EuRBPDB

Mus_musculus_c3hhejFamily: RNA_pol_Rpb1_4 Number of Genes: 3
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
Polr2a
-
Polr3a
-
Polr1a
-

Introduction

Pfam

RNA polymerases catalyse the DNA dependent polymerisation of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). This domain, domain 4, represents the funnel domain. The funnel contain the binding site for some elongation factors [1,2].

InterPro

The mapping between Pfam and Gene Ontology is provided by InterPro. If you use this data please cite InterPro.

Reference

  1. Severinov K, Mustaev A, Kukarin A, Muzzin O, Bass I, Darst SA, Goldfarb A; , J Biol Chem 1996;271:27969-27974.: Structural modules of the large subunits of RNA polymerase. Introducing archaebacterial and chloroplast split sites in the beta and beta' subunits of Escherichia coli RNA polymerase. PUBMED:8910400 EPMC:8910400 .

  2. Cramer P, Bushnell DA, Kornberg RD; , Science 2001;292:1863-1876.: Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution. PUBMED:11313498 EPMC:11313498.