This domain is found in peptide chain release factors such as RF-1 (P07011) and RF-2 (P07012), and a number of smaller proteins of unknown function such as P40711. This domain contains the peptidyl-tRNA hydrolase activity. The domain contains a highly conserved motif GGQ, where the glutamine is thought to coordinate the water that mediates the hydrolysis.
The mapping between Pfam and Gene Ontology is provided by InterPro. If you use this data please cite InterPro.