Dataset Overview
RBPGNL3
Knock-MethodsiRNA
RBP FamilyGN3L_Grn1
Biosample NameATCC ACS-1011
Tissue TypeFibroblast
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceGEO
Profile IDGSE150945
PlatformGPL11154
Pubmed IDN.A.

GNL3 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of GNL3
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of GNL3


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr11118471800TA0.00875ARCN1+FALSEAluSx3SINE,Alu
chr1610625058TC2.66942E-12EMP2-TRUEAluSx3SINE,Alu
chr1245017464TA0.00314HNRNPU,SNORA100-FALSE
chr2057603730AT0.00101.FALSE
chr1201845881AG0.00422IPO9+FALSE
chr193617404TG0.00265TMED5-FALSE
chr2128064423CT0.00063MAP3K2-FALSE
chr117199259GA0.00217LOC440570+FALSE
chr1681064492AG0.00935CENPN+TRUEAluSgSINE,Alu
chr110517538TC0.00840.FALSEAluSx1SINE,Alu
chr1109818158CT4.51493E-05CELSR2+FALSE
chr112401868AC0.00526VPS13D+FALSE
chr110368092AC0.00945KIF1B+FALSE
chr1231468953GA0.00085EXOC8-FALSE
chr35026731CT0.00824BHLHE40+FALSE
chr1134370TC0.00327.FALSEAluSgSINE,Alu
chr1746803538CT0.00492HOXB13-FALSE
chr558267557CT0.00420PDE4D-FALSE
chr127992824GA0.00503IFI6-FALSE
chr133150598TC4.12722E-05SYNC,RBBP4+,-FALSE
chr314986110TC0.00632FGD5-AS1-TRUEFLAM_CSINE,Alu
chr145280500AG0.00857.FALSEAluSxSINE,Alu
chr1113455427TA0.00814SLC16A1-FALSE
chr1118066724AT0.00979MAN1A2+FALSE
chr136068369TC0.00511PSMB2-TRUEAluScSINE,Alu
chr8145159709CA0.00314MAF1+FALSE
chr1203713133GA0.00984ATP2B4+FALSE
chr1109818160TG0.00745CELSR2+FALSE
chr1145281543CT0.00028NBPF20,NOTCH2NL+FALSE
chrX16781156AG0.00061.FALSEAluJoSINE,Alu
chr187573348CA0.00879HS2ST1+FALSE
chr642061234TC0.00170.FALSEAluSx1SINE,Alu
chr127205224TC0.00353.FALSEAluScSINE,Alu
chr765618786AG3.58027E-08CRCP+TRUEAluSx3SINE,Alu
chr147184539CT0.00425EFCAB14-FALSE
chr1100654765TC0.00254DBT-TRUEAluSzSINE,Alu
chr13545183AT0.00347TPRG1L+FALSE
chr1583659319AT0.00130FAM103A1,C15orf40+,-FALSE
chr217962998TA0.01000GEN1+FALSE
chr1753470462CT0.00230MMD-FALSE
chr1154128333TA0.00204TPM3-FALSE
chr1530781885CT0.00380.FALSE
chr484525986GT0.00081GPAT3+FALSE(TTGTT)nSINE,Alu
chr11593750AG0.00191CDK11B,SLC35E2B-FALSE
chr1183218870GT0.00338NMNAT2-FALSE
chr1112003958TA0.00557ATP5F1+FALSEHelitron2Na_MamSINE,Alu
chr3197682718TC0.00163IQCG,RPL35A+,-FALSE
chr5174956493TA0.00466SFXN1+FALSE
chr2174828621AC0.00315SP3-FALSE
chr2158636910GA0.00160ACVR1-FALSE
chr1939874945TC0.00335SAMD4B+FALSE
chr1658054477TC0.00180USB1+FALSE
chr284670484TC0.00324SUCLG1-TRUE
chr1946052975TC0.00652OPA3-TRUEAluSz6SINE,Alu
chr11469782GC0.00544ATAD3A+FALSE
chr3195701388GA0.00274SDHAP1-FALSE
chr2105964472CT0.00398C2orf49+FALSE(TTTCTCC)nSINE,Alu
chr194342564CA0.00098DNTTIP2-FALSE
chr3101399939GT1.18387E-05RPL24-FALSE
chr812879707TG0.00780KIAA1456+FALSE
chr135886030TC0.00606ZMYM4+FALSE
chr111979807CA0.00574KIAA2013-FALSE
chr1120839743CT0.00647FAM72B+FALSE
chr197116159GT0.00368INSR-FALSE
chr11534826CT0.00382FNDC10-FALSE
chr110521162TC0.00911DFFA-TRUEAluYSINE,Alu
chr125170760TA0.00975CLIC4+FALSE
chr1145116141GA0.00266NBPF20,SEC22B+FALSE
chr2217366901AG0.00143.FALSEAluSz6SINE,Alu
chr3176739580TC4.09936E-06TBL1XR1-FALSE
chr133148706AG0.00050SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr3160219095GA0.00620KPNA4-FALSEA-richSINE,Alu
chr16282420TC0.00133ICMT-TRUEAluSzSINE,Alu
chr4190864378TG0.00247FRG1+FALSEGA-richSINE,Alu
chr1565442678TC2.30704E-07CLPX-TRUEAluSg4SINE,Alu
chr1144481235AG1.18230E-05NBPF20+FALSE
chr186815303TC0.00571ODF2L-FALSE
chr1121133770AG2.59811E-05SRGAP2-AS1,SRGAP2B,SRGAP2C+,-FALSEL1MB4SINE,Alu
chr116932428CG0.00620NBPF1-FALSEL1MC2SINE,Alu
chr642857179CA0.00492RPL7L1+FALSEAluSpSINE,Alu
chr1298943162AG5.01524E-05TMPO+TRUEAluSzSINE,Alu
chr532586387TC0.00569SUB1+FALSE
chr120976023TC0.00889PINK1,PINK1-AS+,-FALSEAluSzSINE,Alu
chr5156905300AC0.00870ADAM19-FALSEMER92BSINE,Alu
chr2198416735TG0.00257HSPE1-MOB4,MOB4+FALSE
chr345721874AG0.00314LIMD1,LIMD1-AS1+,-FALSEAluJbSINE,Alu
chr3129152089GA0.00154MBD4-FALSE
chr157002773AG0.00162PLPP3-FALSE
chr145975279TC0.00019MMACHC+FALSEAluSg7SINE,Alu
chr1115313038GA0.00144SIKE1-FALSE
chr1230975454AG0.00438C1orf198-FALSE
chr1419684445AG0.00351DUXAP10+FALSE
chr162627191AG0.00146PATJ+TRUEAluSxSINE,Alu
chr237331125TC0.00036.FALSEAluSx1SINE,Alu
chr1942375586AG0.00404.FALSEAluSxSINE,Alu
chr7300181GA2.39021E-07FAM20C+FALSE
chr110517313TC0.00015.FALSEAluJrSINE,Alu
chr345721922AG0.00181LIMD1,LIMD1-AS1+,-FALSEAluJbSINE,Alu
chr344790879TC0.00453KIAA1143-TRUEAluYSINE,Alu
chr1490509582TC0.00017TDP1+FALSE
chr133068221AG0.00448ZBTB8A+TRUEAluYSINE,Alu
chr349395691CT0.00037GPX1-FALSE(GCC)nSINE,Alu
chr76063283CT0.00032AIMP2,EIF2AK1+,-FALSE
chr1470838324TC0.00011SYNJ2BP-COX16,SYNJ2BP-TRUEAluSgSINE,Alu
chr3140695493CA0.00559SLC25A36+FALSE
chr534906547TC0.00051RAD1-TRUEAluJoSINE,Alu
chr1144868170CT0.00750NBPF20,PDE4DIP+,-FALSE
chr1144053567CT0.00963.FALSE
chr132801745AG0.00357MARCKSL1-FALSE
chr729961437TG6.91541E-06SCRN1-FALSE
chr1015120306TC0.00323ACBD7-TRUEL1PA7SINE,Alu
chr124934236AG0.00596NCMAP+TRUEAluSz6SINE,Alu
chr721941583CA0.00499CDCA7L-FALSE
