Drosophila_melanogasterFamily: RAP Number of Genes: 1
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO



This domain is found in various eukaryotic species, where it is found in proteins that are important in various parasite-host cell interactions. It is thought to be an RNA-binding domain [1]. The domain is involved in plant defence in response to bacterial infection [2,3].


The ~60-residue RAP (an acronym for RNA-binding domain abundant in Apicomplexans) domain is found in various proteins in eukaryotes. It is particularly abundant in apicomplexans and might mediate a range of cellular functions through its potential interactions with RNA [PUBMED:15501674].


  1. Lee I, Hong W; , Trends Biochem Sci 2004;29:567-570.: RAP--a putative RNA-binding domain. PUBMED:15501674 EPMC:15501674 .

  2. Katiyar-Agarwal S, Gao S, Vivian-Smith A, Jin H;, Genes Dev. 2007;21:3123-3134.: A novel class of bacteria-induced small RNAs in Arabidopsis. PUBMED:18003861 EPMC:18003861 .

  3. Katiyar-Agarwal S, Jin H;, Annu Rev Phytopathol. 2010;48:225-246.: Role of small RNAs in host-microbe interactions. PUBMED:20687832 EPMC:20687832.