Microtus_ochrogasterFamily: SF3b10 Number of Genes: 1
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
Sf3b5

Introduction

Pfam

This family consists of several eukaryotic splicing factor 3B subunit 10 (SF3b10) proteins. SF3b10 is a 10 kDa subunit of the splicing factor SF3b. SF3b associates with the splicing factor SF3a and a 12S RNA unit to form the U2 small nuclear ribonucleoproteins complex. SF3b10 and SF3b14b are also thought to facilitate the interaction of U2 with the branch site [1].

InterPro

This family consists of several eukaryotic splicing factor 3B subunit 5 (SF3b5) proteins. SF3b5 is a 10 kDa subunit of the splicing factor SF3b. SF3b associates with the splicing factor SF3a and a 12S RNA unit to form the U2 small nuclear ribonucleoproteins complex. SF3b5 and SF3b14b are also thought to facilitate the interaction of U2 with the branch site [PUBMED:12234937]. Also included in this entry is RDS3 complex subunit 10, another protein involved in mRNA splicing [PUBMED:15565172].

Reference

  1. Will CL, Urlaub H, Achsel T, Gentzel M, Wilm M, Luhrmann R; , EMBO J 2002;21:4978-4988.: Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein. PUBMED:12234937 EPMC:12234937.