Dataset Overview
RBPNRDE2
Knock-MethodsiRNA
RBP FamilyNRDE-2
Biosample NameHela
Tissue TypeCervix
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceGEO
Profile IDGSE120206
PlatformGPL20795
Pubmed ID30842217

NRDE2 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of NRDE2
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of NRDE2


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr457326873AG0.00342PAICS+TRUEAluSx1SINE,Alu
chr345126558CT0.00000CDCP1-FALSE
chr11683565GA7.19943E-05NADK-FALSE
chr11595006TC0.00156CDK11B,SLC35E2B-TRUEAluSgSINE,Alu
chr11344893AG0.00186.FALSEAluSgSINE,Alu
chr1179044181AG0.00790FAM20B+TRUEAluSxSINE,Alu
chr132697085TC0.00366EIF3I+FALSEAluSpSINE,Alu
chr159121768GC0.00196MYSM1-FALSE
chr226616356AG0.00030EPT1+FALSE
chr1145586403GT0.00075NBPF20,NBPF10,PIAS3+FALSE
chr135649803AC0.00659SFPQ-FALSE
chr145244414TA0.00750.FALSE
chr1773940888TC2.69053E-06ACOX1-TRUEAluSx1SINE,Alu
chr116945027TC0.00483CROCCP2-FALSEL1ME3CzSINE,Alu
chr3183900729TC0.00074AP2M1+FALSEMIR3SINE,Alu
chr1541593352AG0.00083.FALSEAluSz6SINE,Alu
chr631321806CT6.66134E-15.FALSE
chr124710405AG0.00246STPG1-FALSE
chr116133987TC0.00830UQCRHL-FALSE
chr76501833AT0.00032KDELR2-FALSE
chr568738649AT0.00716.FALSE
chr18045340CA0.00242PARK7+FALSE
chr120976023TC6.30669E-06PINK1,PINK1-AS+,-FALSEAluSzSINE,Alu
chr10126677249AT0.00762CTBP2-FALSE
chr110520072TC0.00529.FALSEAluSxSINE,Alu
chr8144662353GA0.00951EEF1D-FALSE
chr42940347TC1.36349E-05NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr136032230CA0.00297NCDN+FALSE
chr1145369354CT0.00872NBPF20,NBPF10+FALSE
chr633281842GT0.00514.FALSE
chr264687777GT7.38315E-07LGALSL+FALSE
chr1183515428GA0.00232SMG7+FALSE
chr1585184841TC0.00016WDR73,SCAND2P+,-FALSEAluSzSINE,Alu
chr1148251079TC0.00880NBPF8,NBPF14,NBPF9-FALSEL1MC4SINE,Alu
chr424801315GA9.79732E-09SOD3+FALSE
chr136068370TC3.60077E-09PSMB2-TRUEAluScSINE,Alu
chr153290298AG0.00258ZYG11B+TRUEAluSg4SINE,Alu
chr195660026GT0.00129TMEM56-RWDD3,LOC101928118,TMEM56+,-FALSE
chr144463185TG0.00969SLC6A9-FALSE
chr1149818441TC0.00773.FALSEMLT1DSINE,Alu
chr1463841400AC0.00122PPP2R5E-FALSE
chrX77083538TC0.00055MAGT1-TRUEAluSz6SINE,Alu
chr176229120TC0.00309ACADM+FALSE
chr116524869TC0.00164ARHGEF19-FALSE
chr1206566948GA0.00879SRGAP2+FALSE
chr8144681777GT0.00383TIGD5+FALSE
chr328390351AG1.14010E-06AZI2-FALSE
chr167874697TC0.00010SERBP1-TRUEAluSx3SINE,Alu
chr136068210TC0.00178PSMB2-TRUEAluScSINE,Alu
chr146751319GA0.00085LRRC41-FALSE
chr110521170TC0.00498DFFA-TRUEAluYSINE,Alu
chr398516118TA0.00541DCBLD2-FALSE
chr348787219AG0.00024PRKAR2A-FALSE
chr116945570AG0.00157CROCCP2-FALSE
chr119953120GA0.00024MINOS1,MINOS1-NBL1+FALSE
chr116932429CG0.00106NBPF1-FALSEL1MC2SINE,Alu
chr1145282600AC0.00391NBPF20,NOTCH2NL+FALSEMER126SINE,Alu
chr1184762498TC0.00834FAM129A-TRUEAluSzSINE,Alu
chr145975670AG0.00530MMACHC+TRUEAluSx4SINE,Alu
chr1160966352TC1.19601E-07F11R-TRUEAluSgSINE,Alu
chr190401562CA0.00057LRRC8D+FALSE
chr210586903AC0.00041ODC1,SNORA80B-FALSE
chr119586437AG0.00056MRTO4+TRUEAluSzSINE,Alu
chr1227953266GT0.00198KLHL42+FALSE
chr417803604TC0.00174DCAF16-TRUEAluYSINE,Alu
chr773150511TC0.00414ABHD11-FALSE
chr116203171CT3.13656E-06SPEN+FALSE
chr473923056TC0.00077COX18-TRUEAluSzSINE,Alu
chr261405795GT0.00061AHSA2+FALSE
chr1749041897TC4.67707E-06SPAG9-TRUEAluSxSINE,Alu
chr116889663AG0.00392NBPF1-FALSE
chr7128169979TG0.00569.FALSE
chr1159946750GA0.00105LINC01133+FALSE(GAAA)nSINE,Alu
chr1965489CA0.00494WASH5P-FALSEL2bSINE,Alu
chr220401855GA0.00107SDC1-FALSE
chr1145281656AT0.00768NBPF20,NOTCH2NL+FALSE
chr1234744480GA0.00409IRF2BP2-FALSE
chr153679610GA0.00084CPT2+FALSEAluSzSINE,Alu
chr577655378TC0.00555SCAMP1-AS1-TRUEAluSx4SINE,Alu
chrX123046695AG0.00054XIAP+TRUEAluSzSINE,Alu
chr135816903CT0.00174ZMYM4+FALSE
chr12109887765TG0.00091KCTD10-FALSE
chr237328097TC3.71887E-07.FALSE
chr1211920314TC0.00938LPGAT1-FALSE
chr126143725AT0.00112SEPN1+FALSEAluSxSINE,Alu
chr1244572644GC0.00088ADSS-FALSE
chr1204525666AG0.00093MDM4+TRUEAluSzSINE,Alu
chr126901090CT0.00056RPS6KA1+FALSE
chr261152521GA0.00134REL+FALSE
chr116932144AC7.50683E-06NBPF1-FALSE
chr1193466866GT0.00559MIR1304-FALSEAluJrSINE,Alu
chr1146651038TG0.00964PDIA3P1+FALSE
chr457796758TA6.82460E-05REST+FALSE
chr540832549CT2.26031E-05RPL37-FALSE
chr152817504TC0.00934CC2D1B-TRUEAluSg4SINE,Alu
chr344791351TC0.00497KIAA1143-TRUEAluJrSINE,Alu
chr817503270GC0.00410MTUS1-FALSE
chr1256215103AT0.00353DNAJC14-FALSE
chr310193796AG0.00493VHL+TRUEAluSxSINE,Alu
chr1741144251TG0.00014RUNDC1+FALSE
chr1475202856AG3.12821E-09FCF1+TRUEAluSxSINE,Alu
chr1135017260TC0.00224PDHX+FALSE
chr1880052CT0.00231NOC2L-FALSE
chr240336210CT0.00828SLC8A1-AS1+FALSE
chr1165764473CG0.00403EIF1AD-FALSEAluSz6SINE,Alu
chr2231375015AT0.00990TUG1+FALSE
chr133149414AG5.81443E-05SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr2018468512TC0.00072RBBP9-TRUEAluSz6SINE,Alu
chr657034841GT0.00581ZNF451,LOC101927211+,-FALSE
chr2174773510TA0.00775SP3-FALSEA-richSINE,Alu
chr1423441380TC0.00102AJUBA-TRUEEutr2SINE,Alu
chr11252468TC0.00182CPSF3L-TRUEAluJrSINE,Alu
chr1143189473CA0.00572LOC102723769-FALSE
chr3179506482AG0.00017USP13+FALSEMER33SINE,Alu
chr8144940798TC0.00255EPPK1-FALSE
chr6160526910AT0.00672IGF2R+FALSE
chr10101992810TC0.00456CWF19L1-TRUEAluJbSINE,Alu
chr116932783GC0.00843NBPF1-FALSEL1MC2SINE,Alu
chr5154194459CA0.00832LARP1+FALSE
chr116889414TC0.00679NBPF1-TRUEL1MC4SINE,Alu
chr1180247483TC0.00167.FALSE
chr119542458TC1.01966E-05LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr9131071425AT0.00068TRUB2-FALSE
chr119466935TG0.00439IPO7+FALSE
chr297494866CT0.00069CNNM3+FALSE
chr310192744AG3.36147E-05VHL+TRUEAluSx1SINE,Alu
chr642857057AG0.00020RPL7L1+TRUEAluSpSINE,Alu
chr9115446747TC0.00648INIP-TRUEAluJrSINE,Alu
chr314528004TC0.00091SLC6A6+FALSE
chr344772983CT0.00795ZNF501+FALSE
chr1179326315AG0.00187SOAT1+TRUE
chr721941583CA0.00499CDCA7L-FALSE
chr1712915009GA0.00219ELAC2-FALSE
chr642856978AG0.00819RPL7L1+TRUEAluSpSINE,Alu
chr2176791759AC0.00232LNPK-FALSEL2bSINE,Alu
chr499801986CA0.00687EIF4E-FALSE
chr101086804TA0.00821IDI2-AS1,IDI1+,-FALSE
chr11595540TC0.00042CDK11B,SLC35E2B-TRUEAluJrSINE,Alu
chr1168218660AG0.00296.FALSEAluSzSINE,Alu
chr861534428AG0.00274RAB2A+FALSE
chr177759578AG0.00031AK5+FALSE
chr720178420TC0.00053MACC1,LOC101927668-TRUEAluYSINE,Alu
chr1184761350TC0.00219FAM129A-TRUEAluJoSINE,Alu
chr2217001882TC0.00996XRCC5+FALSE
chr1234561498TC0.00092TARBP1-FALSE
chr2217366626AG0.00057.FALSEAluSzSINE,Alu
chr1206635244TA0.00195SRGAP2+FALSE
chr182803231AT0.00638SMCHD1+FALSE
chr457326156AG0.00230PAICS+TRUEAluJrSINE,Alu
chr3128215735GA0.00734GATA2-AS1+FALSE
chr3194373832TC0.00053LSG1-FALSE
chr2242212177CT2.31719E-05HDLBP-FALSE
chrX3526615GT0.00820PRKX-FALSE
chr153291395AG0.00323ZYG11B+TRUEAluJrSINE,Alu
chr153680090GA0.00321C1orf123-FALSE
chr3178741082AC5.87013E-06ZMAT3-FALSE
chr120977748TG0.00474PINK1,PINK1-AS+,-FALSE
chr16282426TC0.00043ICMT-TRUEAluSzSINE,Alu
chr286364710TC0.00056PTCD3+FALSE
chr345721836AG0.00310LIMD1,LIMD1-AS1+,-FALSEAluJbSINE,Alu
chr5149829072GT0.00816RPS14-FALSE
chr3149686507TC0.00193PFN2-FALSE
chr1155161704GC0.00034MUC1-FALSE
chr4124237124AG0.00119SPATA5+TRUEAluJrSINE,Alu
chr1100657416CT0.00228DBT-FALSEAluJbSINE,Alu
chr8128752685GA2.94991E-09MYC+FALSE
chr136531781GA0.00288.FALSE
chr4177252238AG9.63526E-05SPCS3+TRUE
chr2101186088CT0.00817PDCL3+FALSE
chr115755248CT0.00405EFHD2+FALSE
chr1118167515CT2.81283E-05FAM46C+FALSE
chr237330612TC0.00030.FALSEAluSq2SINE,Alu
chr9139698779CG0.00106CCDC183,CCDC183-AS1+,-FALSEL2bSINE,Alu
chr2174090331AC0.00901ZAK,MLK7-AS1+,-FALSEAluSxSINE,Alu
chr1206579798TC0.00883SRGAP2+FALSE
chr540832551AT0.00394RPL37-FALSE
chr237328013TC1.05952E-05.FALSE
chr537290323TC8.21848E-08.FALSEAluSzSINE,Alu
chr170717293GA0.00716SRSF11+FALSE
chr1727586605GA0.00053NUFIP2-FALSE
chr2218571474AG1.16198E-07PEX26+TRUEAluSzSINE,Alu
chr1013234356AT3.19668E-07MCM10+FALSE
chr124935337AG0.00773NCMAP+TRUEAluJbSINE,Alu
chr59549459AG0.00783SNHG18+FALSE
chr119542464TC0.00140LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr540835321AT0.00526RPL37-FALSE
chr147184569GC0.00509EFCAB14-FALSE
chr1145369480AG7.08400E-07NBPF20,NBPF10+FALSEL1MC4SINE,Alu
chr4152020781CT0.00925RPS3A+FALSE
chr12106460001GA2.23324E-05NUAK1-FALSE
chr3179115501AT1.86203E-06GNB4-FALSE
chr255516940AC0.00389CCDC88A-FALSE(GA)nSINE,Alu
chr764441627GA0.00478ZNF117-FALSE
chr1688789703CG0.00498PIEZO1-FALSE
chr120977380TC0.00429PINK1,PINK1-AS+,-FALSE
chr193803490TC0.00572CCDC18-AS1-FALSEAluJrSINE,Alu
chr116944809GC0.00072CROCCP2-FALSE
chr652860743TG1.01575E-05.FALSE7SKSINE,Alu
chr1207250570AG0.00486PFKFB2+FALSE
chr1161732461GT2.02182E-05FTH1-FALSE
chr46644327AG0.00000MRFAP1+FALSE
chr366430378TA0.00326LRIG1-FALSE
chr3148863151AG0.00062HPS3+FALSE
chr145975628AG0.00465MMACHC+TRUEAluSx4SINE,Alu
chr1109818158CT4.51493E-05CELSR2+FALSE
chr285554792CA0.00634TGOLN2-FALSE
chr1148003756TC0.00162NBPF8-TRUEL1MC4SINE,Alu
chr237331750TC1.79348E-08.FALSEAluJbSINE,Alu
chr632796463AC0.00680.FALSE(CCCCA)nSINE,Alu
chr128920823AG0.00850RAB42+FALSEAluSxSINE,Alu
chr489181477TC7.00483E-05PPM1K-TRUEAluSx1SINE,Alu
chr2113962806AG0.00309.FALSEAluSzSINE,Alu
chr45743512TC0.00210EVC+FALSE
chr1474524774TC0.00906BBOF1,ALDH6A1+,-FALSEAluSc8SINE,Alu
chrX77083007TC0.00371MAGT1-TRUEAluSgSINE,Alu
chr9136217449CG0.00158RPL7A+FALSE
chr128823671TC0.00073PHACTR4+FALSE
chr9135172412AG0.00394SETX-FALSE
chr572801329TA0.00073BTF3+FALSE
chr2204301753TA0.00012RAPH1-FALSE
chr139990456GA0.00749BMP8A,PPIEL+,-FALSEL2bSINE,Alu
chr145975345AG0.00071MMACHC+TRUEAluSg7SINE,Alu
chr237329300TC0.00925.FALSEAluJr4SINE,Alu
chr16582425TC0.00039NOL9-TRUEAluSx1SINE,Alu
chr1218617543GA0.00291TGFB2+FALSE
chr135648712GA0.00298SFPQ-FALSE
chrX152916229GA0.00809DUSP9+FALSE
chr1145688664AT0.00679NBPF20,NBPF10,RNF115+FALSE
chr1060047611GA0.00855CISD1+FALSE(A)nSINE,Alu
chr348784500TA0.00264PRKAR2A-FALSE(T)nSINE,Alu
chr1178887208AT0.00239RALGPS2+FALSE
chr129464178GA0.00081LOC642846+FALSE
chr1246829873GA0.00342CNST+FALSE
chr1101443701AG0.00406SLC30A7+FALSE
chr1565442546TC0.00564CLPX-TRUEAluSg4SINE,Alu
chr1145283733AG0.00458NBPF20,NOTCH2NL+FALSE
chr3108367794GT0.00434DZIP3+FALSE
chrX2824933TC0.00066ARSD-TRUEAluSx1SINE,Alu
chr2176791181TC0.00063LNPK-TRUEMSTDSINE,Alu
chr116892135GA0.00221NBPF1-FALSE
chr120976163CT1.02809E-07PINK1,PINK1-AS+,-FALSEAluSzSINE,Alu
chr1144852203TG0.00518NBPF20,PDE4DIP+,-FALSE
chr1201846630CA0.00041IPO9+FALSE(CA)nSINE,Alu
chr16583383TC0.00305NOL9-TRUEAluSqSINE,Alu
chr11662547TC0.00556SLC35E2-TRUEAluYSINE,Alu
chr848889705AG0.00339MCM4+TRUEAluSx3SINE,Alu
chr47764017TC0.00028AFAP1,AFAP1-AS1+,-FALSE
chr3120114953GA0.00373FSTL1-FALSE
chr5177576458AT0.00427.FALSE
chr1256510708AG0.00050RPL41+FALSE
chr310005650CT0.00698EMC3-FALSE
chr11251841TC0.00915CPSF3L-TRUEAluSq2SINE,Alu
chr1183105534TC0.00424LAMC1+FALSE
chr1666765441GT4.44089E-16DYNC1LI2-FALSEL2cSINE,Alu
chr129519712TC0.00017MECR-TRUEAluJbSINE,Alu
chr119543459TC0.00395LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr170718276GT0.00493.FALSE
chr192917287CA0.00243ZNF57+FALSE
chr139317318CA1.55431E-15RRAGC-FALSE
chr1207247475CA0.00680PFKFB2+FALSEMER5BSINE,Alu
chr110518052TC7.90759E-05.FALSEAluJrSINE,Alu
chr647501448TC0.00017CD2AP+FALSE
chr1158066172CT0.00616KIRREL+FALSE
chr119984461CT0.00090MINOS1-NBL1,NBL1+FALSE
chr237331525TC0.00020.FALSEAluJbSINE,Alu
chr3193385047CT0.00259OPA1+FALSE
chr2232319615AT8.19218E-06NCL-FALSE
chr1145283718GA0.00897NBPF20,NOTCH2NL+FALSE
chr197543764CT0.00840DPYD-FALSE
chr825272447AT0.00770DOCK5+FALSE
chr1150337289GT0.00020RPRD2+FALSE
chr126449882AG0.00783PDIK1L+FALSE
chr439552148TC0.00011UGDH-AS1,SMIM14+,-FALSEAluSxSINE,Alu
chr185787118GC0.00104DDAH1-FALSE
chr2207027628AG0.00022EEF1B2+FALSE
chr131345785TA0.00962SDC3-FALSE
chr16713251AG0.00628WDR90+TRUEAluSxSINE,Alu
chr345748599TA0.00470SACM1L+FALSE
chr2128064448GT0.00602MAP3K2-FALSE(GT)nSINE,Alu
chr229023121GT0.00077PPP1CB+FALSE
chr1249745425AG0.00489DNAJC22+TRUEAluSx3SINE,Alu
chr1657505635GT0.00974POLR2C+FALSE
chr1225683161TG0.00168ENAH-FALSE(T)nSINE,Alu
chr116892275CT0.00230NBPF1-FALSE
chr1144881463CT0.00147NBPF20,PDE4DIP+,-FALSE
chr119934893CA0.00171MINOS1,MINOS1-NBL1,RPS14P3+FALSE
chr119543309TC0.00769LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr895805070AG0.00721DPY19L4+TRUEAluYf1SINE,Alu
chr1942376675AG0.00085.FALSE
chr16583138TC0.00010NOL9-TRUEAluSx4SINE,Alu
chr9125609941GA0.00043.FALSE
chr349460407CT0.00080NICN1-FALSEL2cSINE,Alu
chr1179829595TC0.00188TOR1AIP2-TRUEAluJrSINE,Alu
chr3179117646GA0.00812GNB4-FALSE
chr287755101CT0.00431LINC00152+FALSE
chr124288530AT0.00031PNRC2+FALSE
chr99442082TG0.00052PTPRD-FALSE7SLRNASINE,Alu
chr140537923GA6.08919E-05CAP1+FALSE(A)nSINE,Alu
chr830536078TC5.73232E-10GSR-FALSEAluJrSINE,Alu
chr153712570AC0.00277LRP8-FALSE(CA)nSINE,Alu
chr1944418680GC0.00066ZNF45-FALSE
chr136067752TC0.00031PSMB2-TRUEAluSzSINE,Alu
chr121795388AG0.00790NBPF3+FALSE
chr310193732AG0.00472VHL+TRUEAluJrSINE,Alu
chr1911560483AG0.00775PRKCSH+TRUEAluSxSINE,Alu
chr120976075TC0.00135PINK1,PINK1-AS+,-FALSEAluSzSINE,Alu
chr624720534TC0.00053.FALSE

Differential Expression Gene Analysis