Dataset Overview
RBP
MSL3
Knock-Method
shRNA
RBP Family
Tudor-knot
Biosample Name
CH1
Tissue Type
Ovary
Biosample Type
Cell line
# of Control
3
# of Treat
3
Species
Human
Data Source
GEO
Profile ID
GSE117480
Platform
GPL16791
Pubmed ID
N.A.
MSL3 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of MSL3
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A2M
12.01
3.43
-2.01197
0.00678
1.00000
AC138430.4
0.47
0.21
-1.19400
0.03852
1.00000
ADAMTS9
15.94
29.34
0.83953
0.03786
1.00000
ADCY7
7.58
10.12
0.54504
0.04125
1.00000
ALDOC
91.87
51.42
-0.61933
0.01926
1.00000
ANXA1
63.76
101.71
0.66892
0.02334
1.00000
ARL4C
15.55
26.53
0.77165
0.01547
1.00000
AUTS2
77.79
55.55
-0.51209
0.03082
1.00000
BAMBI
28.29
58.97
1.05586
0.01680
1.00000
C3
0.97
1.91
1.06286
0.04201
1.00000
Showing 1 to 10 of 99 entries
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Function Analysis of Target Genes of MSL3
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AAMDC
77552064_77552106_77532174_77532287_77553524_77553674
0.00193
0.492
DataSet_02_67
View details
AAMDC
77566390_77566528_77553524_77553674_77580767_77580863
0.00033
0.134
DataSet_02_67
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AASDH
57248642_57248763_57244313_57244630_57253527_57253589
0.00000
0.598
DataSet_02_67
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ABCC10
43398485_43398604_43395705_43395877_43399879_43399914
0.00272
-0.063
DataSet_02_67
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ABHD14B
52005475_52005908_52003958_52004200_52007980_52008047
0.00146
0.324
DataSet_02_67
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AC005520.1
74389195_74389400_74388768_74388909_74390097_74390225
0.00718
0.153
DataSet_02_67
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AC244153.1
36607549_36607637_36606637_36606967_36607869_36608000
0.00394
0.255
DataSet_02_67
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ACAD8
134128408_134128518_134123462_134123603_134128901_134128978
0.00858
-0.2
DataSet_02_67
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ACSL4
108939372_108939425_108926364_108926895_108976367_108976442
0.00212
0.328
DataSet_02_67
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ADD1
2911065_2911158_2910241_2910331_2916610_2916767
0.00194
0.139
DataSet_02_67
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Showing 1 to 10 of 531 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ARIH2
48960180_48960244_48964894_48965246_48956253_48956431
0.00171
-0.28
DataSet_02_67
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BCL2L13
18171751_18171908_18178906_18178976_18165979_18166087
0.00226
-0.209
DataSet_02_67
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BORA
73305418_73305525_73309097_73309143_73303063_73303231
0.00517
0.087
DataSet_02_67
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CADM1
115069125_115069158_115080293_115080377_115049363_115049495
0.00097
-0.069
DataSet_02_67
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CBWD5
70475018_70475078_70475443_70475489_70473436_70473474
0.00206
-0.485
DataSet_02_67
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CD44
35219667_35219793_35232792_35232996_35211381_35211612
0.00001
-0.542
DataSet_02_67
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CNOT2
70679179_70679366_70687850_70688074_70671911_70672054
0.00230
0.417
DataSet_02_67
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CPSF4
99047898_99047994_99048324_99048418_99045743_99045896
0.00509
0.171
DataSet_02_67
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CTSB
11715366_11715449_11719853_11719987_11710837_11710988
0.00005
0.333
DataSet_02_67
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DDX5
62500339_62500436_62500794_62500960_62500100_62500234
0.00229
0.098
DataSet_02_67
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Showing 1 to 10 of 56 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ADD1
2910241_2911158_2910241_2910331_2916610_2916767
0.00452
0.149
DataSet_02_67
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ALDH16A1
49964875_49965293_49964875_49965057_49965826_49966012
0.00003
-0.536
DataSet_02_67
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AMPH
38467437_38468885_38468349_38468885_38466553_38466586
0.00092
-0.152
DataSet_02_67
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AP1G2
24036805_24036992_24036947_24036992_24036319_24036528
0.00031
-0.588
DataSet_02_67
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ARFIP1
153701088_153701378_153701088_153701243_153750776_153750878
0.00000
-0.12
DataSet_02_67
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ATP5S
50789228_50789524_50789228_50789437_50790662_50790834
0.00167
0.433
DataSet_02_67
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BOC
112935033_112935267_112935033_112935125_112968568_112968746
0.00536
-0.152
DataSet_02_67
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C11orf57
111946290_111946374_111946290_111946367_111948938_111949039
0.00843
-0.322
DataSet_02_67
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CBX1
46153350_46153540_46153362_46153540_46152367_46152462
0.00461
-0.348
DataSet_02_67
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CCNDBP1
43478017_43478431_43478017_43478077_43481396_43481478
0.00129
0.328
DataSet_02_67
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Showing 1 to 10 of 77 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABHD11
73152657_73152793_73152657_73152772_73152975_73153182
0.00396
-0.333
DataSet_02_67
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ADCY10P1
41076687_41077643_41077451_41077643_41076043_41076248
0.00079
-0.298
DataSet_02_67
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ADSSL1
105205991_105206153_105206086_105206153_105205664_105205715
0.00006
-0.122
DataSet_02_67
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AGTRAP
11805986_11806280_11806183_11806280_11805859_11805894
0.00008
0.454
DataSet_02_67
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AGTRAP
11806044_11806280_11806183_11806280_11805859_11805894
0.00018
0.367
DataSet_02_67
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ALDH7A1
125929042_125929139_125929042_125929096_125929799_125929959
0.00003
-0.398
DataSet_02_67
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ALKBH6
36501468_36501585_36501468_36501547_36501795_36501947
0.00116
-0.39
DataSet_02_67
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ALKBH6
36501639_36501979_36501639_36501947_36502305_36502366
0.00058
-0.579
DataSet_02_67
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APBB1
6422803_6422924_6422803_6422918_6423311_6423439
0.00043
0.299
DataSet_02_67
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ARAP3
141041250_141041822_141041250_141041356_141044488_141044652
0.00068
-0.228
DataSet_02_67
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABCC5
183701540_183705705_183701540_183702682_183705557_183705705
0.00836
0.107
DataSet_02_67
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AL096870.2
24684757_24685003_24684757_24684868_24684942_24685003
0.00018
0.366
DataSet_02_67
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AMDHD2
2570769_2571124_2570769_2570906_2570984_2571124
0.00268
0.264
DataSet_02_67
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AP4M1
99699502_99700016_99699502_99699591_99699868_99700016
0.00008
-0.5
DataSet_02_67
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ARL16
79649063_79650624_79649063_79650156_79650565_79650624
0.00736
0.064
DataSet_02_67
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ATXN2L
28847253_28847806_28847253_28847443_28847769_28847806
0.00128
-0.164
DataSet_02_67
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B4GALNT4
375638_375956_375638_375773_375846_375956
0.00008
-0.303
DataSet_02_67
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B9D1
19246482_19247170_19246482_19246808_19247102_19247170
0.00003
-0.344
DataSet_02_67
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CDK11A
1635661_1636094_1635661_1635783_1635988_1636094
0.00022
-0.281
DataSet_02_67
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CEP170
243349080_243349724_243349080_243349374_243349560_243349724
0.00400
-0.214
DataSet_02_67
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
54563156
A
G
3.59804E-06
TCEANC2
+
FALSE
chr1
10518734
T
C
0.00249
.
FALSE
AluSx1
SINE,Alu
chr1
16958063
C
T
0.00246
.
FALSE
chr1
10521126
T
C
0.00560
DFFA
-
TRUE
AluY
SINE,Alu
chr1
9664845
C
T
1.14015E-08
TMEM201
+
FALSE
chr1
45975348
T
C
0.00062
MMACHC
+
FALSE
AluSg7
SINE,Alu
chr1
93826609
T
G
0.00073
DR1
+
FALSE
chr1
46076529
A
G
0.00336
NASP
+
TRUE
AluSx
SINE,Alu
chr1
1594940
T
C
0.00115
CDK11B,SLC35E2B
-
TRUE
AluSg
SINE,Alu
chr1
6283306
T
C
0.00609
ICMT
-
TRUE
AluSx3
SINE,Alu
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression