Dataset Overview
RBP
MBNL3
Knock-Method
shRNA
RBP Family
zf-CCCH
Biosample Name
SMMC-7721
Tissue Type
Liver
Biosample Type
Cell line
# of Control
1
# of Treat
1
Species
Human
Data Source
GEO
Profile ID
GSE95778
Platform
GPL16791
Pubmed ID
N.A.
MBNL3 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of MBNL3
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
CFI
0.66
4.39
2.79856
0.00199
1.00000
CTSS
3.74
0.89
-1.98811
0.02499
1.00000
DNAJC12
3.83
13.91
1.82770
0.03460
1.00000
GJB3
7.51
1.86
-2.04345
0.01903
1.00000
IFIT2
66.23
20.72
-1.70456
0.04633
1.00000
IGFBP1
5.2
1.57
-1.75614
0.04268
1.00000
KRT34
12.45
3.5
-1.86243
0.03103
1.00000
LXN
3.05
17.71
2.52349
0.00442
1.00000
MARCH4
1.07
0.29
-1.91477
0.02981
1.00000
MBNL3
39.46
3.31
-3.38004
0.00021
1.00000
Showing 1 to 10 of 20 entries
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Function Analysis of Target Genes of MBNL3
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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100
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AAMDC
77589747_77589802_77587995_77588095_77611616_77611778
0.00003
-1.0
DataSet_02_63
View details
AAMDC
77595825_77595962_77587993_77588095_77611616_77611817
0.00085
-0.8
DataSet_02_63
View details
ABCB6
220075655_220075830_220075102_220075545_220077108_220077213
0.00026
-0.75
DataSet_02_63
View details
ABCB6
220081373_220081554_220081085_220081187_220082391_220082529
0.00871
0.138
DataSet_02_63
View details
ABCD4
74756729_74756821_74756003_74756222_74756993_74757155
0.00002
-1.0
DataSet_02_63
View details
ABCD4
74766852_74766971_74765880_74766378_74769577_74769621
0.00004
-1.0
DataSet_02_63
View details
ABHD11
73151550_73151690_73151258_73151440_73151891_73152065
0.00212
0.667
DataSet_02_63
View details
ABHD11
73151550_73151721_73151258_73151440_73151891_73152065
0.00070
0.8
DataSet_02_63
View details
ABHD18
128922870_128922915_128905493_128905578_128930074_128930153
0.00355
-0.315
DataSet_02_63
View details
ABI1
27065993_27066170_27059173_27059274_27112066_27112234
0.00085
-0.8
DataSet_02_63
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Showing 1 to 10 of 1,475 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABI1
27044583_27044670_27047990_27048164_27040526_27040712
0.00878
-0.345
DataSet_02_63
View details
ABI1
27044583_27044670_27047990_27048167_27040526_27040712
0.00609
-0.223
DataSet_02_63
View details
AC107983.2
18424392_18424459_18427090_18427191_18422795_18422988
0.00002
-1.0
DataSet_02_63
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AC107983.2
18427090_18427191_18431886_18432061_18424392_18424459
0.00379
-0.667
DataSet_02_63
View details
ACY1
52019376_52019481_52019867_52019962_52019222_52019287
0.00008
-1.0
DataSet_02_63
View details
AMT
49458924_49459005_49459536_49459704_49457643_49457775
0.00004
1.0
DataSet_02_63
View details
ANKMY1
241448764_241448872_241451277_241451418_241446976_241447108
0.00379
0.667
DataSet_02_63
View details
ANKS3
4776659_4776781_4776979_4777178_4774750_4774832
0.00198
-0.429
DataSet_02_63
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ATXN3
92559595_92559662_92562436_92562481_92555073_92555161
0.00004
1.0
DataSet_02_63
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C18orf8
21086933_21087018_21089156_21089243_21084334_21084411
0.00994
-0.503
DataSet_02_63
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Showing 1 to 10 of 114 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABHD11
73151550_73152065_73151891_73152065_73151258_73151440
0.00377
0.5
DataSet_02_63
View details
ABR
961083_961285_961209_961285_960237_960342
0.00299
0.6
DataSet_02_63
View details
AC005562.1
28958772_28958945_28958772_28958913_28960115_28960408
0.00911
0.11
DataSet_02_63
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ACSF2
48538602_48538731_48538602_48538648_48538993_48539047
0.00717
-0.522
DataSet_02_63
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ACSF3
89160216_89160404_89160216_89160400_89164998_89165171
0.00006
-1.0
DataSet_02_63
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AFG3L1P
90048180_90048331_90048180_90048326_90050938_90051007
