Dataset Overview
RBPEIF4A2
Knock-MethodCRISPR
RBP FamilyDEAD
Biosample NameHEK293T
Tissue TypeKidney
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceGEO
Profile IDGSE126298
PlatformGPL20301
Pubmed ID-

EIF4A2 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of EIF4A2
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of EIF4A2


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr111722350CA0.00355FBXO44+FALSEOldhAT1SINE,Alu
chr1648388258AG8.02686E-05MIR5095+TRUEAluSzSINE,Alu
chr264863970CT9.52027E-09SERTAD2-FALSE
chr247398328GA0.00434CALM2-FALSE
chr9136209396CT0.00126MED22-FALSE
chr345721934AG0.00011LIMD1,LIMD1-AS1+,-FALSEAluJbSINE,Alu
chr116842064AC0.00079.FALSEMER41ESINE,Alu
chr136067677TC0.00522PSMB2-TRUEAluSzSINE,Alu
chr237327670TC5.08697E-08.FALSE
chr16283260TC0.00125ICMT-TRUEAluSx3SINE,Alu
chr1120612163CA0.00812NOTCH2-FALSE
chr5140594470GA0.00041PCDHB13+FALSE
chr2201253956AG1.78964E-05SPATS2L+FALSE
chr2158170017TC0.00662GALNT5+FALSE
chr310028294GA1.35555E-07EMC3-FALSE
chr1162752670GA0.00594.FALSE
chr1900720AT0.00065KLHL17+FALSE(TTTA)nSINE,Alu
chr3182614493TC0.00195ATP11B+FALSE
chr1726672363GA0.00599TNFAIP1+FALSE
chr1160967856TC0.00027F11R-TRUEAluSpSINE,Alu
chr116060892CT0.00946PLEKHM2+FALSE
chr193803522TC0.00163CCDC18-AS1-TRUEAluJrSINE,Alu
chr9111781030CT0.00413TMEM245-FALSEAluJbSINE,Alu
chr1680636808CT0.00881CDYL2-FALSE
chr11597403CT0.00912CDK11B,SLC35E2B-FALSE
chr1145688664AT0.00298NBPF20,NBPF10,RNF115+FALSE
chr164810507GA0.00021ZNF500-FALSE
chr199672979TC0.00028.FALSEAluSx3SINE,Alu
chr119542310TC0.00873LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr112628188TC3.43513E-08DHRS3-FALSE
chr286249961TC0.00292LOC90784-TRUEAluJrSINE,Alu
chr3195962244GT0.00083.FALSE
chr145975279TC0.00019MMACHC+FALSEAluSg7SINE,Alu
chr170696606CA0.00362SRSF11+FALSE
chr119543247TC5.35430E-06LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr1179042687AG0.00782FAM20B+TRUEAluSx1SINE,Alu
chrX2825075TC0.00410ARSD-TRUEAluSx1SINE,Alu
chr2198339559GT0.00712COQ10B+FALSE
chr1911256697TC0.00039SPC24-TRUEAluJr4SINE,Alu
chr1183218868TG0.00091NMNAT2-FALSE
chr265496075CT0.00972ACTR2+FALSE
chr1120539711GT0.00627NOTCH2-FALSE
chr779848334GT0.00158GNAI1+FALSE
chr1674656352TC0.00187RFWD3-TRUEAluJbSINE,Alu
chr471682341TC0.00584GRSF1-TRUEAluSz6SINE,Alu
chr237331525TC0.00479.FALSEAluJbSINE,Alu
chr631378510GA0.00104.FALSE
chr115989141CG0.00364.FALSE
chr186046472GT0.00409CYR61+FALSE
chr347386062TA4.63678E-05KLHL18+FALSE
chr110043053AG0.00318NMNAT1+TRUEAluScSINE,Alu
chr1143399383TA0.00053.FALSEL1MC4SINE,Alu
chr596110979AT0.00020ERAP1-FALSE
chr123833607AT0.00890E2F2-FALSE
chr285837797TC0.00050USP39,C2orf68+,-FALSEAluSxSINE,Alu
chr581571875AT0.00072RPS23-FALSE
chr344790759TC0.00744KIAA1143-TRUEAluYSINE,Alu
chr5290174CT0.00083PDCD6+FALSE
chr1145512078AG0.00099NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr11245164CT0.00318PUSL1+FALSE
chr237327670TC0.00021.FALSE
chr75107572AC0.00563RBAK-RBAKDN,RBAK+FALSEL1ME3ASINE,Alu
chr1615219677AG0.00136PDXDC1,PKD1P6-NPIPP1+,-FALSE
chr127204436TC1.54117E-06.FALSEAluSg7SINE,Alu
chr1269237056AG0.00372MDM2+TRUE
chr1958371837AG0.00329ZNF587+TRUEAluSzSINE,Alu
chr128836872AG0.00019SNHG3,RCC1+TRUEAluScSINE,Alu
chr2238484068TC0.00047RAB17-FALSE
chr9131071425AT0.00068TRUB2-FALSE
chr3122283294GC0.00066DTX3L,PARP9+,-FALSE
chr124295888TA0.00240.FALSE
chr110519888TC0.00878.FALSEAluJrSINE,Alu
chr19162348TC0.00023.FALSEAluSxSINE,Alu
chr628873868TC0.00041.FALSEAluJoSINE,Alu
chr110521172TC0.00295DFFA-TRUEAluYSINE,Alu
chr56668842CT4.46208E-05SRD5A1+FALSE
chr42940135TC5.42423E-07NOP14-AS1,NOP14+,-FALSEAluSpSINE,Alu
chr2237035915CG0.00348AGAP1+FALSE
chr19644587AG0.00022.FALSEAluSxSINE,Alu
chr116011005GC0.00616PLEKHM2+FALSE(GCG)nSINE,Alu
chr489625427GC0.00025HERC3+FALSE
chr1161753841GA0.00039ATF6+FALSE
chr153365235GC0.00029ECHDC2-FALSE
chr237331065TC0.00585.FALSEAluSx1SINE,Alu
chr5118174855TC1.06010E-07DTWD2-TRUEAluYSINE,Alu
chr1154554951AG0.00554ADAR-FALSE
chr2172412829TA0.00477CYBRD1+FALSE
chr115993603GA0.00103.FALSEAluSx4SINE,Alu
chr272403402CA0.00108EXOC6B-FALSEGA-richSINE,Alu
chr1153587308CT0.00077S100A14-FALSE
chr220401855GA0.00107SDC1-FALSE
chr1153720690GA0.00550INTS3+FALSE
chr1015120275TC0.00387ACBD7-TRUEL1PA7SINE,Alu
chr297884961GA0.00668ANKRD36+FALSE
chr12123347005TA0.00268HIP1R+FALSE
chr555235866TA0.00073IL6ST-FALSE
chr136067811TC0.00467PSMB2-TRUEAluSzSINE,Alu
chr19162932AT0.00635.FALSE
chr165692498TC0.00356AK4+FALSE(T)nSINE,Alu
chr484525974TC0.00255GPAT3+FALSE(TTGTT)nSINE,Alu
chr116703160AT0.00111MRPL17-FALSE
chr5125961648AG4.28370E-08PHAX+FALSEAluSz6SINE,Alu
chr1157963370CG0.00445KIRREL+FALSE
chr417804879TC0.00863DCAF16-TRUEAluSxSINE,Alu
chr261277443AG0.00362PEX13+TRUEAluSxSINE,Alu
chr1138266CT7.30419E-05LOC729737-FALSE
chr146075777AG0.00268NASP+TRUEAluSx4SINE,Alu
chr116890176AC0.00753NBPF1-FALSE
chr136386884CT0.00024AGO1+FALSE
chr277745788TC0.00000LRRTM4-FALSE
chr138174665GA0.00475CDCA8+FALSE
chr136789546AG0.00562EVA1B-FALSEMIRbSINE,Alu
chr116927391TC0.00110NBPF1-FALSE
chr1912742509AG0.00717.FALSEAluSxSINE,Alu
chr3107773064TC0.00421CD47-TRUEFLAM_ASINE,Alu
chr145976723TC0.00239MMACHC,PRDX1+,-FALSE
chr1559952905AG0.00150BNIP2-FALSE
chr116892256TC0.00468NBPF1-FALSE
chr11593060TC0.00538CDK11B,SLC35E2B-FALSE
chr1206516261CT0.00020SRGAP2+FALSE
chr132661594CT0.00528TXLNA+FALSE(T)nSINE,Alu
chr4101946459CT0.00245PPP3CA-FALSE(T)nSINE,Alu
chr116907328GT0.00099NBPF1-FALSE
chr381698130TC2.93981E-08GBE1-FALSE
chr4169847647AT0.00328PALLD+FALSE
chr4152020782CT0.00989RPS3A+FALSE
chr534906661TC9.12853E-06RAD1-TRUEAluJoSINE,Alu
chr1742876738TC0.00481GJC1-TRUEAluSz6SINE,Alu
chr1120164545TG0.00058ZNF697-FALSE
chr1114939633GA0.00188TRIM33-FALSE
chr1179084080TG0.00926ABL2-FALSE
chr116890428TA0.00233NBPF1-FALSE
chr136299630AG0.00828AGO4+FALSE
chr1150597527TC0.00058ENSA-FALSE
chr227315252GA0.00377KHK+FALSE
chr16161107AT0.00218KCNAB2+FALSE
chr552386902AG0.00249ITGA2+FALSE
chr1054069186CT0.00089PRKG1-AS1-FALSE
chr191990445AG5.21972E-05CDC7+FALSELFSINE_VertSINE,Alu
chr1889183CT3.20836E-06NOC2L-FALSE
chr1160967833TC6.62581E-12F11R-TRUEAluSpSINE,Alu
chr579923293TC0.00039DHFR-TRUEAluJrSINE,Alu
chr192862804AG0.00043.FALSEAluJrSINE,Alu
chr1674698535TC0.00607RFWD3-TRUEAluSx3SINE,Alu
chr9132266644AG0.00081LINC00963+TRUEAluSxSINE,Alu
chr5130537998AG0.00380LYRM7+TRUEAluSpSINE,Alu
chr1256532056GC0.00743ESYT1+FALSE
chr140214148AG0.00426PPIE+TRUEAluSq2SINE,Alu
chr1619715588TC0.00063.FALSEAluSgSINE,Alu
chr146827871GA0.00860NSUN4+FALSE
chr540832551AT5.78892E-08RPL37-FALSE
chr1256632550GA0.00027ANKRD52-FALSE
chr398518158AT1.44910E-06DCBLD2-FALSE
chr167874689TC0.00053SERBP1-TRUEAluSx3SINE,Alu
chr11593857TC0.00424CDK11B,SLC35E2B-FALSE
chr2134729969AG0.00077IFNAR1+TRUEAluSg7SINE,Alu
chr1132125961CT0.00118RCN1+FALSE
chr123636016TG0.00796HNRNPR-FALSE
chr1144852203TG0.00029NBPF20,PDE4DIP+,-FALSE
chr195363041CT0.00105CNN3-FALSE
chr399517479TC8.06312E-05MIR548G-FALSE(TG)nSINE,Alu
