Macaca_mulattaFamily: MMR_HSR1 Number of Genes: 116
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
RAB22A
ARFRP1
NUGGC
-
-
SEPT9
IFI44L
RABL3
RAB7A
ERAL1
RAB44
EHD3
EHD4
EHD1
MFN1
RAB15
SAR1B
SEPT2
MTG1
SAR1A
SEPT7
RAB5A
OLA1
RAB34
ARL5B
RAB30
RAB11A
GNL3L
GNL2
-
-
-
ARL8B
SRPRB
RAB6B
GUF1
DNAJC27
RAB11B
-
SEPT8
RERG
LSG1
GTPBP4
ARL4A
GIMAP4
ARL4C
ARL11
GNL3
MTG2
DNM1L
RAB41
NKIRAS2
-
RAB5C
GTPBP8
RAB2B
RAB39B
SEPT3
RAB36
KRAS
GIMAP2
RAB2A
-
RRAGB
GIMAP7
-
SEPT6
-
-
RAB23
RRAGA
-
EEFSEC
EIF5B
DRG1
ARL10
GPN1
SEPT11
GNL1
RAB33B
RAB9B
ARL4D
DRG2
HRAS
RAB1A
SEPT1
RAB25
NOA1
RAB9A
GIMAP8
EEF2
RABL2B
GTPBP3
MFN2
CRACR2A
GTPBP10
MTIF2
-
ARL8A
ARL14
ARL1
RAB5B
-
-
RASL11B
ARL6
EHD2
ARL2
-
-
-
-
-
-
-
IRGC
SEPT14
ARF5
RAB35
-
-
RAB18
ARL3
GIMD1
-
GIMAP6
RAB14
NRAS

Introduction

Pfam

The full-length GTPase protein is required for the complete activity of the protein of interacting with the 50S ribosome and binding of both adenine and guanine nucleotides, with a preference for guanine nucleotide.

InterPro

Several proteins have recently been shown to contain the 5 structural motifs characteristic of GTP-binding proteins [PUBMED:1449490]. These include murine DRG protein; GTP1 protein from Schizosaccharomyces pombe; OBG protein from Bacillus subtilis [PUBMED:12429099]; ferrous iron transport protein B [PUBMED:20123128] and several others.

Reference

  1. Vernet C, Ribouchon MT, Chimini GPontarotti P; , Mamm Genome 1994;5:100-105.: Structure and evolution of a member of a new subfamily of GTP-binding proteins mapping to the human MHC class I region. PUBMED:8180467 EPMC:8180467 .

  2. Bassler J, Kallas M, Hurt E;, J Biol Chem. 2006;281:24737-24744.: The NUG1 GTPase reveals and N-terminal RNA-binding domain that is essential for association with 60 S pre-ribosomal particles. PUBMED:16803892 EPMC:16803892 .

  3. Jain N, Dhimole N, Khan AR, De D, Tomar SK, Sajish M, Dutta D, Parrack P, Prakash B;, Biochem Biophys Res Commun. 2009;379:201-205.: E. coli HflX interacts with 50S ribosomal subunits in presence of nucleotides. PUBMED:19109926 EPMC:19109926 .

  4. Dutta D, Bandyopadhyay K, Datta AB, Sardesai AA, Parrack P;, J Bacteriol. 2009;191:2307-2314.: Properties of HflX, an enigmatic protein from Escherichia coli. PUBMED:19181811 EPMC:19181811 .

  5. Shields MJ, Fischer JJ, Wieden HJ;, Biochemistry. 2009;48:10793-10802.: Toward understanding the function of the universally conserved GTPase HflX from Escherichia coli: a kinetic approach. PUBMED:19824612 EPMC:19824612.