Gorilla_gorillaFamily: DEAD Number of Genes: 84
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
-
-
TDRD9
DDX28
DHX29
MTREX
SKIV2L
DDX4
ERCC6L2
-
DHX33
ASCC3
DDX3X
DICER1
DHX30
DDX21
SNRNP200
DHX37
DDX39A
DHX58
EIF4A2
DDX47
DDX39B
DDX24
DDX42
BLM
DHX57
DDX17
DDX31
FANCM
HELQ
DDX19A
RECQL5
DDX50
DDX51
DDX54
RAD54L
RECQL
POLQ
-
DDX56
DDX1
SMARCA5
DDX60
-
-
EIF4A3
DHX38
DHX9
DDX46
RECQL4
YTHDC2
DDX41
DDX59
DDX60L
DDX25
DDX23
DDX5
-
DDX20
IFIH1
DDX43
DDX58
DDX6
DHX15
WRN
DHX16
-
-
-
-
EIF4A1
-
-
DDX55
-
-
DDX52
DDX18
DHX36
DDX19B
-
-
DDX49
-
-
HFM1
-
-
-
-
-
-
-
-
-
-
-
-

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.