chr16283260TC0.00054ICMT-TRUEAluSx3SINE,Alu
chr145244411CA0.00656RPS8+FALSE
chr1748771486GA0.00081ANKRD40-FALSEAluSzSINE,Alu
chr110367058GA0.00328KIF1B+FALSE
chr1160967857TC0.00032F11R-TRUEAluSpSINE,Alu
chr120977221AT0.00116PINK1,PINK1-AS+,-FALSE
chr2202031433AG0.00611CFLAR+FALSESVA_ASINE,Alu
chr1172580637TC1.47330E-06SUCO+FALSE
chr6114182982CA0.00308MARCKS+FALSE
chr19644562AG0.00337.FALSEAluSxSINE,Alu
chr719736460AG6.53378E-05TWISTNB-FALSEMER33SINE,Alu
chr452753346AG0.00782DCUN1D4+TRUEAluScSINE,Alu
chr126449340GA0.00711PDIK1L+FALSE
chr1919459215CT0.00068MAU2+FALSE
chr76695426GT0.00893ZNF316+FALSE
chr4103809324AC0.00658CISD2,SLC9B1+,-FALSE
chr123636274GT0.00032HNRNPR-FALSE
chr117394048TA0.00055PADI2-FALSE
chr1117078729AG0.00983CD58-FALSE
chr127175047AG0.00634C1S+FALSE
chr110517527TC0.00304.FALSEAluSx1SINE,Alu
chr7131241085GA0.00600PODXL-FALSE(GCA)nSINE,Alu
chr76202695AC0.00013CYTH3-FALSE
chr1155853251AG0.00207SYT11+TRUEAluJbSINE,Alu
chr6111588769AG2.24603E-05MFSD4B+TRUEAluYm1SINE,Alu
chr2233744021GA0.00460NGEF-FALSE
chr115818090TC0.00089CASP9-TRUEAluJbSINE,Alu
chr1146400122CG0.00039NBPF20,NBPF10,NBPF25P,NBPF12+FALSE
chr9111779229TC0.00269TMEM245-FALSE
chr4177252327AG2.51883E-09SPCS3+TRUE
chr1590819423AG3.09408E-05.FALSEAluSxSINE,Alu
chr19162423TC0.00074.FALSEAluSxSINE,Alu
chr549692280TC9.73531E-05EMB-FALSEL2cSINE,Alu
chr348787052TC0.00226PRKAR2A-TRUEAluSx3SINE,Alu
chr153291435AG0.00044ZYG11B+TRUEAluJrSINE,Alu
chr174928356AG0.00048KIF1C+TRUEAluSzSINE,Alu
chr116889575TC0.00467NBPF1-TRUE
chr103208557AG0.00128PITRM1-FALSE
chr344790781TC0.00060KIAA1143-TRUEAluYSINE,Alu
chr11252443TC8.33820E-06CPSF3L-TRUEAluJrSINE,Alu
chr124861704GA0.00345RCAN3+FALSE
chr1145116325TC0.00101NBPF20,SEC22B+FALSE(TTTTGTTT)nSINE,Alu
chr314986137TC1.37684E-08FGD5-AS1-TRUEFLAM_CSINE,Alu
chr1200558363TC1.35174E-05KIF14-FALSE
chr1244871041TA0.00590DESI2+FALSE
chr16283306TC0.00558ICMT-TRUEAluSx3SINE,Alu
chr1205738302GA0.00247RAB29-FALSE
chr227170943AC0.00684DPYSL5+FALSE(CA)nSINE,Alu
chr1146629399GT0.00611PRKAB2-FALSE
chr314986104TC6.10128E-05FGD5-AS1-TRUEFLAM_CSINE,Alu
chr135657874GC0.00738SFPQ-FALSE
chr3148748380TC0.00240HLTF-FALSE
chr72290522CT0.00517NUDT1+FALSE
chr42940164TC2.22609E-06NOP14-AS1,NOP14+,-FALSEAluSpSINE,Alu
chr116841620TA0.00023.FALSE
