| Ensembl ID | Symbol | Entrez ID | RBD | RBPome | PRI | Expresion | Pathway | Phenotype | Paralog | Ortholog | GO |
|---|---|---|---|---|---|---|---|---|---|---|---|
This family of proteins the superfamily of PHD-finger proteins. At least one example, from mouse, may act as a chromatin-associated [1]. The S. pombe ini1 gene is essential, required for splicing [2]. It is localised in the nucleus, but not detected in the nucleolus and can be complemented by human ini1 [2].
Phf5 is a member of a novel murine multigene family that is highly conserved during evolution and belongs to the superfamily of PHD-finger proteins. At least one example, from Mus musculus (mouse), may act as a chromatin-associated protein [PUBMED:14762117]. The Schizosaccharomyces pombe (fission yeast) ini1 gene is essential, required for splicing [PUBMED:12054543]. It is localised in the nucleus, but not detected in the nucleolus and can be complemented by human ini1 [PUBMED:12054543]. The proteins of this family contain five CXXC motifs.
Trappe R, Ahmed M, Glaser B, Vogel C, Tascou S, Burfeind P, Engel W; , Biochem Biophys Res Commun 2002;293:816-826.: Identification and characterization of a novel murine multigene family containing a PHD-finger-like motif. PUBMED:12054543 EPMC:12054543 .
Oltra E, Verde F, Werner R, D'Urso G; , J Cell Sci 2004;117:967-974.: A novel RING-finger-like protein Ini1 is essential for cell cycle progression in fission yeast. PUBMED:14762117 EPMC:14762117.
