Mustela_putorius_furoFamily: MMR_HSR1 Number of Genes: 101
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
DRG2
SEPT2
RAB2B
GTPBP8
RAB11A
ARL5A
-
-
RAB5B
NUGGC
ARF1
-
-
GTPBP6
-
-
RAB23
-
ARL6
RAB36
LSG1
-
SAR1A
EHD2
EEF2
RAB31
NOA1
RAB25
GUF1
EHD3
-
RASL11B
RAB1A
IRGC
-
ARF5
RAB11B
-
-
RAB14
MTG2
SEPT7
RAB30
SEPT11
-
RABL3
ARFRP1
GIMD1
CRACR2A
RASL11A
EHD4
SRPRB
RAB6A
SAR1B
KRAS
-
MTIF2
SEPT8
RAB5C
NKIRAS2
RAB18
RAB1B
GNL3L
RERG
ARL1
GNL1
ARL5B
EIF5B
TBC1D10B
-
EHD1
ARL10
DRG1
RASEF
RAB5A
SEPT9
OLA1
DNAJC27
ERAL1
-
-
RAB34
GNL2
-
SEPT12
SRL
-
-
GTPBP3
RAB33B
RAB39B
GTPBP4
SEPT14
-
SEPT3
-
MFN2
GNL3
ARL3
ARF4
MFN1
RAB7A
EEFSEC
GTPBP10
ARL11
ARL14
RAB9A
ARL4D
RRAGA
RAB9B
ARL4C
ARL4A

Introduction

Pfam

The full-length GTPase protein is required for the complete activity of the protein of interacting with the 50S ribosome and binding of both adenine and guanine nucleotides, with a preference for guanine nucleotide.

InterPro

Several proteins have recently been shown to contain the 5 structural motifs characteristic of GTP-binding proteins [PUBMED:1449490]. These include murine DRG protein; GTP1 protein from Schizosaccharomyces pombe; OBG protein from Bacillus subtilis [PUBMED:12429099]; ferrous iron transport protein B [PUBMED:20123128] and several others.

Reference

  1. Vernet C, Ribouchon MT, Chimini GPontarotti P; , Mamm Genome 1994;5:100-105.: Structure and evolution of a member of a new subfamily of GTP-binding proteins mapping to the human MHC class I region. PUBMED:8180467 EPMC:8180467 .

  2. Bassler J, Kallas M, Hurt E;, J Biol Chem. 2006;281:24737-24744.: The NUG1 GTPase reveals and N-terminal RNA-binding domain that is essential for association with 60 S pre-ribosomal particles. PUBMED:16803892 EPMC:16803892 .

  3. Jain N, Dhimole N, Khan AR, De D, Tomar SK, Sajish M, Dutta D, Parrack P, Prakash B;, Biochem Biophys Res Commun. 2009;379:201-205.: E. coli HflX interacts with 50S ribosomal subunits in presence of nucleotides. PUBMED:19109926 EPMC:19109926 .

  4. Dutta D, Bandyopadhyay K, Datta AB, Sardesai AA, Parrack P;, J Bacteriol. 2009;191:2307-2314.: Properties of HflX, an enigmatic protein from Escherichia coli. PUBMED:19181811 EPMC:19181811 .

  5. Shields MJ, Fischer JJ, Wieden HJ;, Biochemistry. 2009;48:10793-10802.: Toward understanding the function of the universally conserved GTPase HflX from Escherichia coli: a kinetic approach. PUBMED:19824612 EPMC:19824612.