Microtus_ochrogasterFamily: MRP Number of Genes: 1
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
Sun1

Introduction

Pfam

MRP1 and MRP2 are mitochondrial RNA binding proteins that form a heteromeric complex. The MRP1/MRP2 heterotetrameric complex binds to guide RNAs and stabilises them in an unfolded conformation suitable for RNA-RNA hybridisation. Each MRP subunit adopts a 'whirly' transcription factor fold [1].

InterPro

No InterPro abstract

Reference

  1. Schumacher MA, Karamooz E, Zikova A, Trantirek L, Lukes J; , Cell. 2006;126:701-711.: Crystal structures of T. brucei MRP1/MRP2 guide-RNA binding complex reveal RNA matchmaking mechanism. PUBMED:16923390 EPMC:16923390.