Dataset Overview
RBPMBNL3
Knock-MethodshRNA
RBP Familyzf-CCCH
Biosample NameSMMC-7721
Tissue TypeLiver
Biosample TypeCell line
# of Control1
# of Treat1
SpeciesHuman
Data SourceGEO
Profile IDGSE95778
PlatformGPL16791
Pubmed IDN.A.

MBNL3 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of MBNL3
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of MBNL3


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr248602186AG0.00870FOXN2+FALSE
chr357611237AG9.49839E-05DENND6A,PDE12+,-FALSE
chr1226809316GA0.00150ITPR2-FALSE
chr1179989742GC9.63603E-05CEP350+FALSE
chr1154323598TA0.00198ATP8B2+FALSE(TA)nSINE,Alu
chr47761211CT8.70555E-11AFAP1,AFAP1-AS1+,-FALSE
chr1765334767TC3.33546E-08PSMD12-TRUEAluSqSINE,Alu
chr1143464946TC0.00109.FALSE
chr1154128837GT0.00032TPM3-FALSE
chr1541591418AG6.38388E-06OIP5-AS1+TRUEAluSxSINE,Alu
chr356655865AG0.00970FAM208A-FALSE(A)nSINE,Alu
chr116889642TC0.00017NBPF1-TRUE
chr721941583CA0.00499CDCA7L-FALSE
chr237331627TC0.00910.FALSEAluJbSINE,Alu
chr128566461TC1.61071E-05.FALSEAluSx1SINE,Alu
chr2134728113AG0.00531IFNAR1+TRUEAluScSINE,Alu
chr1201488771AG0.00062.FALSEAluSq2SINE,Alu
chr111847902CA0.00364C1orf167,MTHFR+,-FALSE
chr42940430TC2.47251E-05NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr9136897584CA0.00060BRD3-FALSEA-richSINE,Alu
chr145976723TC0.00239MMACHC,PRDX1+,-FALSE
chr1134370TC0.00327.FALSEAluSgSINE,Alu
chr11419678AG0.00558ATAD3B+TRUEAluYk2SINE,Alu
chr817089564TC0.00165CNOT7-FALSE
chr11255402CG0.00785CPSF3L-FALSE(GCAGG)nSINE,Alu
chr126144435CG0.00129SEPN1+FALSE
chr1490865627TC0.00162CALM1+FALSE
chr514769103GA0.00104ANKH-FALSE
chr144088547CA0.00927PTPRF+FALSEA-richSINE,Alu
chr1160990878CT9.31086E-06F11R-FALSE
chr133148736AG0.00849SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr237331038TC4.65669E-05.FALSEAluSx1SINE,Alu
chr1160967890TC0.00871F11R-TRUEAluSpSINE,Alu
chr120826788AT6.12716E-05MUL1-FALSE
chr1015120275TC0.00017ACBD7-TRUEL1PA7SINE,Alu
chr110517314TC0.00368.FALSEAluJrSINE,Alu
chr3156258319TC0.00012SSR3-TRUEAluYk3SINE,Alu
chr9117050998GA0.00326COL27A1+FALSE
chr121806710TG0.00194NBPF3+FALSE
chr1474431191AG0.00670ENTPD5-FALSE
chr1780280865GA0.00984SECTM1-FALSE
chr132799530CA8.96009E-06MARCKSL1-FALSE
chr116958064AG2.44983E-05.FALSE
chr138326774TC0.00664INPP5B-TRUEAluJrSINE,Alu
chr314986461TC3.09385E-06FGD5-AS1-TRUEAluSq2SINE,Alu
chr1100489297GC0.00669SLC35A3+FALSEAluScSINE,Alu
chr7100031495CT0.00475MEPCE+FALSE
chr256150864CT0.00615EFEMP1-FALSE
chr1117648269GA0.00988.FALSEAluSz6SINE,Alu
chr537291386TC1.33550E-08.FALSEAluSx3SINE,Alu
chr237330540TC0.00854.FALSEAluSq2SINE,Alu
chr1109535128GA0.00063WDR47-FALSE
chr193308173TG0.00380FAM69A-FALSE
chr4119555142AG4.95460E-05LOC729218+FALSE
chr1153609268GA0.00263CHTOP+FALSE
chr119586458AG0.00053MRTO4+TRUEAluSzSINE,Alu
chr1145322843CT0.00271NBPF20,NBPF10+FALSE
chr1774560725TC0.00476SNHG16+FALSETHE1BSINE,Alu
chr3195694465TC0.00300SDHAP1-FALSE
chr11118888992CG0.00222RPS25-FALSE
chr1089623858GC0.00086PTEN+FALSE(CGG)nSINE,Alu
chr2178129412GT0.00071NFE2L2-FALSE(CGG)nSINE,Alu
chr1463841400AC0.00122PPP2R5E-FALSE
chr2218571477AG4.57932E-05PEX26+TRUEAluSzSINE,Alu
chr598109389TC0.00234RGMB+FALSE
chr1120612163CA0.00812NOTCH2-FALSE
chr237331525TC0.00020.FALSEAluJbSINE,Alu
chr1061548852GA0.00693CCDC6-FALSE
chr1145689537AG0.00028NBPF20,NBPF10+TRUEAluSgSINE,Alu
chr16279957AG0.00814RNF207+TRUEAluSpSINE,Alu
chr5139931626TG0.00490SRA1-FALSE
chr12125512218AG0.00392.FALSEAluSx1SINE,Alu
chr167874689TC0.00896SERBP1-TRUEAluSx3SINE,Alu
chr2151326173AC0.00143RND3-FALSE
chr2206987629TC0.00491.FALSEAluJbSINE,Alu
chr417802819TC0.00747DCAF16-TRUEAluSzSINE,Alu
chr120238574CT6.32696E-05OTUD3+FALSE
chr116946266GC0.00750CROCCP2-FALSEMIRbSINE,Alu
chr111979814GA0.00041KIAA2013-FALSE
chr3196670099AC6.06146E-06NCBP2-AS2+FALSE
chr116945409TA0.00290CROCCP2-FALSE
chr19329105TA0.00233H6PD+FALSE
chr765992794TC0.00820.FALSEAluJrSINE,Alu
chr1145369709AG0.00019NBPF20,NBPF10+TRUEL1MC4SINE,Alu
chr556559238TC0.00149GPBP1+FALSE
chr344485914TC0.00920ZNF445-FALSEMIRbSINE,Alu
chr641900765AG0.00256BYSL+FALSE
chr126143725AT0.00920SEPN1+FALSEAluSxSINE,Alu
chr328390351AG0.00200AZI2-FALSE
chr439551166TC0.00309UGDH-AS1,SMIM14+,-FALSEAluSzSINE,Alu
chr1109181317CG0.00166FAM102B+FALSE
chr123636875TA0.00686HNRNPR-FALSE
chr110521172TC0.00178DFFA-TRUEAluYSINE,Alu
chr193617406AT0.00275TMED5-FALSE
chr356654600CG2.66528E-07CCDC66,FAM208A+,-FALSE
chr11595048TC0.00399CDK11B,SLC35E2B-TRUEAluSgSINE,Alu
chr136388202TG0.00707AGO1+FALSE(GCCT)nSINE,Alu
chr12133298423AG2.89213E-13PGAM5+TRUEAluSpSINE,Alu
chr274442548CT0.00035.FALSE
chr11595077TC0.00031CDK11B,SLC35E2B-TRUEAluSgSINE,Alu
chr2206981874TC0.00060.FALSEAluJbSINE,Alu
chr12336210CT0.00206RER1+FALSE
chr352028445CT0.00934RPL29-FALSE
chr574063154CG0.00255GFM2,NSA2+,-FALSE
chr11594977TC0.00075CDK11B,SLC35E2B-TRUEAluSgSINE,Alu
chr239212563GT9.15843E-06SOS1-FALSE
chr1117532372GT0.00678PTGFRN+FALSE
chr5130537666AG9.26326E-06LYRM7+TRUEAluJbSINE,Alu
chr1162354204CA0.00193C1orf226+FALSE
chr1155161737GC0.00482MUC1-FALSE
chr1772206017TA6.66319E-05RPL38+FALSE
chr1081114959CT0.00048PPIF+FALSEMSTASINE,Alu
chr161411034AG0.00322GNPTG+TRUEAluSzSINE,Alu
chr2196999052CG0.00358STK17B-FALSEMER1BSINE,Alu
chr1150704486TC0.00947CTSS-TRUEAluJoSINE,Alu
chr9115446668TC1.81109E-05INIP-TRUEAluJrSINE,Alu
chr16259025CT0.00700RPL22-FALSE
chr1688789699AC0.00936PIEZO1-FALSE
chr16282224TC0.00062ICMT-TRUEAluSzSINE,Alu
chr578532658CT0.00882JMY+FALSE
chr1453242746TC0.00051GNPNAT1-TRUEAluJrSINE,Alu
chr1233021934AG0.00035PKP2-FALSE
chr1563988357CG0.00539HERC1-FALSE
chr1574319808AG0.00011PML+TRUEAluJrSINE,Alu
chr1143915879AC0.00097.FALSE
chr642855972AG0.00182RPL7L1+TRUEAluSzSINE,Alu
chr6160100931TC0.00215SOD2-TRUEAluSzSINE,Alu
chr1109474776AG0.00088GPSM2,CLCC1+,-FALSEAluSzSINE,Alu
chr237328034TC0.00047.FALSE
chr1109793319CT0.00027CELSR2+FALSE
chr1155181396AG0.00209MTX1+FALSE
chr775958129TA0.00162YWHAG-FALSE
chr177759578AG0.00283AK5+FALSE
chr19328242AG0.00018H6PD+TRUEAluJrSINE,Alu
chr23627302AT0.00021RPS7+FALSE
chr111347150CA0.00016UBIAD1+FALSE
chr11419746AG0.00016ATAD3B+TRUEAluYk2SINE,Alu
chr310193796AG0.00493VHL+TRUEAluSxSINE,Alu
chr1153907287GC0.00122DENND4B-FALSE(CTG)nSINE,Alu
chr442088291CA0.00000SLC30A9+FALSE
chr1233514975GT0.00584MLK4+FALSE
chr110517659TC0.00679.FALSEAluSx1SINE,Alu
chr189447720GA0.00521KYAT3,RBMXL1-FALSE
chr934088016GA0.00226DCAF12-FALSE
chr417488244GA0.00030QDPR-FALSE
chr170718278CG0.00663.FALSE
chr8145159709CA0.00314MAF1+FALSE
chr1154128839GT0.00579TPM3-FALSE
chr16282318TC0.00418ICMT-TRUEAluSzSINE,Alu
chr274381319CA0.00912MOB1A-FALSEAluYSINE,Alu
chr339452123GA0.00093RPSA+FALSE
chr647501448TC0.00017CD2AP+FALSE
chr136068281TC0.00201PSMB2-TRUEAluScSINE,Alu
chr1773886212TC0.00724TRIM65-TRUEFRAMSINE,Alu
chr136068210TC0.00119PSMB2-TRUEAluScSINE,Alu
chr1220231330TC0.00427RNU5F-1,BPNT1+,-FALSEAluYSINE,Alu
chr16585215CT0.00286NOL9-FALSEFAMSINE,Alu
chr7129472355GC0.00246UBE2H-FALSE
chr3192515557GA0.00130MB21D2-FALSE
chr116893721AC0.00179NBPF1-FALSE
chr128825760AG0.00802PHACTR4+TRUEAluSpSINE,Alu
chr11653046TA0.00686CDK11B,CDK11A-FALSE
chr110520378TC0.00145.FALSEAluSx1SINE,Alu
chr811701429TC0.00496CTSB-TRUEAluSx1SINE,Alu
chr16684049GA5.41898E-05PHF13+FALSE
chr1179045672GA0.00411FAM20B+FALSE
chr2120439459CA0.00273TMEM177+FALSE
chr2112874290AT0.00455TMEM87B+FALSE
chr1145116141GA0.00266NBPF20,SEC22B+FALSE
chr116912029CG0.00699NBPF1-FALSE
chr856985609GT0.00134RPS20-FALSE
chr8145159712AG0.00402MAF1+FALSE
chr1582336939GA2.47536E-05MEX3B-FALSE
chr1161732461GT2.02182E-05FTH1-FALSE
chr2240954005CA0.00021NDUFA10-FALSE
chr456295160TA0.00576CLOCK-FALSE(T)nSINE,Alu
chr110043053AG0.00318NMNAT1+TRUEAluScSINE,Alu
chr210198113CA0.00893CYS1-FALSE
chr254896395AC0.00051SPTBN1+FALSE
chr917829GA0.00142WASH1-FALSE
chr12133298355AG0.00024PGAM5+TRUEAluSpSINE,Alu
chr1591044384TG0.00440IQGAP1+FALSE
chr1179829093TC0.00056TOR1AIP2-TRUEAluJrSINE,Alu
chr126755209AG0.00745LIN28A+FALSEAluSx1SINE,Alu
chr3197682718TC0.00163IQCG,RPL35A+,-FALSE
chr146077218AG0.00783NASP+TRUEAluSc8SINE,Alu
chr1100550370TA0.00308SASS6-FALSE
chrX123046779AG0.00629XIAP+TRUEAluSzSINE,Alu
chr145244413TA0.00748.FALSE
chr176227022AG0.00035ACADM+FALSE
chr642856100AG0.00048RPL7L1+TRUEAluSzSINE,Alu
chr363996262CT0.00681PSMD6-AS2,PSMD6+,-FALSE
chr19163402TC0.00014.FALSEAluSpSINE,Alu
chr921863621CA0.00123MTAP+FALSEAluYSINE,Alu
chr261150192CA0.00436REL+FALSEAluSz6SINE,Alu
chr2204162277AG0.00097CYP20A1+TRUEAluSxSINE,Alu
chr1109474776AG0.00149GPSM2,CLCC1+,-FALSEAluSzSINE,Alu
chr1225683182CT0.00056ENAH-FALSE
chr1088951001GA0.00033FAM35A+FALSE
chr16282420TC0.00779ICMT-TRUEAluSzSINE,Alu
chr8128944717GT0.00091PVT1+FALSE
chr1179042550AG0.00831FAM20B+TRUEAluSx1SINE,Alu
chr631324078GT0.00480.FALSE
chr3100083460GA0.00041TOMM70-FALSEFAMSINE,Alu
chr248025764CT0.00722MSH6+FALSE
chr1120164552GA0.00023ZNF697-FALSE
chr3195412864GA0.00725SDHAP2+FALSE
chr146782446AG0.00145UQCRH+FALSE
chr128825337AG0.00838PHACTR4+TRUEAluSgSINE,Alu
chr116945504CT0.00995CROCCP2-FALSE
chr1244572645TG0.00218ADSS-FALSE
chr499801986CA0.00687EIF4E-FALSE
chr115993514CT6.34808E-08.FALSEAluSx4SINE,Alu
chr642856056AG0.00602RPL7L1+TRUEAluSzSINE,Alu
chr536143392CT0.00151LMBRD2-FALSE
chr128661831AG9.37902E-09MED18+TRUEAluSgSINE,Alu
chr11169728GT0.00745B3GALT6+FALSE
chr1111721354GT0.00616CEPT1+FALSE
chr1065380587AG0.00344REEP3+FALSE
chr151873951GA0.00588EPS15-FALSE
chr111782984AG0.00107.FALSEAluSxSINE,Alu
chr63022544TC0.00440HTATSF1P2-TRUEAluJrSINE,Alu
chr2045839074AT0.00019ZMYND8-FALSE(T)nSINE,Alu
chr1113212976CT0.00332CAPZA1+FALSE
chr1113213009AT0.00556CAPZA1+FALSE
chr933046889TA0.00932SMU1-FALSEAluSzSINE,Alu
chr116929327CT0.00304NBPF1-FALSEERVL-E-intSINE,Alu
chr150883798TC0.00156DMRTA2-FALSE
chr2128952006AG0.00076UGGT1+TRUEAluSx1SINE,Alu
chr11419752AG7.69134E-06ATAD3B+TRUEAluYk2SINE,Alu
chr1168523016TC0.00016CPT1A-TRUEAluYSINE,Alu
chr1167396055TA0.00031POU2F1+FALSE
chr42940125TC4.75438E-05NOP14-AS1,NOP14+,-FALSEAluSpSINE,Alu
chr1144833405CA0.00345NBPF20+FALSEL1MEcSINE,Alu
