EuRBPDB

Drosophila_melanogasterFamily: Ints3 Number of Genes: 1

Ensembl ID	Symbol	Entrez ID	RBD	RBPome	PRI	Expresion	Pathway	Phenotype	Paralog	Ortholog	GO
FBgn0262117	IntS3	3355010

Introduction

Pfam

The Integrator complex is involved in small nuclear RNA (snRNA) U1 and U2 transcription, and in their 3'-box- dependent processing. This complex associates with the C- terminal domain of RNA polymerase II largest subunit and is recruited to the U1 and U2 snRNAs genes [1]. This entry represents subunit 3 of this complex.

InterPro

The Integrator complex is involved in small nuclear RNA (snRNA) U1 and U2 transcription, and in their 3'-box-dependent processing. This complex associates with the C-terminal domain of RNA polymerase II largest subunit and is recruited to the U1 and U2 snRNAs genes [PUBMED:16239144].

Reference

Baillat D, Hakimi MA, Naar AM, Shilatifard A, Cooch N, Shiekhattar R;, Cell. 2005;123:265-276.: Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II. PUBMED:16239144 EPMC:16239144.