EuRBPDB

Gallus_gallusFamily: Sua5_yciO_yrdC Number of Genes: 3
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
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YRDC
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Introduction

Pfam

This domain has been shown to bind preferentially to dsRNA [1]. The domain is found in SUA5 P32579 as well as HypF and YrdC P45748. It has also been shown to be required for telomere recombniation in yeast.

InterPro

This domain has been shown to bind preferentially to dsRNA [PUBMED:11206077]. This domain is found in Sua5 (SWISSPROT) as well as YrdC (SWISSPROT) and carbamoyltransferase HypF. The YrdC/Sua5 family is required for the formation of threonylcarbamoyladenosine in tRNA [PUBMED:19287007]. Sua5 has been shown to be required for translational regulation [PUBMED:19884342] and telomere recombination in yeast [PUBMED:20309016].

Reference

  1. Teplova M, Tereshko V, Sanishvili R, Joachimiak A, Bushueva T, Anderson WF, Egli M; , Protein Sci 2000;9:2557-2566.: The structure of the yrdC gene product from Escherichia coli reveals a new fold and suggests a role in RNA binding. PUBMED:11206077 EPMC:11206077 .

  2. El Yacoubi B, Lyons B, Cruz Y, Reddy R, Nordin B, Agnelli F, Williamson JR, Schimmel P, Swairjo MA, de Crecy-Lagard V;, Nucleic Acids Res. 2009;37:2894-2909.: The universal YrdC/Sua5 family is required for the formation of threonylcarbamoyladenosine in tRNA. PUBMED:19287007 EPMC:19287007 .

  3. Lin CA, Ellis SR, True HL;, Mol Cell Biol. 2010;30:354-363.: The Sua5 protein is essential for normal translational regulation in yeast. PUBMED:19884342 EPMC:19884342 .

  4. Meng FL, Chen XF, Hu Y, Tang HB, Dang W, Zhou JQ;, Cell Res. 2010;20:495-498.: Sua5p is required for telomere recombination in Saccharomyces cerevisiae. PUBMED:20309016 EPMC:20309016.