chr228639641CG0.00431.FALSE
chr261370704TA0.00747LOC339803-FALSE
chr1109465168TA0.00246GPSM2+FALSE
chr119953130TA0.00595MINOS1,MINOS1-NBL1+FALSE
chr160340527GA0.00027HOOK1+FALSE
chr425278988TC2.09007E-08PI4K2B+FALSE
chr110520378TC0.00047.FALSEAluSx1SINE,Alu
chr1742877749TC0.00287GJC1-TRUEAluSgSINE,Alu
chr3167727417CT2.31470E-08GOLIM4-FALSE
chr16585331TC0.00779NOL9-TRUEFAMSINE,Alu
chr6108364582TC0.00577OSTM1-FALSE
chr116861718CT0.00891LOC100132147-FALSE
chr110042955AG0.00131NMNAT1+TRUEAluScSINE,Alu
chr1552840681CT0.00789ARPP19-FALSEAluSx1SINE,Alu
chr5151041873AG0.00136SPARC-FALSE
chr159124223GA0.00327MYSM1-FALSEMIR3SINE,Alu
chr6109784327TC0.00854MICAL1,ZBTB24-TRUEAluSgSINE,Alu
chr1180169330CT0.00374FLJ23867+FALSEMIRSINE,Alu
chr9133579734AG0.00129EXOSC2+TRUEAluSx3SINE,Alu
chr146075715AG0.00401NASP+TRUEAluSx4SINE,Alu
chr146077345AG0.00024NASP+TRUEAluSc8SINE,Alu
chr136392543GT0.00971.FALSE(T)nSINE,Alu
chr264069566AG0.00075UGP2+FALSE
chr1112170157CG0.00335RAP1A+FALSEL1ME4aSINE,Alu
chr136068184TC0.00150PSMB2-TRUEAluScSINE,Alu
chr110520258TC0.00152.FALSEAluSxSINE,Alu
chr167874859TC0.00374SERBP1-TRUEAluSxSINE,Alu
chr1204524555AG1.07581E-05MDM4+TRUEAluYSINE,Alu
chr167896025GA5.77574E-06SERBP1-FALSE
chr2128949342AG0.00397UGGT1+TRUEAluSgSINE,Alu
chr128825465AG0.00756PHACTR4+TRUEAluSgSINE,Alu
chr5121362874AG0.00607SRFBP1+TRUEFRAMSINE,Alu
chr1144912233CT0.00066NBPF20,PDE4DIP+,-FALSE
chr110519912TC0.00737.FALSEAluJrSINE,Alu
chr12131356731TC2.96756E-07RAN+FALSE(GGCCGG)nSINE,Alu
chr1534634033AG0.00939NOP10-FALSE
chr1241795525AG0.00165OPN3,CHML-FALSETHE1BSINE,Alu
chr345267321CT0.00059TMEM158-FALSE
chr9125609943AG0.00247.FALSE
chr117393889AG0.00390PADI2-FALSE
chr2025427823AG0.00054GINS1+TRUEAluSzSINE,Alu
chr42940486TC7.87098E-05NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr11252248AG0.00055CPSF3L-FALSEAluSxSINE,Alu
chr273460316GT0.00368PRADC1-FALSE(CGGCGC)nSINE,Alu
chr119943823CA0.00752MINOS1,MINOS1-NBL1+FALSE
chr136067817TC0.00938PSMB2-TRUEAluSzSINE,Alu
chr121101368TC0.00031HP1BP3-TRUEAluScSINE,Alu
chr1193055149AG0.00340TROVE2+FALSE
chr593018884AC0.00030FAM172A-FALSE(TCA)nSINE,Alu
chr7143003526AT0.00050CASP2+FALSEAluYSINE,Alu
chr116891365GA0.00609NBPF1-FALSE
chr1205739266CT0.00125RAB29-FALSE
chr116889596TC0.00093NBPF1-TRUE
chr116890320TC0.00045NBPF1-FALSE
chr187811100AT0.00084LMO4+FALSE
chr1956090351CT1.52943E-09ZNF579-FALSE
chr1958356376AG0.00061ZNF587B+TRUEAluSxSINE,Alu

Differential Expression Gene Analysis