Dataset Overview
RBP
ZNF598
Knock-Method
siRNA
RBP Family
Non-canonical_RBP
Biosample Name
U2OS
Tissue Type
Bone
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
GEO
Profile ID
GSE116126
Platform
GPL18573
Pubmed ID
30917308
ZNF598 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of ZNF598
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
5S_rRNA
2.51
1.36
-0.64824
0.04585
0.08760
A2M
4.2
7.19
1.00780
4.38088E-37
1.74155E-35
A2M-AS1
1.4
0.69
-1.03926
2.21463E-05
8.73868E-05
A4GALT
1.67
3.19
0.97786
6.83036E-08
3.78242E-07
AAAS
36.08
29.86
-0.33431
6.13492E-11
4.77611E-10
AACSP1
9.99
6.97
-0.46551
3.15065E-09
2.03905E-08
AAED1
6.58
9.87
0.44588
1.73543E-07
9.11608E-07
AAGAB
43.27
43.02
-0.11181
0.01283
0.02908
AAK1
22.08
19.94
-0.20790
1.47364E-06
6.92892E-06
AAMDC
11.06
17.18
0.64515
1.44884E-05
5.90936E-05
Showing 1 to 10 of 9,239 entries
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Function Analysis of Target Genes of ZNF598
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AC008770.1
12100983_12101196_12098581_12098638_12112588_12112637
0.00149
-0.298
DataSet_02_29
View details
AC090114.3
128218017_128218087_128214773_128214845_128218943_128218987
0.00004
-0.439
DataSet_02_29
View details
ADNP
49521302_49521386_49520425_49520538_49545187_49545353
0.00035
-0.152
DataSet_02_29
View details
AFMID
76198579_76198684_76186791_76187141_76198783_76198815
0.00154
0.667
DataSet_02_29
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AP2S1
47349249_47349399_47342721_47342835_47354020_47354023
0.00835
-0.45
DataSet_02_29
View details
AP3S2
90420537_90420656_90414706_90414778_90421496_90421532
0.00112
-0.525
DataSet_02_29
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ARMCX2
100914393_100914487_100914061_100914134_100914742_100914820
0.00058
0.567
DataSet_02_29
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ATG9A
220093155_220093204_220092643_220092775_220093731_220094047
0.00430
0.323
DataSet_02_29
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ATP6V1B1-AS1
71174663_71174801_71168956_71169563_71175356_71175740
0.00052
-0.473
DataSet_02_29
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AXIN1
341189_341297_339439_339607_343487_343718
0.00691
0.175
DataSet_02_29
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Showing 1 to 10 of 152 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ARIH2
48962150_48962272_48982568_48982614_48960180_48960244
0.00492
-0.723
DataSet_02_29
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EXOG
38540416_38540480_38541580_38541655_38539119_38539269
0.00001
0.583
DataSet_02_29
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FAM49B
130892621_130892704_130906732_130906810_130891634_130891717
0.00402
-0.25
DataSet_02_29
View details
GRB10
50778571_50778687_50799968_50800065_50771517_50771605
0.00634
-0.243
DataSet_02_29
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NASP
46056894_46056942_46067926_46068037_46049716_46049877
0.00369
-0.517
DataSet_02_29
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NT5C3B
39985041_39985204_39987052_39987142_39983677_39983878
0.00024
-0.625
DataSet_02_29
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NUMA1
71761707_71761879_71773634_71773732_71746947_71747021
0.00243
0.75
DataSet_02_29
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PIKFYVE
209138744_209138777_209141435_209141554_209138307_209138457
0.00395
-0.294
DataSet_02_29
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SEC31A
83782783_83782861_83783686_83783725_83778841_83778917
0.00169
-0.334
DataSet_02_29
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SENP7
101117704_101117899_101136436_101136634_101090851_101090970
0.00003
0.75
DataSet_02_29
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Showing 1 to 10 of 13 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AFTPH
64806619_64808407_64806619_64806680_64812555_64812679
0.00008
0.121
DataSet_02_29
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AP000347.1
24028976_24029182_24029024_24029182_24025930_24026054
0.00202
-0.383
DataSet_02_29
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ATXN2L
28847253_28847806_28847253_28847443_28848048_28848558
0.00020
-0.433
DataSet_02_29
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BAX
49458804_49459090_49458804_49458856_49459454_49459590
0.00766
-0.352
DataSet_02_29
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CFL2
35182459_35182767_35182713_35182767_35182265_35182342
0.00873
0.459
DataSet_02_29
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CHIC2
54915121_54915277_54915205_54915277_54880229_54880286
0.00436
-0.109
DataSet_02_29
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DHRS2
24113617_24113752_24113617_24113704_24114035_24114091
0.00474
0.098
DataSet_02_29
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DHRS2
24113617_24113763_24113617_24113752_24114035_24114091
0.00521
-0.144
DataSet_02_29
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ENGASE
77077979_77078959_77077979_77078145_77079101_77079205
0.00000
0.7
DataSet_02_29
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EXOSC2
133572968_133573638_133572968_133573014_133574715_133574781
0.00001
0.567
DataSet_02_29
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Showing 1 to 10 of 20 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACSL4
108926364_108926895_108926364_108926781_108976367_108976554
0.00172
-0.541
DataSet_02_29
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ARIH2
48982414_48982614_48982568_48982614_48960180_48960244
0.00284
-0.361
DataSet_02_29
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BRD4
15378964_15379092_15378964_15379051_15379715_15379853
0.00083
-0.247
DataSet_02_29
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CAPRIN2
30872012_30873849_30872012_30872159_30876192_30876248
0.00171
0.534
DataSet_02_29
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CD46
207958963_207959027_207959000_207959027_207958415_207958451
0.00289
0.5
DataSet_02_29
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CD58
117061852_117061924_117061852_117061889_117064527_117064605
0.00009
0.285
DataSet_02_29
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CMTM7
32493557_32493965_32493883_32493965_32490945_32491044
0.00675
-0.153
DataSet_02_29
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CTSA
44520911_44521123_44521036_44521123_44520554_44520666
0.00005
-0.416
DataSet_02_29
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EIF4A1
7477863_7477996_7477865_7477996_7477577_7477626
0.00233
-0.752
DataSet_02_29
View details
FTH1
61727189_61727399_61727189_61727376_61734783_61735103
0.00729
-0.296
DataSet_02_29
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Showing 1 to 10 of 24 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABCF3
183907042_183907231_183907042_183907065_183907175_183907231
0.00000
-0.788
DataSet_02_29
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B4GALNT3
661632_663149_661632_661694_662356_663149
0.00194
-0.5
DataSet_02_29
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CDK16
47086392_47086622_47086392_47086498_47086558_47086622
0.00403
-0.419
DataSet_02_29
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CPSF7
61183576_61183991_61183576_61183634_61183835_61183991
0.00134
0.282
DataSet_02_29
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CUTA
33384873_33385087_33384873_33384919_33385023_33385087
0.00572
0.334
DataSet_02_29
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DENND6B
50752242_50752701_50752242_50752307_50752635_50752701
0.00203
-0.166
DataSet_02_29
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DPH1
1939263_1939980_1939263_1939385_1939722_1939980
0.00005
0.75
DataSet_02_29
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DPP7
140008694_140009028_140008694_140008830_140008914_140009028
0.00070
-0.479
DataSet_02_29
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KDELC1
103443250_103443780_103443250_103443488_103443607_103443780
0.00468
0.278
DataSet_02_29
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KRTCAP2
155142266_155144965_155142266_155142333_155144826_155144965
0.00729
-0.225
DataSet_02_29
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
146250905
G
C
0.00444
NBPF20,NBPF10,NBPF25P
+
FALSE
chr1
206580231
A
G
0.00100
SRGAP2
+
FALSE
chr1
36068275
T
C
0.00098
PSMB2
-
TRUE
AluSc
SINE,Alu
chr1
32687473
T
G
0.00892
TMEM234,EIF3I
+,-
FALSE
chr1
114449662
T
C
0.00223
DCLRE1B
+
FALSE
chr1
86852621
A
G
0.00930
ODF2L
-
FALSE
chr1
86815303
T
C
0.00571
ODF2L
-
FALSE
chr1
38158705
G
A
0.00168
CDCA8
+
FALSE
chr1
16890671
T
C
0.00097
NBPF1
-
FALSE
chr1
36068237
T
C
0.00291
PSMB2
-
TRUE
AluSc
SINE,Alu
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression