Dataset Overview
RBPZNF768
Knock-MethodInhibition
RBP Familyzf-C2H2
Biosample NameU2OS
Tissue TypeBone
Biosample TypeCell line
# of Control4
# of Treat4
SpeciesHuman
Data SourceGEO
Profile IDGSE111881
PlatformGPL18460
Pubmed ID30476274

ZNF768 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of ZNF768
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of ZNF768


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr537290554TC0.00010.FALSEAluSzSINE,Alu
chr11337737GC2.51903E-05MRPL20-FALSE
chr16282400TC0.00601ICMT-TRUEAluSzSINE,Alu
chr120976032TC9.95086E-05PINK1,PINK1-AS+,-FALSEAluSzSINE,Alu
chr1184675814GA0.00048EDEM3-FALSE
chr417802783TC6.83941E-07DCAF16-TRUEAluSzSINE,Alu
chr5125961509AG0.00141PHAX+TRUEAluSz6SINE,Alu
chr127204515TC0.00337.FALSEAluSg7SINE,Alu
chr1913883923AG0.00493MRI1+TRUEAluSzSINE,Alu
chr683921257GT0.00876ME1-FALSE
chr1913884096AG0.00049MRI1+TRUEAluSzSINE,Alu
chr1117531621AG0.00577PTGFRN+FALSE
chr16283260TC0.00054ICMT-TRUEAluSx3SINE,Alu
chr1193054574GT0.00511TROVE2+FALSE(ATTTT)nSINE,Alu
chr237429627AG0.00330CEBPZOS,CEBPZ+,-FALSEAluSzSINE,Alu
chr830536146TC1.15312E-06GSR-TRUEAluJrSINE,Alu
chr315113847TC0.00026RBSN-TRUEAluSz6SINE,Alu
chr270131584GA0.00366SNRNP27+FALSE
chr147685593AC0.00891TAL1-FALSE(CCACCC)nSINE,Alu
chr1205737665GT0.00078RAB29-FALSEAluSq2SINE,Alu
chr145975574AG0.00299MMACHC+TRUEAluSx4SINE,Alu
chr120976174TC0.00103PINK1,PINK1-AS+,-FALSEAluSzSINE,Alu
chr1229795330TC0.00334URB2+FALSE
chr488059664TG0.00178AFF1+FALSE(GT)nSINE,Alu
chr438945689CT1.01800E-05FAM114A1+FALSEAluScSINE,Alu
chr11251841TC0.00222CPSF3L-TRUEAluSq2SINE,Alu
chr7128143797AG4.50405E-06.FALSEAluSq2SINE,Alu
chr1151862656TC0.00933THEM4-TRUEAluSpSINE,Alu
chr133148367CG0.00020SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr116909208CG0.00482NBPF1-FALSE
chr5176863519GC0.00567GRK6+FALSE
chr145110404CT0.00230RNF220+FALSE
chr1110566328AT0.00515AHCYL1+FALSE
chr314986452TC0.00815FGD5-AS1-TRUEAluSq2SINE,Alu
chr153289790CT0.00281ZYG11B+FALSEAluSzSINE,Alu
chr744841489AG0.00015PPIA+TRUEAluJrSINE,Alu
chr140537944CA2.58277E-05CAP1+FALSE
chr16282420TC0.00133ICMT-TRUEAluSzSINE,Alu
chr110517306TC0.00102.FALSEAluJrSINE,Alu
chr1114226255GA0.00381MAGI3+FALSE
chr1269159400GA0.00173SLC35E3+FALSE(AT)nSINE,Alu
chr2218696215AG0.00915TNS1-FALSE
chr1198867678GT0.00545MIR181A1HG-FALSE
chr274645427AG0.00011C2orf81-FALSE
chr388199298TC0.00048C3orf38+FALSE
chr1110136846TA0.00639GNAI3+FALSE
chr133149495AG0.00421SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr1153587308CT0.00077S100A14-FALSE
chr1541590943AG0.00561OIP5-AS1+TRUEAluSx1SINE,Alu
chr1182686151TC0.00404RAB30-FALSE
chr269688917TC0.00254AAK1-TRUEAluSq2SINE,Alu
chr1900719TA0.00436KLHL17+FALSE(TTTA)nSINE,Alu
chr116928622CA0.00011NBPF1-FALSE
chr1251324122AG0.00226METTL7A+TRUEAluSq2SINE,Alu
chr133086754TC0.00065.FALSEAluYSINE,Alu
chr2110373919GA0.00240SOWAHC+FALSE
chr1157963370CG0.00445KIRREL+FALSE
chr1168218573AG0.00202.FALSEAluSzSINE,Alu
chrX54587254AG0.00019GNL3L+TRUEAluSq2SINE,Alu
chr10100177984CT6.55965E-05HPS1-FALSE
chr119543456TC0.00386LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr629910586GA1.69263E-05.FALSE
chr2234386134AG0.00196USP40-FALSE
chr119586455AG0.00296MRTO4+TRUEAluSzSINE,Alu
chr178187733GA0.00388USP33-FALSE
chr357612314TC0.00529DENND6A,PDE12+,-FALSEAluSpSINE,Alu
chr5125961667AG1.34346E-05PHAX+TRUEAluSz6SINE,Alu
chr344791536TC4.11776E-05KIAA1143-TRUEAluJrSINE,Alu
chr841401571TA0.00240LOC102723729,GINS4+,-FALSE
chr2176042871AT0.00204ATP5G3-FALSE
chr182804129GA0.00157SMCHD1+FALSE
chr314986110TC0.00632FGD5-AS1-TRUEFLAM_CSINE,Alu
chr3194998813AG0.00572ACAP2-FALSEAluSx1SINE,Alu
chr8128944725GC0.00491PVT1+FALSE
chr116912099GC0.00928NBPF1-FALSE
chr227001973CT0.00327SLC35F6+FALSEAluSxSINE,Alu
chr1168218522AG0.00073.FALSEAluSzSINE,Alu
chr1146033660CA0.00091NBPF20,NBPF10,NBPF25P,NBPF11+,-FALSE
chr168940887TG0.00293DEPDC1-FALSEMIRSINE,Alu
chr495588274GA0.00095PDLIM5+FALSE
chr1145512151CA0.00723NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr136068325TC0.00746PSMB2-TRUEAluScSINE,Alu
chr1113672691AG0.00515.FALSEAluJbSINE,Alu
chr1615794312CT0.00796NDE1+FALSEAluSzSINE,Alu
chr127204436TC1.54117E-06.FALSEAluSg7SINE,Alu
chr345721922AG0.00181LIMD1,LIMD1-AS1+,-FALSEAluJbSINE,Alu
chr146075664AG0.00537NASP+TRUEAluSx4SINE,Alu
chr274333235CT0.00022TET3+FALSE
chr1225682175CT0.00610ENAH-FALSE
chr1145693061AG0.00158NBPF20,NBPF10+TRUEAluSz6SINE,Alu
chr696054540GT0.00358MANEA+FALSE
chr285132777TC1.13350E-06TMSB10+FALSE
chr174672474GA0.00292FPGT-TNNI3K,FPGT+FALSEX12_DNASINE,Alu
chr275882576TC0.00328MRPL19+FALSE
chr576371820AG0.00162.FALSE
chr1160967833TC6.62581E-12F11R-TRUEAluSpSINE,Alu
chr2178129405CT0.00295NFE2L2-FALSE(CGG)nSINE,Alu
chr1757279281AG0.00055PRR11+TRUEAluSq2SINE,Alu
chr2128951766AG0.00050UGGT1+TRUEAluSpSINE,Alu
chr333877626GA2.14228E-08PDCD6IP+FALSE
chr1109192040TC6.39517E-05HENMT1-TRUEAluJrSINE,Alu
chr110518037TC0.00017.FALSEAluJrSINE,Alu
chr127175047AG0.00634C1S+FALSE
chr2106510202CT0.00854NCK2+FALSE
chr133145958GT0.00080SYNC,RBBP4+,-FALSE(T)nSINE,Alu
chr425253995CT9.95051E-10PI4K2B+FALSE
chr1109475635TC0.00458GPSM2,CLCC1+,-FALSEAluJoSINE,Alu
chr540835321AT0.00526RPL37-FALSE
chr899053985TG4.76792E-05RPL30-FALSE
chr12109887765TG0.00091KCTD10-FALSE
chr467846CA0.00573ZNF718,ZNF595+FALSEAluYk3SINE,Alu
chr12115914GT0.00970PRKCZ,FAAP20+,-FALSE
chr1144813815AG2.28281E-05NBPF20,NBPF9+FALSE
chr47060935GC0.00543GRPEL1-FALSETigger4aSINE,Alu
chr285776648TC0.00765GGCX-TRUEAluSz6SINE,Alu
chr19160996TC0.00023.FALSEAluJbSINE,Alu
chr120224152GA0.00581OTUD3+FALSE
chr5178508569CT0.00571ZNF354C+FALSE
chr128825418AG0.00961PHACTR4+TRUEAluSgSINE,Alu
chr1114443574AG0.00162AP4B1-AS1,AP4B1+,-FALSEAluSpSINE,Alu
chr3194349178CT0.00881TMEM44-FALSE
chr116889864CA0.00598NBPF1-FALSE
chr1745761108GT0.00127.FALSE
chr1241796948TC0.00082OPN3,CHML-FALSE
chr11252221TC0.00728CPSF3L-TRUEAluSxSINE,Alu
chr18412652AC0.00929RERE-FALSE
chr1953914418AG0.00891ZNF765+TRUEAluSxSINE,Alu
chr144088547CA0.00927PTPRF+FALSEA-richSINE,Alu
chr1541597574AG2.24597E-05.FALSEAluSz6SINE,Alu
chr128826118AG0.00039PHACTR4+TRUEAluJbSINE,Alu
chr42940265TC4.71601E-06NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr1144598755GA0.00743NBPF20+FALSE
chr238522141GT0.00147ATL2-FALSE
chr246808168CT0.00377RHOQ+FALSE
chr1144931330CT0.00194NBPF20,PDE4DIP+,-FALSE
chr5178986978CG0.00341RUFY1+FALSE
chr1145311900CT0.00286NBPF20,NBPF10+FALSE
chr1144930596CA0.00013NBPF20,PDE4DIP+,-FALSE
chr1288454641AT0.00753CEP290-FALSE
chr2206983087TC0.00364.FALSEAluJbSINE,Alu
chr299216531AG0.00049COA5-FALSEMLT1KSINE,Alu
chr1230979247GA0.00137C1orf198-FALSE
chr3156258273TC0.00927SSR3-TRUEAluYk3SINE,Alu
chr642045563AG4.21139E-05TAF8+TRUEAluSzSINE,Alu
chr268402154AT0.00991PNO1+FALSE
chr1145313405CT0.00322NBPF20,NBPF10+FALSE
chr2232319593AC0.00348NCL-FALSEA-richSINE,Alu
chr123150853CG0.00158.FALSE(CCTCCCTG)nSINE,Alu
chr1113212976CT0.00332CAPZA1+FALSE
chr250148477CT0.00741NRXN1-FALSE
chr131905886CA0.00273SERINC2+FALSE
chr5174956494TA2.51545E-05SFXN1+FALSE
chr146164493TC0.00977IPP-TRUEAluJbSINE,Alu
chr1143135057GA0.00403LOC102723769-FALSE
chr349453834CT0.00518TCTA+FALSE
chr286249961TC0.00368LOC90784-TRUEAluJrSINE,Alu
chr1571124666CA4.50846E-10LARP6-FALSE
chr116933110TC0.00821NBPF1-FALSEL1MC2SINE,Alu
chr344772983CT0.00795ZNF501+FALSE
chr1145116142AT0.00570NBPF20,SEC22B+FALSE
chr116933628AG0.00430NBPF1-FALSEGA-richSINE,Alu
chr110043363AG0.00509NMNAT1+TRUEAluSx3SINE,Alu
chr142881767GC0.00437RIMKLA+FALSE
chr540715440AC0.00646TTC33-FALSE
chr2174090636TA0.00043ZAK,MLK7-AS1+,-FALSE
chr3195412715TC0.00837SDHAP2+FALSE
chr11662754TC0.00107SLC35E2-TRUEAluYSINE,Alu
chr8104312341AG0.00692FZD6+FALSE
chr17828190AC0.00049CAMTA1+FALSE(A)nSINE,Alu
chr237327669TC0.00566.FALSE
chr119586294AG0.00048MRTO4+FALSE
chr2174090635TA0.00138ZAK,MLK7-AS1+,-FALSE
chr1231154918GT0.00022FAM89A-FALSE(T)nSINE,Alu
chr154691921GA0.00010SSBP3-FALSE
chr1243289448GA0.00036CEP170-FALSE
chr167874697TC0.00190SERBP1-TRUEAluSx3SINE,Alu
chr2100899665GA0.00758LONRF2-FALSE
chr110518733TC0.00541.FALSEAluSx1SINE,Alu
chr1590820073AG0.00012.FALSEAluYSINE,Alu
chr110517672TC0.00070.FALSEAluSx1SINE,Alu
chr237331745TC0.00097.FALSEAluJbSINE,Alu
chr11594498CT0.00024CDK11B,SLC35E2B-FALSE
chr128564612CA0.00714ATPIF1+FALSE
chr2161130868AC0.00297RBMS1-FALSE
chr199673276CA0.00085.FALSETigger1SINE,Alu
chr2158636910GA0.00160ACVR1-FALSE
chr299812447AG0.00525MRPL30+TRUEAluSxSINE,Alu
chr146830110AG0.00283NSUN4+TRUEAluSx1SINE,Alu
chr232447868AG0.00663SLC30A6+FALSE
chr2101622881CA1.48865E-05RPL31+FALSE
chr2218572730AG6.64824E-05PEX26+TRUEAluYf1SINE,Alu
chr286251114TC0.00150.FALSEAluSxSINE,Alu
chr125570692CT0.00095RSRP1-FALSE
chr1115299504GT0.00067CSDE1-FALSE
chr1165544575TC0.00200AP5B1-TRUEAluJbSINE,Alu
chr230863651AT0.00366LCLAT1+FALSE
chr310193743TC0.00456VHL+FALSEAluJrSINE,Alu
chr4187509420GA0.00121FAT1-FALSE
chr5118175329TC2.47285E-05DTWD2-TRUEAluJrSINE,Alu
chr237431521AG0.00783CEBPZOS,CEBPZ+,-FALSEAluScSINE,Alu
chr42940135TC5.42423E-07NOP14-AS1,NOP14+,-FALSEAluSpSINE,Alu
chr136067752TC0.00402PSMB2-TRUEAluSzSINE,Alu
chr1757279284AG0.00149PRR11+TRUEAluSq2SINE,Alu
chr1773940077TC0.00146ACOX1-TRUEAluJbSINE,Alu
chr115899345TC0.00300AGMAT-TRUEAluSx3SINE,Alu
chr2102508655GT0.00817MAP4K4+FALSE
chr140539201AG0.00028PPT1-FALSE
chr1179070187GA0.00556ABL2-FALSE
chr145504720GC0.00759ZSWIM5-FALSE
chr122419433TG0.00156CDC42+FALSE
chr1179829096TC4.38746E-06TOR1AIP2-TRUEAluJrSINE,Alu
chr310193797AG0.00261VHL+TRUEAluSxSINE,Alu
chr2224621887TC0.00373AP1S3-FALSEAluScSINE,Alu
chr310192717AG3.16601E-05VHL+TRUEAluSx1SINE,Alu
chr1461112736TG0.00418SIX1-FALSE(T)nSINE,Alu
chr1450053348GA0.00067.FALSE7SLRNASINE,Alu
chr7128143289AG0.00082.FALSEAluSc8SINE,Alu
chr124798498CT0.00131NIPAL3+FALSE
chr1118069696TC0.00922.FALSE
chr1120612163CA0.00812NOTCH2-FALSE
chr128835201CT0.00371SNHG3,RCC1,SNORA73B+FALSEU17SINE,Alu
chr1249745500AG0.00265DNAJC22+TRUEAluSx3SINE,Alu
chr1109865630CT0.00647SORT1-FALSE
chr140361783GC0.00023MYCL-FALSE
chr2025427756AG0.00396GINS1+TRUEAluSzSINE,Alu
chr456298300GA7.51019E-06CLOCK-FALSE
chr16282400TC0.00809ICMT-TRUEAluSzSINE,Alu
chr1145827050GC0.00045SLC35C1+FALSE
chr642856029AG0.00099RPL7L1+TRUEAluSzSINE,Alu
chr399463810GT0.00599MIR548G,COL8A1+,-FALSE
chr5157184013AG0.00631LSM11+TRUEAluYSINE,Alu
chr116842064AC0.00081.FALSEMER41ESINE,Alu
chr119543309TC0.00769LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr2232028396AG0.00701PSMD1+FALSE
chr160340527GA0.00027HOOK1+FALSE
chr398299365TG3.92075E-11CPOX-FALSE
chr7102016322AG0.00223LOC100289561,LOC100630923+FALSE
chr1911256697TC0.00039SPC24-TRUEAluJr4SINE,Alu
chr457801194AT0.00834REST+FALSE
chr127108245TC0.00265ARID1A+FALSE
chr631236900GA0.00167.FALSE
chr823294732CT0.00415ENTPD4-FALSE
chr116912014AC0.00029NBPF1-FALSE
chr324019990AG0.00308NR1D2+FALSE
chr119543352TC0.00715LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr185484276CT0.00168MCOLN3-FALSE
chr1109818161CT6.45247E-05CELSR2+FALSE
chr4184238324GA0.00870WWC2+FALSE
chr1114438951AG0.00017AP4B1-AS1,AP4B1+,-FALSE
chr12125269489CT0.00817SCARB1-FALSE
chr2160084473AC0.00101TANC1+FALSE
chr11421186CT0.00834ATAD3B+FALSE
chr1180854783TC0.00292XPR1+FALSE
chr642854611AG0.00541RPL7L1+TRUEAluScSINE,Alu
chr42940347TC1.36349E-05NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr2151326173AC0.00143RND3-FALSE
chr1218617066AT0.00211TGFB2-OT1,TGFB2+FALSE
chr310168785TC0.00198BRK1+FALSE
chr811701485TC0.00027CTSB-TRUEAluSx1SINE,Alu
chr1131452750AG0.00326DNAJC24+TRUEAluSx1SINE,Alu
chr136067752TC5.48772E-07PSMB2-TRUEAluSzSINE,Alu
chr345721836AG0.00310LIMD1,LIMD1-AS1+,-FALSEAluJbSINE,Alu
chr356654600CG2.66528E-07CCDC66,FAM208A+,-FALSE
chr1142660072TG0.00773.FALSE
chr1145369706TC0.00186NBPF20,NBPF10+FALSEL1MC4SINE,Alu
chr152817432TC0.00518CC2D1B-TRUEAluSg4SINE,Alu
chr1214527252GA0.00830PTPN14-FALSEMADE2SINE,Alu
chr3172115476AG0.00892FNDC3B+FALSE(A)nSINE,Alu
chr11668168GT1.67311E-07SLC35E2-FALSEAluSzSINE,Alu
chr132833541TC0.00903BSDC1-TRUE
chr34403537CT0.00055SUMF1-FALSEMIR3SINE,Alu
chr986553587GA0.00556C9orf64-FALSE
chr248605828TA0.00650FOXN2+FALSE(T)nSINE,Alu
chr439549703TC0.00150UGDH-AS1,SMIM14+,-FALSEAluSpSINE,Alu

Differential Expression Gene Analysis