chr2025427856AG0.00094GINS1+FALSEAluSzSINE,Alu
chr128833494GA0.00122SNHG3,RCC1+FALSE
chr16282383TC0.00130ICMT-TRUEAluSzSINE,Alu
chr1100615003GA0.00046TRMT13,LRRC39+,-FALSE
chr744917406TC0.00021PURB-TRUEAluSzSINE,Alu
chr187328397AT0.00252SEP15-FALSE
chrX123045342AG0.00381XIAP+FALSE(ATAA)nSINE,Alu
chr1168213516AG0.00233.FALSEAluSx1SINE,Alu
chr194335333GT0.00510DNTTIP2-FALSE
chr3195242526CT3.14972E-05PPP1R2-FALSE
chr3100467676AT0.00288TFG+FALSE
chr178142911TC0.00925ZZZ3-TRUEAluSxSINE,Alu
chr1424760808CT0.00203DHRS1-FALSE
chr315114317TC0.00113RBSN-TRUEAluYSINE,Alu
chr1179989742GC0.00019CEP350+FALSE
chr2217366499AG0.00063.FALSEAluSzSINE,Alu
chr116933629AG0.00299NBPF1-FALSEGA-richSINE,Alu
chr1959095573AG0.00169CENPBD1P1+TRUEAluJbSINE,Alu
chr4109733172TC0.00480COL25A1-FALSE
chr199672919TC0.00097.FALSEAluSx3SINE,Alu
chr19163110TC4.21626E-05.FALSEFRAMSINE,Alu
chr121545089CT0.00834ECE1-FALSEAluSx1SINE,Alu
chr128836974AG9.88453E-07SNHG3,RCC1+TRUEAluScSINE,Alu
chr116893686GC0.00296NBPF1-FALSE
chr642856105AG0.00972RPL7L1+TRUEAluSzSINE,Alu
chr170833400CT0.00224HHLA3+FALSELTR7SINE,Alu
chr10126677249AT0.00762CTBP2-FALSE
chr5122359498AC0.00038PPIC-FALSE(AC)nSINE,Alu
chr237327666TC0.00028.FALSE
chr128662105AG9.98367E-05MED18+TRUEAluSq2SINE,Alu
chr1089623860CG0.00071PTEN+FALSE(CGG)nSINE,Alu
chr3195694454CT0.00307SDHAP1-FALSE
chr1145273345TC0.00133NBPF20,NOTCH2NL+FALSE
chr187573327TC0.00571HS2ST1+FALSE(AT)nSINE,Alu
chr2277003AG1.77913E-11ACP1+FALSE
chr116889642TC6.70250E-05NBPF1-TRUE
chr9132575828AT0.00445TOR1A-FALSE
chr110518052TC0.00791.FALSEAluJrSINE,Alu
chr340577755AG0.00044ZNF621+TRUEAluSzSINE,Alu
chr642856954AG0.00037RPL7L1+TRUEAluSpSINE,Alu
chr2208619742AG1.70106E-07CCNYL1+TRUEAluJbSINE,Alu
chr136067817TC7.91657E-05PSMB2-TRUEAluSzSINE,Alu
chr124861704GA0.00345RCAN3+FALSE
chr1150937771TA0.00026CERS2-FALSE(ATTTTTT)nSINE,Alu
chr1338936619GT0.00212UFM1+FALSE
chr19160958TC3.87385E-05.FALSEAluJbSINE,Alu
chr1541597437TA0.00217.FALSEAluSz6SINE,Alu
chr4248840AG0.00655ZNF876P+TRUEAluYk3SINE,Alu
chr128835937AG2.00244E-07SNHG3,RCC1+TRUEAluSx4SINE,Alu
chr255462751TA0.00613RPS27A+FALSE
chr1450361171CT0.00017ARF6+FALSE(T)nSINE,Alu
chr131426815AG0.00797PUM1-FALSE
chr195362952TC0.00155CNN3-FALSE
chr1171558516CT4.87297E-05PRRC2C+FALSE
chr3195243006CA7.17300E-06PPP1R2-FALSE
chr13731965GA0.00209CEP104-FALSE
chr349067308GA0.00278QRICH1-FALSE
chr1298942886AG1.80851E-07TMPO+TRUEAluScSINE,Alu
chr23592615TC0.00331RNASEH1-TRUEAluSz6SINE,Alu
chr1728575454AC0.00470BLMH-FALSE
