| Ensembl ID | Symbol | Entrez ID | RBD | RBPome | PRI | Expresion | Pathway | Phenotype | Paralog | Ortholog | GO |
|---|---|---|---|---|---|---|---|---|---|---|---|
This is a family of the conserved N-terminal end of a group of proteins conserved in fungi. It is likely to be a Sin3 binding protein. Sin3p does not bind DNA directly even though the yeast SIN3 gene functions as a transcriptional repressor. Sin3p is part of a large multiprotein complex [2]. Stb3 appears to bind directly to ribosomal RNA Processing Elements (RRPE) although there are no obvious domains which would accord with this, implying that Stb3 may be a novel RNA-binding protein [1].
This entry represents Sin3 binding proteins conserved in fungi. Sin3p does not bind DNA directly even though the yeast SIN3 gene functions as a transcriptional repressor. Sin3p is part of a large multiprotein complex [PUBMED:9393435]. Stb3 appears to bind directly to ribosomal RNA Processing Elements (RRPE) although there are no obvious domains which would accord with this, implying that Stb3 may be a novel RNA-binding protein [PUBMED:17616518].
Liko D, Slattery MG, Heideman W; , J Biol Chem. 2007; [Epub ahead of print]: Stb3 binds to RRPE motifs that control transcriptional responses to growth in Saccharomyces cerevisiae. PUBMED:17616518 EPMC:17616518 .
Kasten MM, Stillman DJ; , Mol Gen Genet. 1997;256:376-386.: Identification of the Saccharomyces cerevisiae genes STB1-STB5 encoding Sin3p binding proteins. PUBMED:9393435 EPMC:9393435.
