Drosophila_melanogasterFamily: Ints3 Number of Genes: 1
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
IntS3

Introduction

Pfam

The Integrator complex is involved in small nuclear RNA (snRNA) U1 and U2 transcription, and in their 3'-box- dependent processing. This complex associates with the C- terminal domain of RNA polymerase II largest subunit and is recruited to the U1 and U2 snRNAs genes [1]. This entry represents subunit 3 of this complex.

InterPro

The Integrator complex is involved in small nuclear RNA (snRNA) U1 and U2 transcription, and in their 3'-box-dependent processing. This complex associates with the C-terminal domain of RNA polymerase II largest subunit and is recruited to the U1 and U2 snRNAs genes [PUBMED:16239144].

Reference

  1. Baillat D, Hakimi MA, Naar AM, Shilatifard A, Cooch N, Shiekhattar R;, Cell. 2005;123:265-276.: Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II. PUBMED:16239144 EPMC:16239144.