chr132661600CT0.00235TXLNA+FALSE(T)nSINE,Alu
chr197084638AG0.00024ZNF557+TRUEAluJbSINE,Alu
chr1231398555AG0.00401GNPAT+FALSE
chr3183901281GA4.84515E-09AP2M1+FALSE
chr5133738270TC0.00067CDKN2AIPNL-TRUEFRAMSINE,Alu
chr145476889CG0.00969HECTD3-FALSE
chr237872508GA5.12140E-05CDC42EP3-FALSE
chr285548076AT0.00682TGOLN2-FALSE
chr1179042300CA0.00491FAM20B+FALSE
chr12124146067AG1.77884E-06GTF2H3+TRUEAluSx4SINE,Alu
chr2217366626AG0.00057.FALSEAluSzSINE,Alu
chr440138676AG0.00157N4BP2+FALSE
chr146075664AG0.00045NASP+TRUEAluSx4SINE,Alu
chr133149508AG0.00871SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr1740176809AT0.00860NKIRAS2+FALSEAluSzSINE,Alu
chr842043493GA0.00045PLAT-FALSEMLT2C1SINE,Alu
chr1146650337GT0.00589PDIA3P1+FALSE
chr375779644CA0.00177ZNF717-FALSE
chr116952298AC2.15086E-05CROCCP2-FALSE
chr140537937AC0.00091CAP1+FALSE(A)nSINE,Alu
chr2130900880CT0.00044CCDC74B-FALSE
chr2196600548GT0.00036SLC39A10+FALSE
chr261278030AG0.00218PEX13+TRUEAluYSINE,Alu
chr6150045919TC0.00206NUP43-TRUEAluSqSINE,Alu
chr3123368013AG0.00812MYLK-FALSE
chr116892276TC0.00236NBPF1-FALSE
chr12104186946GT0.00523NT5DC3-FALSE
chr579923998TC0.00753DHFR-TRUEAluSpSINE,Alu
chr11595540TC0.00042CDK11B,SLC35E2B-TRUEAluJrSINE,Alu
chr165897981GA0.00653LEPR,LEPROT+FALSE
chr1144595935GA0.00061NBPF20+FALSEAluJbSINE,Alu
chr1095163809GT0.00453MYOF-FALSE
chr3195964298AG0.00263.FALSE
chr398518157AT8.60022E-05DCBLD2-FALSE
chr1211918115CT0.00979LPGAT1-FALSEMER63DSINE,Alu
chr1740466890GT0.00260STAT3-FALSEAluSc8SINE,Alu
chr417803537TC7.44979E-05DCAF16-TRUEAluYSINE,Alu
chr299812978AG0.00167MRPL30+TRUEAluJbSINE,Alu
chr4124237124AG0.00119SPATA5+TRUEAluJrSINE,Alu
chr417628548AG0.00991.FALSEAluSzSINE,Alu
chr133147915AG6.77632E-09SYNC,RBBP4+,-FALSEAluSxSINE,Alu
chr613788297TC0.00077MCUR1-TRUEAluSxSINE,Alu
chr3195694454CT0.00092SDHAP1-FALSE
chr1148010972AG0.00068NBPF8-FALSE
chr146269493GC0.00233MAST2+FALSE
chr1116237496TA0.00934VANGL1+FALSE
chr136067784TC0.00083PSMB2-TRUEAluSzSINE,Alu
chr1206579936AG0.00424SRGAP2+FALSE
chr1913054924AC0.00982CALR+FALSE
chr16283305TC0.00554ICMT-TRUEAluSx3SINE,Alu
chr1012292344AG0.00434CDC123+FALSE
chr119984461CT0.00090MINOS1-NBL1,NBL1+FALSE
chr417803748TA0.00859DCAF16-FALSE
chr16259025CT0.00700RPL22-FALSE
chr3196080528TC0.00700UBXN7-TRUEAluSxSINE,Alu
chr373115786TC3.88619E-05PPP4R2+FALSE
chr16283260TC0.00054ICMT-TRUEAluSx3SINE,Alu
chr11647814TC8.49337E-05CDK11B,CDK11A-FALSE
chrX24095066GT0.00603EIF2S3+FALSE
chr1178887208AT0.00239RALGPS2+FALSE

Differential Expression Gene Analysis