Dataset Overview
RBPHNRNPC
Knock-MethodsiRNA
RBP FamilyRRM_1
Biosample NameHEK293
Tissue TypeKidney
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceGEO
Profile IDGSE56010
PlatformGPL11154
Pubmed ID25719671

HNRNPC - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of HNRNPC
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of HNRNPC


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr1155868177GA7.38851E-05RIT1-FALSE
chr1939440966TC0.00011FBXO17-FALSE
chr1179042697AG0.00092FAM20B+TRUEAluSx1SINE,Alu
chr261278017AG8.96590E-05PEX13+TRUEAluYSINE,Alu
chr1725640295TA0.00154WSB1+FALSE
chr116112795AG0.00106FBLIM1+FALSE
chr175288081CT0.00518RABEP1+FALSE
chr135648712GA0.00298SFPQ-FALSE
chr2152334389AG0.00308.FALSEAluSqSINE,Alu
chr1179045672GA0.00920FAM20B+FALSE
chr195362952TC0.00155CNN3-FALSE
chr152381348TG0.00500RAB3B-FALSE
chr1965146GA0.00761WASH5P-FALSE
chr155316322AG0.00266DHCR24-FALSE
chr178414334CA0.00702FUBP1-FALSEA-richSINE,Alu
chr3119212015GA0.00024POGLUT1+FALSE
chr133149373AG0.00918SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr132799439CT0.00239MARCKSL1-FALSE
chr1145116147TA0.00031NBPF20,SEC22B+FALSE
chr2025427801AG0.00300GINS1+TRUEAluSzSINE,Alu
chr1109818270CT0.00996CELSR2+FALSE
chr110521238TC0.00793DFFA-TRUEAluYSINE,Alu
chr596368471GT3.92809E-06.FALSE
chr233046027GC0.00397TTC27+FALSE
chr220424655GA0.00193SDC1-FALSE
chr1204526648AG0.00302MDM4+TRUEAluSxSINE,Alu
chr146164493TC0.00330IPP-TRUEAluJbSINE,Alu
chr1226809316GA0.00150ITPR2-FALSE
chr138478446CG4.10892E-09UTP11+FALSE
chr1109475629AG0.00305GPSM2,CLCC1+,-FALSEAluJoSINE,Alu
chr1431916927TC1.57126E-05LOC101927124,DTD2+,-FALSEAluSc8SINE,Alu
chr310290512AG0.00289TATDN2+FALSE
chr237329307TC0.00201.FALSEAluJr4SINE,Alu
chr237331275TC0.00884.FALSEAluSx1SINE,Alu
chr7128144035AG0.00054.FALSEAluSq2SINE,Alu
chr1143467373TC0.00182.FALSE
chr237329300TC0.00925.FALSEAluJr4SINE,Alu
chr19161245TC0.00071.FALSEAluSxSINE,Alu
chr124798383CT0.00546NIPAL3+FALSE
chr3169807548TC0.00665PHC3-TRUEAluSx1SINE,Alu
chr349762662GT6.99764E-06IP6K1-FALSE
chr19163328TC0.00287.FALSEAluSpSINE,Alu
chr119984098CG0.00826MINOS1-NBL1,NBL1+FALSE
chr1160967938TC0.00270F11R-TRUEAluSpSINE,Alu
chr11119533726AG0.00169NECTIN1-FALSE
chr310322521TC0.00531TATDN2+FALSE
chr3120046117GT0.00443LRRC58-FALSEAluYi6SINE,Alu
chr1145322843CT0.00271NBPF20,NBPF10+FALSE
chr178414310CA0.00131FUBP1-FALSE
chr1153907287GC0.00159DENND4B-FALSE(CTG)nSINE,Alu
chr12336210CT0.00175RER1+FALSE
chr19815354TG0.00212CLSTN1-FALSE
chr1154438084CT0.00561IL6R+FALSE
chr1533063527CT0.00183FMN1-FALSEAluYk3SINE,Alu
chr1272096206AG2.06003E-07TMEM19+TRUEAluSz6SINE,Alu
chr11595078TC0.00714CDK11B,SLC35E2B-FALSEAluSgSINE,Alu
chr16257826TC0.00192RPL22-FALSE
chr1060047612AG0.00015CISD1+FALSE(A)nSINE,Alu
chr11534205GA1.69659E-11FNDC10-FALSE
chr3160154971TC0.00820TRIM59-FALSEAluJbSINE,Alu
chr7158679732GA0.00456WDR60+FALSE
chr194995411CA0.00849F3-FALSEAluSxSINE,Alu
chr1450792966AT0.00852.FALSEAluSxSINE,Alu
chr1117078729AG0.00983CD58-FALSE
chr794060363TG2.98576E-06COL1A2+FALSE
chr128661633AG0.00053MED18+TRUEAluSgSINE,Alu
chr133148196AG0.00756SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr146269493GC0.00233MAST2+FALSE
chr744917405CT0.00024PURB-FALSEAluSzSINE,Alu
chr593018903TA5.97109E-08FAM172A-FALSE(TCA)nSINE,Alu
chr42940477TC1.61307E-05NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr11655474GA0.00694CDK11B,CDK11A-FALSE
chr310192617AG2.94246E-06VHL+TRUEAluSx1SINE,Alu
chr4165996811TC6.80024E-05.FALSEAluSg4SINE,Alu
chr110521238TC0.00173DFFA-TRUEAluYSINE,Alu
chr185718132CA0.00738C1orf52-FALSE
chr128261662AG0.01000SMPDL3B+FALSE
chr1163394016TC0.00106ATL3-FALSE
chr10124913908CA0.00784BUB3+FALSE
chr47060959TC0.00832GRPEL1-FALSE
chr7129472357AG0.00287UBE2H-FALSE
chr1144604425CT0.00299NBPF20+FALSE
chr121611799AG0.00156LINC00942+FALSE
chr119542250TC0.00859LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chrX150573750AT0.00887VMA21+FALSE
chr110042937AG2.41028E-05NMNAT1+TRUEAluScSINE,Alu
chr146075664AG0.00267NASP+TRUEAluSx4SINE,Alu
chr144423703CT1.21014E-14IPO13+FALSE
chr2057603730AT0.00101.FALSE
chr3196079691TC0.00507.FALSEAluScSINE,Alu
chr2201774279TC9.55391E-05.FALSEAluSzSINE,Alu
chr1115313038GA0.00144SIKE1-FALSE
chr644417142AG0.00144CDC5L+TRUEFLAM_CSINE,Alu
chr137949806GA2.03247E-05ZC3H12A+FALSE
chr2018469054TC0.00522RBBP9-TRUEAluJrSINE,Alu
chr1540712737TC0.00525IVD+FALSE
chr371005566CT0.00209FOXP1-FALSE(T)nSINE,Alu
chr191863170GA0.00204KLF16-FALSE
chr1179044110AG0.00931FAM20B+TRUEAluSxSINE,Alu
chr3195461463AG0.00609.FALSEAluJbSINE,Alu
chr317201882CT0.00259TBC1D5-FALSE
chr170718276GT0.00836.FALSE
chr4169911126CA0.00122CBR4-FALSE
chr1113511341AG0.00283.FALSEAluYSINE,Alu
chr340353799GT0.00906EIF1B+FALSE
chr159124223GA0.00327MYSM1-FALSEMIR3SINE,Alu
chr1150783968TA0.00368ARNT-FALSE
chr1207942456AG0.00322CD46+TRUEAluSg4SINE,Alu
chr110042955AG0.00131NMNAT1+TRUEAluScSINE,Alu
chr145976112AG1.14998E-06MMACHC+TRUEAluJrSINE,Alu
chr76501828CA0.00110KDELR2-FALSE
chr1145273431AG0.00203NBPF20,NOTCH2NL+FALSE
chr5139680027AG0.00155PFDN1-FALSE
chr830536603TC9.61612E-06GSR-TRUEAluSpSINE,Alu
chr237330611TC0.00835.FALSEAluSq2SINE,Alu
chr1183105534TC0.00125LAMC1+FALSE
chr133086812TC0.00250.FALSEAluYSINE,Alu
chr152306075TC8.71211E-05NRDC-FALSE(TCA)nSINE,Alu
chr167874697TC0.00010SERBP1-TRUEAluSx3SINE,Alu
chr642856156AG0.00105RPL7L1+TRUEAluSzSINE,Alu
chr5121362874AG0.00607SRFBP1+TRUEFRAMSINE,Alu
chr127182751CA0.00122.FALSE
chr310302172GA0.00202TATDN2+FALSE
chr239009425AG0.00607.FALSEAluSx3SINE,Alu
chr1162557871GC0.00273TMEM179B,TMEM223+,-FALSE
chr1298942643AG3.59360E-06TMPO+TRUEAluScSINE,Alu
chr1153520954CT0.00910LOC101928034,S100A3+,-FALSE
chr286249930TC0.00054LOC90784-TRUEAluJrSINE,Alu
chr11663957CT0.00345SLC35E2-FALSE
chr312624763TC1.62214E-06MKRN2+FALSE
chr9131093971AG0.00033COQ4+TRUEAluJoSINE,Alu
chr744918732TC0.00039PURB-FALSEAluSgSINE,Alu
chr4159176109CA0.00042TMEM144+FALSEMIRSINE,Alu
chr312624321AG2.86985E-06MKRN2+FALSE
chr1206579798TC0.00476SRGAP2+FALSE
chr357613144TC0.00959DENND6A,PDE12+,-FALSEAluSzSINE,Alu
chr1565249466AG2.07949E-05ANKDD1A+TRUEAluSz6SINE,Alu
chr125893927AG0.00081LDLRAP1+FALSE
chr145976723TC0.00366MMACHC,PRDX1+,-FALSE
chr3120114128AC6.21214E-12FSTL1-FALSE
chr153289759AG0.00060ZYG11B+TRUEAluSzSINE,Alu
chr3150345451AG2.37481E-05SELT+TRUE
chr2172178680TC9.91686E-05METTL8-TRUEAluSx3SINE,Alu
chr366430374AT0.00275LRIG1-FALSE
chr2206981856TC0.00174.FALSEAluJbSINE,Alu
chr1109855150AC0.00062SORT1-FALSEA-richSINE,Alu
chr1214524496TC0.00114PTPN14-TRUEAluSgSINE,Alu
chr457326875AG1.03861E-05PAICS+TRUEAluSx1SINE,Alu
chr3184766301TC0.00025VPS8+FALSE
chr124293612GA0.00366.FALSE
chr1201488771AG0.00062.FALSEAluSq2SINE,Alu
chr1157044418GC0.00707.FALSE
chr1269237509AG1.55617E-05MDM2+TRUE
chr1110049203GC0.00209.FALSE
chr1743002237CA0.00141KIF18B-FALSE
chr133149495AG0.00652SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr1146650363TA0.00982PDIA3P1+FALSE
chr568850922GC0.00323OCLN+FALSEAluSx4SINE,Alu
chr1298943011AG1.18352E-07TMPO+TRUEAluSzSINE,Alu
chr1155403823AG0.00850ASH1L,POU5F1P4+,-FALSE
chr187379497AG0.00067SEP15-FALSE
chr146165408TC0.00106IPP-TRUEFRAMSINE,Alu
chr1657505635GT0.00974POLR2C+FALSE
chr489181431TC5.21801E-05PPM1K-TRUEAluSx1SINE,Alu
chr132697063TC0.00035EIF3I+FALSEAluSpSINE,Alu
chr16283264TC0.00073ICMT-TRUEAluSx3SINE,Alu
chr124296849TC0.00125.FALSE
chr1773886212TC0.00724TRIM65-TRUEFRAMSINE,Alu
chr1861565062CG0.00207SERPINB2+FALSE
chr237331627TC0.00030.FALSEAluJbSINE,Alu
chr110520669TC0.00963DFFA-FALSEAluSc8SINE,Alu
chr1745761110GT0.00816.FALSE
chr16651457GA0.00614KLHL21-FALSE
chr13729217TC0.00119CEP104-TRUEAluSx3SINE,Alu
chr1117945049GA0.00120MAN1A2+FALSE
chr119543457TC4.71011E-07LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr1321547676TC0.00403LATS2-FALSE
chr1168218573AG0.00202.FALSEAluSzSINE,Alu
chr274442548CT0.00035.FALSE
chr145244413TA0.00748.FALSE
chr1148556784GA0.00543.FALSE
chr2191184475AG0.00895HIBCH-FALSE
chr138411445GA0.00625INPP5B-FALSE
chr596366326GC0.00120.FALSE(TG)nSINE,Alu
chrX54587218AG0.00014GNL3L+TRUEAluSq2SINE,Alu
chr310193797AG0.00261VHL+TRUEAluSxSINE,Alu
chr9131093336TC0.00397COQ4+FALSEAluYSINE,Alu
chr11252441TC0.00086CPSF3L-TRUEAluJrSINE,Alu
chr340503557TC0.00487RPL14+FALSE
chr110519148TC0.00611.FALSEAluSx3SINE,Alu
chr119981886TG0.00082MINOS1-NBL1,NBL1+FALSE
chr1109818159GT0.00419CELSR2+FALSE
chr136068227TC0.00398PSMB2-TRUEAluScSINE,Alu
chr110521172TC0.00295DFFA-TRUEAluYSINE,Alu
chr3196670094GC5.91401E-08NCBP2-AS2+FALSE
chr348787052TC0.00226PRKAR2A-TRUEAluSx3SINE,Alu
chr154571380AG0.00332TCEANC2+TRUEAluScSINE,Alu
chr631324036TA0.00378.FALSE
chr126801731GT0.00325HMGN2+FALSE(T)nSINE,Alu
chr16582761TC0.00052NOL9-FALSEAluSgSINE,Alu
chr127204865TC0.00042.FALSEAluSxSINE,Alu
chr841798912TC0.00892KAT6A-FALSE
chr579923998TC0.00753DHFR-TRUEAluSpSINE,Alu
chr12123347005TA0.00268HIP1R+FALSE
chr339138082CT8.26379E-05WDR48+FALSE
chr126755209AG0.00745LIN28A+FALSEAluSx1SINE,Alu
chr146830447AC0.00168NSUN4+FALSELTR108a_MamSINE,Alu
chr29629298GC0.00590ADAM17-FALSE(TGT)nSINE,Alu
chr3196660052GA0.00200SENP5+FALSEAluSzSINE,Alu
chr1151027536GC0.00518CDC42SE1-FALSE
chr556177849CG0.00921MAP3K1+FALSE(CAA)nSINE,Alu
chr2025428616AG0.00817GINS1+FALSEAluJbSINE,Alu
chr1566933AG3.50078E-05.FALSE
chrX23721458TA0.00413.FALSEAluSc8SINE,Alu
chr1116237496TA0.00934VANGL1+FALSE
chr1160967856TC0.00116F11R-TRUEAluSpSINE,Alu
chr156961756AG0.00263PLPP3-FALSE
chr20279774AC0.00056ZCCHC3+FALSEL2bSINE,Alu
chr240336210CT0.00828SLC8A1-AS1+FALSE
chr1160231910AT0.00051DCAF8-FALSE
chr285824712CA0.00663RNF181+FALSE
chr1100550370TA0.00308SASS6-FALSE
chr3195242526CT3.14972E-05PPP1R2-FALSE
chr3122283287TC8.96368E-06DTX3L,PARP9+,-FALSE
chr310193743TC0.00456VHL+FALSEAluJrSINE,Alu
chr1144931330CT0.00066NBPF20,PDE4DIP+,-FALSE
chr247130527GA0.00462MCFD2-FALSE
chr1171751051AG0.00522METTL13+FALSE
chr2230629138CT0.00958TRIP12-FALSE
chr136770605CT0.00041THRAP3+FALSE(T)nSINE,Alu
chr129519712TC0.00017MECR-TRUEAluJbSINE,Alu
chr1298942695AG0.00204TMPO+TRUEAluScSINE,Alu
chr2128950515AG0.00208UGGT1+TRUEAluScSINE,Alu
chr12160988GA0.00137SKI+FALSE
chr337031951GA0.00154EPM2AIP1-FALSE(A)nSINE,Alu
chr1185069687CT0.00072RNF2+FALSE
chr1153507176CT0.00957S100A6-FALSE
chr3121154974TC0.00183POLQ-FALSE
chr110519936TC0.00072.FALSEAluJrSINE,Alu
chr128662105AG9.98367E-05MED18+TRUEAluSq2SINE,Alu
chr19160958TC3.87385E-05.FALSEAluJbSINE,Alu
chr9133579734AG0.00129EXOSC2+TRUEAluSx3SINE,Alu
chrX24095066GT0.00603EIF2S3+FALSE
chr11152309AT0.00030SDF4-FALSE
chr11534614TC5.67045E-11FNDC10-FALSE
chr2219134117CT0.00357AAMP-FALSE
chr1958371837AG0.00329ZNF587+TRUEAluSzSINE,Alu
chr3196557357GT0.00615PAK2+FALSE
chr133148706AG0.00050SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr1145282799GA0.00081NBPF20,NOTCH2NL+FALSE
chr5205565GA0.00593CCDC127-FALSE
chr264860431TG0.00213SERTAD2-FALSE
chr116893686GC0.00171NBPF1-FALSE
chr1200521412GA0.00292KIF14-FALSE
chr2161130868AC0.00297RBMS1-FALSE
chr1205686520AG0.00980NUCKS1-FALSE
chr5290174CT0.00083PDCD6+FALSE
chr119542310TC0.00581LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr5159492103TG0.00332TTC1+FALSE
chr1563363384CA0.00161TPM1+FALSE
chr119543249TC1.15194E-07LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr439550978TC0.00558UGDH-AS1,SMIM14+,-FALSEAluSzSINE,Alu
chr647594192CT0.00591CD2AP+FALSE
chr133148096AG0.00404SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr125168124GC0.00669CLIC4+FALSE
chr314985983AT6.81677E-14FGD5-AS1-FALSE
chr2218572729AG0.00228PEX26+TRUEAluYf1SINE,Alu
chr121101369TC0.00028HP1BP3-TRUEAluScSINE,Alu
chr8117784431TA0.00422UTP23+FALSEAluSz6SINE,Alu
chr5118811533GA0.00781HSD17B4+FALSE
chr114604AG0.00304WASH7P-FALSE
chr145244413TA0.00750.FALSE
chr2238678004AG0.00631LRRFIP1+FALSE
chr237329307TC0.00137.FALSEAluJr4SINE,Alu
chr4128757415AG0.00367.FALSEAluYSINE,Alu
chr2025428547AG7.92315E-05GINS1+TRUEAluJbSINE,Alu
chr1144931330CT0.00479NBPF20,PDE4DIP+,-FALSE
chr11653093AG0.00642CDK11B,CDK11A-FALSEL2SINE,Alu
chr1148004440CA0.00082NBPF8-FALSE
chr115988702TC0.00362.FALSE
chr5125962086AG0.00231PHAX+TRUEAluSzSINE,Alu
chr110521238TC0.00096DFFA-TRUEAluYSINE,Alu
chr1153907297CT3.91411E-05DENND4B-FALSE(CTG)nSINE,Alu
chr1149885583AG0.00030SV2A-FALSE
chr3188596752AG0.00203LPP+FALSE
chr1148251875TC0.00436NBPF8,NBPF14,NBPF9-FALSE
chr1172411768TC0.00416C1orf105,PIGC+,-FALSE
chr123834008AC0.00374E2F2-FALSEAluSzSINE,Alu
chr1247319706AT2.37466E-05ZNF124-FALSE
chr1145500920TA0.00286NBPF20,NBPF10,LIX1L+FALSE
chr310192596AG9.40892E-06VHL+TRUEAluSx1SINE,Alu
chr1028971536AT0.00815BAMBI+FALSE
chr488061645TA0.00049AFF1+FALSE(TATAT)nSINE,Alu
chr236704035CA0.00012CRIM1+FALSE
chr1207942535AG0.00102CD46+TRUEAluSg4SINE,Alu
chr193297609CT8.96972E-06RPL5+FALSE

Differential Expression Gene Analysis