Dataset Overview
RBP
DDX6
Knock-Method
CRISPR
RBP Family
DEAD
Biosample Name
hESCs
Tissue Type
Embryo
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
GEO
Profile ID
GSE112383
Platform
GPL11154
Pubmed ID
31588046
DDX6 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of DDX6
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A2ML1
1.38
2.9
1.38949
2.25935E-25
3.95186E-24
A4GALT
1.99
4.76
1.25441
4.82426E-18
5.32318E-17
AAAS
35.55
28.67
-0.42839
3.35000E-08
1.48376E-07
AACS
16.25
25.38
0.64742
1.17713E-19
1.44062E-18
AACSP1
0.68
4.55
2.71939
1.01112E-56
5.62952E-55
AADAT
4.37
7.82
0.72069
2.17663E-08
9.90130E-08
AAGAB
32.71
31.46
-0.16617
0.02921
0.04996
AAK1
3.55
4.62
0.57007
1.17208E-05
3.78533E-05
AAMDC
12.23
19.7
0.63233
1.55548E-05
4.92990E-05
AARS
66.95
57.66
-0.22498
0.00079
0.00187
Showing 1 to 10 of 9,709 entries
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Function Analysis of Target Genes of DDX6
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AC010522.1
58331861_58331917_58331086_58331313_58367474_58367601
0.00661
0.333
DataSet_02_28
View details
AC010522.1
58367474_58367601_58331098_58331313_58369943_58370181
0.00120
-0.5
DataSet_02_28
View details
AC074386.1
144008683_144008797_143948417_143948703_144040279_144040391
0.00939
-0.477
DataSet_02_28
View details
ADAMTS19
128796794_128797450_128795957_128796175_128844769_128844935
0.00000
0.433
DataSet_02_28
View details
ADNP
49521302_49521386_49520425_49520538_49545187_49545353
0.00350
-0.5
DataSet_02_28
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ADNP
49545187_49545362_49520425_49520538_49547362_49547527
0.00015
-0.495
DataSet_02_28
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ADPGK
73067212_73067438_73064123_73064186_73075586_73076072
0.00083
-0.615
DataSet_02_28
View details
AFMID
76201683_76201834_76201520_76201599_76202026_76202131
0.00056
-0.666
DataSet_02_28
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ANGEL1
77270717_77270758_77270128_77270255_77272758_77272858
0.00026
-0.198
DataSet_02_28
View details
APTX
32987541_32987844_32985968_32986028_32989756_32989893
0.00008
-0.667
DataSet_02_28
View details
Showing 1 to 10 of 95 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AFMID
76200908_76200981_76201520_76201599_76198783_76198832
0.00385
-0.416
DataSet_02_28
View details
ATP8A1
42592827_42592901_42596305_42596379_42590276_42590346
0.00172
-0.275
DataSet_02_28
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CADM1
115069125_115069158_115080293_115080377_115049363_115049495
0.00407
-0.184
DataSet_02_28
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EIF4G3
21324093_21324126_21327691_21327805_21307540_21307720
0.00013
0.592
DataSet_02_28
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EPB41
29424318_29424447_29435847_29435949_29391493_29391670
0.00356
-0.278
DataSet_02_28
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ITGB5
124527868_124528003_124536467_124536557_124515234_124515664
0.00016
0.7
DataSet_02_28
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LDLR
11213339_11213462_11215895_11216276_11210898_11211021
0.00000
-0.584
DataSet_02_28
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MLLT10
21846549_21846753_21860903_21860955_21827761_21827841
0.00181
-0.404
DataSet_02_28
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PTPA
131885330_131885417_131891263_131891389_131882791_131882889
0.00589
-0.25
DataSet_02_28
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SUN1
889156_889240_889559_889670_882977_883157
0.00331
-0.615
DataSet_02_28
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AP000347.1
24028976_24029182_24029024_24029182_24025930_24026054
0.00114
-0.537
DataSet_02_28
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CENPW
126661319_126661590_126661319_126661545_126667350_126667464
0.00216
-0.108
DataSet_02_28
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CTIF
46284289_46284782_46284289_46284776_46287760_46288060
0.00114
0.492
DataSet_02_28
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ING4
6761436_6761936_6761827_6761936_6760489_6760551
0.00226
0.5
DataSet_02_28
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MYL6
56552467_56553514_56552467_56552495_56553758_56553932
0.00000
-0.9
DataSet_02_28
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NDUFS5
39491989_39492074_39491989_39492070_39494394_39494612
0.00355
0.278
DataSet_02_28
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NDUFS8
67798209_67798428_67798209_67798344_67799618_67799676
0.00025
0.678
DataSet_02_28
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NUDT12
102895743_102895955_102895797_102895955_102894579_102895169
0.00155
-0.301
DataSet_02_28
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PCNT
47851442_47852129_47851442_47851892_47855816_47856061
0.00011
-0.634
DataSet_02_28
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PIGA
15349337_15350114_15349995_15350114_15344035_15344168
0.00159
0.313
DataSet_02_28
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Showing 1 to 10 of 15 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ATG4D
10657514_10657929_10657864_10657929_10655632_10655806
0.00120
0.5
DataSet_02_28
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C19orf60
18700222_18700493_18700288_18700493_18699804_18699887
0.00360
0.399
DataSet_02_28
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CAPRIN2
30872012_30873849_30872012_30872159_30876192_30876248
0.00000
0.451
DataSet_02_28
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FAM76B
95511985_95512121_95511985_95512118_95512770_95512851
0.00968
-0.253
DataSet_02_28
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FLOT1
30708966_30709481_30708966_30709110_30709568_30709644
0.00066
0.578
DataSet_02_28
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GPX4
1106179_1106265_1106240_1106265_1105656_1105808
0.00094
0.45
DataSet_02_28
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NASP
46070588_46070688_46070607_46070688_46067926_46068037
0.00091
-0.788
DataSet_02_28
View details
NPHP4
5965691_5965843_5965691_5965840_5967174_5967282
0.00147
-0.476
DataSet_02_28
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PIGQ
630182_630972_630857_630972_629068_629180
0.00253
0.54
DataSet_02_28
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RECQL
21654103_21654306_21654103_21654149_21654396_21654603
0.00431
-0.227
DataSet_02_28
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Showing 1 to 10 of 13 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABCF3
183907042_183907231_183907042_183907065_183907175_183907231
0.00000
0.695
DataSet_02_28
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ACTG1
79478213_79478829_79478213_79478652_79478788_79478829
0.00004
-0.666
DataSet_02_28
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ADD1
2910241_2911158_2910241_2910331_2911065_2911158
0.00630
-0.548
DataSet_02_28
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ARMC10
102724128_102724509_102724128_102724277_102724476_102724509
0.00079
-0.584
DataSet_02_28
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ATXN2L
28846598_28847079_28846598_28846720_28846866_28847079
0.00465
-0.643
DataSet_02_28
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DDIT3
57911051_57911536_57911051_57911221_57911488_57911536
0.00017
0.553
DataSet_02_28
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DENND6B
50752242_50752701_50752242_50752307_50752635_50752701
0.00004
-0.666
DataSet_02_28
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FTSJ3
61898198_61898475_61898198_61898298_61898389_61898475
0.00021
0.145
DataSet_02_28
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LIMD2
61776158_61776429_61776158_61776178_61776387_61776429
0.00120
-0.5
DataSet_02_28
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LMNTD2
555304_555930_555304_555503_555733_555930
0.00740
0.334
DataSet_02_28
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
36770600
G
T
0.00792
THRAP3
+
FALSE
(T)n
SINE,Alu
chr1
40219280
T
C
0.00169
PPIE
+
FALSE
chr1
179843781
T
C
0.00888
TOR1AIP2
-
TRUE
AluJb
SINE,Alu
chr1
6282400
T
C
0.00118
ICMT
-
TRUE
AluSz
SINE,Alu
chr1
145511988
A
G
0.00900
NBPF20,NBPF10,RBM8A,GNRHR2
+,-
FALSE
AluY
SINE,Alu
chr1
46828460
C
T
0.00101
NSUN4
+
FALSE
chr1
93301947
C
T
0.00039
FAM69A,RPL5
+,-
FALSE
chr1
1647814
T
C
8.49337E-05
CDK11B,CDK11A
-
FALSE
chr1
6282400
T
C
0.00132
ICMT
-
TRUE
AluSz
SINE,Alu
chr1
26143726
G
T
0.00556
SEPN1
+
FALSE
AluSx
SINE,Alu
Showing 1 to 10 of 357 entries
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression