Dataset Overview
RBPDDX6
Knock-MethodshRNA
RBP FamilyDEAD
Biosample NameNHNP
Tissue TypeBrain
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceGEO
Profile IDGSE124072
PlatformGPL11154
Pubmed ID31588046

DDX6 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of DDX6
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of DDX6


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr4160280309GT0.00770RAPGEF2+FALSE(T)nSINE,Alu
chr1453242354TC3.85910E-06GNPNAT1-TRUEAluJoSINE,Alu
chr128662186AG8.22643E-05MED18+TRUEAluSq2SINE,Alu
chr594050487TA0.00380MCTP1-FALSE
chr1194863483CT0.00501ENDOD1+FALSE
chr1919792288AG0.00379ZNF101+TRUEAluJbSINE,Alu
chr11344998AG0.00235.FALSEAluSgSINE,Alu
chr3195415462GA0.00140LINC00969,SDHAP2+FALSE
chr126755643AG0.00068LIN28A+FALSEAluScSINE,Alu
chr468483804AT0.00720UBA6-FALSE
chr129464358AG0.00056LOC642846+FALSE
chr273957124AG2.00679E-05TPRKB-FALSE
chr133149373AG0.00239SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr310005392TC8.76084E-06EMC3-FALSEAluSg7SINE,Alu
chr239212567TG0.00546SOS1-FALSE
chr287002706GA0.00178RMND5A+FALSE
chr119232017TG0.00723IFFO2-FALSE
chr7128167988TC0.00290.FALSEAluSgSINE,Alu
chr1089623858GC0.00086PTEN+FALSE(CGG)nSINE,Alu
chr314986137TC0.00132FGD5-AS1-TRUEFLAM_CSINE,Alu
chr210942687CT0.00082PDIA6-FALSE
chr110520725TC0.00795DFFA-TRUEAluSc8SINE,Alu
chr320195395CT3.65176E-06KAT2B+FALSE
chr4248713AG0.00367ZNF876P+FALSE
chr119542455TC0.00506LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr153291420AG0.00069ZYG11B+TRUEAluJrSINE,Alu
chr147840953AG0.00404CMPK1+FALSE
chr133149363AG0.00368SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chrX77083955TC0.00065MAGT1-TRUEAluSzSINE,Alu
chr7295960TA2.17882E-07FAM20C+FALSE
chr1748771486GA0.00081ANKRD40-FALSEAluSzSINE,Alu
chr3196670095CA1.97381E-07NCBP2-AS2+FALSE
chr1765335445TC0.00084PSMD12-TRUEAluSxSINE,Alu
chr299772827AG0.00108LIPT1+TRUEAluSx1SINE,Alu
chr16282324TC0.00142ICMT-TRUEAluSzSINE,Alu
chr1138156GT0.00048LOC729737-FALSE
chr5135388663AG1.64165E-07TGFBI+FALSE
chr275887834TC0.00024MRPL19+FALSEL1MB4SINE,Alu
chr128826118AG0.00023PHACTR4+TRUEAluJbSINE,Alu
chr2131906031CT0.00374PLEKHB2+FALSE
chr1144874815TC0.00701NBPF20,PDE4DIP+,-FALSE
chr2025428384AG0.00195GINS1+TRUEAluSzSINE,Alu
chr116842064AC0.00081.FALSEMER41ESINE,Alu
chr830536544TC5.33169E-07GSR-TRUEAluSpSINE,Alu
chr2204301753TA0.00012RAPH1-FALSE
chr116889866GA0.00995NBPF1-FALSE
chr5149763305AG0.00640TCOF1+FALSE
chr11573181CA0.00038CDK11B-FALSE
chr3181430334GA0.00305SOX2-OT,SOX2+FALSE
chr1176176230GA0.00091RFWD2-FALSE
chrX118672577TC0.00080CXorf56-TRUEAluSxSINE,Alu
chr136531781GA0.00288.FALSE
chr126449341AG0.00622PDIK1L+FALSE
chr28823951AT0.00251ID2+FALSE
chr1152884246GT0.00536IVL+FALSE
chr765618786AG3.58027E-08CRCP+TRUEAluSx3SINE,Alu
chr1327441AG1.08612E-09.FALSE
chr114106402AT0.00914PRDM2+FALSE
chr2191555980TA0.00913NAB1+FALSE
chr128661831AG9.37902E-09MED18+TRUEAluSgSINE,Alu
chr9127711532TC0.00018SCAI-TRUEAluSpSINE,Alu
chr133148210AG0.00342SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr174928356AG0.00048KIF1C+TRUEAluSzSINE,Alu
chr1181058313GA0.00651IER5+FALSE
chr127204865TC0.00132.FALSEAluSxSINE,Alu
chr123833607AT0.00831E2F2-FALSE
chr3196079389TC0.00509.FALSEAluSxSINE,Alu
chr775045694CT1.64957E-05NSUN5P1+FALSE
chr12124146100AG4.66106E-08GTF2H3+TRUEAluSx4SINE,Alu
chr1619715518TC0.00502.FALSEAluSgSINE,Alu
chr28823958GA0.00017ID2+FALSE
chr19815354TG0.00212CLSTN1-FALSE
chr11152310CT0.00133SDF4-FALSE
chr1942375586AG0.00016.FALSEAluSxSINE,Alu
chr145452227GC0.00084EIF2B3-FALSE
chr136642420TC0.00162MAP7D1+FALSE
chr2200813126TC0.00713TYW5-FALSE
chr193803622TC0.00096CCDC18-AS1-TRUEAluJrSINE,Alu
chr146829013AG0.00360NSUN4+FALSE
chr116889633TC0.00217NBPF1-TRUE
chr145976262AC0.00010MMACHC+FALSE
chr3196082911TC0.00250UBXN7-FALSE
chr2134728144AG2.75061E-05IFNAR1+TRUEAluScSINE,Alu
chr16282301TC0.00290ICMT-TRUEAluSzSINE,Alu
chr2025427801AG0.00300GINS1+TRUEAluSzSINE,Alu
chr110520117TC0.00188.FALSEAluSxSINE,Alu
chr1193054575CG0.00029TROVE2+FALSE(ATTTT)nSINE,Alu
chr765992665TC2.17687E-05.FALSEAluJrSINE,Alu
chr1117945049GA0.00030MAN1A2+FALSE
chr1201846627AT0.00571IPO9+FALSE(CA)nSINE,Alu
chr127202812TC0.00388.FALSEAluSq2SINE,Alu
chr1565442523GA0.00068CLPX-FALSEAluSg4SINE,Alu
chr457326156AG0.00170PAICS+TRUEAluJrSINE,Alu
chr128566461TC1.61071E-05.FALSEAluSx1SINE,Alu
chr177482325TA5.04428E-06.FALSE
chr1206635244TA0.00195SRGAP2+FALSE
chr642856176AG0.00202RPL7L1+TRUEAluSzSINE,Alu
chr349394834GA0.00000GPX1-FALSE
chrX77084042TC0.00703MAGT1-TRUEAluSzSINE,Alu
chr1118167515CT3.85037E-05FAM46C+FALSE
chr1584873635CT0.00059LOC440300,GOLGA2P7+,-FALSE
chr285548074TC0.00428TGOLN2-FALSE
chr347386059TC9.15846E-06KLHL18+FALSE
chr1154919080CT0.00376PBXIP1-FALSE
chr1117117182CT0.00270IGSF3-FALSE
chr388104158TA0.00971CGGBP1-FALSE
chr2036147563TC0.00313BLCAP-TRUE
chr125894464GA0.00527LDLRAP1+FALSEMIRbSINE,Alu
chr1167759281TC0.00923MPZL1+FALSE
chr1109746728AG0.00171KIAA1324+TRUEAluJbSINE,Alu
chr237327280AT0.00831.FALSEL1MB8SINE,Alu
chr237331201TC0.00291.FALSEAluSx1SINE,Alu
chr1156613517CA0.00011BCAN+FALSE
chr132631809CT1.50957E-07KPNA6+FALSE
chr2206981856TC0.00174.FALSEAluJbSINE,Alu
chr3167727417CT2.31470E-08GOLIM4-FALSE
chr136068184TC0.00150PSMB2-TRUEAluScSINE,Alu
chr1114940227TC0.00852TRIM33-FALSE(T)nSINE,Alu
chr165901227AT0.00914LEPR,LEPROT+FALSEAluYh3SINE,Alu
chr72650926GA0.00306IQCE+FALSE
chr1142690928CA0.00022.FALSE
chr2189877304AT0.00612COL3A1+FALSE
chr119586532AG0.00166MRTO4+TRUEAluSzSINE,Alu
chr1113672616AG0.00553.FALSEAluJbSINE,Alu
chr1155282600AG0.00019FDPS+TRUEAluSpSINE,Alu
chr1171501831AG0.00037PRRC2C+FALSE
chr119585207GA0.00672MRTO4+FALSE
chr2187544222AG0.00411ITGAV+FALSE
chr4187509420GA0.00121FAT1-FALSE
chr145987557GC0.00921PRDX1-FALSE
chr642855200AG2.13337E-05RPL7L1+TRUEAluSpSINE,Alu
chr167874731TC0.00613SERBP1-TRUEAluSx3SINE,Alu
chr4763539GC0.00816PCGF3+FALSE
chr537291636TC0.00518.FALSEAluSx3SINE,Alu
chr167896040GA1.31286E-05SERBP1-FALSE
chr116892918TC0.00158NBPF1-FALSE
chr186817074GT9.65311E-06ODF2L-FALSEL1PA7SINE,Alu
chr129848629AG0.00027CLEC2D+FALSE
chr19330479CT0.00027H6PD+FALSE
chr21168781CA0.00650SNTG2+FALSE
chr1150446028GT0.00624RPRD2+FALSE
chr1120839680AC0.00584FAM72B+FALSE
chr5132203384TA0.00651UQCRQ+FALSE
chr11252180TC0.00021CPSF3L-TRUEAluSxSINE,Alu
chr1942375584AG0.00021.FALSEAluSxSINE,Alu
chr5159829024GC0.00400SLU7-FALSE
chr7137561078GA0.00558CREB3L2-FALSE(GT)nSINE,Alu
chr1168212509AG0.00765.FALSE
chr117395521GA0.00788PADI2-FALSE
chr119586501AG0.00055MRTO4+TRUEAluSzSINE,Alu
chr738764332TC0.00209VPS41-TRUEAluSpSINE,Alu
chr1145689812AG0.00431NBPF20,NBPF10+TRUEAluJbSINE,Alu
chr1236714710CT0.00014LGALS8,HEATR1+,-FALSE
chr457326126AG0.00017PAICS+TRUEAluJrSINE,Alu
chr110520174TC0.00413.FALSEAluSxSINE,Alu
chr132661564CT0.00058TXLNA+FALSE(T)nSINE,Alu
chr1773886212TC0.00724TRIM65-TRUEFRAMSINE,Alu
chr2137789767AG0.00236.FALSEAluSxSINE,Alu
chr338566722TC0.00426EXOG+FALSEMIRbSINE,Alu
chr388199298TC0.00048C3orf38+FALSE
chr1151966348CT0.00511S100A10-FALSE
chr345636213CG0.00240.FALSE
chr1559428230GA0.00891MYO1E-FALSEMLT1BSINE,Alu
chr119543247TC0.00813LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr637138024GC0.00892PIM1+FALSE(GCA)nSINE,Alu
chr317201871TC0.00626TBC1D5-FALSE
chr2128064448GT0.00637MAP3K2-FALSE(GT)nSINE,Alu
chr2128602507TC4.02376E-05.FALSEAluSq2SINE,Alu
chr123240255GA0.00873EPHB2+FALSE
chr1114306374GA0.00124RSBN1-FALSE
chr744842429TG0.00384PPIA+FALSE
chr1936260451AG0.00854.FALSEAluYSINE,Alu
chr340577752AG0.00111ZNF621+TRUEAluSzSINE,Alu
chr2132275343GT0.00334LOC150776+FALSE
chr120945055CT0.00542CDA+FALSE
chr111347164AC0.00667UBIAD1+FALSE
chr116889639TC0.00524NBPF1-TRUE
chr1242012149CT0.00334EXO1+FALSE
chr5290324TA0.00729PDCD6+FALSE
chr41205667AC0.00611CTBP1-AS,CTBP1+,-FALSE(A)nSINE,Alu
chr145975498AG9.09033E-05MMACHC+TRUEAluSx4SINE,Alu
chr128661633AG0.00053MED18+TRUEAluSgSINE,Alu
chr1144053661TG0.00232.FALSE
chr3126755134CT0.00920PLXNA1+FALSE
chr146093407CA0.00700GPBP1L1-FALSEA-richSINE,Alu
chr2109301897TC0.00306LIMS1+FALSE
chr357611237AG9.49839E-05DENND6A,PDE12+,-FALSE
chr729961939GT1.47033E-05SCRN1-FALSE
chr119586360TC0.00023MRTO4+FALSE
chr192862337AG0.00595.FALSEAluSpSINE,Alu
chr1762109CT0.00026LINC00115-FALSE
chr16582161TC0.00697NOL9-TRUEAluSq4SINE,Alu
chrX16781687AG0.00298.FALSEAluSx1SINE,Alu
chr398516118TA0.00541DCBLD2-FALSE
chr1145509570AG0.00306NBPF20,NBPF10,RBM8A+TRUEAluJrSINE,Alu
chr577655392TC0.00080SCAMP1-AS1-TRUEAluSx4SINE,Alu
chr86263057AC0.00419LOC100287015-FALSE
chr116893686GC0.00296NBPF1-FALSE
chr155224131TC0.00169PARS2-FALSE
chr195712458CA0.00135RWDD3+FALSE
chr140537923GA0.00609CAP1+FALSE(A)nSINE,Alu
chr1933882222GA0.00236PEPD-FALSE
chr126608017TA3.67009E-06.FALSE
chr348787118TC0.00248PRKAR2A-TRUEAluSx3SINE,Alu
chr1113212974AT0.00424CAPZA1+FALSE
chr198005999TC0.00027TIMM44-FALSE
chr456291751AC0.00291TMEM165+FALSE
chr126611197CT0.00814UBXN11-FALSE
chr755266417TC0.00201EGFR+FALSE
chr1148241546GA0.00416NBPF8-FALSEU1SINE,Alu
chr1320211AG6.69717E-05.FALSEAluJoSINE,Alu
chr119586294AG0.00048MRTO4+FALSE
chr1541591417AG2.88542E-07OIP5-AS1+TRUEAluSxSINE,Alu
chr1120612163CA0.00812NOTCH2-FALSE
chr299812465AG2.16984E-05MRPL30+TRUEAluSxSINE,Alu
chr1145511988AG0.00900NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr2102508658TA0.00275MAP4K4+FALSE
chr1298942886AG1.80851E-07TMPO+TRUEAluScSINE,Alu
chr1774560725TC0.00476SNHG16+FALSETHE1BSINE,Alu
chr145976112AG1.14998E-06MMACHC+TRUEAluJrSINE,Alu
chr1610625101TC0.00804EMP2-TRUEAluSx3SINE,Alu
chr1615794023AG4.91052E-06NDE1+TRUEAluSz6SINE,Alu
chr6114182251CT0.00021MARCKS+FALSE
chr1230415244TC0.00360GALNT2+FALSE
chr342636141GA0.00224SEC22C,SS18L2+,-FALSE
chr1201355943CT0.00355LAD1-FALSE
chr286252136TC0.00015POLR1A-TRUEAluSq2SINE,Alu
chr1213244381GA0.00345RPS6KC1+FALSE
chr237331025TC0.00029.FALSEAluSx1SINE,Alu
chr1269158881AG0.00219SLC35E3+TRUEAluSpSINE,Alu
chr1488933002CG0.00459PTPN21-FALSE
chr2127826533AG0.00104BIN1-FALSE
chr1169101257AT0.00144ATP1B1+FALSE
chr738764358TC0.00675VPS41-TRUEAluSpSINE,Alu
chr136068276TC2.73596E-05PSMB2-TRUEAluScSINE,Alu
chr12133298937AG0.00240PGAM5+TRUEAluSgSINE,Alu
chr328390351AG0.00200AZI2-FALSE
chr12125511312AG0.00638THRIL-FALSEAluSx1SINE,Alu
chr286249930TC6.06022E-05LOC90784-TRUEAluJrSINE,Alu
chr211053740CT0.00402KCNF1+FALSE
chr167874859TC0.00209SERBP1-TRUEAluSxSINE,Alu
chr261764922GC0.00679XPO1-FALSE
chr5118174855TC1.06010E-07DTWD2-TRUEAluYSINE,Alu
chr315113847TC0.00026RBSN-TRUEAluSz6SINE,Alu
chr1778226862AC0.00590SLC26A11+FALSE
chr1113672616AG0.00940.FALSEAluJbSINE,Alu
chr16283305TC0.00554ICMT-TRUEAluSx3SINE,Alu
chr110519912TC5.10285E-06.FALSEAluJrSINE,Alu
chr2198572083TA0.00272MARS2+FALSE
chr2114220055TC9.23000E-05CBWD2+FALSE
chr585916592GA0.00018.FALSE
chr12133298417AG6.66134E-16PGAM5+TRUEAluSpSINE,Alu
chr237327670TC5.08697E-08.FALSE
chr110517527TC8.32015E-05.FALSEAluSx1SINE,Alu
chr1151095753AG0.00256GABPB2+TRUEAluSzSINE,Alu
chr1145513017AG3.59549E-05NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr145975345AG0.00227MMACHC+TRUEAluSg7SINE,Alu
chr2110373919GA0.00240SOWAHC+FALSE
chr1145291494AG0.00738NBPF20+FALSEMIRbSINE,Alu
chr1942753034AG0.00883ERF-FALSE
chr237431639TC0.00160CEBPZOS,CEBPZ+,-FALSEAluScSINE,Alu
chr146075664AG0.00267NASP+TRUEAluSx4SINE,Alu
chr5149823789GT0.00793.FALSE
chr29630248GT0.00764ADAM17-FALSE
chr19162933CT0.00088.FALSE
chr1205739266CT0.00125RAB29-FALSE
chr3195962244GT0.00083.FALSE
chr1757281069AG0.00278PRR11+TRUEAluSzSINE,Alu
chr6150047430TC0.00107NUP43-TRUEAluScSINE,Alu
chr5137891109CG0.00031HSPA9-FALSE
chr286252049TC0.00271POLR1A-FALSEAluSq2SINE,Alu
chr72394991CT9.93448E-08EIF3B+FALSE
chr1179045672GA0.00920FAM20B+FALSE
chr629910583CT4.95604E-05.FALSE
chr187573963TC0.00978HS2ST1+FALSE
chr114590GA0.00050WASH7P-FALSE
chr2231683849AG0.00786CAB39+FALSE
chr1757281060AG0.00026PRR11+TRUEAluSzSINE,Alu
chr81730500AG3.50527E-05CLN8+TRUEAluSx1SINE,Alu
chr179109331GT0.00379IFI44L+FALSELTR26SINE,Alu
chr2191067764AT0.00165C2orf88+FALSE
chr255516937GT0.00250CCDC88A-FALSE(GA)nSINE,Alu
chr116893763TC0.00159NBPF1-FALSE
chr135646125CT0.00027SFPQ-FALSE
chr3193854148TA0.00106HES1+FALSE
chr1541597437TA0.00217.FALSEAluSz6SINE,Alu
chr116952481AG0.00093CROCCP2-FALSE
chr110519951TC0.00378.FALSEAluJrSINE,Alu
chr261764895CA0.00862XPO1-FALSE(AC)nSINE,Alu
chr136068276TC0.00067PSMB2-TRUEAluScSINE,Alu
chr143917637GA0.00164SZT2,HYI+,-FALSE
chr1155695998AG0.00078DAP3+TRUEAluSpSINE,Alu
chr1144596317CT0.00020NBPF20+FALSEAluJbSINE,Alu
chr174928416AG0.00941KIF1C+TRUEAluSzSINE,Alu
chr138326700TC5.61462E-05INPP5B-TRUEAluJrSINE,Alu
chr126606589CG0.00420SH3BGRL3+FALSE
chr1072648336CT0.00461PCBD1-FALSE(GGCCG)nSINE,Alu
chr8144940794GC0.00038EPPK1-FALSE
chr110520378TC8.57705E-06.FALSEAluSx1SINE,Alu
chr1202848587GA2.63176E-05RABIF-FALSE
chr117313654CT0.00886ATP13A2-FALSE
chr189225976TC0.00586PKN2+FALSE
chr1152552285CA0.00400LCE3D-FALSE
chr1689623607AG0.00915SPG7+FALSE
chr110517314TC0.00368.FALSEAluJrSINE,Alu
chr5118174668TC1.32199E-05DTWD2-TRUEAluYSINE,Alu
chr1743471481GA0.00412.FALSE
chr232535836AG0.00163.FALSEAluJbSINE,Alu
chr1453242425TC0.00473GNPNAT1-TRUEAluJoSINE,Alu
chr5145493224AT0.00251LARS-FALSE
chr553841241TA0.00372SNX18+FALSE
chr146159809TA0.00761TMEM69+FALSE
chr1153617980AG0.00272CHTOP+FALSE
chr799636947AG0.00851ZKSCAN1+FALSEAluSx1SINE,Alu
chr7135291501TC0.00627NUP205+FALSE
chr2109401283CT0.00039RANBP2+FALSE
chr145280109AG0.00591.FALSEAluYk3SINE,Alu
chrX23721458TA0.00413.FALSEAluSc8SINE,Alu
chr116958047CT2.98219E-05.FALSE
chr632800221CT0.00900.FALSE(GCATCA)nSINE,Alu
chr146828700AG0.00805NSUN4+FALSE
chr413604182TC1.45661E-06BOD1L1-FALSE
chr1225706943CT0.00229ENAH-FALSE
chr312598618CT0.00812MKRN2+FALSE
chrX3523061CG0.00023PRKX-FALSE(AC)nSINE,Alu
chr6150046603TC0.00763NUP43-TRUEAluSq2SINE,Alu
chr186816600AG0.00830ODF2L-FALSEL1PA7SINE,Alu
chr16283260TC0.00125ICMT-TRUEAluSx3SINE,Alu
chr417804879TC0.00863DCAF16-TRUEAluSxSINE,Alu
chr1179042544AG0.00722FAM20B+TRUEAluSx1SINE,Alu
chr1352952680GA7.53266E-06THSD1-FALSE
chr11345002AG0.00141.FALSEAluSgSINE,Alu
chr1148010952CT0.00393NBPF8-FALSE

Differential Expression Gene Analysis