0.00160
-0.51
DataSet_02_63
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ALS2CL
46722989_46723088_46722993_46723088_46722735_46722897
0.00937
0.327
DataSet_02_63
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ANKRD54
38228964_38229213_38229165_38229213_38228643_38228751
0.00583
0.353
DataSet_02_63
View details
AP4M1
99699502_99700016_99699502_99699612_99700297_99700404
0.00085
0.8
DataSet_02_63
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APLP2
129939788_129939977_129939788_129939932_129979323_129979497
0.00082
0.581
DataSet_02_63
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Showing 1 to 10 of 176 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AC097662.1
228144198_228144294_228144198_228144291_228146419_228146505
0.00004
-1.0
DataSet_02_63
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ACBD4
43213866_43214143_43214058_43214143_43213474_43213599
0.00002
-1.0
DataSet_02_63
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ACSL4
108926364_108926895_108926364_108926781_108976367_108976554
0.00004
-0.8
DataSet_02_63
View details
ACTG1
79478213_79478829_79478213_79478652_79478928_79479168
0.00989
-0.267
DataSet_02_63
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ADA
43251469_43251719_43251469_43251571_43252842_43252970
0.00174
0.5
DataSet_02_63
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ADAMTSL5
1511623_1511771_1511623_1511726_1512961_1513018
0.00004
1.0
DataSet_02_63
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ADCY10P1
41076687_41077643_41077451_41077643_41076043_41076248
0.00007
-1.0
DataSet_02_63
View details
ADGRG1
57685096_57685534_57685154_57685534_57684164_57684263
0.00007
1.0
DataSet_02_63
View details
ALDH7A1
125929042_125929139_125929042_125929096_125929799_125929959
0.00581
-0.341
DataSet_02_63
View details
AMPD3
10524267_10524441_10524329_10524441_10523016_10523137
0.00007
-1.0
DataSet_02_63
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Showing 1 to 10 of 307 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACADVL
7123440_7123995_7123440_7123516_7123922_7123995
0.00457
-0.311
DataSet_02_63
View details
ADAMTS1
28210757_28212081_28210757_28210933_28211905_28212081
0.00954
0.444
DataSet_02_63
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ADHFE1
67356601_67356983_67356601_67356655_67356828_67356983
0.00003
1.0
DataSet_02_63
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AL162258.1
153604509_153604716_153604509_153604539_153604630_153604716
0.00215
-0.45
DataSet_02_63
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AMT
49456403_49459005_49456403_49457775_49458924_49459005
0.00045
0.667
DataSet_02_63
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AMT
49459536_49459884_49459536_49459704_49459793_49459884
0.00002
-1.0
DataSet_02_63
View details
APBB3
139941171_139941812_139941171_139941307_139941684_139941812
0.00007
-1.0
DataSet_02_63
View details
ARAP1
72398483_72398783_72398483_72398547_72398732_72398783
0.00035
-0.8
DataSet_02_63
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ARHGAP26
142586762_142587038_142586762_142586873_142587008_142587038
0.00000
-0.889
DataSet_02_63
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ARHGEF1
42396095_42396444_42396095_42396194_42396401_42396444
0.00137
-0.556
DataSet_02_63
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Showing 1 to 10 of 173 entries
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Differential Variants in RNA (DVRs)
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Search:
Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
179989742
G
C
9.63603E-05
CEP350
+
FALSE
chr1
154323598
T
A
0.00198
ATP8B2
+
FALSE
(TA)n
SINE,Alu
chr1
143464946
T
C
0.00109
.
FALSE
chr1
154128837
G
T
0.00032
TPM3
-
FALSE
chr1
16889642
T
C
0.00017
NBPF1
-
TRUE
chr1
28566461
T
C
1.61071E-05
.
FALSE
AluSx1
SINE,Alu
chr1
201488771
A
G
0.00062
.
FALSE
AluSq2
SINE,Alu
chr1
11847902
C
A
0.00364
C1orf167,MTHFR
+,-
FALSE
chr1
45976723
T
C
0.00239
MMACHC,PRDX1
+,-
FALSE
chr1
134370
T
C
0.00327
.
FALSE
AluSg
SINE,Alu
Showing 1 to 10 of 291 entries
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression