Saccharomyces_cerevisiaeFamily: RNA_Me_trans Number of Genes: 1
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO



This family of proteins are predicted to be alpha/beta-knot SAM-dependent RNA methyltransferases [1].


This entry represents a group of RNA methyltransferases, including TK0422 from Thermococcus kodakaraensis and Sfm1 from Saccharomyces cerevisiae. TK0422 catalyzes the S-adenosyl-L-methionine-dependent formation of either N(1)-methyladenine or N(1)-methylguanine at position 9 (m1A9 or m1G9) in tRNA [PUBMED:20525789]. Sfm1 (YOR021C) is a S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that monomethylates ribosomal protein S3 (RPS3) at 'Arg-146' [PUBMED:22650761].


  1. Ginalski K, von Grotthuss M, Grishin NV, Rychlewski L; , Nucleic Acids Res. 2004;32:576-581.: Detecting distant homology with Meta-BASIC. PUBMED:15215454 EPMC:15215454.