Dataset Overview
RBPZEB1
Knock-MethodsiRNA
RBP Familyzf-C2H2
Biosample NameMDA-231-D
Tissue TypeBreast
Biosample TypeCell line
# of Control1
# of Treat2
SpeciesHuman
Data SourceGEO
Profile IDGSE98273
PlatformGPL17303
Pubmed ID28618162

ZEB1 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of ZEB1
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of ZEB1


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr9137330714AC0.00030RXRA+FALSE
chr811172477CT0.00805MTMR9+FALSE
chr2204298783AC0.00179RAPH1-FALSE(AT)nSINE,Alu
chr11650807TC0.00096CDK11B,CDK11A-FALSE
chr110518734TC0.00143.FALSEAluSx1SINE,Alu
chr1269237021AG0.00229MDM2+TRUE
chr128825805GA0.00115PHACTR4+FALSEAluSpSINE,Alu
chr19328120AG1.75282E-05H6PD+TRUEAluJrSINE,Alu
chr121100862CA0.00012HP1BP3-FALSE(AC)nSINE,Alu
chr11595603CG0.00017CDK11B,SLC35E2B-FALSEAluJrSINE,Alu
chr19162932AT0.00635.FALSE
chr1118066459AG0.00729MAN1A2+FALSE
chr128825418AG0.00046PHACTR4+TRUEAluSgSINE,Alu
chr16283306TC0.00505ICMT-TRUEAluSx3SINE,Alu
chr1100440563AG0.00732SLC35A3+FALSEAluJbSINE,Alu
chr5256514GC0.00198SDHA+FALSE
chr116933629AG0.00299NBPF1-FALSEGA-richSINE,Alu
chr7100739267GA0.00654.FALSEAluSxSINE,Alu
chr1144828857CG4.37583E-07NBPF20,NBPF9+FALSE
chr310005392TC8.76084E-06EMC3-FALSEAluSg7SINE,Alu
chr417804785TC0.00273DCAF16-TRUEAluSxSINE,Alu
chr3194998813AG0.00572ACAP2-FALSEAluSx1SINE,Alu
chr1269159400GA0.00173SLC35E3+FALSE(AT)nSINE,Alu
chr452753346AG0.00782DCUN1D4+TRUEAluScSINE,Alu
chr146075191CA0.00056NASP+FALSEA-richSINE,Alu
chr1585184830TC0.00895WDR73,SCAND2P+,-FALSEAluSzSINE,Alu
chr125570565GA0.00244RSRP1-FALSEAluSINE,Alu
chr116909129TC0.00131NBPF1-FALSE
chr1160967857TC0.00806F11R-TRUEAluSpSINE,Alu
chr153289940AG0.00245ZYG11B+TRUEFRAMSINE,Alu
chr1110136683AC0.00183GNAI3+FALSE
chr1160966351TC0.00023F11R-TRUEAluSgSINE,Alu
chr352084040CT4.81509E-06DUSP7-FALSE
chr165898263AG0.00767LEPR,LEPROT+FALSEMIRcSINE,Alu
chr128836872AG0.00019SNHG3,RCC1+TRUEAluScSINE,Alu
chr553842079CT0.00067SNX18+FALSE
chr348894565TA0.00142SLC25A20-FALSE
chr119545142AG0.00071LOC101927895,EMC1+,-FALSE
chr345722396AG0.00231LIMD1,LIMD1-AS1+,-FALSEAluSzSINE,Alu
chr115905501GA0.00359AGMAT-FALSE
chr146016687TC0.00296AKR1A1+FALSE
chr152375564TC0.00866RAB3B-FALSE
chr6108364582TC0.00577OSTM1-FALSE
chr3183900836GA2.54977E-05AP2M1+FALSE
chr146032311AG0.00362AKR1A1+FALSE
chr126774225AG0.00614DHDDS+TRUEAluSz6SINE,Alu
chr131351513GA0.00265SDC3-FALSE
chr12123347005TA0.00268HIP1R+FALSE
chr5149364144AG0.00014SLC26A2+TRUEAluSc8SINE,Alu
chr133148196AG0.00054SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr1119574537GA0.00935WARS2-FALSE
chr144088547CA0.00018PTPRF+FALSEA-richSINE,Alu
chr126449340GA0.00711PDIK1L+FALSE
chr119542354TC0.00684LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr345722396AG0.00337LIMD1,LIMD1-AS1+,-FALSEAluSzSINE,Alu
chr11111431662TA0.00204LAYN+FALSE
chr473923605TC0.00366COX18-TRUEAluSq2SINE,Alu
chr1079800437TA0.00445RPS24+FALSE
chr144438961AG0.00013DPH2+FALSEMER3SINE,Alu
chr1160966352TC3.14235E-07F11R-TRUEAluSgSINE,Alu
chr1109535088GA0.00353WDR47-FALSE
chr2134728068AG0.00188IFNAR1+TRUEAluScSINE,Alu
chr237330172TG0.00972.FALSE
chr136068243TC0.00217PSMB2-TRUEAluScSINE,Alu
chr220449068AG0.00014PUM2-FALSE
chr23193040GA0.00650TSSC1-FALSE
chr128826085AG0.00153PHACTR4+TRUEAluJbSINE,Alu
chr1144618144AG0.00725NBPF20,NBPF9+FALSE
chr13730332TC0.00025CEP104-TRUEAluSx3SINE,Alu
chr19644847AG0.00672.FALSEAluJrSINE,Alu
chr1120539711GT0.00627NOTCH2-FALSE
chr1168220489AG0.00319.FALSEAluSz6SINE,Alu
chr488059663GT0.00165AFF1+FALSE(GT)nSINE,Alu
chr237328075TC0.00335.FALSE
chr138174665GA0.00475CDCA8+FALSE
chr56633042CT0.00377NSUN2-FALSE
chr152498140GA0.00044TXNDC12,KTI12-FALSE
chr10120920588TC0.00304SFXN4-FALSE
chr3196658640CT0.00444SENP5+FALSE
chr116717888GA0.00118SZRD1+FALSE
chr2229890660AG0.00596PID1-FALSE
chr1114940228CT0.00734TRIM33-FALSE(T)nSINE,Alu
chr2232576431TC0.00593PTMA+FALSE
chr13730400TC0.00800CEP104-TRUEAluSx3SINE,Alu
chr345721874AG0.00314LIMD1,LIMD1-AS1+,-FALSEAluJbSINE,Alu
chr1145512073AG0.00056NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr1741133087AG0.00141RUNDC1+FALSE
chr18931947TC0.00059ENO1-FALSE
chr76501831TA0.00110KDELR2-FALSE
chr3105266274TC4.07026E-07ALCAM+FALSE
chr344487862GA0.00262ZNF445-FALSE
chr299812447AG0.00587MRPL30+TRUEAluSxSINE,Alu
chr110519982TC6.11297E-05.FALSEAluJrSINE,Alu
chr11344749AG3.37361E-05.FALSEAluSx1SINE,Alu
chr19331101AG5.45177E-05H6PD+FALSEAluSxSINE,Alu
chr1959093998AG2.36787E-07CENPBD1P1+TRUEAluYSINE,Alu
chr1210416438CA0.00085SERTAD4+FALSE
chr13697486CG0.00110LRRC47-FALSEAluScSINE,Alu
chr635259646GC0.00808ZNF76+FALSE
chr596366330GC0.00251.FALSE(TG)nSINE,Alu
chr2208619742AG0.00500CCNYL1+TRUEAluJbSINE,Alu
chr357126614CT0.00358IL17RD-FALSEAluYSINE,Alu
chr1145689566AG0.00331NBPF20,NBPF10+TRUEAluSgSINE,Alu
chr286252038TC0.00453POLR1A-TRUEAluSq2SINE,Alu
chr324163645CG1.00972E-05THRB-FALSE
chr1236702210AG0.00153LGALS8+FALSE
chr2217366897AG0.00440.FALSEAluSz6SINE,Alu
chr2128063697GA0.00775MAP3K2-FALSE
chr7299843GA6.16222E-05FAM20C+FALSE
chr1245006499CG0.00171COX20+FALSE
chr185786957TG0.00959DDAH1-FALSE
chr1688784415TC0.00750PIEZO1-TRUEAluSx3SINE,Alu
chr1144594308GA0.00577NBPF20+FALSE
chr587566382TA0.00997TMEM161B-AS1+FALSE
chr1100316589AG0.00481AGL+FALSE
chr755433880GC0.00115LANCL2+FALSE
chr345636335AG0.00262LIMD1+FALSE(AC)nSINE,Alu
chr110520331CT0.00280.FALSEAluSx1SINE,Alu
chr132739982GA0.00300LCK+FALSE
chr631506635TG6.78064E-05.FALSE
chr312641718GA0.00091RAF1-FALSE
chr1742876398TC0.00697GJC1-FALSEAluSz6SINE,Alu
chr3195963395AG0.00028.FALSE
chr19328242AG5.63395E-05H6PD+TRUEAluJrSINE,Alu
chr12133298121AG1.85542E-11PGAM5+TRUEAluJoSINE,Alu
chr125570692CT0.00095RSRP1-FALSE
chr193827995CT0.00714DR1+FALSE
chr2128950515AG0.00208UGGT1+TRUEAluScSINE,Alu
chr1100361925GA0.00181AGL+FALSE
chr456236845AG6.76031E-06SRD5A3,SRD5A3-AS1+,-FALSEAluJbSINE,Alu
chr1109746825AG0.00281KIAA1324+TRUEAluJbSINE,Alu
chr286252136TC0.00015POLR1A-TRUEAluSq2SINE,Alu
chr132384710GA0.00299PTP4A2-FALSE
chr116011005GC0.00616PLEKHM2+FALSE(GCG)nSINE,Alu
chr1373651653GT0.00532KLF5+FALSE
chr717384887AG4.32861E-08AHR+TRUEAluScSINE,Alu
chr177124772GA0.00175ACADVL+FALSE
chr127992823AC0.00087IFI6-FALSEFAMSINE,Alu
chr111846092GT0.00877C1orf167,MTHFR+,-FALSE
chr1767538540TC0.00295.FALSE
chr5149829071TC0.00360RPS14-FALSE
chr19198079TC0.00933LINC01002-FALSE
chr1965146GA0.00761WASH5P-FALSE
chr123833607AT0.00890E2F2-FALSE
chr194995491CT0.00036F3-FALSEAluSxSINE,Alu
chr1117530188AG0.00199PTGFRN+FALSE
chr1742877749TC0.00287GJC1-TRUEAluSgSINE,Alu
chr7300181GA2.39021E-07FAM20C+FALSE
chr2232319611AT3.84700E-07NCL-FALSE
chr154692341TC0.00045SSBP3-FALSE(T)nSINE,Alu
chr1949608GA0.00435ISG15+FALSE
chr138155699TG0.00734C1orf109-FALSEAluSx1SINE,Alu
chr2128601464TC0.00161.FALSEAluJrSINE,Alu
chr133961147TG0.00236ZSCAN20+FALSE
chr67310259AG0.00092SSR1-FALSE
chr3100083423TC0.00678TOMM70-FALSEFAMSINE,Alu
chr1472041443CT0.00842SIPA1L1+FALSE
chr125570549CA0.00387RSRP1-FALSE
chr1765335292TC6.31480E-06PSMD12-TRUEAluSxSINE,Alu
chr644222157GA0.00856SLC35B2-FALSE
chr1132625925AG0.00845CCDC73-FALSEAluJbSINE,Alu
chr2178406765TA0.00325AGPS+FALSE
chr119653870TC0.00477PQLC2+FALSE
chr162821989CT0.00709TCEB2-FALSE
chr119542679TC0.00584LOC101927895,EMC1+,-FALSEFRAMSINE,Alu
chr11252221TC0.00728CPSF3L-TRUEAluSxSINE,Alu
chr152520867TA7.48778E-05TXNDC12-FALSE
chr1116239368GA5.97604E-05VANGL1+FALSE
chr185484276CT0.00168MCOLN3-FALSE
chr1121133733GA0.00552SRGAP2-AS1,SRGAP2B,SRGAP2C+,-FALSEL1MB4SINE,Alu
chr856985611AT0.00028RPS20-FALSE
chr3195701389CA0.00227SDHAP1-FALSE
chr152306066TA0.00154NRDC-FALSE(TCA)nSINE,Alu
chr388104072TA0.00815CGGBP1-FALSE
chr1146650542AG0.00017PDIA3P1+FALSE
chr1201438097GC2.75480E-05PHLDA3-FALSE
chr136067760TC0.00768PSMB2-TRUEAluSzSINE,Alu
chr23592638TC0.00164RNASEH1-TRUEAluSz6SINE,Alu
chr8145159706CG0.00561MAF1+FALSE
chr11419768AG0.00250ATAD3B+TRUEAluYk2SINE,Alu
chr3172224303AG0.00524TNFSF10-FALSE
chr572801321TA0.00427BTF3+FALSE
chr184373309TC0.00627TTLL7-FALSE
chr1143398850GT0.00639.FALSE
chr4165998078TC0.00407TMEM192-TRUEAluSxSINE,Alu
chr738764358TC0.00675VPS41-TRUEAluSpSINE,Alu
chr136067925TC1.59250E-07PSMB2-TRUEAluSzSINE,Alu
chr14100762714TC0.00573SLC25A29-TRUEAluJoSINE,Alu
chr145244053AG0.00621RPS8+FALSE
chr3122283289CA0.00072DTX3L,PARP9+,-FALSE
chr1144822066AG0.00020NBPF20,NBPF9+FALSE
chr799017241CA0.00721PTCD1,ATP5J2-PTCD1-FALSE
chr12125511226AG0.00205THRIL-FALSEAluSx1SINE,Alu
chr1656510329TG0.00247OGFOD1+FALSE
chr110517688TC0.00630.FALSEAluSx1SINE,Alu
chr224223256AG0.00711UBXN2A+TRUEAluScSINE,Alu
chr151822219GA0.00223EPS15-FALSE
chr174672926TA0.00159FPGT-TNNI3K,FPGT+FALSEKanga1dSINE,Alu
chr272968438GT0.00147EXOC6B-FALSE
chr112164538GA8.95385E-07TNFRSF8+FALSE
chr457326873AG0.00342PAICS+TRUEAluSx1SINE,Alu
chr59549459AG0.00783SNHG18+FALSE
chr17833544TC0.00186VAMP3+FALSE
chr3195963500CT0.00014.FALSE
chrX77084042TC0.00703MAGT1-TRUEAluSzSINE,Alu
chr1132623987TA5.29256E-06CCDC73,EIF3M+,-FALSE
chr228002603CA0.00010MRPL33+FALSE
chr633384325GT0.00456.FALSE

Differential Expression Gene Analysis