26
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CARMIL2
67690703_67690784_67690736_67690784_67690326_67690548
0.00269
0.302
DataSet_02_26
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CCNJ
97816844_97817004_97816880_97817004_97816457_97816757
0.00271
0.198
DataSet_02_26
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DHPS
12786830_12786956_12786830_12786919_12788104_12788210
0.00764
-0.235
DataSet_02_26
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ECSIT
11618516_11618665_11618516_11618544_11618805_11618863
0.00120
0.5
DataSet_02_26
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EIF4G1
184035534_184035604_184035537_184035604_184035108_184035285
0.00002
0.755
DataSet_02_26
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FMR1
147026424_147026571_147026463_147026571_147024650_147024846
0.00578
-0.187
DataSet_02_26
View details
LDHD
75147863_75148132_75147863_75148063_75148423_75148583
0.00043
-0.43
DataSet_02_26
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Showing 1 to 10 of 15 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ADD1
2910241_2911158_2910241_2910331_2911065_2911158
0.00001
-0.8
DataSet_02_26
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BAP1
52436794_52437314_52436794_52436956_52437153_52437314
0.00000
-0.667
DataSet_02_26
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BRD2
32944338_32945347_32944338_32944713_32945036_32945347
0.00152
0.418
DataSet_02_26
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CARMIL3
24534166_24534959_24534166_24534482_24534830_24534959
0.00000
1.0
DataSet_02_26
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CDCA3
6958486_6959022_6958486_6958577_6958728_6959022
0.00111
-0.281
DataSet_02_26
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DDIT3
57911051_57911536_57911051_57911221_57911488_57911536
0.00138
0.535
DataSet_02_26
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DDX51
132625375_132625965_132625375_132625565_132625819_132625965
0.00038
-0.226
DataSet_02_26
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ECSIT
11618516_11618863_11618516_11618544_11618805_11618863
0.00120
0.5
DataSet_02_26
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FAAH
46871259_46871750_46871259_46871466_46871709_46871750
0.00059
-0.433
DataSet_02_26
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LINC00937
8542865_8543565_8542865_8543107_8543497_8543565
0.00000
-0.9
DataSet_02_26
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
40147856
T
C
0.00205
HPCAL4
-
TRUE
chr1
161932324
A
G
0.00056
ATF6
+
FALSE
chr1
226333556
C
A
0.00977
ACBD3
-
FALSE
(CAAAA)n
SINE,Alu
chr1
16891340
T
A
0.00022
NBPF1
-
FALSE
chr1
144931101
G
A
0.00358
NBPF20,PDE4DIP
+,-
FALSE
chr1
145689537
A
G
0.00593
NBPF20,NBPF10
+
TRUE
AluSg
SINE,Alu
chr1
67874731
T
C
0.00125
SERBP1
-
TRUE
AluSx3
SINE,Alu
chr1
36068369
T
C
0.00511
PSMB2
-
TRUE
AluSc
SINE,Alu
chr1
204524546
A
G
0.00054
MDM4
+
TRUE
AluY
SINE,Alu
chr1
1337841
C
A
0.00186
MRPL20
-
FALSE
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression