Saccharomyces_cerevisiaeFamily: RNA12 Number of Genes: 1
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO



This family includes RNA12 from S. cerevisiae. That protein contains an RRM domain. This region is C-terminal to that and includes a P-loop motif suggesting this region binds to NTP. The RNA12 proteins is involved in pre-rRNA maturation [1].


Mitochondrial escape protein 2 (also known as RNA12) plays a role in maintaining the mitochondrial genome and in controlling mtDNA escape [PUBMED:8514129, PUBMED:8649384]. It is also involved in the regulation of mtDNA nucleotide structure and number [PUBMED:16850347]. Additionally, this protein have a dispensable role in the early maturation of pre-rRNA [PUBMED:1557037].


  1. Liang S, Alksne L, Warner JR, Lacroute F; , Mol Gen Genet. 1992;232:304-312.: rna12+, a gene of Saccharomyces cerevisiae involved in pre-rRNA maturation. Characterization of a temperature-sensitive mutant, cloning and sequencing of the gene. PUBMED:1557037 EPMC:1557037.