Dataset Overview
RBPCREBBP
Knock-MethodCRISPR
RBP FamilyNon-canonical_RBP
Biosample NameHAP1
Tissue TypeBlood
Biosample TypeCell line
# of Control1
# of Treat2
SpeciesHuman
Data SourceGEO
Profile IDGSE110142
PlatformGPL16791
Pubmed ID30664650

CREBBP - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of CREBBP
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of CREBBP


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr193827991AC0.00533DR1+FALSE
chr265539437CT0.00076SPRED2-FALSE
chr1118167515CT0.00018FAM46C+FALSE
chr1210029539GA0.00231DIEXF+FALSE
chr1615219677AG0.00136PDXDC1,PKD1P6-NPIPP1+,-FALSE
chr174672474GA0.00441FPGT-TNNI3K,FPGT+FALSEX12_DNASINE,Alu
chr1214527252GA0.00181PTPN14-FALSEMADE2SINE,Alu
chr111347142CG0.00789UBIAD1+FALSE
chr274645427AG0.00011C2orf81-FALSE
chr128826130AG0.00207PHACTR4+TRUEAluJbSINE,Alu
chr1919793876AG0.00080ZNF101+TRUEAluSc8SINE,Alu
chr1224380498AG6.58460E-05DEGS1+TRUEAluSxSINE,Alu
chr510265488AG0.00120CCT5+FALSE
chr12125514120AG0.00232.FALSE(TA)nSINE,Alu
chr175196073CT0.00159CRYZ-FALSE
chr224225509AG0.00132.FALSEAluSq2SINE,Alu
chr1109513497CT0.00186WDR47-FALSE
chr4129796173GT1.40481E-05JADE1+FALSE
chr1100316589AG0.00481AGL+FALSE
chr146827871GA0.00860NSUN4+FALSE
chr3149679162TA0.00235RNF13+FALSE
chr145976269CG0.00039MMACHC+FALSE
chr1180247483TC0.00167.FALSE
chr1757281058AG0.00061PRR11+TRUEAluSzSINE,Alu
chr225962254AT0.00375ASXL2-FALSE
chr116890500GA0.00030NBPF1-FALSE
chr574072638GA0.00431NSA2+FALSE
chr1013320123CA0.00830PHYH-FALSE
chr1149581866CG0.00774LINC00623,LINC00869,LOC103091866+FALSEL2bSINE,Alu
chrX123045342AG0.00381XIAP+FALSE(ATAA)nSINE,Alu
chr4153701130CT2.11271E-05ARFIP1+FALSE
chr1161732461GT2.02182E-05FTH1-FALSE
chr268402154AT0.00991PNO1+FALSE
chr128785597GC0.00595PHACTR4+FALSE
chr1148009510GA1.20657E-06NBPF8-FALSE
chr1949608GA0.00416ISG15+FALSE
chr110044366AG0.00958NMNAT1+TRUEAluSx1SINE,Alu
chr1116609833GA0.00773SLC22A15+FALSE
chr23605906CA0.00982RNASEH1-FALSE
chr2236677549CT0.00040MYH9-FALSE
chr16662500CG0.00235KLHL21-FALSE
chr856985611AT0.00028RPS20-FALSE
chr117314702CT0.00140ATP13A2-FALSE
chr1610623631TC1.36144E-05EMP2-TRUEAluSpSINE,Alu
chr133148096AG0.00404SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr671299074AG0.00824.FALSEAluSx1SINE,Alu
chr473922981TC0.00491COX18-TRUEAluSzSINE,Alu
chr837351214TC0.00109LINC01605-FALSE
chr125170760TA0.00975CLIC4+FALSE
chr116893721AC0.00043NBPF1-FALSE
chr116889413TC1.64789E-05NBPF1-TRUEL1MC4SINE,Alu
chr5178986987CT0.00651RUFY1+FALSE
chr116933658GA0.00699NBPF1-FALSEGA-richSINE,Alu
chr489179595TC0.00752PPM1K-TRUEAluScSINE,Alu
chr1100489835AG0.00230SLC35A3+TRUEAluSgSINE,Alu
chr310192798AG0.00722VHL+TRUEAluSx1SINE,Alu
chr618264355GA0.00872DEK-FALSE
chr237333924TC0.00298EIF2AK2-FALSEAluSzSINE,Alu
chr110517306TC0.00176.FALSEAluJrSINE,Alu
chr132373854AT0.00096PTP4A2-FALSE
chr237331750TC0.00067.FALSEAluJbSINE,Alu
chr187213190AC0.00054SH3GLB1+FALSE
chr3100083423TC0.00678TOMM70-FALSEFAMSINE,Alu
chr3155658362CT0.00807.FALSEMIR3SINE,Alu
chr1013320129AG0.00830PHYH-FALSE
chr2132049924AG0.00338LOC440910+FALSEAluSg4SINE,Alu
chr162882267GC0.00252ZG16B+FALSE
chr1610623553TC0.00024EMP2-TRUEAluSpSINE,Alu
chr1453242746TC0.00051GNPNAT1-TRUEAluJrSINE,Alu
chr1134370TC0.00327.FALSEAluSgSINE,Alu
chr310142949CT0.00721FANCD2,FANCD2OS+,-FALSE
chr2112252630AC0.00040MIR4435-2HG-FALSE
chr4119555188CA0.00205LOC729218+FALSE
chr121100856AC0.00010HP1BP3-FALSE(AC)nSINE,Alu
chr136068231TC0.00582PSMB2-TRUEAluScSINE,Alu
chr187170493TG0.00345SH3GLB1+FALSE
chr145187511TC7.71832E-06C1orf228+FALSEU5SINE,Alu
chr1541573612CA0.00355CHP1+FALSE
chr152306087CT0.00022NRDC-FALSE(TCA)nSINE,Alu
chr1674698535TC0.00607RFWD3-TRUEAluSx3SINE,Alu
chr3124688639CA0.00165HEG1-FALSE
chr346007825TC4.58354E-06FYCO1-FALSE
chr613788222TC0.00490MCUR1-TRUEAluSxSINE,Alu
chr132687473TG0.00892TMEM234,EIF3I+,-FALSE
chr224223159AG0.00717UBXN2A+TRUEAluScSINE,Alu
chr1109239334AT0.00035PRPF38B+FALSE
chr4103731698TC0.00029UBE2D3-TRUEAluYk2SINE,Alu
chr344791406TC0.00598KIAA1143-TRUEAluJrSINE,Alu
chr1298943187AG2.29648E-09TMPO+TRUEAluSzSINE,Alu
chr116890484GC0.00704NBPF1-FALSE
chr1201488771AG0.00062.FALSEAluSq2SINE,Alu
chr110518591AT0.00169.FALSE
chr5139876355GA0.00815ANKHD1,ANKHD1-EIF4EBP3+FALSEGA-richSINE,Alu
chr11662754TC0.00856SLC35E2-TRUEAluYSINE,Alu
chr765992665TC2.17687E-05.FALSEAluJrSINE,Alu
chr577655392TC0.00080SCAMP1-AS1-TRUEAluSx4SINE,Alu
chr132373437GA3.32434E-12PTP4A2-FALSE
chr1248539888CA0.00088PFKM+FALSE
chr744918732TC0.00039PURB-FALSEAluSgSINE,Alu
chr1204526554AG0.00194MDM4+TRUEAluSxSINE,Alu
chr126755455AG0.00342LIN28A+TRUEAluScSINE,Alu
chr1911257634TC0.00237SPC24-TRUEAluSpSINE,Alu
chr1145292925CT0.00817NBPF20+FALSE
chr1352952680GA7.53266E-06THSD1-FALSE
chr286249906TC0.00352LOC90784-TRUEAluJrSINE,Alu
chr2232196570AG0.00765ARMC9+FALSE
chr237076594TC0.00198STRN-FALSE
chr1155695968AG0.00439DAP3+TRUEAluSpSINE,Alu
chr129519595TC0.00208MECR-TRUEAluJbSINE,Alu
chr581571271TG0.00827RPS23-FALSE
chr1108113839TC1.78857E-05VAV3-FALSE
chr5170837890CA0.00030.FALSE
chr237334139TC0.00146EIF2AK2-TRUEAluSzSINE,Alu
chr123409538GA0.00292KDM1A+FALSE
chr10117823569GA0.00391GFRA1-FALSE(ATC)nSINE,Alu
chr1110950295CA0.00359LAMTOR5-FALSE
chr136642420TC0.00358MAP7D1+FALSE
chr110517276TC0.00604.FALSEAluJrSINE,Alu
chr116932144AC0.00559NBPF1-FALSE
chr310191943GA2.29886E-07VHL+FALSE
chr125893927AG0.00081LDLRAP1+FALSE
chr136921372AT0.00259MRPS15-FALSE
chr237331037TC0.00538.FALSEAluSx1SINE,Alu
chr579276281AG0.00026MTX3-FALSE
chr357743171CT1.04824E-07SLMAP+FALSE
chr1079800443AG0.00971RPS24+FALSE
chr166100450GA0.00528LEPR+FALSE
chr1179044110AG5.39593E-06FAM20B+TRUEAluSxSINE,Alu
chr119447819TC0.00337UBR4-FALSE
chr3188597556AG0.00309LPP+FALSE
chr1758024275AG0.00455RPS6KB1+FALSE
chr119953120GA0.00212MINOS1,MINOS1-NBL1+FALSE
chr1120695554GA0.00492.FALSE
chr121810575TC0.00827NBPF3+FALSE
chr312882839CG0.00118RPL32-FALSE
chr2206987731TC0.00731.FALSEAluJbSINE,Alu
chr642856330AG2.22045E-16RPL7L1+TRUE
chr1203766872GA1.42518E-06ZC3H11A,ZBED6+FALSE
chrX54587297AG0.00759GNL3L+TRUEAluSq2SINE,Alu
chr1765334846TC0.00456PSMD12-FALSEAluSqSINE,Alu
chr19163400TC0.00726.FALSEAluSpSINE,Alu
chr128835937AG2.00244E-07SNHG3,RCC1+TRUEAluSx4SINE,Alu
chr2191745655CG0.00163GLS+FALSE
chr310192720AG0.00110VHL+TRUEAluSx1SINE,Alu
chr6149912555GA0.00551.FALSE
chr190401416TC6.95799E-05LRRC8D+FALSE
chr126802401TG4.43852E-05HMGN2+FALSE
chr132638096CT0.00857KPNA6+FALSE
chr285776832CT0.00514GGCX-FALSE
chr119586501AG0.00288MRTO4+TRUEAluSzSINE,Alu
chr5180682607AC0.00161CTC-338M12.4+FALSE
chr1610625460TC0.00015EMP2-TRUEAluSxSINE,Alu
chr136068278TC0.00068PSMB2-TRUEAluScSINE,Alu
chr333877626GA2.14228E-08PDCD6IP+FALSE
chr1144833386AG0.00325NBPF20+FALSEL1MEcSINE,Alu
chr194352570GT0.00097GCLM-FALSEAluSx1SINE,Alu
chr644417142AG0.00020CDC5L+TRUEFLAM_CSINE,Alu
chr4119526740CG0.00435LOC729218+FALSE
chr195658358TC0.00633TMEM56-RWDD3,LOC101928118,TMEM56+,-FALSE
chr1148004422TA0.00017NBPF8-FALSE
chr5125961447AG0.00025PHAX+TRUEAluSz6SINE,Alu
chr1745761101GT0.00296.FALSE
chr125554719GA0.00403SYF2-FALSE
chrX2825075TC0.00410ARSD-TRUEAluSx1SINE,Alu
chr3108298260CT0.00042KIAA1524-FALSE
chr534906547TC0.00051RAD1-TRUEAluJoSINE,Alu
chr133148736AG0.00849SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr211323078CT0.00539ROCK2-FALSE
chr145279900TC0.00073.FALSE(TCTT)nSINE,Alu
chr1109856085GA0.00684SORT1-FALSE
chr145975345AG0.00614MMACHC+TRUEAluSg7SINE,Alu
chr1145290874CT0.00380NBPF20+FALSE
chr132799438AT0.00485MARCKSL1-FALSE
chr110520145TC0.00424.FALSEAluSxSINE,Alu
chr3196079305TC0.00161.FALSEAluSxSINE,Alu
chr137958451CG0.00882MEAF6-FALSEMER5BSINE,Alu
chr117299387TA0.00941CROCC+FALSE
chr3100083425GA0.00717TOMM70-FALSEFAMSINE,Alu
chr11595527TC0.00139CDK11B,SLC35E2B-TRUEAluJrSINE,Alu
chr19162394TC0.00072.FALSEAluSxSINE,Alu
chr2206987096TC0.00795.FALSEAluSxSINE,Alu
chr2219100202CT0.00027ARPC2+FALSEAluJrSINE,Alu
chr1160062340GA0.00967IGSF8-FALSE
chr237506939AG0.00119PRKD3-FALSE
chr1156005447CA0.00337UBQLN4-FALSE
chr1942375549AG4.56329E-05.FALSEAluSxSINE,Alu
chr1111991845CA0.00803WDR77,ATP5F1+,-FALSE
chr143391826GT0.00202SLC2A1-FALSE
chr194351064AT0.00212GCLM-FALSE
chr1244572645TG0.00103ADSS-FALSE
chr165898263AG0.00767LEPR,LEPROT+FALSEMIRcSINE,Alu
chr315114759GA1.99109E-05RBSN-FALSE
chr1113672616AG0.00553.FALSEAluJbSINE,Alu
chr3101405563AG0.00511RPL24-FALSE
chr2114352238GA1.72390E-05WASH2P+FALSE
chr5162902516TC0.00226HMMR+FALSE
chr128835934AG0.00069SNHG3,RCC1+TRUEAluSx4SINE,Alu
chr339452123GA0.00093RPSA+FALSE
chr333481400GC1.12603E-05UBP1-FALSE
chr116954981CA0.00876CROCCP2-FALSE
chr275118737CT0.00154HK2+FALSE
chr1148932848AG0.00496LOC645166+FALSE
chr248025764CT0.00722MSH6+FALSE
chr2132481529CT0.00028C2orf27A+FALSE
chr2155555207AC0.00073KCNJ3+FALSE
chr224224040AG0.00882.FALSEAluSpSINE,Alu
chr1740176809AT0.00860NKIRAS2+FALSEAluSzSINE,Alu
chr126755536AG0.00515LIN28A+TRUEAluScSINE,Alu
chr120976163CT0.00174PINK1,PINK1-AS+,-FALSEAluSzSINE,Alu
chr1269237077AG0.00445MDM2+TRUE(GA)nSINE,Alu
chr1629454295TC0.00019SMG1P6,BOLA2-SMG1P6-TRUETigger4aSINE,Alu
chr1298942824AG2.17067E-06TMPO+TRUEAluScSINE,Alu
chr937503313AG0.00584POLR1E+TRUEAluJbSINE,Alu
chr125570692CT0.00095RSRP1-FALSE
chr856985612GT0.00028RPS20-FALSE
chr116891340TA0.00404NBPF1-FALSE
chr812880246AG0.00012KIAA1456+TRUEAluJoSINE,Alu
chr2183643905AT0.00113DNAJC10+FALSE
chr125894472CG0.00063LDLRAP1+FALSEMIRbSINE,Alu
chr16283264TC0.00561ICMT-TRUEAluSx3SINE,Alu
chr152520866CT0.00108TXNDC12-FALSE
chr1109855150AC0.00062SORT1-FALSEA-richSINE,Alu
chr117199803CT0.00997LOC440570+FALSE
chrX2824933TC0.00066ARSD-TRUEAluSx1SINE,Alu
chr153679878TC0.00348C1orf123-FALSE
chr3124948047CG0.00285ZNF148-FALSE
chr2206988452AT0.00669NDUFS1-FALSE
chr1142804438GT0.00522.FALSE
chr220818286AC0.00714HS1BP3-FALSE
chr417804785TC0.00273DCAF16-TRUEAluSxSINE,Alu
chr119578192GA0.00246MRTO4+FALSE
chr3196670090GA6.78352E-09NCBP2-AS2+FALSE
chr1950410816GT0.00050IL4I1,NUP62-FALSEAluSzSINE,Alu
chr110518921CT0.00398.FALSEAluSx3SINE,Alu
chr121070971GA0.00944HP1BP3-FALSE
chr1212114662AG0.00858INTS7-FALSE
chr1828571649AT0.00301DSC3-FALSEMER65CSINE,Alu
chr5140594466GA0.00209PCDHB13+FALSE
chr110520219TC0.00201.FALSEAluSxSINE,Alu
chr1226172221TC0.00030SDE2-FALSEL1MEfSINE,Alu
chr1681064611AG0.00075CENPN+TRUEAluSgSINE,Alu
chr1179811337CA0.00670TOR1AIP2-FALSEAluSpSINE,Alu
chr1145688672AT0.00770NBPF20,NBPF10,RNF115+FALSE
chr110520487TC0.00257.FALSEAluSx1SINE,Alu
chr129464350GC0.00209LOC642846+FALSE
chr133148006AG0.00110SYNC,RBBP4+,-FALSEAluSxSINE,Alu
chr155207982CA0.00063MROH7-TTC4,TTC4+FALSE
chr116717888GA0.00979SZRD1+FALSE
chr1022825288GA0.00051PIP4K2A-FALSE
chr1669151495TA0.00304HAS3+FALSE(T)nSINE,Alu
chr147685593AC0.00891TAL1-FALSE(CCACCC)nSINE,Alu
chr5149781426AG0.00977CD74-FALSE
chr4124237124AG0.00119SPATA5+TRUEAluJrSINE,Alu
chr1773886249TC0.00069TRIM65-TRUEFRAMSINE,Alu
chr1156233189CT5.51743E-05SMG5-FALSE
chr128835934AG0.00566SNHG3,RCC1+TRUEAluSx4SINE,Alu
chr1350102992TC0.00956SETDB2-PHF11,PHF11+FALSEL2aSINE,Alu
chr299812988AG0.00474MRPL30+TRUEAluJbSINE,Alu
chr2192555178CT0.00112LOC105747689+FALSE
chr1161932324AG0.00056ATF6+FALSE
chr717384354AG0.00282AHR+TRUEAluSxSINE,Alu
chr330047174AT0.00556RBMS3+FALSE
chr1179070187GA0.00556ABL2-FALSE
chr488061645TA0.00049AFF1+FALSE(TATAT)nSINE,Alu
chr133148214AG0.00295SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr3195963910CT0.00149.FALSE
chr1119245854TC0.00078E2F8-FALSE
chr111347150CA0.00366UBIAD1+FALSE
chr116891340TA0.00724NBPF1-FALSE
chr5140720886AG0.00980PCDHGA1,PCDHGA2+FALSE
chr4119952955CT0.00278SYNPO2+FALSE
chr2242176182GA2.43141E-09HDLBP-FALSE
chr7100804140CT0.00377AP1S1+FALSE
chr457327022AG0.00057PAICS+TRUEAluSx1SINE,Alu
chr1200375837TG0.00429ZNF281-FALSE(T)nSINE,Alu
chr417804847TC0.00306DCAF16-TRUEAluSxSINE,Alu
chr16582527TC0.00139NOL9-TRUEAluSx1SINE,Alu
chr1757279284AG0.00149PRR11+TRUEAluSq2SINE,Alu
chr2201774209TC0.00534.FALSEAluSzSINE,Alu
chr1765334856TC1.38810E-06PSMD12-TRUEAluSqSINE,Alu
chr154691922TA0.00415SSBP3-FALSE
chr111347155CT0.00366UBIAD1+FALSE
chr755433884AC0.00271LANCL2+FALSE
chr11152631CA0.00517SDF4-FALSE
chr147184569GC0.00509EFCAB14-FALSE
chr9102744711AT0.00675ERP44-FALSE
chr2675831GT0.00731TMEM18-FALSE
chr9128729385CA0.00170PBX3+FALSE
chr3179117270TC0.00478GNB4-TRUEAluSzSINE,Alu
chr128824041TA0.00872PHACTR4+FALSEAluSxSINE,Alu
chr1186390303AC0.00455C1orf27+FALSEL1ME3FSINE,Alu
chr1773940094TC0.00557ACOX1-TRUEAluJbSINE,Alu
chr310290511GT0.00289TATDN2+FALSE
chr4140394600GA0.00950RAB33B+FALSE
chr1173387540GA0.00438RAB6A-FALSE
chr1148928344AG0.00608LOC645166+FALSETAR1SINE,Alu
chr349453834CT0.00518TCTA+FALSE
chr2198339559GT0.00712COQ10B+FALSE
chr1144607285AC0.00208NBPF20+FALSE
chr275887834TC0.00024MRPL19+FALSEL1MB4SINE,Alu
chr5174956492AC0.00397SFXN1+FALSE
chrX118920477AT0.00529RPL39-FALSE
chr1120572572CT0.00497NOTCH2-FALSE
chr1235715523AG0.00660GNG4-FALSE
chr165297861TC0.00895RAVER2+FALSE
chr348787684TC0.00813PRKAR2A-TRUEAluSpSINE,Alu
chr128150601AT0.00558STX12+FALSE
chr220648946CT0.00531RHOB+FALSE
chr1919459215CT0.00068MAU2+FALSE
chr131905886CA0.00702SERINC2+FALSE
chr1168524809TC0.00129CPT1A-TRUE
chr133148210AG0.00342SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr439780672CA0.00743UBE2K+FALSE
chr3184766301TC0.00025VPS8+FALSE
chr136067677TC0.00462PSMB2-TRUEAluSzSINE,Alu
chr1623582262TG0.00101UBFD1+FALSE
chr1117618067CT0.00118TTF2+FALSE
chr1061548852GA0.00693CCDC6-FALSE
chr135320644AT0.00627SMIM12-FALSE
chr116703160AT0.00111MRPL17-FALSE
chr1725640011AG0.00228WSB1+TRUEAluSxSINE,Alu
chr1144618201TC2.48995E-05NBPF20,NBPF9+FALSE

Differential Expression Gene Analysis