Dataset Overview
RBP
YTHDF2
Knock-Method
siRNA
RBP Family
YTH
Biosample Name
PSC
Tissue Type
Stem Cell
Biosample Type
Cell line
# of Control
2
# of Treat
4
Species
Human
Data Source
GEO
Profile ID
GSE133898
Platform
GPL18573
Pubmed ID
-
YTHDF2 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of YTHDF2
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A2ML1
2.17
1.44
-0.94968
0.04394
0.18821
AAED1
5.29
3.16
-1.12304
0.02554
0.15376
AAMDC
91.6
72.05
-0.76847
0.03551
0.17343
AAMP
6.72
23.68
1.25710
0.02231
0.14602
AAR2
2.92
10.96
1.39615
0.00739
0.10287
AARS
27.94
74.03
0.90488
0.02159
0.14418
ABCA2
0.56
3.27
2.35338
0.00014
0.02356
ABCA3
1.04
2.96
1.43448
0.01057
0.11443
ABCB4
0.18
0.42
1.57828
0.04274
0.18652
ABCB6
4.96
11.14
1.11589
0.02638
0.15609
Showing 1 to 10 of 3,657 entries
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Function Analysis of Target Genes of YTHDF2
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AC005083.1
20257410_20257481_20257208_20257245_20257878_20257986
0.00015
0.389
DataSet_02_43
View details
AC092490.1
8942595_8942859_8940869_8941382_8946900_8946932
0.00959
-0.028
DataSet_02_43
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AC106864.1
113568570_113568623_113567878_113568124_113569809_113569855
0.00001
-0.079
DataSet_02_43
View details
AFMID
76198579_76198684_76186791_76187141_76198783_76198815
0.00067
-0.167
DataSet_02_43
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AMZ2
66246934_66247108_66246423_66246621_66247190_66247206
0.00926
-0.221
DataSet_02_43
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APEX2
55028683_55028864_55027978_55028062_55029394_55029541
0.00217
0.132
DataSet_02_43
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APMAP
24949527_24949720_24943560_24944658_24950161_24950296
0.00020
0.155
DataSet_02_43
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APOBEC3C
39411599_39411756_39410087_39410384_39413770_39414050
0.00254
0.028
DataSet_02_43
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APOC1
45419446_45419727_45418128_45418206_45422429_45422601
0.00641
-0.043
DataSet_02_43
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ATP5J
27106643_27106686_27101941_27102112_27107163_27107215
0.00004
-0.12
DataSet_02_43
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Showing 1 to 10 of 126 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AL121594.3
35782086_35782265_35783566_35783661_35779945_35780101
0.00215
0.116
DataSet_02_43
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LYPLA1
54975887_54975935_54978307_54978373_54974813_54974884
0.00418
0.259
DataSet_02_43
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PSMA4
78834824_78834987_78836531_78836609_78834518_78834561
0.00204
-0.207
DataSet_02_43
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PTGES3
57059987_57060050_57064058_57064148_57058559_57058584
0.00237
0.492
DataSet_02_43
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RPS2
2012497_2012657_2012736_2012910_2012061_2012271
0.00322
-0.061
DataSet_02_43
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SEC11A
85223943_85224063_85230855_85231005_85213955_85214013
0.00240
-0.255
DataSet_02_43
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SEC31A
83782783_83782861_83783686_83783725_83778841_83778917
0.00012
0.345
DataSet_02_43
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ALDH18A1
97393247_97393406_97393253_97393406_97392715_97392806
0.00109
0.094
DataSet_02_43
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ANAPC15
71823695_71823826_71823779_71823826_71822457_71822542
0.00000
0.512
DataSet_02_43
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ATP5L
118277651_118277812_118277651_118277691_118279714_118279914
0.00965
0.263
DataSet_02_43
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BCL9
147084681_147084998_147084681_147084776_147086225_147086415
0.00194
0.194
DataSet_02_43
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CENPW
126661319_126661590_126661319_126661545_126667350_126667464
0.00000
0.041
DataSet_02_43
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DPY30
32264661_32264874_32264801_32264874_32264489_32264561
0.00007
-0.074
DataSet_02_43
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HMGN3
79911992_79912106_79912033_79912106_79910961_79911443
0.00025
0.09
DataSet_02_43
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HSD17B10
53458745_53458854_53458772_53458854_53458205_53458542
0.00023
0.03
DataSet_02_43
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MYL6
56553370_56553514_56553370_56553406_56553758_56553932
0.00262
0.196
DataSet_02_43
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NUDT12
102895743_102895955_102895797_102895955_102894579_102895169
0.00052
0.313
DataSet_02_43
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Showing 1 to 10 of 22 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AFMID
76193215_76193641_76193226_76193641_76187050_76187141
0.00280
0.099
DataSet_02_43
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ALAS1
52233225_52233456_52233236_52233456_52232687_52232864
0.00000
-0.418
DataSet_02_43
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ATP5G2
54063654_54063898_54063654_54063732_54066359_54066429
0.00009
-0.324
DataSet_02_43
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CA14
150236057_150236078_150236060_150236078_150235697_150235818
0.00358
0.228
DataSet_02_43
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CENPV
16251929_16252647_16251929_16251999_16253244_16253343
0.00003
0.116
DataSet_02_43
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CNIH4
224563496_224567154_224566770_224567154_224553580_224553693
0.00996
0.032
DataSet_02_43
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ECH1
39306496_39306995_39306496_39306647_39307092_39307163
0.00507
0.129
DataSet_02_43
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EDF1
139756570_139756948_139756570_139756797_139757357_139757451
0.00004
0.039
DataSet_02_43
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FLVCR1-AS1
213029945_213030514_213029945_213030260_213031107_213031430
0.00321
0.125
DataSet_02_43
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GMFB
54947591_54947677_54947591_54947674_54948126_54948176
0.00013
-0.234
DataSet_02_43
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Showing 1 to 10 of 17 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABCC5
183701540_183705705_183701540_183702682_183705557_183705705
0.00000
0.329
DataSet_02_43
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ATP5G1
46970770_46972696_46970770_46970818_46972517_46972696
0.00868
0.079
DataSet_02_43
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B9D1
19246482_19247170_19246482_19246774_19247102_19247170
0.00045
0.148
DataSet_02_43
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CENPV
16251929_16252647_16251929_16251999_16252453_16252647
0.00000
0.714
DataSet_02_43
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CUTA
33384326_33384553_33384326_33384437_33384525_33384553
0.00000
0.608
DataSet_02_43
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EXOSC8
37577070_37578698_37577070_37577144_37578613_37578698
0.00000
0.735
DataSet_02_43
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FAM133B
92206968_92207496_92206968_92206990_92207463_92207496
0.00075
0.593
DataSet_02_43
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KRTCAP2
155142266_155144965_155142266_155142333_155144826_155144965
0.00000
0.713
DataSet_02_43
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MYL6
56553370_56553932_56553370_56553406_56553758_56553932
0.00149
0.222
DataSet_02_43
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MYL6
56553370_56553932_56553370_56553406_56553808_56553932
0.00000
0.601
DataSet_02_43
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
46660295
T
C
0.00871
POMGNT1
-
FALSE
chr1
1255401
G
T
0.00216
CPSF3L
-
FALSE
(GCAGG)n
SINE,Alu
chr1
154323598
T
A
0.00198
ATP8B2
+
FALSE
(TA)n
SINE,Alu
chr1
11347142
C
G
0.00789
UBIAD1
+
FALSE
chr1
6282383
T
C
0.00371
ICMT
-
TRUE
AluSz
SINE,Alu
chr1
109795026
T
C
0.00355
CELSR2
+
FALSE
chr1
17733531
G
A
0.00223
RCC2
-
FALSE
chr1
74672474
G
A
0.00292
FPGT-TNNI3K,FPGT
+
FALSE
X12_DNA
SINE,Alu
chr1
12628188
T
C
3.43513E-08
DHRS3
-
FALSE
chr1
1650845
G
A
0.00094
CDK11B,CDK11A
-
FALSE
Showing 1 to 10 of 476 entries
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression