Dataset Overview
RBPZCCHC24
Knock-MethodsiRNA
RBP Familyzf-CCHC_2
Biosample NameMDA-MB-435
Tissue TypeBreast
Biosample TypeCell line
# of Control3
# of Treat3
SpeciesHuman
Data SourceGEO
Profile IDGSE66632
PlatformGPL11154
Pubmed IDN.A.

ZCCHC24 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of ZCCHC24
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of ZCCHC24


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr2207943813GT0.00619KLF7-FALSE(TTTTGT)nSINE,Alu
chr119566382AG0.00513LOC101927895,EMC1+,-FALSE
chr1648388258AG8.02686E-05MIR5095+TRUEAluSzSINE,Alu
chr363997896GA0.00301PSMD6-AS2,PSMD6+,-FALSE
chr339453610CT0.00025RPSA+FALSE
chr643582750AG0.00844POLH+TRUEAluSx1SINE,Alu
chr2128602366TC0.00236.FALSEAluSq2SINE,Alu
chr1954971229TC0.00202LENG8+FALSE
chr110521238TC0.00797DFFA-TRUEAluYSINE,Alu
chr1945406536GT0.00518TOMM40+FALSE
chr7130629624TC0.00435LINC-PINT-TRUE
chr848889672AG0.00091MCM4+TRUEAluSx3SINE,Alu
chr1168218543AG0.00547.FALSEAluSzSINE,Alu
chr110042987AG0.00488NMNAT1+TRUEAluScSINE,Alu
chr135648840GT0.00543SFPQ-FALSEAluSx3SINE,Alu
chr833356827TA0.00122MAK16,TTI2+,-FALSE
chr2233446266CT0.00177EIF4E2+FALSE
chr1144829799GC2.98942E-05NBPF20,NBPF9+FALSEL1MC4SINE,Alu
chr119684006GC0.00396CAPZB-FALSE
chr126449340GA0.00711PDIK1L+FALSE
chr1168218543AG7.78857E-07.FALSEAluSzSINE,Alu
chr1757279284AG0.00149PRR11+TRUEAluSq2SINE,Alu
chr1236714710CT0.00014LGALS8,HEATR1+,-FALSE
chr7105162638GC0.00155PUS7-FALSE
chr150883798TC0.00156DMRTA2-FALSE
chr1180169330CT0.00015FLJ23867+FALSEMIRSINE,Alu
chr1145689717AG7.73781E-05NBPF20,NBPF10+TRUEAluJbSINE,Alu
chr116932495AC0.00385NBPF1-FALSEL1MC2SINE,Alu
chr1610623705TC0.00011EMP2-TRUEAluSpSINE,Alu
chr2217366868AG0.00100.FALSEAluSz6SINE,Alu
chr11534614TC5.67045E-11FNDC10-FALSE
chr176227022AG0.00759ACADM+FALSE
chr141204569CT0.00854NFYC+FALSE
chr2232576431TC0.00593PTMA+FALSE
chr1900725TG0.00110KLHL17+FALSE(TTTA)nSINE,Alu
chr1298943182AG1.41026E-08TMPO+TRUEAluSzSINE,Alu
chr5149823795AT0.00261RPS14-FALSE
chr119543349TC2.12419E-08LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr1656510329TG0.00247OGFOD1+FALSE
chr63114457CT0.00320RIPK1+FALSE
chr2187544234CT0.00078ITGAV+FALSE
chr1100440553AG0.00179SLC35A3+TRUEAluJbSINE,Alu
chr4103809328GT0.00284CISD2,SLC9B1+,-FALSE
chr1757279282AG7.34157E-06PRR11+TRUEAluSq2SINE,Alu
chr140537922AG0.00686CAP1+FALSE(A)nSINE,Alu
chr1162299945AC0.00314AHNAK-FALSE
chr110519982TC0.00129.FALSEAluJrSINE,Alu
chr19163383TC0.00383.FALSEAluSpSINE,Alu
chr1115299504GT0.00067CSDE1-FALSE
chr9111781015AC0.00853TMEM245-FALSE
chr237331736TC0.00165.FALSEAluJbSINE,Alu
chr417802824TC0.00594DCAF16-TRUEAluSzSINE,Alu
chr2201774185TC6.12175E-05.FALSEAluSzSINE,Alu
chr1212459257AG0.00068PPP2R5A+FALSE
chr7127947979TC0.00257.FALSEAluJrSINE,Alu
chr128835934AG0.00596SNHG3,RCC1+TRUEAluSx4SINE,Alu
chr61395043TC0.00055FOXF2+FALSE
chr1648387215AG0.00864LONP2,MIR5095+TRUEAluJbSINE,Alu
chr152816691TC0.00353CC2D1B-TRUEAluSx1SINE,Alu
chr2174090321CA0.00273ZAK,MLK7-AS1+,-FALSEAluSxSINE,Alu
chr1101541172AG6.48917E-05LOC102606465+TRUEMLT1KSINE,Alu
chr1776117147GA0.00606TMC6-FALSE
chr579277950CA0.00037MTX3-FALSE(AC)nSINE,Alu
chr417803604TC0.00206DCAF16-TRUEAluYSINE,Alu
chr1205738302GA0.00661RAB29-FALSE
chr1203277243GT1.60795E-05BTG2+FALSE
chr81730491AG5.38446E-06CLN8+TRUEAluSx1SINE,Alu
chr1232532505GA0.00385.FALSE
chr1100490067AG0.00267SLC35A3+TRUEAluSgSINE,Alu
chr237328013TC0.00765.FALSE
chr179108421AT7.77428E-05IFI44L+FALSE
chr133149496AG0.00308SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr1420940606GA0.00710PNP+FALSE
chr1206579798TC0.00476SRGAP2+FALSE
chr136789546AG0.00562EVA1B-FALSEMIRbSINE,Alu
chr744842099AG1.82502E-05PPIA+TRUE
chr46718811AG1.36854E-07BLOC1S4+FALSEFLAM_ASINE,Alu
chr3181430334GA0.00305SOX2-OT,SOX2+FALSE
chr11255400TC0.00224CPSF3L-FALSE
chr1495555551CT0.00404DICER1-FALSE
chr1545775144TC0.00867SLC30A4-TRUEAluJrSINE,Alu
chr23609064GA0.00194RNASEH1-AS1+FALSEMER33SINE,Alu
chr1154128831GT0.00183TPM3-FALSE
chr3183476685GA0.00032YEATS2+FALSE
chr2131104524GA0.00912IMP4+FALSEL1MA9SINE,Alu
chr237331037TC0.00538.FALSEAluSx1SINE,Alu
chr3170113815GT0.00586SKIL+FALSE
chr6150046603TC0.00763NUP43-TRUEAluSq2SINE,Alu
chr2191067766TC0.00034C2orf88+FALSE
chr5137891109CG0.00031HSPA9-FALSE
chr2237035915CG0.00348AGAP1+FALSE
chr764435684TG0.00239ZNF117-FALSE
chr1179832838AG0.00018TOR1AIP2-FALSEMLT1LSINE,Alu
chr4761850TC0.00026PCGF3+FALSE
chr375779573AG0.00530ZNF717-FALSE
chr743665371AT0.00430STK17A,COA1+,-FALSE(AG)nSINE,Alu
chr11597403CT0.00912CDK11B,SLC35E2B-FALSE
chr185113229AG0.00687SSX2IP-FALSE
chr128826085AG0.00212PHACTR4+TRUEAluJbSINE,Alu
chr417802819TC0.00112DCAF16-TRUEAluSzSINE,Alu
chr1145354360AC0.00761NBPF20,NBPF10+FALSE
chr1688789702GA0.00125PIEZO1-FALSE
chr2206983298TC0.00811.FALSEAluJbSINE,Alu
chr8128944719AT0.00093PVT1+FALSE
chr1201438097GC2.75480E-05PHLDA3-FALSE
chr155207986TA0.00872MROH7-TTC4,TTC4+FALSE
chr1205683408CT0.00082NUCKS1-FALSE
chr67310259AG0.00092SSR1-FALSE
chr558267557CT0.00420PDE4D-FALSE
chr7105162562GC0.00096PUS7-FALSE
chr311596302TC0.00110ATG7+FALSE
chr1116609185GA0.00187SLC22A15+FALSE
chr10101563815GA0.00218ABCC2+FALSE
chr274090062TG0.00248STAMBP+FALSE
chr110517313TC0.00015.FALSEAluJrSINE,Alu
chr11607574CT0.00187CDK11B,SLC35E2B-FALSE
chr1225357680TC0.00861ETFRF1+FALSE
chr167874854TC0.00358SERBP1-TRUEAluSxSINE,Alu
chr110520099TC5.82547E-06.FALSEAluSxSINE,Alu
chr315114288TC7.51597E-05RBSN-TRUEAluYSINE,Alu
chr128825331AG0.00024PHACTR4+TRUEAluSgSINE,Alu
chr5134236287AG0.00538TXNDC15+TRUEAluSqSINE,Alu
chr1144932151GT0.00643NBPF20,PDE4DIP+,-FALSE
chr145975574AG0.00613MMACHC+TRUEAluSx4SINE,Alu
chr39848198GT0.00295ARPC4,ARPC4-TTLL3+FALSE(T)nSINE,Alu
chr269689663TC0.00091AAK1-TRUEAluSgSINE,Alu
chr146093409AC0.00383GPBP1L1-FALSEA-richSINE,Alu
chr119984346AG0.00071MINOS1-NBL1,NBL1+FALSE
chr116932428CG0.00197NBPF1-FALSEL1MC2SINE,Alu
chr822111410AG0.00396.FALSEAluSzSINE,Alu
chr237328016TC5.08368E-07.FALSE
chr3150262004AT0.00167SERP1-FALSE
chr1156495521CA0.00097IQGAP3-FALSE
chr34403260CT0.00603SUMF1-FALSE
chr1202992954TC0.00042TMEM183A+FALSE
chr255452459GT5.59903E-07CLHC1-FALSE
chr199673113TC0.00330.FALSEAluSx3SINE,Alu
chr457326126AG0.00017PAICS+TRUEAluJrSINE,Alu
chr1101444791CT0.00268SLC30A7+FALSE
chr830536015TC6.64592E-05GSR-TRUEAluJrSINE,Alu
chr19160989TC0.00609.FALSEAluJbSINE,Alu
chr593018883AT0.00181FAM172A-FALSE(TCA)nSINE,Alu
chr166100980AT0.00033LEPR+FALSE
chr220097874TC0.00769TTC32-FALSE
chr28996878AT9.26766E-05MBOAT2-FALSEAluSzSINE,Alu
chr154691906CG0.00465SSBP3-FALSE
chr128826114AG0.00264PHACTR4+TRUEAluJbSINE,Alu
chr1237064432CG0.00019MTR+FALSE
chr197144886AG0.00078.FALSE
chr154692341TC0.00027SSBP3-FALSE(T)nSINE,Alu
chr136530674AG0.00603.FALSEAluSgSINE,Alu
chr18938276TA0.00178ENO1-FALSE
chr4153701130CT2.11271E-05ARFIP1+FALSE
chr11597403CT0.00015CDK11B,SLC35E2B-FALSE
chr1118472382GT0.00029WDR3+FALSE
chr5131804838AG0.00036C5orf56+TRUEMLT1DSINE,Alu
chr2240954005CA0.00021NDUFA10-FALSE
chr125688276AG0.00015TMEM50A+FALSE
chr1490509564CT0.00552TDP1+FALSE
chr110518052TC0.00179.FALSEAluJrSINE,Alu
chr131905905GC0.00948SERINC2+FALSE
chr2174128513CT0.00069ZAK,MLK7-AS1+,-FALSE
chr2242291743AG0.00731SEPT2+FALSE
chr111721832CG0.00514FBXO44+FALSE
chr237328034TC0.00047.FALSE
chr16583515TC0.00528NOL9-TRUEAluSqSINE,Alu
chr6133135886AG0.00629RPS12+FALSE
chr11344893AG7.94078E-08.FALSEAluSgSINE,Alu
chr3194369580CA0.00042LSG1-FALSE
chr9132266624AG5.52448E-06LINC00963+TRUEAluSxSINE,Alu
chr145975345AG0.00357MMACHC+TRUEAluSg7SINE,Alu
chr146075171AC0.00140NASP+FALSEA-richSINE,Alu
chr6150047376TC0.00612NUP43-TRUEAluScSINE,Alu
chr110520154TC0.00380.FALSEAluSxSINE,Alu
chr1169101269TG0.00207ATP1B1+FALSE(T)nSINE,Alu
chr457326262AG2.33397E-05PAICS+TRUEAluJrSINE,Alu
chr42940438TC0.00151NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr3167727417CT2.31470E-08GOLIM4-FALSE
chr1225977968CT0.00490SRP9+FALSE
chr425749191TC0.00301SEL1L3-FALSE
chr1155161725GA0.00240MUC1-FALSE
chr12125512444AG4.63106E-05.FALSEAluYSINE,Alu
chr439552175TC0.00010UGDH-AS1,SMIM14+,-FALSEAluSxSINE,Alu
chr1207250570AG0.00486PFKFB2+FALSE
chr237331546TC0.00694.FALSEAluJbSINE,Alu
chr1061548852GA0.00693CCDC6-FALSE
chr313670776TC0.00336FBLN2+FALSE
chr1226333556CA0.00250ACBD3-FALSE(CAAAA)nSINE,Alu
chr269746296CT0.00620AAK1-FALSE
chr1158065762CT0.00310KIRREL+FALSE
chr119586501AG2.56701E-06MRTO4+TRUEAluSzSINE,Alu
chr113936953CT0.00515PDPN+FALSE
chr5118174735TC0.00139DTWD2-TRUEAluYSINE,Alu
chr146076529AG0.00196NASP+TRUEAluSxSINE,Alu
chr237076498AC0.00797STRN-FALSE
chr120982216TA0.00065DDOST-FALSE
chr1236208773CT0.00722NID1-FALSE
chr35258985TC0.00436EDEM1+FALSE
chr1109181308TA0.00756FAM102B+FALSE
chr634213986TA0.00262HMGA1+FALSE
chr232535747AG0.00250.FALSEAluJbSINE,Alu
chr112058878TC0.00110MFN2+FALSE
chr2232319578CA0.00844NCL-FALSEA-richSINE,Alu
chr286249840TC0.00482LOC90784-TRUEAluJrSINE,Alu
chr19645101CT0.00726.FALSE(ATATTC)nSINE,Alu
chr1156256064CT0.00619SMG5,TMEM79+,-FALSE
chr345722287AG0.00197LIMD1,LIMD1-AS1+,-FALSEAluSzSINE,Alu
chr3195701388GA0.00274SDHAP1-FALSE
chr140537944CA2.58277E-05CAP1+FALSE
chr1145509570AG0.00306NBPF20,NBPF10,RBM8A+TRUEAluJrSINE,Alu
chr1157963369CG0.00667KIRREL+FALSE
chr187573325CT0.00121HS2ST1+FALSE(AT)nSINE,Alu
chr340577810AG0.00896ZNF621+TRUEAluSzSINE,Alu
chr4190873405CT0.00325FRG1+FALSE
chr110042955AG0.00430NMNAT1+TRUEAluScSINE,Alu
chr1120163247TC0.00010ZNF697-FALSE
chrX84532996TG0.00801POF1B-FALSE
chr1168169452GA0.00600TIPRL+FALSE
chr1153507176CT0.00957S100A6-FALSE
chr3183900836GA0.00658AP2M1+FALSE
chr1165544381TC0.00433AP5B1-TRUEAluJbSINE,Alu
chr540852810GT0.00276CARD6+FALSE
chr193308173TG0.00380FAM69A-FALSE
chr1109181304CA0.00592FAM102B+FALSE
chr738764464TC0.00193VPS41-TRUEAluSpSINE,Alu
chr721941589TA0.00535CDCA7L-FALSE
chr132372387AC0.00757PTP4A2-FALSE(CA)nSINE,Alu
chr439549703TC0.00150UGDH-AS1,SMIM14+,-FALSEAluSpSINE,Alu
chr1115249239GA1.76451E-06NRAS-FALSE
chr323959425CG0.00000RPL15+FALSE
chr5121400545AT0.00740LOX-FALSE
chr226613948AG0.00218EPT1+FALSE
chr110520669TC0.00963DFFA-FALSEAluSc8SINE,Alu
chr139317318CA1.55431E-15RRAGC-FALSE
chr237330620TC0.00216.FALSEAluSq2SINE,Alu
chr133149363AG0.00368SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr116889866GA0.00995NBPF1-FALSE
chr1145512024AG0.00247NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr2128950491AG0.00043UGGT1+TRUEAluScSINE,Alu
chr572801323CA0.00240BTF3+FALSE
chr140307166GA0.00026TRIT1-FALSE
chr178378694AC0.00735MYH10-FALSE
chr153291434AG0.00545ZYG11B+TRUEAluJrSINE,Alu
chr116889639TC0.00524NBPF1-TRUE
chr116889642TC6.70250E-05NBPF1-TRUE
chr2178129405CT0.00295NFE2L2-FALSE(CGG)nSINE,Alu
chr1590815820AG0.00171.FALSEFRAMSINE,Alu
chr817503270GC0.00410MTUS1-FALSE
chr119543249TC1.15194E-07LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr1016554733GT0.00706PTER+FALSE
chr540826638CA0.00749LOC100506548-FALSELTR78SINE,Alu
chr291805928TC0.00000.FALSEMLT1H1SINE,Alu
chr765618876AG0.00817CRCP+TRUEAluSx3SINE,Alu
chr344487862GA0.00262ZNF445-FALSE
chr135644502AT0.00702SFPQ-FALSE(A)nSINE,Alu
chr1206557430CT0.00011SRGAP2+FALSE
chr116893686GC0.00171NBPF1-FALSE
chr152381348TG0.00500RAB3B-FALSE
chr2223765491CT0.00689ACSL3+FALSE
chr133149375AG0.00148SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr274333235CT0.00022TET3+FALSE
chr170718269AG0.00234.FALSE
chr232535568AG0.00016.FALSEMER8SINE,Alu
chr1451387782CT0.00802PYGL-FALSE
chr2128602500TC4.07621E-06.FALSEAluSq2SINE,Alu
chr116910172GA0.00958NBPF1-FALSE
chrM8859GA0.00929.FALSE
chr1210025751GA0.00067DIEXF+FALSETigger4aSINE,Alu
chr237330343CT0.00055.FALSEAluSq2SINE,Alu
chr19162224TC0.00124.FALSEAluSxSINE,Alu
chr110519951TC0.00378.FALSEAluJrSINE,Alu
chr179109337GT0.00790IFI44L+FALSELTR26SINE,Alu
chr1051943605CT0.00508.FALSEMLT1JSINE,Alu
chr2134730108AG0.00680IFNAR1+TRUEAluSg7SINE,Alu
chr1160302244TC0.00310COPA-TRUE
chr1593198678TC0.00064FAM174B-FALSE(GCCGCT)nSINE,Alu
chr237327670TC5.08697E-08.FALSE
chr536143413GA0.00097LMBRD2-FALSE
chr10865825CT0.00088LARP4B-FALSE
chr1206579936AG0.00424SRGAP2+FALSE
chr811701429TC0.00758CTSB-TRUEAluSx1SINE,Alu
chr357882601CT0.00987SLMAP+FALSE
chr410447986TA0.00077ZNF518B-FALSE
chr3178740415GA0.00227ZMAT3-FALSE
chr237327666TC0.00231.FALSE
chr3148748197TA0.00026HLTF-FALSE
chr2035521048AT0.00727TLDC2,SAMHD1+,-FALSE
chr1120611964GC0.00211NOTCH2-FALSE
chr830536015TC0.00286GSR-TRUEAluJrSINE,Alu
chr2035520935TC0.00120TLDC2,SAMHD1+,-FALSEFLAM_ASINE,Alu
chr115755550AC0.00969EFHD2+FALSE
chr11595048TC0.00495CDK11B,SLC35E2B-TRUEAluSgSINE,Alu
chr119586455AG3.44081E-06MRTO4+TRUEAluSzSINE,Alu
chr1116237273AG0.00309VANGL1+FALSE
chr1168218574AG0.00898.FALSEAluSzSINE,Alu
chr2042933642TC0.00275FITM2-TRUEAluJoSINE,Alu
chr133148736AG0.00849SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr3156258227TC0.00094SSR3-TRUEAluYk3SINE,Alu
chr1154128836AT0.00090TPM3-FALSE
chr1269159400GA0.00173SLC35E3+FALSE(AT)nSINE,Alu
chr9115446747TC0.00648INIP-TRUEAluJrSINE,Alu
chr123833608GA0.00890E2F2-FALSE
chr3155572129CT0.00082SLC33A1-FALSE
chr193297609CT8.96972E-06RPL5+FALSE
chr153288924AG1.39497E-05ZYG11B+TRUEAluJoSINE,Alu
chr193298516AG0.00493FAM69A,RPL5+,-FALSE
chr1542860107AG0.00194HAUS2+TRUEAluSgSINE,Alu
chr324019990AG0.00308NR1D2+FALSE

Differential Expression Gene Analysis