EuRBPDB

Cercocebus_atysFamily: RIO1 Number of Genes: 15

Ensembl ID	Symbol	Entrez ID
ENSCATG00000001548	RIOK1	105572495
ENSCATG00000024995	ULK1	105591065
ENSCATG00000028680	HUNK	105575578
ENSCATG00000032072	RPS6KA4	105577485
ENSCATG00000032753	ULK2	105593728
ENSCATG00000033689	MAPK9	105590417
ENSCATG00000033936	DAPK1	105584264
ENSCATG00000035047	RIOK2	105580976
ENSCATG00000038443	RPS6KA5	105596570
ENSCATG00000040119	NUAK1	105573266
ENSCATG00000040824	RIOK3	105583914
ENSCATG00000041855	NEK10	105578269
ENSCATG00000042243	TP53RK	105588519
ENSCATG00000043801	DAPK2	105601038
ENSCATG00000044068	NUAK2	105576394

Introduction

Pfam

This is a family of atypical serine kinases which are found in archaea, bacteria and eukaryotes. Activity of Rio1 is vital in Saccharomyces cerevisiae for the processing of ribosomal RNA, as well as for proper cell cycle progression and chromosome maintenance. The structure of RIO1 has been determined [4].

InterPro

No InterPro abstract

Reference

Krupa A, Srinivasan N; , Protein Sci 2002;11:1580-1584.: Lipopolysaccharide phosphorylating enzymes encoded in the genomes of Gram-negative bacteria are related to the eukaryotic protein kinases. PUBMED:12021457 EPMC:12021457 .
Vanrobays E, Gelugne JP, Gleizes PE, Caizergues-Ferrer M; , Mol Cell Biol 2003;23:2083-2095.: Late cytoplasmic maturation of the small ribosomal subunit requires RIO proteins in Saccharomyces cerevisiae. PUBMED:12612080 EPMC:12612080 .
Geerlings TH, Faber AW, Bister M, Vos JC, Raue HA; , 0;0:0-0.: Rio2p: An evolutionarily conserved, low-abundant protein kinase essential for processing of 20S Pre-rRNA in Saccharomyces cerevisiae. PUBMED:12690111 EPMC:12690111 .
Laronde-Leblanc N, Guszczynski T, Copeland T, Wlodawer A; , FEBS J 2005;272:3698-3713.: Structure and activity of the atypical serine kinase Rio1. PUBMED:16008568 EPMC:16008568.