EuRBPDB

Mus_musculus_c3hhejFamily: Seryl_tRNA_N Number of Genes: 2

Ensembl ID	Symbol	Entrez ID	RBD	RBPome	PRI	Expresion	Pathway	Phenotype	Paralog	Ortholog	GO
MGP_C3HHeJ_G0027479	Sars	-
MGP_C3HHeJ_G0031661	Sars2	-

Introduction

Pfam

This domain is found associated with the Pfam tRNA synthetase class II domain (PF00587) and represents the N-terminal domain of seryl-tRNA synthetase.

InterPro

This entry represents the N-terminal domain of Serine-tRNA synthetase, which consists of two helices in a long alpha-hairpin. Serine-tRNA synthetase (EC) exists as monomer and belongs to class IIa aminoacyl-tRNA synthetase [PUBMED:7540217].

Reference

Cusack S, Yaremchuk A, Tukalo M; , EMBO J 1996;15:2834-2842.: The crystal structure of the ternary complex of T.thermophilus seryl-tRNA synthetase with tRNA(Ser) and a seryl-adenylate analogue reveals a conformational switch in the active site. PUBMED:8654381 EPMC:8654381.