Cercocebus_atysFamily: RAP Number of Genes: 5
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
FASTKD3
TBRG4
FASTKD1
FASTKD2
FASTK

Introduction

Pfam

This domain is found in various eukaryotic species, where it is found in proteins that are important in various parasite-host cell interactions. It is thought to be an RNA-binding domain [1]. The domain is involved in plant defence in response to bacterial infection [2,3].

InterPro

The ~60-residue RAP (an acronym for RNA-binding domain abundant in Apicomplexans) domain is found in various proteins in eukaryotes. It is particularly abundant in apicomplexans and might mediate a range of cellular functions through its potential interactions with RNA [PUBMED:15501674].

Reference

  1. Lee I, Hong W; , Trends Biochem Sci 2004;29:567-570.: RAP--a putative RNA-binding domain. PUBMED:15501674 EPMC:15501674 .

  2. Katiyar-Agarwal S, Gao S, Vivian-Smith A, Jin H;, Genes Dev. 2007;21:3123-3134.: A novel class of bacteria-induced small RNAs in Arabidopsis. PUBMED:18003861 EPMC:18003861 .

  3. Katiyar-Agarwal S, Jin H;, Annu Rev Phytopathol. 2010;48:225-246.: Role of small RNAs in host-microbe interactions. PUBMED:20687832 EPMC:20687832.