chr314986104TC0.00621FGD5-AS1-TRUEFLAM_CSINE,Alu
chr163790503TC0.00289FOXD3+FALSE
chr1206516261CT0.00179SRGAP2+FALSE
chr224224000AG0.00464.FALSEAluSpSINE,Alu
chr1215035081TC0.00951MGP-FALSE
chr237330611TC0.00835.FALSEAluSq2SINE,Alu
chr119585903GA0.00522MRTO4+FALSEAluJrSINE,Alu
chr6149915565AG0.00198RPS18P9+FALSE
chr568850966GT0.00134OCLN+FALSEAluSx4SINE,Alu
chr10120920588TC0.00304SFXN4-FALSE
chr1214524633TA0.00017PTPN14-FALSEAluSINE,Alu
chr137948912CT0.00084ZC3H12A+FALSE
chr363996262CT0.00681PSMD6-AS2,PSMD6+,-FALSE
chr1765334767TC3.33546E-08PSMD12-TRUEAluSqSINE,Alu
chr224223265AG0.00417UBXN2A+TRUEAluScSINE,Alu
chr246612340GT3.13955E-05EPAS1+FALSE
chr110240685CT0.00422UBE4B+FALSE
chr312613866TC0.00043MKRN2+FALSE
chr1212796592AC0.00801CREBL2+FALSE
chr1220232066TC0.00673RNU5F-1,BPNT1+,-FALSEAluSzSINE,Alu
chr138001685TC0.00050SNIP1-TRUEAluSxSINE,Alu
chr1148343689AG0.00517NBPF8,NBPF14,NBPF9-FALSE
chr410442610TC0.00174ZNF518B-FALSE
chr124296874GA0.00627.FALSEAluSgSINE,Alu
chr1610623706TC0.00064EMP2-TRUEAluSpSINE,Alu
chr2143638992TA0.00089KYNU+FALSE
chr116889624TC0.00614NBPF1-TRUE
chr112073252AG0.00990MFN2+FALSE
chr110520117TC0.00188.FALSEAluSxSINE,Alu
chr564964627TC2.01273E-05SGTB-TRUEAluSx1SINE,Alu
chr122400707CG0.00232CDC42+FALSEAluSc8SINE,Alu
chr124296856TG0.00564.FALSEAluSgSINE,Alu
chr1779004271TC0.00200BAIAP2-AS1-FALSEAluSq2SINE,Alu
chr146125880TC0.00686GPBP1L1-FALSE
chr1958356540AG0.00019ZNF587B+TRUEAluSxSINE,Alu
chr1179042300CA0.00491FAM20B+FALSE
chr119602076TC7.58058E-05WEE1+FALSEAluSgSINE,Alu
chr1269237020AG0.00378MDM2+TRUE
chr29629306GT0.00255ADAM17-FALSE
chr116893691CA0.00566NBPF1-FALSE
chr3196046746TC0.00513TM4SF19-TCTEX1D2,TM4SF19-AS1+,-FALSEAluSc5SINE,Alu
chr123631625AG0.00536HNRNPR-FALSEUCON44SINE,Alu
chr1169101257AT0.00144ATP1B1+FALSE
chr310192784AG1.73909E-05VHL+TRUEAluSx1SINE,Alu
chr178414329GA0.00303FUBP1-FALSEA-richSINE,Alu
chr131902343TC1.48709E-05SERINC2+FALSE
chr1109855152AC0.00227SORT1-FALSEA-richSINE,Alu
chr2232319615AT8.19218E-06NCL-FALSE
chr2179969921AT0.00203SESTD1-FALSE
chr128825337AG0.00904PHACTR4+TRUEAluSgSINE,Alu
chr23627302AT0.00021RPS7+FALSE
chr63022725TC0.00081HTATSF1P2-TRUEAluSzSINE,Alu
chr119542410TC0.00270LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr11595586TC0.00206CDK11B,SLC35E2B-TRUEAluJrSINE,Alu
