Dataset Overview
RBPATXN2
Knock-MethodshRNA
RBP FamilySM-ATX
Biosample NameMEG-01
Tissue TypeBlood
Biosample TypeCell line
# of Control3
# of Treat3
SpeciesHuman
Data SourceGEO
Profile IDGSE131308
PlatformGPL16791
Pubmed ID-

ATXN2 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of ATXN2
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of ATXN2


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr1194863483CT0.00501ENDOD1+FALSE
chr128564252AG0.00986ATPIF1+FALSE
chr119542354TC0.00684LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr310302056AG0.00018TATDN2+FALSE
chr11345006AG1.26297E-06.FALSEAluSgSINE,Alu
chr6114181223AG0.00365MARCKS+FALSE
chr1689623607AG0.00915SPG7+FALSE
chr1684778690CT0.00799USP10+FALSE
chr193297605CG0.00319RPL5+FALSE
chr1101443701AG0.00749SLC30A7+FALSE
chr120977221AT0.00116PINK1,PINK1-AS+,-FALSE
chr28823952TG1.04377E-05ID2+FALSE
chr344791398TC0.00081KIAA1143-TRUEAluJrSINE,Alu
chr1015120278TC0.00018ACBD7-TRUEL1PA7SINE,Alu
chr220401855GA0.00107SDC1-FALSE
chr1149818441TC0.00773.FALSEMLT1DSINE,Alu
chr330733403AT0.00110TGFBR2+FALSE(TA)nSINE,Alu
chr5115165731TC5.24208E-07ATG12-TRUEAluSq2SINE,Alu
chr224223251AG0.00489UBXN2A+TRUEAluScSINE,Alu
chr186117122TC0.00462ZNHIT6-FALSEAluSgSINE,Alu
chr1131452750AG0.00326DNAJC24+TRUEAluSx1SINE,Alu
chr417626174TA0.00534MED28+FALSE
chr399517479TC8.06312E-05MIR548G-FALSE(TG)nSINE,Alu
chr145976220AG0.00031MMACHC+TRUE
chr1687443734CT0.00074ZCCHC14-FALSE
chr153289688AG0.00731ZYG11B+TRUEAluSzSINE,Alu
chr174665493GA0.00128FPGT-TNNI3K,FPGT+FALSE
chr1341635234TC0.00395.FALSE
chr116913612GA0.00145NBPF1-FALSE
chr1942375585AG0.00022.FALSEAluSxSINE,Alu
chr9115447533TC0.00326INIP-TRUEAluJbSINE,Alu
chr145242978AG0.00604RPS8+TRUEAluSzSINE,Alu
chr2174090635TA0.00138ZAK,MLK7-AS1+,-FALSE
chr16283264TC0.00521ICMT-TRUEAluSx3SINE,Alu
chr3124950418TA0.00039ZNF148-FALSE
chr174672474GA0.00441FPGT-TNNI3K,FPGT+FALSEX12_DNASINE,Alu
chr190401562CA0.00057LRRC8D+FALSE
chr246612340GT0.00094EPAS1+FALSE
chr1145509570AG0.00037NBPF20,NBPF10,RBM8A+TRUEAluJrSINE,Alu
chr139951484CA0.00592MACF1+FALSE
chr141326886CG0.00085CITED4-FALSE
chr116933631GA0.00927NBPF1-FALSEGA-richSINE,Alu
chr2238484068TC0.00047RAB17-FALSE
chr210179657AC0.00035.FALSEL1ME4bSINE,Alu
chr3100083427TA0.00456TOMM70-FALSEFAMSINE,Alu
chr13545189TG0.00027TPRG1L+FALSE
chr1453243411TC0.00028GNPNAT1-TRUEAluSx3SINE,Alu
chr167874859TC0.00071SERBP1-TRUEAluSxSINE,Alu
chr1226333558AC0.00722ACBD3-FALSE(CAAAA)nSINE,Alu
chr629857589AG0.00280.FALSE
chr5149013587GA0.00102ARHGEF37+FALSEL2dSINE,Alu
chr136068237TC0.00075PSMB2-TRUEAluScSINE,Alu
chr136068237TC0.00812PSMB2-TRUEAluScSINE,Alu
chr2043707759AG0.00090STK4+TRUEAluJbSINE,Alu
chr133148210AG0.00342SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr2128952699AG0.00497UGGT1+TRUEAluSpSINE,Alu
chr138423205AG0.00923SF3A3-FALSEAluJoSINE,Alu
chr11255401GT0.00216CPSF3L-FALSE(GCAGG)nSINE,Alu
chr11344749AG0.00307.FALSEAluSx1SINE,Alu
chr1149818508TC7.96693E-05.FALSEMLT1DSINE,Alu
chr553841240AG0.00416SNX18+FALSE
chr1100654765TC0.00254DBT-TRUEAluSzSINE,Alu
chr11656557TC0.00061SLC35E2-TRUEAluSzSINE,Alu
chr1145688664AT0.00013NBPF20,NBPF10,RNF115+FALSE
chr291805938AG0.00000.FALSEMLT1H1SINE,Alu
chr211321779AT0.00033ROCK2-FALSEAluSx1SINE,Alu
chr7100031496TA0.00119MEPCE+FALSE
chr2206983491TC0.00505.FALSEAluSxSINE,Alu
chr4169911112CA0.00142CBR4-FALSE
chr968413593CA0.00342.FALSE
chr631324643GC5.95617E-06.FALSE
chr128661656AG0.00106MED18+TRUEAluSgSINE,Alu
chr830536450TC8.74573E-07GSR-TRUEAluSpSINE,Alu
chr1201846675CT0.00145IPO9+FALSE
chr233812352AG0.00223FAM98A-FALSE
chr3196230564GC0.00842RNF168-FALSE
chr1213069783AG0.00600FLVCR1+FALSE
chr1150704483TC0.00028CTSS-TRUEAluJoSINE,Alu
chr743665371AT0.00430STK17A,COA1+,-FALSE(AG)nSINE,Alu
chr2206981874TC0.00060.FALSEAluJbSINE,Alu
chr1145323668GC0.00241NBPF20,NBPF10+FALSE
chr3158320703CA0.00841MLF1+FALSE
chr29770610AG0.00466YWHAQ-FALSE
chr11255412CA0.00751CPSF3L-FALSE(GCAGG)nSINE,Alu
chr1214529740TC0.00356PTPN14-TRUE
chr1194903795GT0.00328SESN3-FALSE
chr140214333AG0.00112PPIE+TRUEAluSq2SINE,Alu
chr2105881071CA0.00851TGFBRAP1-FALSE
chr237334146TC0.00039EIF2AK2-TRUEAluSzSINE,Alu
chr170718280AC0.00946.FALSE
chr11594940TC0.00115CDK11B,SLC35E2B-TRUEAluSgSINE,Alu
chr1145369007TG0.00703NBPF20,NBPF10+FALSE
chr1681064629AG6.04166E-07CENPN+TRUEAluSgSINE,Alu
chr1179042905AG0.00034FAM20B+TRUE
chr357612271TC0.00831DENND6A,PDE12+,-FALSEAluSpSINE,Alu
chr8145159705GA0.00383MAF1+FALSE
chr21637201CT5.10703E-15PXDN-FALSE
chr13654747CA0.00691TP73-AS1-FALSE
chr1142660333GA8.80387E-05.FALSE
chr1225684742TC0.00518ENAH-FALSE
chr133086876TC0.00672ZBTB8OS-TRUEAluYSINE,Alu
chr1919793729AG0.00124ZNF101+TRUEAluSc8SINE,Alu
chr9132575836AC0.00546TOR1A-FALSE
chr1117531813TC0.00751PTGFRN+FALSE
chr1204524457AG6.02506E-06MDM4+TRUEAluYSINE,Alu
chr549692633TG0.00808EMB-FALSE
chr136535403AG0.00320.FALSEAluSx1SINE,Alu
chr1204526713AG0.00078MDM4+TRUEAluSxSINE,Alu
chr1590627429TC0.00013IDH2-FALSE
chr1118502767GA0.00624WDR3,SPAG17+,-FALSE(GT)nSINE,Alu
chr2218572729AG0.00228PEX26+TRUEAluYf1SINE,Alu
chr574669972CT0.00113COL4A3BP-FALSE
chr124710405AG0.00246STPG1-FALSE
chr139988084GA0.00060BMP8A,PPIEL+,-FALSE
chr5115166350TC0.00148ATG12-TRUEAluJrSINE,Alu
chr110517313TC0.00196.FALSEAluJrSINE,Alu
chr1549283066TG0.00065SECISBP2L-FALSE
chr193616202TC0.00055TMED5-FALSE
chr11654038GA0.00290CDK11B,CDK11A-FALSE
chr110517567TC0.00262.FALSEAluSx1SINE,Alu
chr16704652CT1.57063E-06DNAJC11-FALSE
chr1202993614GT0.00990TMEM183A+FALSE(T)nSINE,Alu
chr127202812TC0.00356.FALSEAluSq2SINE,Alu
chr2133974088AG0.00057C21orf59-FALSE
chr2102508659AT0.00261MAP4K4+FALSE
chr159142713TC0.00246MYSM1-FALSE
chr2140567667AG0.00658BRWD1-FALSE
chr980886829CA6.48097E-06.FALSE(TTTCTTTT)nSINE,Alu
chr4169299528TC0.00745DDX60L-FALSE
chr7157129834CG1.26796E-05DNAJB6+FALSE
chr1225974581AG0.00732SRP9+TRUEAluJrSINE,Alu
chr127434251GA0.00504SLC9A1-FALSE
chr1953914807AG4.44644E-06ZNF765+TRUEAluSpSINE,Alu
chr1169799880GT0.00118C1orf112+FALSE
chr2112252629AC0.00107MIR4435-2HG-FALSE
chr310192642AG0.00217VHL+TRUEAluSx1SINE,Alu
chr128662182AG0.00402MED18+TRUEAluSq2SINE,Alu
chr1164820482TA0.00045PBX1+FALSE
chr1298943162AG5.01524E-05TMPO+TRUEAluSzSINE,Alu
chr1226333558AC0.00052ACBD3-FALSE(CAAAA)nSINE,Alu
chr1145116142AT0.00570NBPF20,SEC22B+FALSE
chr126158908GC0.00181MTFR1L,AUNIP+,-FALSE
chr1145512925AG0.00238NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr133148736AG0.00525SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr3160213318TG0.00215KPNA4-FALSE
chr340577761AG0.00701ZNF621+TRUEAluSzSINE,Alu
chr1949121788TC0.00017RPL18-FALSE
chr2110373938TG0.00413SOWAHC+FALSE(GAAT)nSINE,Alu
chr2217366590AG0.00013.FALSEAluSzSINE,Alu
chr116932809CT0.00074NBPF1-FALSEL1MC2SINE,Alu
chr11650797AG3.70820E-05CDK11B,CDK11A-FALSE
chr1619513719TA0.00730GDE1-FALSEAluJrSINE,Alu
chr1379188534TA0.00698RNF219-AS1,RNF219+,-FALSE
chr2179973026TC0.00210SESTD1-FALSE
chr147905555AC0.00661FOXD2+FALSE
chr1116771525TC0.00014C11orf58+FALSE
chr4144475125TG0.00133SMARCA5+FALSE
chr15937327CT0.00703NPHP4-FALSE
chr631506635TG6.78064E-05.FALSE
chr116958064AG0.00446.FALSE
chr1921367088AG0.00018ZNF431+TRUEAluScSINE,Alu
chr119543352TC0.00086LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr1203277253AG0.00624BTG2+FALSE
chr624720539GC0.00225.FALSE
chr315113733TC0.00228RBSN-TRUEAluSz6SINE,Alu
chr16583036TC0.00296NOL9-TRUEAluSx4SINE,Alu
chr1204526727AG0.00033MDM4+TRUEAluSxSINE,Alu
chr315113810TC0.00201RBSN-TRUEAluSz6SINE,Alu
chr299812447AG0.00501MRPL30+TRUEAluSxSINE,Alu
chr237330431TC0.00231.FALSEAluSq2SINE,Alu
chr128661657AG0.00011MED18+TRUEAluSgSINE,Alu
chr3183901281GA4.84515E-09AP2M1+FALSE
chr1101372409TC0.00203SLC30A7+FALSE
chr116384843GC0.00049FAM131C-FALSE
chr255459824CT0.00763RPS27A+FALSE
chr642857111AG0.00681RPL7L1+FALSEAluSpSINE,Alu
chr165898873GC0.00530LEPR,LEPROT+FALSE
chr187379494AT0.00364SEP15-FALSE
chr145976928GA0.00715PRDX1-FALSE
chr286249930TC6.06022E-05LOC90784-TRUEAluJrSINE,Alu
chr9131872857CG0.00151CRAT-FALSE
chr7116147752AG0.00031CAV2+FALSE(AAAAGAAA)nSINE,Alu
chr3179116220TC0.00233GNB4-TRUEAluSz6SINE,Alu
chr1229730452GA0.00236TAF5L-FALSE
chr1022824829TC0.00207PIP4K2A-FALSE
chr11337738CA4.14710E-05MRPL20-FALSE
chr541917695CT0.00546C5orf51+FALSE
chr185785548CT0.00350DDAH1-FALSE
chr4139091459TC9.74854E-05SLC7A11-AS1,SLC7A11+,-FALSE(TA)nSINE,Alu
chr1023408278CT0.00042MSRB2+FALSE
chr424801315GA9.79732E-09SOD3+FALSE
chr133149486AG5.00374E-05SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr1179042482AG1.77761E-07FAM20B+TRUEAluSx1SINE,Alu
chr729962664AC0.00077SCRN1-FALSE
chr299208209GA0.00609.FALSE
chr110520764TC0.00501DFFA-TRUEAluSc8SINE,Alu
chr413602231GA0.00646BOD1L1-FALSE
chr1950410816GT0.00050IL4I1,NUP62-FALSEAluSzSINE,Alu
chr119198576AG0.00542ALDH4A1-FALSE
chr146076533AG1.88265E-05NASP+TRUEAluSxSINE,Alu
chr2203742188TC0.00522.FALSEAluJbSINE,Alu
chr129464178GA0.00081LOC642846+FALSE
chr5180236449GC0.00011MGAT1-FALSE
chr136642328CT0.00971MAP7D1+FALSEGA-richSINE,Alu
chr1269237020AG0.00378MDM2+TRUE
chr3194999609GT0.00796ACAP2-FALSE
chr657034841GT0.00581ZNF451,LOC101927211+,-FALSE
chr187811103TG0.00028LMO4+FALSE
chr1953155625TC0.00074ZNF83-TRUEAluSgSINE,Alu
chr5134061340TA0.00493SEC24A+FALSE
chr2238285016AG0.00030.FALSEAluSzSINE,Alu
chr1220231370TC0.00826RNU5F-1,BPNT1+,-FALSEAluYSINE,Alu
chr1108113839TC1.78857E-05VAV3-FALSE
chr1154128827AT0.00724TPM3-FALSE
chr399517466GA0.00088MIR548G-FALSE(TG)nSINE,Alu
chr575469427GA0.00155SV2C+FALSE
chr126755510AG0.00013LIN28A+TRUEAluScSINE,Alu
chr11534826CT0.00382FNDC10-FALSE
chr457326126AG0.00790PAICS+TRUEAluJrSINE,Alu
chr13110407598AG0.00222IRS2-FALSE
chr1206581246TC0.00210SRGAP2+FALSE
chr647501448TC0.00017CD2AP+FALSE
chr624719404CA0.00024.FALSE
chr5179720333AG0.00308.FALSE
chr1475203036AG0.00837FCF1+TRUEAluSxSINE,Alu
chr110517276TC0.00779.FALSEAluJrSINE,Alu
chr11668168GT1.67311E-07SLC35E2-FALSEAluSzSINE,Alu
chr1143135063CA0.00397LOC102723769-FALSE
chr1748771486GA0.00081ANKRD40-FALSEAluSzSINE,Alu
chr1168523082TC0.00019CPT1A-TRUEAluYSINE,Alu
chr164935146CT0.00676PPL-FALSE
chr617557416GT0.00885CAP2+FALSE
chr1203839215TA0.00692SNRPE+FALSE
chr120238572AT0.00950OTUD3+FALSE
chr1145511998AG0.00715NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr1160966301TC7.77749E-07F11R-TRUEAluSgSINE,Alu
chr495588274GA0.00095PDLIM5+FALSE
chr756079033TC0.00300PSPH-TRUEAluYm1SINE,Alu
chr237331560TC0.00040.FALSEAluJbSINE,Alu
chr373025345AG0.00219.FALSEAluSzSINE,Alu
chr131732677GA0.00030SNRNP40-FALSEA-richSINE,Alu
chr1180854783TC0.00292XPR1+FALSE
chr138326704TC0.00328INPP5B-TRUEAluJrSINE,Alu
chr131344628TA0.00085SDC3-FALSE
chr194351064AT0.00620GCLM-FALSE
chr3191116133CT0.00032CCDC50+FALSE
chr7102016322AG0.00223LOC100289561,LOC100630923+FALSE
chrM2619AT0.00012RNR2+FALSELSU-rRNA_HsaSINE,Alu
chr1079552107GA0.00092DLG5-FALSE
chr228002599TA0.00566MRPL33+FALSE
chr1114940227TC0.00852TRIM33-FALSE(T)nSINE,Alu
chr5149363218AG0.00233SLC26A2+TRUEAluJrSINE,Alu
chr3197611048AG0.00573.FALSEAluSx1SINE,Alu
chr1117644949CG0.00440TTF2+FALSE
chr1203277244AG0.00115BTG2+FALSE
chr124086794GT0.00028TCEB3+FALSE(T)nSINE,Alu
chr145241587GA0.00248RPS8,SNORD55+FALSE
chr388104162TC0.00106CGGBP1-FALSE
chr9138798859CA0.00291CAMSAP1-FALSE
chr126774224AG0.00100DHDDS+TRUEAluSz6SINE,Alu
chr71199790GC0.00049ZFAND2A-FALSE
chr127202812TC0.00388.FALSEAluSq2SINE,Alu
chr1161932324AG0.00056ATF6+FALSE
chr514510067GT0.00130TRIO+FALSE
chr4247533AG0.00972ZNF876P+FALSE
chr110518591AT0.00811.FALSE
chr473923056TC0.00077COX18-TRUEAluSzSINE,Alu
chr28998555GA0.00584MBOAT2-FALSE
chr126608015TA3.80922E-07.FALSE
chr626368938CT0.00121BTN3A2+FALSE
chr1236716959CT0.00727HEATR1-FALSE
chr4248996AG0.00123ZNF876P+TRUEAluYk3SINE,Alu
chr1738512480CT0.00725RARA+FALSE
chr116910172GA0.00958NBPF1-FALSE
chr125893928TA0.00388LDLRAP1+FALSE
chr116932931CA0.00191NBPF1-FALSEL1MC2SINE,Alu
chr2176789423CA0.00441LNPK-FALSEMSTB1SINE,Alu
chr2219134117CT0.00357AAMP-FALSE
chr6105546950TC0.00443BVES-TRUEAluJbSINE,Alu
chr7129472356CT0.00279UBE2H-FALSE
chr1629454768AG0.00564SMG1P6,BOLA2-SMG1P6-FALSE
chr1492629726TA0.00787CPSF2+FALSE
chr552251222GT0.00808.FALSE(GATA)nSINE,Alu
chr136067858GA0.00293PSMB2-FALSEAluSzSINE,Alu
chr132742441GA2.50972E-10LCK+FALSE
chr119543457TC0.00101LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr1100654813TC0.00352DBT-TRUEAluSzSINE,Alu
chr1117648345AG0.00739.FALSE
chr264859679TC0.00824SERTAD2-FALSE
chr1151092875AG0.00154GABPB2+TRUEAluSpSINE,Alu
chr119282314GT0.00158IFFO2-FALSE
chr110043363AG0.00429NMNAT1+TRUEAluSx3SINE,Alu
chr2206985727CT0.00786.FALSEMIRcSINE,Alu
chr194335333GT0.00510DNTTIP2-FALSE
chr1242011534AG0.00248EXO1+FALSE
chr119411087CT0.00226UBR4-FALSE
chr1204524950AG4.72439E-07MDM4+TRUEAluSxSINE,Alu
chr128662212AG0.00098MED18+TRUEAluSq2SINE,Alu
chr1163394020AT0.00175ATL3-FALSE
chr117314702CT0.00140ATP13A2-FALSE
chr158946773CT0.00037OMA1-FALSE
chr1450361170CT0.00096ARF6+FALSE(T)nSINE,Alu

Differential Expression Gene Analysis