Mus_musculus_c3hhejFamily: GidB Number of Genes: 1
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
Gstcd
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Introduction

Pfam

This is a family of bacterial glucose inhibited division proteins these are probably involved in the regulation of cell devision [1]. GidB has been shown to be a methyltransferase G specific to the rRNA small subunit [2, 3]. Previously identified as a glucose-inhibited division protein B that appears to be present and in a single copy in all complete eubacterial genomes so far sequenced. GidB specifically methylates the N7 position of a guanosine in 16S rRNA [4].

InterPro

This entry represents a rRNA small subunit methyltransferase G. Previously identified as a glucose-inhibited division protein B that appears to be present and in a single copy in all complete eubacterial genomes so far sequenced. Specifically methylates the N7 position of a guanosine in 16S rRNA [PUBMED:12001236, PUBMED:17238915, PUBMED:17573471].

Reference

  1. Gal-Mor O, Borovok I, Av-Gay Y, Cohen G, Aharonowitz Y; , Gene 1998;217:83-90.: Gene organization in the trxA/B-oriC region of the Streptomyces coelicolor chromosome and comparison with other eubacteria. PUBMED:9795152 EPMC:9795152 .

  2. Romanowski MJ, Bonanno JB, Burley SK;, Proteins. 2002;47:563-567.: Crystal structure of the Escherichia coli glucose-inhibited division protein B (GidB) reveals a methyltransferase fold. PUBMED:12001236 EPMC:12001236 .

  3. Okamoto S, Tamaru A, Nakajima C, Nishimura K, Tanaka Y, Tokuyama S, Suzuki Y, Ochi K;, Mol Microbiol. 2007;63:1096-1106.: Loss of a conserved 7-methylguanosine modification in 16S rRNA confers low-level streptomycin resistance in bacteria. PUBMED:17238915 EPMC:17238915 .

  4. Nishimura K, Johansen SK, Inaoka T, Hosaka T, Tokuyama S, Tahara Y, Okamoto S, Kawamura F, Douthwaite S, Ochi K;, J Bacteriol. 2007;189:6068-6073.: Identification of the RsmG methyltransferase target as 16S rRNA nucleotide G527 and characterization of Bacillus subtilis rsmG mutants. PUBMED:17573471 EPMC:17573471.