chr12125512534AG0.00024.FALSE
chr1144619903TA0.00712NBPF20,NBPF9+FALSE
chr128835937AG2.00244E-07SNHG3,RCC1+TRUEAluSx4SINE,Alu
chr1109856391GC0.00569SORT1-FALSE
chr1201846627AT0.00571IPO9+FALSE(CA)nSINE,Alu
chr237328034TC6.77479E-07.FALSE
chr1461112736TG0.00418SIX1-FALSE(T)nSINE,Alu
chr457326159AG0.00019PAICS+TRUEAluJrSINE,Alu
chr342591956GA0.00503SEC22C-FALSE
chr227293352AT0.00314AGBL5,OST4+,-FALSE
chr697592897AC0.00144MMS22L-FALSE
chr136068237TC0.00075PSMB2-TRUEAluScSINE,Alu
chr3184550501AG0.00508VPS8+FALSE
chr189447720GA0.00030KYAT3,RBMXL1-FALSE
chr919063167CT0.00539HAUS6-FALSE
chr1671681515AG0.00308PHLPP2-FALSE
chr187573349CG0.00914HS2ST1+FALSE
chr155207985GA0.00156MROH7-TTC4,TTC4+FALSE
chr211426734TC4.76290E-06ROCK2-FALSE
chr5149363273AG0.00114SLC26A2+TRUEAluJrSINE,Alu
chr1462213927CA0.00771HIF1A,HIF1A-AS2+,-FALSE
chr6150047430TC0.00107NUP43-TRUEAluScSINE,Alu
chr310255002CG0.00043IRAK2+FALSE
chr1610623558TC0.00103EMP2-TRUEAluSpSINE,Alu
chr1144821986CT0.00218NBPF20,NBPF9+FALSE
chrX77084042TC0.00703MAGT1-TRUEAluSzSINE,Alu
chrX77083828TC1.52468E-05MAGT1-TRUEAluSzSINE,Alu
chr351738256AG0.00312TEX264+FALSE
chr194995491CT0.00036F3-FALSEAluSxSINE,Alu
chr154493197TC0.00148TMEM59-TRUEAluSz6SINE,Alu
chr140229368AG0.00209BMP8B,PPIE+,-FALSE
chrX71492446AT0.00281.FALSE
chr1205687344CT0.00633NUCKS1-FALSE(T)nSINE,Alu
chr2057603730AT0.00101.FALSE
chr154355105AG0.00325YIPF1-FALSEMIRbSINE,Alu
chr153288924AG0.00099ZYG11B+TRUEAluJoSINE,Alu
chr237327702TC0.00119.FALSE
chr63022544TC0.00440HTATSF1P2-TRUEAluJrSINE,Alu
chr1149783886CT0.00526HIST2H2BF-FALSE
chr190152146CT1.61967E-05LRRC8C+FALSE
chr644222156AT0.00856SLC35B2-FALSE
chr1197128726GA2.50329E-05ZBTB41-FALSE
chr2101622881CA1.48865E-05RPL31+FALSE
chr19163383TC0.00383.FALSEAluSpSINE,Alu
chr125169634AG0.00531CLIC4+FALSE
chr28996323GA0.00159MBOAT2-FALSE
chr1120612194CG0.00091NOTCH2-FALSE(CCG)nSINE,Alu
chr349396588TC0.00239RHOA-FALSE
chr1109746728AG0.00171KIAA1324+TRUEAluJbSINE,Alu
chr399516879AT7.79377E-13MIR548G-FALSE
chr165297860AT0.00847RAVER2+FALSE
chr1688767769GC0.00420RNF166-FALSE
chr652860422GC0.00024.FALSE7SKSINE,Alu
chr115896984AG0.00297DNAJC16+FALSEFLAM_CSINE,Alu
chr1089623865AC0.00348PTEN+FALSE
chr116112795AG4.56234E-06FBLIM1+FALSE
chr168940887TG0.00293DEPDC1-FALSEMIRSINE,Alu

Differential Expression Gene Analysis