Chlorocebus_sabaeusFamily: MA3 Number of Genes: 6
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
EIF4G3
EIF4G2
PDCD4
-
CWC22
EIF4G1

Introduction

Pfam

Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain repeats and/or regions similar to MIF4G domains [1].

InterPro

This entry represents the MI domain (after MA-3 and eIF4G), it is a protein-protein interaction module of ~130 amino acids [PUBMED:10958635, PUBMED:10973054, PUBMED:15082783]. It appears in several translation factors and is found in:

Reference

  1. Ponting CP; , Trends Biochem Sci 2000;25:423-426.: Novel eIF4G domain homologues linking mRNA translation with nonsense-mediated mRNA decay. PUBMED:10973054 EPMC:10973054.