EuRBPDB

Gallus_gallusFamily: RNase_Zc3h12a Number of Genes: 5

Ensembl ID	Symbol	Entrez ID
ENSGALG00000002021	ZC3H12A	419618
ENSGALG00000003907	N4BP1	415739
ENSGALG00000017154	ZC3H12C	418963
ENSGALG00000038782	ZC3H12D	421623
ENSGALG00000039391	ZC3H12B	422175

Introduction

Pfam

This domain is found in the Zc3h12a protein which has shown to be a ribonuclease that controls the stability of a set of inflammatory genes [1]. It has been suggested that this domain belongs to the PIN domain superfamily [1]. This domain has also been identified as part of the NYN domain family [2].

InterPro

This domain is found in the Zc3h12a protein which has shown to be a ribonuclease that controls the stability of a set of inflammatory genes [PUBMED:19322177]. It has been suggested that this domain belongs to the PIN domain superfamily [PUBMED:19322177]. This domain has also been identified as part of the NYN domain family [PUBMED:17114934].

Reference

Matsushita K, Takeuchi O, Standley DM, Kumagai Y, Kawagoe T, Miyake T, Satoh T, Kato H, Tsujimura T, Nakamura H, Akira S;, Nature;458:1185-1190.: Zc3h12a is an RNase essential for controlling immune responses by regulating mRNA decay. PUBMED:19322177 EPMC:19322177 .
Anantharaman V, Aravind L; , RNA Biol. 2006; [Epub ahead of print]: The NYN Domains: Novel Predicted RNAses with a PIN Domain-Like Fold. PUBMED:17114934 EPMC:17114934.